Details for: PHC1
Associated with
Cells (max top 100)
(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: pulmonary interstitial fibroblast (CL0002241)
Fold Change: 1.33
Marker Score: 1067 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.3
Marker Score: 5035 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.29
Marker Score: 47576 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.28
Marker Score: 1983 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.28
Marker Score: 12157 - Cell Name: neuron (CL0000540)
Fold Change: 1.25
Marker Score: 5098 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 1.17
Marker Score: 23326 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 1.17
Marker Score: 25019 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.17
Marker Score: 10035 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 1.12
Marker Score: 42445 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.08
Marker Score: 66431 - Cell Name: primordial germ cell (CL0000670)
Fold Change: 1.07
Marker Score: 1346.5 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 1.06
Marker Score: 8130 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 1.06
Marker Score: 4389 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71765 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 47990 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 0.99
Marker Score: 14755 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 0.98
Marker Score: 10128 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30402 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 0.95
Marker Score: 8971 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2407 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.94
Marker Score: 485 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.93
Marker Score: 440 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2722 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.88
Marker Score: 5046 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5289 - Cell Name: male germ cell (CL0000015)
Fold Change: 0.86
Marker Score: 249 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.86
Marker Score: 308 - Cell Name: Unknown (CL0002371)
Fold Change: 0.83
Marker Score: 882 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 0.82
Marker Score: 1384 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.78
Marker Score: 12274 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.76
Marker Score: 1228 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.75
Marker Score: 7544 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.74
Marker Score: 1624 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.74
Marker Score: 565 - Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 0.73
Marker Score: 1986 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.73
Marker Score: 376 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.72
Marker Score: 288 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 0.71
Marker Score: 817 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.71
Marker Score: 2967.5 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 0.69
Marker Score: 403 - Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
Fold Change: 0.68
Marker Score: 5926 - Cell Name: brush cell (CL0002204)
Fold Change: 0.67
Marker Score: 611 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.66
Marker Score: 170 - Cell Name: Sertoli cell (CL0000216)
Fold Change: 0.64
Marker Score: 3819.5 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 0.64
Marker Score: 2951 - Cell Name: oogonial cell (CL0000024)
Fold Change: 0.63
Marker Score: 907 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.6
Marker Score: 622 - Cell Name: mesenchymal stem cell (CL0000134)
Fold Change: 0.58
Marker Score: 896 - Cell Name: kidney collecting duct principal cell (CL1001431)
Fold Change: 0.57
Marker Score: 1429 - Cell Name: renal principal cell (CL0005009)
Fold Change: 0.56
Marker Score: 434 - Cell Name: mesangial cell (CL0000650)
Fold Change: 0.56
Marker Score: 671 - Cell Name: keratocyte (CL0002363)
Fold Change: 0.55
Marker Score: 126 - Cell Name: astrocyte (CL0000127)
Fold Change: 0.55
Marker Score: 473 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.54
