Details for: LOC101927131

Gene ID: 101927131

Symbol: LOC101927131

Ensembl ID: ENSG00000262999

Description: uncharacterized LOC101927131

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: 1.7824
    Cell Significance Index: 24.6500
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 0.6884
    Cell Significance Index: 16.6800
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 0.1444
    Cell Significance Index: 1.0500
  • Cell Name: salivary gland cell (CL0009005)
    Fold Change: 0.0564
    Cell Significance Index: 0.7000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.0133
    Cell Significance Index: 1.9400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0085
    Cell Significance Index: 1.5400
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.0067
    Cell Significance Index: 0.3400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0050
    Cell Significance Index: 0.2600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0003
    Cell Significance Index: 0.0400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0001
    Cell Significance Index: 0.2100
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0001
    Cell Significance Index: -0.1700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0009
    Cell Significance Index: -1.4600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0012
    Cell Significance Index: -1.6800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0014
    Cell Significance Index: -0.8700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0021
    Cell Significance Index: -1.5400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0026
    Cell Significance Index: -0.9400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0029
    Cell Significance Index: -2.1700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0036
    Cell Significance Index: -2.0500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0036
    Cell Significance Index: -1.9900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0037
    Cell Significance Index: -0.7400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0041
    Cell Significance Index: -1.8700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0054
    Cell Significance Index: -1.5400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0059
    Cell Significance Index: -0.4500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0069
    Cell Significance Index: -1.3800
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0073
    Cell Significance Index: -0.3000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0104
    Cell Significance Index: -1.4300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0108
    Cell Significance Index: -1.8400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0154
    Cell Significance Index: -1.5700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0154
    Cell Significance Index: -1.7700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0159
    Cell Significance Index: -0.7400
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0183
    Cell Significance Index: -0.2500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0203
    Cell Significance Index: -2.1100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0218
    Cell Significance Index: -1.0300
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0266
    Cell Significance Index: -1.1600
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0333
    Cell Significance Index: -1.8700
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.0344
    Cell Significance Index: -0.7000
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0356
    Cell Significance Index: -0.9700
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0440
    Cell Significance Index: -1.5400
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.0464
    Cell Significance Index: -0.6600
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0498
    Cell Significance Index: -1.0900
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0525
    Cell Significance Index: -1.7200
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0534
    Cell Significance Index: -1.7000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0545
    Cell Significance Index: -2.4100
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0549
    Cell Significance Index: -1.4700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0562
    Cell Significance Index: -1.6100
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.0568
    Cell Significance Index: -1.0500
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.0575
    Cell Significance Index: -1.7000
  • Cell Name: granulocyte (CL0000094)
    Fold Change: -0.0589
    Cell Significance Index: -0.7100
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0631
    Cell Significance Index: -1.3200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0634
    Cell Significance Index: -2.4000
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0640
    Cell Significance Index: -1.6300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0648
    Cell Significance Index: -1.7300
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0673
    Cell Significance Index: -1.6800
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0705
    Cell Significance Index: -1.8000
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.0728
    Cell Significance Index: -1.0100
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0728
    Cell Significance Index: -1.4200
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0731
    Cell Significance Index: -1.5800
  • Cell Name: myoepithelial cell (CL0000185)
    Fold Change: -0.0767
    Cell Significance Index: -0.8700
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.0781
    Cell Significance Index: -1.6300
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0813
    Cell Significance Index: -1.7300
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.0831
    Cell Significance Index: -1.4000
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0839
    Cell Significance Index: -1.6900
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -0.0858
    Cell Significance Index: -1.1000
