Details for: SAP30BP AS1

Gene ID: 128667226

Symbol: SAP30BP AS1

Ensembl ID: ENSG00000264270

Description: SAP30BP antisense RNA 1

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1446
    Cell Significance Index: 6.7400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.1121
    Cell Significance Index: 3.2300
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: 0.0851
    Cell Significance Index: 1.2000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0739
    Cell Significance Index: 4.6600
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 0.0546
    Cell Significance Index: 1.1100
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 0.0493
    Cell Significance Index: 0.3800
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0289
    Cell Significance Index: 1.5000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0282
    Cell Significance Index: 0.6000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0278
    Cell Significance Index: 1.2600
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.0193
    Cell Significance Index: 0.2500
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.0167
    Cell Significance Index: 0.2500
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: 0.0116
    Cell Significance Index: 0.1400
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 0.0040
    Cell Significance Index: 0.1000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0030
    Cell Significance Index: 0.5400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0029
    Cell Significance Index: 0.5700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.0023
    Cell Significance Index: 0.2600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0020
    Cell Significance Index: 0.0700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0013
    Cell Significance Index: 0.1600
  • Cell Name: granulocyte (CL0000094)
    Fold Change: 0.0008
    Cell Significance Index: 0.0100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0006
    Cell Significance Index: 0.1300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0004
    Cell Significance Index: 0.0500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0000
    Cell Significance Index: -0.0800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0001
    Cell Significance Index: -0.0800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0002
    Cell Significance Index: -0.3500
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0002
    Cell Significance Index: -0.0100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0003
    Cell Significance Index: -0.5700
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0004
    Cell Significance Index: -0.4900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0005
    Cell Significance Index: -0.2900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0006
    Cell Significance Index: -0.3600
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0008
    Cell Significance Index: -0.0400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0009
    Cell Significance Index: -0.3300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0010
    Cell Significance Index: -0.4700
  • Cell Name: glandular epithelial cell (CL0000150)
    Fold Change: -0.0013
    Cell Significance Index: -0.0100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0016
    Cell Significance Index: -0.4500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0019
    Cell Significance Index: -0.2800
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0023
    Cell Significance Index: -0.0800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0024
    Cell Significance Index: -1.7500
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: -0.0036
    Cell Significance Index: -0.0400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0043
    Cell Significance Index: -0.3300
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0051
    Cell Significance Index: -0.5200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0052
    Cell Significance Index: -0.5400
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0057
    Cell Significance Index: -0.1800
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: -0.0062
    Cell Significance Index: -0.0900
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0072
    Cell Significance Index: -0.2400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0082
    Cell Significance Index: -1.4000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0088
    Cell Significance Index: -0.5700
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -0.0090
    Cell Significance Index: -0.1200
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0090
    Cell Significance Index: -0.3700
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.0091
    Cell Significance Index: -0.1900
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0092
    Cell Significance Index: -0.1900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0095
    Cell Significance Index: -0.4500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0096
    Cell Significance Index: -0.5400
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0103
    Cell Significance Index: -0.1400
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0104
    Cell Significance Index: -0.2600
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: -0.0114
    Cell Significance Index: -0.1100
  • Cell Name: fast muscle cell (CL0000190)
    Fold Change: -0.0122
    Cell Significance Index: -0.1600
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.0123
    Cell Significance Index: -0.1700
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.0123
    Cell Significance Index: -0.2900
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.0124
    Cell Significance Index: -0.2200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0124
    Cell Significance Index: -0.5500
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0161
    Cell Significance Index: -0.6100
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.0166
    Cell Significance Index: -0.4900
  • Cell Name: CD141-positive myeloid dendritic cell (CL0002394)
    Fold Change: -0.0166
    Cell Significance Index: -0.1800
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.0168
    Cell Significance Index: -0.2600
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0170
    Cell Significance Index: -0.3600
  • Cell Name: myofibroblast cell (CL0000186)
    Fold Change: -0.0172
    Cell Significance Index: -0.1800
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: -0.0174
    Cell Significance Index: -0.2600
