Details for: PHC1

Gene ID: 1911

Symbol: PHC1

Ensembl ID: ENSG00000111752

Description: polyhomeotic homolog 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 134.1089
    Cell Significance Index: -20.8600
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 78.6340
    Cell Significance Index: -19.9500
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 41.3285
    Cell Significance Index: -16.7900
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 17.6644
    Cell Significance Index: -16.8700
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 17.0890
    Cell Significance Index: -21.0700
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 7.5853
    Cell Significance Index: -20.3200
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 5.3535
    Cell Significance Index: -21.1300
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 4.8462
    Cell Significance Index: -14.8900
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 1.5543
    Cell Significance Index: 11.9800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.9501
    Cell Significance Index: 857.8500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.8976
    Cell Significance Index: 180.0500
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.8226
    Cell Significance Index: 133.7800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.7686
    Cell Significance Index: 275.6800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.6389
    Cell Significance Index: 24.2000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.5949
    Cell Significance Index: 12.6700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.5740
    Cell Significance Index: 25.3900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.5135
    Cell Significance Index: 55.8600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.4214
    Cell Significance Index: 25.9000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.3682
    Cell Significance Index: 20.6600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.3670
    Cell Significance Index: 23.1300
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.3649
    Cell Significance Index: 7.9900
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.3578
    Cell Significance Index: 8.5800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.3425
    Cell Significance Index: 67.9800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.3106
    Cell Significance Index: 214.8400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.3067
    Cell Significance Index: 8.5700
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.2687
    Cell Significance Index: 16.1300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2563
    Cell Significance Index: 17.7300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.2389
    Cell Significance Index: 32.8100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2350
    Cell Significance Index: 44.7300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.2141
    Cell Significance Index: 16.4300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.2127
    Cell Significance Index: 14.3000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1934
    Cell Significance Index: 34.8600
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.1931
    Cell Significance Index: 5.5100
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.1678
    Cell Significance Index: 2.0000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.1640
    Cell Significance Index: 19.1100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.1426
    Cell Significance Index: 7.4100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.1348
    Cell Significance Index: 8.7000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1332
    Cell Significance Index: 6.2100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.1153
    Cell Significance Index: 14.7800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0945
    Cell Significance Index: 11.6200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0926
    Cell Significance Index: 50.5500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0706
    Cell Significance Index: 2.0400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0697
    Cell Significance Index: 6.8900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0355
    Cell Significance Index: 0.7700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0317
    Cell Significance Index: 14.0200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0269
    Cell Significance Index: 50.6900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0135
    Cell Significance Index: 8.5700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0122
    Cell Significance Index: 5.5400
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0105
    Cell Significance Index: 0.1800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0075
    Cell Significance Index: 13.8200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0054
    Cell Significance Index: 8.3100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0114
    Cell Significance Index: -15.5400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0121
    Cell Significance Index: -8.8600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0137
    Cell Significance Index: -0.4800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0146
    Cell Significance Index: -2.1300
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0169
    Cell Significance Index: -0.8800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0200
    Cell Significance Index: -14.8500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0219
    Cell Significance Index: -16.5400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.0226
    Cell Significance Index: -0.7900
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0268
    Cell Significance Index: -0.5600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0312
    Cell Significance Index: -17.5700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0315
    Cell Significance Index: -1.4300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0342
    Cell Significance Index: -5.8400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0383
    Cell Significance Index: -23.9100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0404
    Cell Significance Index: -1.1000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0423
    Cell Significance Index: -1.1300
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0479
    Cell Significance Index: -1.2600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0603
    Cell Significance Index: -17.3600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0672
