Details for: DSCAM
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: stellate neuron (CL0000122)
Fold Change: 8.65
Marker Score: 46,492 - Cell Name: granule cell (CL0000120)
Fold Change: 7.99
Marker Score: 60,278 - Cell Name: macroglial cell (CL0000126)
Fold Change: 7.55
Marker Score: 17,356 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 6.19
Marker Score: 209,023 - Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: 4.73
Marker Score: 24,789 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 4.45
Marker Score: 5,551 - Cell Name: epithelial cell of alveolus of lung (CL0010003)
Fold Change: 4.04
Marker Score: 1,811 - Cell Name: neuronal brush cell (CL0000555)
Fold Change: 3.25
Marker Score: 10,909 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 3.07
Marker Score: 3,800 - Cell Name: mature microglial cell (CL0002629)
Fold Change: 3
Marker Score: 1,086 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 2.99
Marker Score: 1,148 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 2.98
Marker Score: 5,007 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 2.97
Marker Score: 8,467 - Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 2.96
Marker Score: 1,471 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 2.88
Marker Score: 13,319 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 2.87
Marker Score: 22,007 - Cell Name: retinal cone cell (CL0000573)
Fold Change: 2.87
Marker Score: 8,223 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 2.74
Marker Score: 104,094 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 2.73
Marker Score: 40,790 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 2.62
Marker Score: 1,097 - Cell Name: bipolar neuron (CL0000103)
Fold Change: 2.51
Marker Score: 843 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 2.5
Marker Score: 4,744 - Cell Name: brainstem motor neuron (CL2000047)
Fold Change: 2.37
Marker Score: 1,374 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.36
Marker Score: 9,131 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 2.2
Marker Score: 20,661 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 2.09
Marker Score: 21,545 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.08
Marker Score: 127,941 - Cell Name: neuron (CL0000540)
Fold Change: 2.05
Marker Score: 8,334 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 1.99
Marker Score: 1,115 - Cell Name: ganglion interneuron (CL0000397)
Fold Change: 1.98
Marker Score: 602 - Cell Name: syncytiotrophoblast cell (CL0000525)
Fold Change: 1.97
Marker Score: 1,616 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 1.95
Marker Score: 534 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.93
Marker Score: 18,315 - Cell Name: CNS interneuron (CL0000402)
Fold Change: 1.89
Marker Score: 910 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.88
Marker Score: 16,149 - Cell Name: endocrine cell (CL0000163)
Fold Change: 1.84
Marker Score: 953 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 1.7
Marker Score: 3,465 - Cell Name: monocyte (CL0000576)
Fold Change: 1.68
Marker Score: 2,179 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.65
Marker Score: 2,547 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 1.61
Marker Score: 503 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.6
Marker Score: 59,097 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 1.56
Marker Score: 31,124 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 1.54
Marker Score: 1,015 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 1.44
Marker Score: 1,659 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 1.37
Marker Score: 867 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 1.33
Marker Score: 798 - Cell Name: macrophage (CL0000235)
Fold Change: 1.3
Marker Score: 1,450 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 1.29
Marker Score: 27,549 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 1.25
Marker Score: 749 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.25
Marker Score: 19,613 - Cell Name: astrocyte (CL0000127)
Fold Change: 1.16
Marker Score: 1,004 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: 1.1
Marker Score: 4,593 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 1.1
Marker Score: 4,549 - Cell Name: dendritic cell (CL0000451)
Fold Change: 1.05
Marker Score: 717 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 1.04
Marker Score: 796 - Cell Name: T cell (CL0000084)
Fold Change: 1.02