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0176
    Cell Significance Index: -0.3800
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.0176
    Cell Significance Index: -0.3500
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0177
    Cell Significance Index: -0.3600
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0182
    Cell Significance Index: -0.2600
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.0183
    Cell Significance Index: -0.3600
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0184
    Cell Significance Index: -0.4700
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.0191
    Cell Significance Index: -0.2500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0195
    Cell Significance Index: -0.5300
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.0195
    Cell Significance Index: -0.2600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0199
    Cell Significance Index: -0.5700
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0212
    Cell Significance Index: -0.4200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0213
    Cell Significance Index: -0.5700
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.0235
    Cell Significance Index: -0.5700
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.0240
    Cell Significance Index: -0.4700
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.0243
    Cell Significance Index: -0.4500
  • Cell Name: cell of skeletal muscle (CL0000188)
    Fold Change: -0.0265
    Cell Significance Index: -0.3400
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.0267
    Cell Significance Index: -0.3800
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: -0.0272
    Cell Significance Index: -0.4400
  • Cell Name: ciliated epithelial cell (CL0000067)
    Fold Change: -0.0273
    Cell Significance Index: -0.2700
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.0289
    Cell Significance Index: -1.0600
  • Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
    Fold Change: -0.0290
    Cell Significance Index: -0.3200
  • Cell Name: retinal pigment epithelial cell (CL0002586)
    Fold Change: -0.0293
    Cell Significance Index: -0.3200
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.0294
    Cell Significance Index: -0.9300
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: -0.0302
    Cell Significance Index: -0.3400
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: -0.0317
    Cell Significance Index: -0.4100
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: -0.0325
    Cell Significance Index: -0.4000
  • Cell Name: common dendritic progenitor (CL0001029)
    Fold Change: -0.0327
    Cell Significance Index: -0.3400
  • Cell Name: decidual natural killer cell, human (CL0002343)
    Fold Change: -0.0329
    Cell Significance Index: -0.3400
  • Cell Name: L5/6 near-projecting glutamatergic neuron of the primary motor cortex (CL4023043)
    Fold Change: -0.0336
    Cell Significance Index: -0.3400
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: -0.0337
    Cell Significance Index: -0.4600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0337
    Cell Significance Index: -0.7300
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.0347
    Cell Significance Index: -0.3200
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.0350
    Cell Significance Index: -0.8600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** SAP30BP AS1 is a non-coding RNA transcript, specifically an antisense RNA, which implies that it is transcribed from a different strand of DNA compared to the sense RNA transcript SAP30BP. This antisense RNA has been found to be significantly expressed in various cell types, including those involved in immune responses, such as blood vessel endothelial cells and goblet cells. The expression of SAP30BP AS1 is often associated with cell proliferation, differentiation, and survival, suggesting a role in maintaining tissue homeostasis. **Pathways and Functions:** The mechanisms by which SAP30BP AS1 exerts its effects are multifaceted and involve various signaling pathways. SAP30BP AS1 has been shown to interact with the SAP30BP protein, a member of the 30-kDa subunit of the histone deacetylase complex, which plays a crucial role in regulating gene expression by modifying chromatin structure. Through this interaction, SAP30BP AS1 may modulate the activity of histone deacetylases, influencing the expression of genes involved in cell proliferation, differentiation, and survival. Furthermore, SAP30BP AS1 has been implicated in the regulation of the Wnt/β-catenin signaling pathway, which is critical for maintaining tissue homeostasis and preventing cancer. The expression of SAP30BP AS1 has been shown to inhibit the activity of β-catenin, a key component of the Wnt/β-catenin pathway, thereby preventing the activation of genes involved in cell proliferation and differentiation. **Clinical Significance:** The clinical significance of SAP30BP AS1 is multifaceted, with potential implications for various diseases, including cancer, autoimmune disorders, and neurodegenerative diseases. The expression of SAP30BP AS1 has been found to be altered in various types of cancer, including colon cancer, suggesting a potential role in tumorigenesis. Furthermore, SAP30BP AS1 has been implicated in the regulation of immune responses, with potential implications for the treatment of autoimmune disorders, such as rheumatoid arthritis. In addition, the expression of SAP30BP AS1 has been found to be altered in neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, suggesting a potential role in the pathogenesis of these diseases. The identification of SAP30BP AS1 as a critical regulator of cell proliferation, differentiation, and survival provides new insights into its potential as a therapeutic target for various diseases. In conclusion, SAP30BP AS1 is a multifaceted gene that plays a critical role in maintaining tissue homeostasis and preventing disease progression. Its expression is significantly altered in various cell types, including those involved in immune responses, and its interaction with the SAP30BP protein and the Wnt/β-catenin signaling pathway suggests a complex regulatory mechanism. The clinical significance of SAP30BP AS1 is multifaceted, with potential implications for various diseases, including cancer, autoimmune disorders, and neurodegenerative diseases. Further research is needed to fully elucidate the mechanisms by which SAP30BP AS1 exerts its effects and to explore its potential as a therapeutic target.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.