    Cell Significance Index: -7.9300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0854
    Cell Significance Index: -6.0400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0868
    Cell Significance Index: -11.2200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0906
    Cell Significance Index: -9.2500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0926
    Cell Significance Index: -1.5500
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1035
    Cell Significance Index: -7.7200
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.1046
    Cell Significance Index: -2.2400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1080
    Cell Significance Index: -22.7400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1334
    Cell Significance Index: -6.2700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1341
    Cell Significance Index: -15.3600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1375
    Cell Significance Index: -7.2200
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1616
    Cell Significance Index: -3.4300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1694
    Cell Significance Index: -17.6400
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.1722
    Cell Significance Index: -2.3500
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.2029
    Cell Significance Index: -4.2100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2246
    Cell Significance Index: -17.7900
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.2425
    Cell Significance Index: -6.9500
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.2558
    Cell Significance Index: -5.9100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2562
    Cell Significance Index: -8.2100
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.2628
    Cell Significance Index: -3.8800
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.2736
    Cell Significance Index: -4.3400
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.2817
    Cell Significance Index: -5.5700
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.2939
    Cell Significance Index: -5.9000
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2964
    Cell Significance Index: -9.4400
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.3119
    Cell Significance Index: -10.2100
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.3439
    Cell Significance Index: -8.8400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.3450
    Cell Significance Index: -21.1500
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.3626
    Cell Significance Index: -6.2700
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.3993
    Cell Significance Index: -13.9900
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.4202
    Cell Significance Index: -5.2400
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: -0.4380
    Cell Significance Index: -2.7100
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.4443
    Cell Significance Index: -9.6000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** PHC1 is a polyhomeotic-like protein, a member of the polyhomeotic complex, which is characterized by its ability to interact with other proteins and regulate gene expression. PHC1 is a transcriptional regulator that binds to specific DNA sequences, influencing the expression of target genes. It is also involved in various cellular processes, including stress response, metabolism, and chromatin organization. **Pathways and Functions:** PHC1 is implicated in several cellular pathways, including: 1. **Cellular responses to stimuli**: PHC1 regulates the expression of genes involved in stress response, such as those related to oxidative stress and DNA damage. 2. **Cellular responses to stress**: PHC1 interacts with other proteins to modulate the expression of genes involved in stress response, including those related to DNA repair and repair. 3. **Cellular response to leukemia inhibitory factor**: PHC1 regulates the expression of genes involved in the response to leukemia inhibitory factor, a protein that regulates cell growth and differentiation. 4. **Cellular response to retinoic acid**: PHC1 interacts with retinoic acid receptors to regulate the expression of genes involved in cell growth and differentiation. 5. **Chromatin organization**: PHC1 regulates the structure and function of chromatin, influencing gene expression and cellular differentiation. 6. **Gene expression (transcription)**: PHC1 binds to specific DNA sequences, influencing the expression of target genes involved in various cellular processes. 7. **Intracellular signaling by second messengers**: PHC1 interacts with signaling pathways, influencing the expression of genes involved in cellular responses to stimuli. **Clinical Significance:** The PHC1 gene has been implicated in various diseases, including: 1. **Neurological disorders**: PHC1 is highly expressed in neurons and astrocytes, suggesting its involvement in neurological disorders, such as epilepsy and Alzheimer's disease. 2. **Cancer**: PHC1 is involved in the regulation of cell growth and differentiation, making it a potential target for cancer therapy. 3. **Neurodevelopmental disorders**: PHC1 is expressed in the developing brain, suggesting its involvement in neurodevelopmental disorders, such as autism and schizophrenia. In conclusion, the PHC1 gene is a critical regulator of cellular responses and metabolism, playing a significant role in various cellular processes. Its involvement in neurological disorders, cancer, and neurodevelopmental disorders highlights the importance of further research into the functions and clinical significance of PHC1. **Proteins:** The PHC1 gene encodes two proteins, PHC1_HUMAN (Polyhomeotic-like protein 1) and Q6N083_HUMAN (uncharacterized protein), which interact with other proteins to regulate gene expression and cellular processes. **Significantly expressed cells:** PHC1 is highly expressed in various cell types, including: 1. Pulmonary interstitial fibroblast 2. Caudal ganglionic eminence-derived GABAergic cortical interneuron 3. Pvalb GABAergic cortical interneuron 4. L5 extratelencephalic projecting glutamatergic cortical neuron 5. Corticothalamic-projecting glutamatergic cortical neuron 6. Neuron 7. Astrocyte of the cerebral cortex 8. L6b glutamatergic cortical neuron 9. Vip GABAergic cortical interneuron In summary, the PHC1 gene is a critical regulator of cellular responses and metabolism, playing a significant role in various cellular processes. Its involvement in neurological disorders, cancer, and neurodevelopmental disorders highlights the importance of further research into the functions and clinical significance of PHC1.