Marker Score: 1,765 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,758 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 47,983 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,404 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.97
Marker Score: 2,294 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 0.97
Marker Score: 893 - Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
Fold Change: 0.96
Marker Score: 210 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,413 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.93
Marker Score: 5,299 - Cell Name: microglial cell (CL0000129)
Fold Change: 0.92
Marker Score: 1,673 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2,740 - Cell Name: kidney collecting duct intercalated cell (CL1001432)
Fold Change: 0.91
Marker Score: 1,512 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 0.91
Marker Score: 2,595 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 0.9
Marker Score: 2,151 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,283 - Cell Name: glial cell (CL0000125)
Fold Change: 0.85
Marker Score: 937 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.83
Marker Score: 394 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: 0.8
Marker Score: 8,064 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 0.78
Marker Score: 202 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1,263 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.77
Marker Score: 400 - Cell Name: brush cell (CL0002204)
Fold Change: 0.77
Marker Score: 703 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.76
Marker Score: 502 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.75
Marker Score: 1,646 - Cell Name: myeloid cell (CL0000763)
Fold Change: 0.72
Marker Score: 1,157 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.71
Marker Score: 182 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: 0.7
Marker Score: 408 - Cell Name: classical monocyte (CL0000860)
Fold Change: 0.67
Marker Score: 2,787 - Cell Name: visceromotor neuron (CL0005025)
Fold Change: 0.66
Marker Score: 192 - Cell Name: hepatocyte (CL0000182)
Fold Change: 0.64
Marker Score: 438 - Cell Name: meningeal macrophage (CL0000879)
Fold Change: 0.64
Marker Score: 179 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.64
Marker Score: 3,819 - Cell Name: melanocyte (CL0000148)
Fold Change: 0.63
Marker Score: 254 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.61
Marker Score: 2,571 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.61
Marker Score: 485 - Cell Name: neuronal receptor cell (CL0000006)
Fold Change: 0.59
Marker Score: 261 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.57
Marker Score: 151 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: 0.57
Marker Score: 555 - Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 0.56
Marker Score: 230 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 0.56
Marker Score: 235 - Cell Name: B cell (CL0000236)
Fold Change: 0.55
Marker Score: 521 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.54
Marker Score: 314 - Cell Name: photoreceptor cell (CL0000210)
Fold Change: 0.53
Marker Score: 400 - Cell Name: goblet cell (CL0000160)
Fold Change: 0.52
Marker Score: 3,461 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.51
Marker Score: 615
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1583329412
Symbol: DSCAM_HUMAN
Name: CHD2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9426258
Title: DSCAM: a novel member of the immunoglobulin superfamily maps in a Down syndrome region and is involved in the development of the nervous system.
PubMed ID: 9426258
DOI: 10.1093/hmg/7.2.227
PubMed ID: 10925149
Title: Down syndrome cell adhesion molecule DSCAM mediates homophilic intercellular adhesion.
PubMed ID: 10925149
PubMed ID: 10830953
PubMed ID: 15169762
Title: The Down syndrome cell adhesion molecule (DSCAM) interacts with and activates Pak.
PubMed ID: 15169762
PubMed ID: 26048998
Title: The Down syndrome cell adhesion molecule (DSCAM) interacts with and activates Pak.
PubMed ID: 26048998
PubMed ID: 18585357
Title: DSCAM is a netrin receptor that collaborates with DCC in mediating turning responses to netrin-1.
PubMed ID: 18585357
PubMed ID: 19196994
Title: DSCAM functions as a netrin receptor in commissural axon pathfinding.
PubMed ID: 19196994
PubMed ID: 22685302
Title: Down syndrome cell adhesion molecule (DSCAM) associates with uncoordinated-5C (UNC5C) in netrin-1-mediated growth cone collapse.