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.0873
    Cell Significance Index: -2.7600
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.0873
    Cell Significance Index: -1.4000
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0874
    Cell Significance Index: -1.2900
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.0899
    Cell Significance Index: -1.7700
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0900
    Cell Significance Index: -1.7800
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.0908
    Cell Significance Index: -1.5700
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0916
    Cell Significance Index: -1.9000
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: -0.0919
    Cell Significance Index: -1.3400
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.0923
    Cell Significance Index: -0.8500
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.0923
    Cell Significance Index: -1.8400
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: -0.0941
    Cell Significance Index: -1.1900
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0950
    Cell Significance Index: -1.3600
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.0955
    Cell Significance Index: -2.3300
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.0956
    Cell Significance Index: -1.8700
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: -0.0963
    Cell Significance Index: -1.4400
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0969
    Cell Significance Index: -1.6600
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: -0.0971
    Cell Significance Index: -1.4200
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: -0.0983
    Cell Significance Index: -1.6800
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0998
    Cell Significance Index: -1.6700
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: -0.1000
    Cell Significance Index: -1.6200
  • Cell Name: stromal cell of endometrium (CL0002255)
    Fold Change: -0.1005
    Cell Significance Index: -1.4300
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.1007
    Cell Significance Index: -1.5300
  • Cell Name: pulmonary capillary endothelial cell (CL4028001)
    Fold Change: -0.1022
    Cell Significance Index: -1.4000
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: -0.1028
    Cell Significance Index: -1.2500
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.1045
    Cell Significance Index: -2.6100
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.1064
    Cell Significance Index: -1.7900
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: -0.1065
    Cell Significance Index: -1.0300
  • Cell Name: neutrophil (CL0000775)
    Fold Change: -0.1081
    Cell Significance Index: -1.3500
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: -0.1100
    Cell Significance Index: -1.2400
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: -0.1100
    Cell Significance Index: -0.6000
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.1107
    Cell Significance Index: -1.8800
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: -0.1135
    Cell Significance Index: -1.5300
  • Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
    Fold Change: -0.1136
    Cell Significance Index: -1.2400
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: -0.1149
    Cell Significance Index: -1.3300
  • Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
    Fold Change: -0.1159
    Cell Significance Index: -1.2800
  • Cell Name: suprabasal keratinocyte (CL4033013)
    Fold Change: -0.1163
    Cell Significance Index: -1.8700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Broad Tissue Expression:** LOC101927131 is significantly expressed in diverse cell types, including blood vessel endothelial cells, cardiac endothelial cells, immune cells, and neural precursors, highlighting its potential role in tissue-specific processes. 2. **Pleiotropic Function:** The gene's expression in multiple cell types suggests a non-redundant function, underscoring the importance of further investigation to understand its molecular mechanisms. 3. **Cell Type-Specific Expression:** The gene's expression in specific cell types, such as intestinal crypt stem cells and goblet cells, indicates a specialized role in maintaining tissue homeostasis. **Pathways and Functions:** 1. **Endothelial Cell Function:** LOC101927131 may play a role in maintaining endothelial cell integrity, regulating vascular permeability, or modulating angiogenesis. 2. **Immune Cell Regulation:** The gene's expression in immune cells, such as innate lymphoid cells and lymphoid lineage-restricted progenitors, suggests involvement in immune cell development, maturation, or function. 3. **Neural Development:** LOC101927131's expression in neural precursors, including GABAergic interneurons and radial glial cells, implies a role in neural development, synaptic transmission, or neuronal function. 4. **Tissue Homeostasis:** The gene's expression in absorptive cells and intestinal crypt stem cells suggests a role in maintaining tissue homeostasis, regulating nutrient absorption, or promoting epithelial barrier function. **Clinical Significance:** 1. **Disease Association:** Further investigation may reveal associations between LOC101927131 dysregulation and various diseases, such as cardiovascular disorders, autoimmune conditions, or neurological disorders. 2. **Therapeutic Targeting:** Understanding the gene's functions and mechanisms may lead to the identification of novel therapeutic targets for treating diseases associated with LOC101927131 dysfunction. 3. **Basic Research Implications:** The study of LOC101927131 has implications for our understanding of tissue-specific gene regulation, cellular differentiation, and the molecular mechanisms underlying various biological processes. In conclusion, LOC101927131 is a gene of uncharacterized function, exhibiting a complex pattern of tissue-specific expression. Further investigation is necessary to unravel the molecular mechanisms underlying its functions and to explore its potential clinical significance.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.