Details for: DYNC1I1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 238.7998
Cell Significance Index: -60.5700 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 48.8014
Cell Significance Index: -60.1700 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 15.3445
Cell Significance Index: -60.5500 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 9.8374
Cell Significance Index: -21.5300 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 5.0759
Cell Significance Index: 144.8500 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 4.4365
Cell Significance Index: 168.0000 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 4.3699
Cell Significance Index: 193.2900 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 4.1646
Cell Significance Index: 280.0300 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 3.8359
Cell Significance Index: 235.1800 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 3.5184
Cell Significance Index: 43.6400 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 3.3560
Cell Significance Index: 1203.7300 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 3.2181
Cell Significance Index: 645.5400 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 3.2156
Cell Significance Index: 4950.2800 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 3.1613
Cell Significance Index: 242.5900 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 2.9928
Cell Significance Index: 2069.9200 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 2.2059
Cell Significance Index: 4068.3000 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 2.1678
Cell Significance Index: 2947.5900 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 1.7446
Cell Significance Index: 44.8500 - Cell Name: hippocampal interneuron (CL1001569)
Fold Change: 1.6725
Cell Significance Index: 21.6900 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 1.3148
Cell Significance Index: 2475.6200 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.2251
Cell Significance Index: 55.5300 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: 1.0600
Cell Significance Index: 14.1400 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 1.0390
Cell Significance Index: 197.7300 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 1.0286
Cell Significance Index: 63.2200 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 0.9309
Cell Significance Index: 96.9300 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.8975
Cell Significance Index: 15.3800 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.8616
Cell Significance Index: 27.6000 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.8493
Cell Significance Index: 18.4000 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 0.6783
Cell Significance Index: 10.3200 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.6510
Cell Significance Index: 295.4700 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.5878
Cell Significance Index: 530.7000 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.5617
Cell Significance Index: 13.4700 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.4533
Cell Significance Index: 44.8500 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.4176
Cell Significance Index: 53.5300 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.3859
Cell Significance Index: 245.0900 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.2759
Cell Significance Index: 49.7500 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.2588
Cell Significance Index: 51.3700 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: 0.2133
Cell Significance Index: 2.6600 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.1761
Cell Significance Index: 28.6400 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 0.0113
Cell Significance Index: 1.6400 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0013
Cell Significance Index: -0.7100 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0097
Cell Significance Index: -0.3400 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0167
Cell Significance Index: -10.4300 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0175
Cell Significance Index: -12.9800 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0498
Cell Significance Index: -28.1000 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -0.0597
Cell Significance Index: -0.6500 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0743
Cell Significance Index: -54.4900 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.0755
Cell Significance Index: -2.1800 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0900
Cell Significance Index: -68.1600 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: -0.0973
Cell Significance Index: -10.5800 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.1058
Cell Significance Index: -46.7600 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1566
Cell Significance Index: -32.9900 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1677
Cell Significance Index: -48.2400 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.2004
Cell Significance Index: -34.2200 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.2480
Cell Significance Index: -30.5000 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: -0.2567
Cell Significance Index: -3.2400 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.3123
Cell Significance Index: -9.9500 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.3401
Cell Significance Index: -46.7100 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.3690
Cell Significance Index: -43.0000 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.3718
Cell Significance Index: -25.7200 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.3736
Cell Significance Index: -7.9300 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.3857
Cell Significance Index: -24.3100 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.3950
Cell Significance Index: -7.8100 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.4038
Cell Significance Index: -13.2200 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.4405
Cell Significance Index: -56.9100 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.4630
Cell Significance Index: -24.3100 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.4847
Cell Significance Index: -9.7300 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.5573
Cell Significance Index: -13.9300 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.5632
Cell Significance Index: -64.5200 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.5665
Cell Significance Index: -64.6700 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.5776
Cell Significance Index: -59.0100 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: -0.6085
Cell Significance Index: -5.7900 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.6299
Cell Significance Index: -9.3000 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: -0.6336
Cell Significance Index: -4.8600 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -0.6413
Cell Significance Index: -38.5000 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.6712
Cell Significance Index: -29.1900 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.7253
Cell Significance Index: -15.6700 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: -0.7559
Cell Significance Index: -10.8600 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.7678
Cell Significance Index: -54.3000 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.7971
Cell Significance Index: -11.4200 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.8016
Cell Significance Index: -59.7400 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.8164
Cell Significance Index: -42.5300 - Cell Name: neural cell (CL0002319)
Fold Change: -0.8173
Cell Significance Index: -9.5400 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.8358
Cell Significance Index: -29.2800 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.8463
Cell Significance Index: -21.1100 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.8706
Cell Significance Index: -24.3300 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.8976
Cell Significance Index: -50.3700 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: -0.9200
Cell Significance Index: -11.6100 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.9217
Cell Significance Index: -47.8800 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.9683
Cell Significance Index: -62.4700 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: -1.0076
Cell Significance Index: -12.9200 - Cell Name: neuron (CL0000540)
Fold Change: -1.0317
Cell Significance Index: -9.7800 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -1.0807
Cell Significance Index: -50.7900 - Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
Fold Change: -1.1049
Cell Significance Index: -12.1900 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -1.1700
Cell Significance Index: -24.2700 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -1.2505
Cell Significance Index: -39.5500 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -1.2522
Cell Significance Index: -58.3900 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -1.2573
Cell Significance Index: -26.2400 - Cell Name: retinal bipolar neuron (CL0000748)
Fold Change: -1.2787
Cell Significance Index: -15.5000 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: -1.3003
Cell Significance Index: -15.5500
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3966672870
Symbol: DC1I1_HUMAN
Name: Cytoplasmic dynein 1 intermediate chain 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10049579
Title: Cloning and characterization of two cytoplasmic dynein intermediate chain genes in mouse and human.