Marker Score: 427 - Cell Name: parietal epithelial cell (CL1000452)
Fold Change: 0.53
Marker Score: 194 - Cell Name: peripheral nervous system neuron (CL2000032)
Fold Change: 0.53
Marker Score: 594 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.52
Marker Score: 2194.5 - Cell Name: neural crest cell (CL0011012)
Fold Change: 0.52
Marker Score: 558 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 0.51
Marker Score: 555 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 0.5
Marker Score: 1434 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 0.5
Marker Score: 3240 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.49
Marker Score: 190 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.49
Marker Score: 144 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 0.49
Marker Score: 1820 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 0.48
Marker Score: 319 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 0.48
Marker Score: 517 - Cell Name: smooth muscle cell of large intestine (CL1000279)
Fold Change: 0.48
Marker Score: 183 - Cell Name: ependymal cell (CL0000065)
Fold Change: 0.48
Marker Score: 168 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 0.47
Marker Score: 265 - Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
Fold Change: 0.47
Marker Score: 501 - Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
Fold Change: 0.47
Marker Score: 1266 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: 0.47
Marker Score: 495 - Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
Fold Change: 0.47
Marker Score: 662 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.47
Marker Score: 1063 - Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 0.47
Marker Score: 1097 - Cell Name: migratory enteric neural crest cell (CL0002607)
Fold Change: 0.47
Marker Score: 438 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 0.46
Marker Score: 443 - Cell Name: naive regulatory T cell (CL0002677)
Fold Change: 0.46
Marker Score: 139 - Cell Name: Leydig cell (CL0000178)
Fold Change: 0.46
Marker Score: 493 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.45
Marker Score: 15358 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.45
Marker Score: 299 - Cell Name: type EC enteroendocrine cell (CL0000577)
Fold Change: 0.45
Marker Score: 422 - Cell Name: oocyte (CL0000023)
Fold Change: 0.44
Marker Score: 110 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.44
Marker Score: 301 - Cell Name: ciliated cell (CL0000064)
Fold Change: 0.44
Marker Score: 1521 - Cell Name: ciliated epithelial cell (CL0000067)
Fold Change: 0.43
Marker Score: 196 - Cell Name: DN3 thymocyte (CL0000807)
Fold Change: 0.43
Marker Score: 214 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.43
Marker Score: 257 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 0.43
Marker Score: 822 - Cell Name: nephron tubule epithelial cell (CL1000494)
Fold Change: 0.42
Marker Score: 99 - Cell Name: mesodermal cell (CL0000222)
Fold Change: 0.42
Marker Score: 5566 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 0.42
Marker Score: 133 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 0.42
Marker Score: 176 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 0.42
Marker Score: 878 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.42
Marker Score: 2515 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 0.42
Marker Score: 591 - Cell Name: lung ciliated cell (CL1000271)
Fold Change: 0.42
Marker Score: 198 - Cell Name: respiratory epithelial cell (CL0002368)
Fold Change: 0.41
Marker Score: 228 - Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
Fold Change: 0.41
Marker Score: 420
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Other Information
Genular Protein ID: 1028481732
Symbol: PHC1_HUMAN
Name: Polyhomeotic-like protein 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9121482
Title: Identification and characterization of interactions between the vertebrate polycomb-group protein BMI1 and human homologs of polyhomeotic.
PubMed ID: 9121482
PubMed ID: 16541075
Title: The finished DNA sequence of human chromosome 12.
PubMed ID: 16541075
DOI: 10.1038/nature04569