PubMed ID: 22685302
Sequence Information:
- Length: 2012
- Mass: 222260
- Checksum: 0E33CFB781A08334
- Sequence:
MWILALSLFQ SFANVFSEDL HSSLYFVNAS LQEVVFASTT GTLVPCPAAG IPPVTLRWYL ATGEEIYDVP GIRHVHPNGT LQIFPFPPSS FSTLIHDNTY YCTAENPSGK IRSQDVHIKA VLREPYTVRV EDQKTMRGNV AVFKCIIPSS VEAYITVVSW EKDTVSLVSG SRFLITSTGA LYIKDVQNED GLYNYRCITR HRYTGETRQS NSARLFVSDP ANSAPSILDG FDHRKAMAGQ RVELPCKALG HPEPDYRWLK DNMPLELSGR FQKTVTGLLI ENIRPSDSGS YVCEVSNRYG TAKVIGRLYV KQPLKATISP RKVKSSVGSQ VSLSCSVTGT EDQELSWYRN GEILNPGKNV RITGINHENL IMDHMVKSDG GAYQCFVRKD KLSAQDYVQV VLEDGTPKII SAFSEKVVSP AEPVSLMCNV KGTPLPTITW TLDDDPILKG GSHRISQMIT SEGNVVSYLN ISSSQVRDGG VYRCTANNSA GVVLYQARIN VRGPASIRPM KNITAIAGRD TYIHCRVIGY PYYSIKWYKN SNLLPFNHRQ VAFENNGTLK LSDVQKEVDE GEYTCNVLVQ PQLSTSQSVH VTVKVPPFIQ PFEFPRFSIG QRVFIPCVVV SGDLPITITW QKDGRPIPGS LGVTIDNIDF TSSLRISNLS LMHNGNYTCI ARNEAAAVEH QSQLIVRVPP KFVVQPRDQD GIYGKAVILN CSAEGYPVPT IVWKFSKGAG VPQFQPIALN GRIQVLSNGS LLIKHVVEED SGYYLCKVSN DVGADVSKSM YLTVKIPAMI TSYPNTTLAT QGQKKEMSCT AHGEKPIIVR WEKEDRIINP EMARYLVSTK EVGEEVISTL QILPTVREDS GFFSCHAINS YGEDRGIIQL TVQEPPDPPE IEIKDVKART ITLRWTMGFD GNSPITGYDI ECKNKSDSWD SAQRTKDVSP QLNSATIIDI HPSSTYSIRM YAKNRIGKSE PSNELTITAD EAAPDGPPQE VHLEPISSQS IRVTWKAPKK HLQNGIIRGY QIGYREYSTG GNFQFNIISV DTSGDSEVYT LDNLNKFTQY GLVVQACNRA GTGPSSQEII TTTLEDVPSY PPENVQAIAT SPESISISWS TLSKEALNGI LQGFRVIYWA NLMDGELGEI KNITTTQPSL ELDGLEKYTN YSIQVLAFTR AGDGVRSEQI FTRTKEDVPG PPAGVKAAAA SASMVFVSWL PPLKLNGIIR KYTVFCSHPY PTVISEFEAS PDSFSYRIPN LSRNRQYSVW VVAVTSAGRG NSSEIITVEP LAKAPARILT FSGTVTTPWM KDIVLPCKAV GDPSPAVKWM KDSNGTPSLV TIDGRRSIFS NGSFIIRTVK AEDSGYYSCI ANNNWGSDEI ILNLQVQVPP DQPRLTVSKT TSSSITLSWL PGDNGGSSIR GYILQYSEDN SEQWGSFPIS PSERSYRLEN LKCGTWYKFT LTAQNGVGPG RISEIIEAKT LGKEPQFSKE QELFASINTT RVRLNLIGWN DGGCPITSFT LEYRPFGTTV WTTAQRTSLS KSYILYDLQE ATWYELQMRV CNSAGCAEKQ ANFATLNYDG STIPPLIKSV VQNEEGLTTN EGLKMLVTIS CILVGVLLLF VLLLVVRRRR REQRLKRLRD AKSLAEMLMS KNTRTSDTLS KQQQTLRMHI DIPRAQLLIE ERDTMETIDD RSTVLLTDAD FGEAAKQKSL TVTHTVHYQS VSQATGPLVD VSDARPGTNP TTRRNAKAGP TARNRYASQW TLNRPHPTIS AHTLTTDWRL PTPRAAGSVD KESDSYSVSP SQDTDRARSS MVSTESASST YEELARAYEH AKMEEQLRHA KFTITECFIS DTSSEQLTAG TNEYTDSLTS STPSESGICR FTASPPKPQD GGRVMNMAVP KAHRPGDLIH LPPYLRMDFL LNRGGPGTSR DLSLGQACLE PQKSRTLKRP TVLEPIPMEA ASSASSTREG QSWQPGAVAT LPQREGAELG QAAKMSSSQE SLLDSRGHLK GNNPYAKSYT LV
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.