PubMed ID: 10049579
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 12853948
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 19229290
Title: Dynein light intermediate chain 1 is required for progress through the spindle assembly checkpoint.
PubMed ID: 19229290
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 27502274
Title: Molecular basis for the protein recognition specificity of the dynein light chain DYNLT1/Tctex1: characterization of the interaction with activin receptor IIB.
PubMed ID: 27502274
PubMed ID: 21248752
Title: Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma.
PubMed ID: 21248752
DOI: 10.1038/nature09639
Sequence Information:
- Length: 645
- Mass: 72955
- Checksum: 55A6FF971E632DA0
- Sequence:
MSDKSDLKAE LERKKQRLAQ IREEKKRKEE ERKKKEADMQ QKKEPVQDDS DLDRKRRETE ALLQSIGISP EPPLVQPLHF LTWDTCYFHY LVPTPMSPSS KSVSTPSEAG SQDSGDLGPL TRTLQWDTDP SVLQLQSDSE LGRRLHKLGV SKVTQVDFLP REVVSYSKET QTPLATHQSE EDEEDEEMVE SKVGQDSELE NQDKKQEVKE APPRELTEEE KQQILHSEEF LIFFDRTIRV IERALAEDSD IFFDYSGREL EEKDGDVQAG ANLSFNRQFY DEHWSKHRVV TCMDWSLQYP ELMVASYNNN EDAPHEPDGV ALVWNMKFKK TTPEYVFHCQ SSVMSVCFAR FHPNLVVGGT YSGQIVLWDN RSHRRTPVQR TPLSAAAHTH PVYCVNVVGT QNAHNLITVS TDGKMCSWSL DMLSTPQESM ELVYNKSKPV AVTGMAFPTG DVNNFVVGSE EGTVYTACRH GSKAGIGEVF EGHQGPVTGI NCHMAVGPID FSHLFVTSSF DWTVKLWTTK HNKPLYSFED NADYVYDVMW SPVHPALFAC VDGMGRLDLW NLNNDTEVPT ASVAIEGASA LNRVRWAQAG KEVAVGDSEG RIWVYDVGEL AVPHNDEWTR FARTLVEIRA NRADSEEEGT VELSA
Genular Protein ID: 3788713155
Symbol: Q8N542_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 628
- Mass: 70707
- Checksum: 479FBF78061C8E09
- Sequence:
MSDKSDLKAE LERKKQRLAQ IREEKKRKEE ERKKKEADMQ QKKEPVQDDS DLDRKRRETE ALLQSIGISP EPPLVPTPMS PSSKSVSTPS EAGSQDSGDL GPLTRTLQWD TDPSVLQLQS DSELGRRLHK LGVSKVTQVD FLPREVVSYS KETQTPLATH QSEEDEEDEE MVESKVGQDS ELENQDKKQE VKEAPPRELT EEEKQQIIHS EEFLIFFDRT IRVIERALAE DSDIFFDYSG RELEEKDGDV QAGANLSFNR QFYDEHCSKH RVVTCMDWSL QYPELMVASY NNNEDAPHEP DGVALVWNMK FKKTTPEYVF HCQSSVMSVC FARFHPNLVV GGTYSGQIVL WDNRSHRRTP VQRTPLSAAA HTHPVYCVNV VGTQNAHNLI TVSTDGKMCS WSLDMLSTPQ ESMELVYNKS KPVAVTGMAF PTGDVNNFVV GSEEGTVYTA CRHGSKAGIG EVFEGHQGPV TGINCHMAVG PIDFSHLFVT SSFDWTVKLW TTKHNKPLYS FEDNADYVYD VMWSPVHPAL FACVDGMGRL DLWNLNNDTE VPTASVAIEG ASALNRVRWA QAGKEVAVGD SEGRIWVYDV GELAVPHNDE WTRFARTLVE IRANRADSEE EGTVELSA
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.