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9199346
Title: RING1 is associated with the polycomb group protein complex and acts as a transcriptional repressor.
PubMed ID: 9199346
PubMed ID: 12167701
Title: The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans.
PubMed ID: 12167701
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19636380
Title: Several distinct polycomb complexes regulate and co-localize on the INK4a tumor suppressor locus.
PubMed ID: 19636380
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 21282530
Title: Interaction proteomics analysis of polycomb proteins defines distinct PRC1 Complexes in mammalian cells.
PubMed ID: 21282530
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23418308
Title: Mutation in PHC1 implicates chromatin remodeling in primary microcephaly pathogenesis.
PubMed ID: 23418308
DOI: 10.1093/hmg/ddt072
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
Sequence Information:
- Length: 1004
- Mass: 105534
- Checksum: D53764F80931A938
- Sequence:
METESEQNSN STNGSSSSGG SSRPQIAQMS LYERQAVQAL QALQRQPNAA QYFHQFMLQQ QLSNAQLHSL AAVQQATIAA SRQASSPNTS TTQQQTTTTQ ASINLATTSA AQLISRSQSV SSPSATTLTQ SVLLGNTTSP PLNQSQAQMY LRPQLGNLLQ VNRTLGRNVP LASQLILMPN GAVAAVQQEV PSAQSPGVHA DADQVQNLAV RNQQASAQGP QMQGSTQKAI PPGASPVSSL SQASSQALAV AQASSGATNQ SLNLSQAGGG SGNSIPGSMG PGGGGQAHGG LGQLPSSGMG GGSCPRKGTG VVQPLPAAQT VTVSQGSQTE AESAAAKKAE ADGSGQQNVG MNLTRTATPA PSQTLISSAT YTQIQPHSLI QQQQQIHLQQ KQVVIQQQIA IHHQQQFQHR QSQLLHTATH LQLAQQQQQQ QQQQQQQQQP QATTLTAPQP PQVPPTQQVP PSQSQQQAQT LVVQPMLQSS PLSLPPDAAP KPPIPIQSKP PVAPIKPPQL GAAKMSAAQQ PPPHIPVQVV GTRQPGTAQA QALGLAQLAA AVPTSRGMPG TVQSGQAHLA SSPPSSQAPG ALQECPPTLA PGMTLAPVQG TAHVVKGGAT TSSPVVAQVP AAFYMQSVHL PGKPQTLAVK RKADSEEERD DVSTLGSMLP AKASPVAESP KVMDEKSSLG EKAESVANVN ANTPSSELVA LTPAPSVPPP TLAMVSRQMG DSKPPQAIVK PQILTHIIEG FVIQEGAEPF PVGCSQLLKE SEKPLQTGLP TGLTENQSGG PLGVDSPSAE LDKKANLLKC EYCGKYAPAE QFRGSKRFCS MTCAKRYNVS CSHQFRLKRK KMKEFQEANY ARVRRRGPRR SSSDIARAKI QGKCHRGQED SSRGSDNSSY DEALSPTSPG PLSVRAGHGE RDLGNPNTAP PTPELHGINP VFLSSNPSRW SVEEVYEFIA SLQGCQEIAE EFRSQEIDGQ ALLLLKEEHL MSAMNIKLGP ALKICAKINV LKET
Genular Protein ID: 4115119100
Symbol: Q6N083_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 610
- Mass: 64811
- Checksum: AF71340B2028DC98
- Sequence:
MQGSTQKAIP PGASPVSSLS QASSQALAVA QASSGATNQS LNLSQAGGGS GNSIPGSMGP GGGGQAHGGL GQLPSSGMGG GSCPRKGTGV VQPLPAAQTV TVSQGSQTEA ESAAAKKAEA DGSGQQNVGM NLTRTATPAP SQTLISSATY TQIQPHSLIQ QQQQIHLQQK QVVIQQQIAI HHQQQFQHRQ SQLLHTAAHL QLAQQQQQQQ QQQQQQQQPQ ATTLTAPQPP QVPPTQQGKP QTLAVKRKAD SEEERDDVST LGSMLPAKAS PVAESPKVMD EKSSLGEKAE SVANVNANAP SSELVALTPA PSVPPPTLAM VSRQMGDSKP PQAIVKPQIL THIIEGFVIQ EGAEPFPVGC SQLLKESEKP LQTGLPTGLT ENQSGGPLGV DSPSAELDKK ANLLKCEYCG KYAPAEQFRG SKRFCSMTCA KRYNVSCSHQ FRLKRKKMKE FQEANYARVR RRGPRRSSSD IARAKIQGKC HRGQEDSSRG SDNSSYDEAL SPTSPGPLSV RAGHGERDLG NPNTAPPTPE LHGINPVFLS SNPSRWSVEE VYEFIASLQG CQEIAEEFRS QEIDGQALLL LKEEHLMSAM NIKLGPALKI CAKINVLKET
Genular Protein ID: 415449371
Symbol: Q6GMQ3_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 957
- Mass: 100199
- Checksum: 192440A4BBAFA37D
- Sequence:
METESEQNSN STNGSSSSGG SSRPQIAQMS LYERQAVQAT IAASRQASSP NTSTTQQQTT TTQASINLAT TSAAQLISRS QSVSSPSATT LTQSVLLGNT TSPPLNQSQA QMYLRVNRTL GRNVPLASQL ILMPNGAVAA VQQEVPSAQS PGVHADADQV QNLAVRNQQA SAQGPQMQGS TQKAIPPGAS PVSSLSQASS QALAVAQASS GATNQSLNLS QAGGGSGNSI PGSMGPGGGG QAHGGLGQLP SSGMGGGSCP RKGTGVVQPL PAAQTVTVSQ GSQTEAESAA AKKAEADGSG QQNVGMNLTR TATPAPSQTL ISSATYTQIQ PHSLIQQQQQ IHLQQKQVVI QQQIAIHHQQ QFQHRQSQLL HTATHLQLAQ QQQQQQQQQQ QQPQATTLTA PQPPQVPPTQ QVPPSQSQQQ AQTLVVQPML QSSPLSLPPD AAPKPPIPIQ SKPPVAPIKP PQLGAAKMSA AQQPPPHIPV QVVGTRQPGT AQAQALGLAQ LAAAVPTSRG MPGTVQSGQA HLASSPPSSQ APGALQECPP TLAPGMTLAP VQGTAHVVKG GATTSSPVVA QVPAAFYMQS VHLPGKPQTL AVKRKADSEE ERDDVSTLGS MLPAKASPVA ESPKVMDEKS SLGEKAESVA NVNANTPSSE LVALTPAPSV PPPTLAMVSR QMGDSKPPQA IVKPQILTHI IEGFVIQEGA EPFPVGCSQL LKESEKPLQT GLPTGLTENQ SGGSLGVDSP SAELDKKANL LKCEYCGKYA PAEQFRGSKR FCSMTCAKRY NVSCSHQFRL KRKKMKEFQE ANYARVRRRG PRRSSSDIAR AKIQGKCHRG QEDSSRGSDN SSYDEALSPT SPGPLSVRAG HGERDLGNPN TAPPTPELHG INPVFLSSNP SRWSVEEVYE FIASLQGCQE IAEEFRSQEI DGQALLLLKE EHLMSAMNIK LGPALKICAK INVLKET
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.