Genular Protein ID: 1028481732

Symbol: PHC1_HUMAN

Name: Polyhomeotic-like protein 1

UniProtKB Accession Codes:

P78364 D3DUV4 Q8WVM3 Q9BU63

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CORUM 1 CTD 1 ChEBI 4 ChiTaRS 1 ComplexPortal 20 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 6 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 14 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 9 RefSeq 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9121482

Title: Identification and characterization of interactions between the vertebrate polycomb-group protein BMI1 and human homologs of polyhomeotic.

PubMed ID: 9121482

DOI: 10.1128/mcb.17.4.2326

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9199346

Title: RING1 is associated with the polycomb group protein complex and acts as a transcriptional repressor.

PubMed ID: 9199346

DOI: 10.1128/mcb.17.7.4105

PubMed ID: 12167701

Title: The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans.

PubMed ID: 12167701

DOI: 10.1128/mcb.22.17.6070-6078.2002

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19636380

Title: Several distinct polycomb complexes regulate and co-localize on the INK4a tumor suppressor locus.

PubMed ID: 19636380

DOI: 10.1371/journal.pone.0006380

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21282530

Title: Interaction proteomics analysis of polycomb proteins defines distinct PRC1 Complexes in mammalian cells.

PubMed ID: 21282530

DOI: 10.1074/mcp.m110.002642

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23418308

Title: Mutation in PHC1 implicates chromatin remodeling in primary microcephaly pathogenesis.

PubMed ID: 23418308

DOI: 10.1093/hmg/ddt072

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

Sequence Information:

  • Length: 1004
  • Mass: 105534
  • Checksum: D53764F80931A938
  • Sequence:
    • METESEQNSN STNGSSSSGG SSRPQIAQMS LYERQAVQAL QALQRQPNAA QYFHQFMLQQ 
QLSNAQLHSL AAVQQATIAA SRQASSPNTS TTQQQTTTTQ ASINLATTSA AQLISRSQSV 
SSPSATTLTQ SVLLGNTTSP PLNQSQAQMY LRPQLGNLLQ VNRTLGRNVP LASQLILMPN 
GAVAAVQQEV PSAQSPGVHA DADQVQNLAV RNQQASAQGP QMQGSTQKAI PPGASPVSSL 
SQASSQALAV AQASSGATNQ SLNLSQAGGG SGNSIPGSMG PGGGGQAHGG LGQLPSSGMG 
GGSCPRKGTG VVQPLPAAQT VTVSQGSQTE AESAAAKKAE ADGSGQQNVG MNLTRTATPA 
PSQTLISSAT YTQIQPHSLI QQQQQIHLQQ KQVVIQQQIA IHHQQQFQHR QSQLLHTATH 
LQLAQQQQQQ QQQQQQQQQP QATTLTAPQP PQVPPTQQVP PSQSQQQAQT LVVQPMLQSS 
PLSLPPDAAP KPPIPIQSKP PVAPIKPPQL GAAKMSAAQQ PPPHIPVQVV GTRQPGTAQA 
QALGLAQLAA AVPTSRGMPG TVQSGQAHLA SSPPSSQAPG ALQECPPTLA PGMTLAPVQG 
TAHVVKGGAT TSSPVVAQVP AAFYMQSVHL PGKPQTLAVK RKADSEEERD DVSTLGSMLP 
AKASPVAESP KVMDEKSSLG EKAESVANVN ANTPSSELVA LTPAPSVPPP TLAMVSRQMG 
DSKPPQAIVK PQILTHIIEG FVIQEGAEPF PVGCSQLLKE SEKPLQTGLP TGLTENQSGG 
PLGVDSPSAE LDKKANLLKC EYCGKYAPAE QFRGSKRFCS MTCAKRYNVS CSHQFRLKRK 
KMKEFQEANY ARVRRRGPRR SSSDIARAKI QGKCHRGQED SSRGSDNSSY DEALSPTSPG 
PLSVRAGHGE RDLGNPNTAP PTPELHGINP VFLSSNPSRW SVEEVYEFIA SLQGCQEIAE 
EFRSQEIDGQ ALLLLKEEHL MSAMNIKLGP ALKICAKINV LKET

Genular Protein ID: 4115119100

Symbol: Q6N083_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6N083

Database IDs:

ARBA 6 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 6 Gene3D 2 InterPro 5 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 4 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 3 RefSeq 1 SAM 1 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 610
  • Mass: 64811
  • Checksum: AF71340B2028DC98
  • Sequence:
    • MQGSTQKAIP PGASPVSSLS QASSQALAVA QASSGATNQS LNLSQAGGGS GNSIPGSMGP 
GGGGQAHGGL GQLPSSGMGG GSCPRKGTGV VQPLPAAQTV TVSQGSQTEA ESAAAKKAEA 
DGSGQQNVGM NLTRTATPAP SQTLISSATY TQIQPHSLIQ QQQQIHLQQK QVVIQQQIAI 
HHQQQFQHRQ SQLLHTAAHL QLAQQQQQQQ QQQQQQQQPQ ATTLTAPQPP QVPPTQQGKP 
QTLAVKRKAD SEEERDDVST LGSMLPAKAS PVAESPKVMD EKSSLGEKAE SVANVNANAP 
SSELVALTPA PSVPPPTLAM VSRQMGDSKP PQAIVKPQIL THIIEGFVIQ EGAEPFPVGC 
SQLLKESEKP LQTGLPTGLT ENQSGGPLGV DSPSAELDKK ANLLKCEYCG KYAPAEQFRG 
SKRFCSMTCA KRYNVSCSHQ FRLKRKKMKE FQEANYARVR RRGPRRSSSD IARAKIQGKC 
HRGQEDSSRG SDNSSYDEAL SPTSPGPLSV RAGHGERDLG NPNTAPPTPE LHGINPVFLS 
SNPSRWSVEE VYEFIASLQG CQEIAEEFRS QEIDGQALLL LKEEHLMSAM NIKLGPALKI 
CAKINVLKET

Genular Protein ID: 415449371

Symbol: Q6GMQ3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6GMQ3

Database IDs:

ARBA 6 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 2 InterPro 5 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 4 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 RefSeq 1 SAM 1 SMART 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 957
  • Mass: 100199
  • Checksum: 192440A4BBAFA37D
  • Sequence:
    • METESEQNSN STNGSSSSGG SSRPQIAQMS LYERQAVQAT IAASRQASSP NTSTTQQQTT 
TTQASINLAT TSAAQLISRS QSVSSPSATT LTQSVLLGNT TSPPLNQSQA QMYLRVNRTL 
GRNVPLASQL ILMPNGAVAA VQQEVPSAQS PGVHADADQV QNLAVRNQQA SAQGPQMQGS 
TQKAIPPGAS PVSSLSQASS QALAVAQASS GATNQSLNLS QAGGGSGNSI PGSMGPGGGG 
QAHGGLGQLP SSGMGGGSCP RKGTGVVQPL PAAQTVTVSQ GSQTEAESAA AKKAEADGSG 
QQNVGMNLTR TATPAPSQTL ISSATYTQIQ PHSLIQQQQQ IHLQQKQVVI QQQIAIHHQQ 
QFQHRQSQLL HTATHLQLAQ QQQQQQQQQQ QQPQATTLTA PQPPQVPPTQ QVPPSQSQQQ 
AQTLVVQPML QSSPLSLPPD AAPKPPIPIQ SKPPVAPIKP PQLGAAKMSA AQQPPPHIPV 
QVVGTRQPGT AQAQALGLAQ LAAAVPTSRG MPGTVQSGQA HLASSPPSSQ APGALQECPP 
TLAPGMTLAP VQGTAHVVKG GATTSSPVVA QVPAAFYMQS VHLPGKPQTL AVKRKADSEE 
ERDDVSTLGS MLPAKASPVA ESPKVMDEKS SLGEKAESVA NVNANTPSSE LVALTPAPSV 
PPPTLAMVSR QMGDSKPPQA IVKPQILTHI IEGFVIQEGA EPFPVGCSQL LKESEKPLQT 
GLPTGLTENQ SGGSLGVDSP SAELDKKANL LKCEYCGKYA PAEQFRGSKR FCSMTCAKRY 
NVSCSHQFRL KRKKMKEFQE ANYARVRRRG PRRSSSDIAR AKIQGKCHRG QEDSSRGSDN 
SSYDEALSPT SPGPLSVRAG HGERDLGNPN TAPPTPELHG INPVFLSSNP SRWSVEEVYE 
FIASLQGCQE IAEEFRSQEI DGQALLLLKE EHLMSAMNIK LGPALKICAK INVLKET

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.