Details for: EPHX2

Gene ID: 2053

Symbol: EPHX2

Ensembl ID: ENSG00000120915

Description: epoxide hydrolase 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 121.1223
    Cell Significance Index: -18.8400
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 72.3457
    Cell Significance Index: -18.3500
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 41.9171
    Cell Significance Index: -19.7900
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 29.6264
    Cell Significance Index: -19.8800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 15.2885
    Cell Significance Index: -18.8500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 6.4654
    Cell Significance Index: -17.3200
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 4.8149
    Cell Significance Index: -19.0000
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 4.2260
    Cell Significance Index: -12.9800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 2.6142
    Cell Significance Index: 75.3200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 2.0948
    Cell Significance Index: 56.1300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 2.0855
    Cell Significance Index: 94.5300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.9738
    Cell Significance Index: 391.7000
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 1.7823
    Cell Significance Index: 14.2300
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.6931
    Cell Significance Index: 23.1000
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.4731
    Cell Significance Index: 24.8200
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.3967
    Cell Significance Index: 1261.1300
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 1.2273
    Cell Significance Index: 18.3900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.0753
    Cell Significance Index: 30.0500
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.8735
    Cell Significance Index: 95.0200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.6268
    Cell Significance Index: 48.1000
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.6202
    Cell Significance Index: 16.8800
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: 0.6166
    Cell Significance Index: 6.2200
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.5321
    Cell Significance Index: 6.8200
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 0.5015
    Cell Significance Index: 14.7700
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 0.4507
    Cell Significance Index: 7.2300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.4320
    Cell Significance Index: 20.1400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.4198
    Cell Significance Index: 8.9400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.3829
    Cell Significance Index: 49.0800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.3693
    Cell Significance Index: 19.3900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.3575
    Cell Significance Index: 11.4500
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.3376
    Cell Significance Index: 7.8000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.3176
    Cell Significance Index: 41.0400
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 0.3168
    Cell Significance Index: 1.9600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.2632
    Cell Significance Index: 13.6700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.2513
    Cell Significance Index: 34.5200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.2311
    Cell Significance Index: 26.9300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.2280
    Cell Significance Index: 8.0100
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.2262
    Cell Significance Index: 2.8100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2218
    Cell Significance Index: 21.9400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.2163
    Cell Significance Index: 16.1200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.1992
    Cell Significance Index: 11.1800
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 0.1981
    Cell Significance Index: 2.0500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1980
    Cell Significance Index: 35.6900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.1854
    Cell Significance Index: 11.6900
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.1784
    Cell Significance Index: 2.5400
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.1720
    Cell Significance Index: 3.6000
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1572
    Cell Significance Index: 69.4900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.1425
    Cell Significance Index: 104.4800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1338
    Cell Significance Index: 25.4600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.1289
    Cell Significance Index: 22.0200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.1252
    Cell Significance Index: 170.1700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1217
    Cell Significance Index: 43.6700
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.1206
    Cell Significance Index: 1.7800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: 0.1179
    Cell Significance Index: 9.3400
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.1007
    Cell Significance Index: 1.2000
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.0991
    Cell Significance Index: 3.4400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0822
    Cell Significance Index: 10.1100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0767
    Cell Significance Index: 15.3900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0599
    Cell Significance Index: 112.8200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0582
    Cell Significance Index: 40.2600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0563
    Cell Significance Index: 3.9800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0404
    Cell Significance Index: 25.6600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0366
    Cell Significance Index: 56.4200
  • Cell Name: colonocyte (CL1000347)
    Fold Change: 0.0356
    Cell Significance Index: 0.2200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0307
    Cell Significance Index: 56.5400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0304
    Cell Significance Index: 16.6100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0300
    Cell Significance Index: 13.6100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0037
    Cell Significance Index: -2.7200
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.0097
    Cell Significance Index: -1.5900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0108
    Cell Significance Index: -6.7600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0131
    Cell Significance Index: -1.9000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0138
    Cell Significance Index: -10.4600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0188
    Cell Significance Index: -10.6000
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0230
    Cell Significance Index: -0.3900
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0270
    Cell Significance Index: -1.3700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0320
    Cell Significance Index: -6.7300
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0367
    Cell Significance Index: -3.7500
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0413
    Cell Significance Index: -0.6100
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0475
    Cell Significance Index: -1.2500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0510
    Cell Significance Index: -14.6700
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.0541
    Cell Significance Index: -0.5600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0595
    Cell Significance Index: -1.2900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0612
    Cell Significance Index: -7.0100
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: -0.0876
    Cell Significance Index: -0.6700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1181
    Cell Significance Index: -5.5500
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.1303
    Cell Significance Index: -2.7900
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.1359
    Cell Significance Index: -1.1600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1388
    Cell Significance Index: -14.4500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1430
    Cell Significance Index: -16.8600
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.1473
    Cell Significance Index: -16.8100
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.1743
    Cell Significance Index: -4.4800
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1837
    Cell Significance Index: -11.2900
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: -0.1976
    Cell Significance Index: -2.1000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.2034
    Cell Significance Index: -12.4700
  • Cell Name: enterocyte (CL0000584)
    Fold Change: -0.2112
    Cell Significance Index: -1.3100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.2388
    Cell Significance Index: -5.9700
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.2480
    Cell Significance Index: -3.9400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2765
    Cell Significance Index: -18.5900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.2789
    Cell Significance Index: -14.5300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.3083
    Cell Significance Index: -19.8900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** EPHX2 is a cytosolic epoxide hydrolase that exhibits epoxide hydrolase activity, dephosphorylation activity, and phosphatase activity. It is a member of the epoxide hydrolase family, which is characterized by its ability to hydrolyze epoxides into diols. EPHX2 is also known for its ability to bind magnesium ions and regulate the activity of various enzymes involved in lipid metabolism. **Pathways and Functions:** EPHX2 is involved in several key metabolic pathways, including: 1. **Cholesterol Homeostasis:** EPHX2 hydrolyzes cholesterol epoxides, which are toxic to cells, into cholesteryl esters. This process helps maintain cholesterol homeostasis and prevents lipid peroxidation. 2. **Fatty Acid Metabolism:** EPHX2 regulates the metabolism of fatty acids by hydrolyzing epoxides, which are intermediate products of fatty acid oxidation. This helps maintain the balance of fatty acid metabolism and prevents lipid peroxidation. 3. **Arachidonic Acid Metabolism:** EPHX2 is involved in the hydrolysis of arachidonic acid epoxides, which are precursors to prostaglandins and leukotrienes. This process helps regulate inflammation and immune responses. 4. **Epoxide Metabolism:** EPHX2 is a key enzyme in the metabolism of epoxides, which are toxic compounds that can cause cellular damage. EPHX2 hydrolyzes epoxides into diols, which are less toxic and can be further metabolized by other enzymes. **Clinical Significance:** Dysregulation of EPHX2 has been implicated in various diseases, including: 1. **Cancer:** EPHX2 has been shown to be overexpressed in several types of cancer, including breast, lung, and colon cancer. This overexpression is associated with increased resistance to chemotherapy and poor prognosis. 2. **Neurological Disorders:** EPHX2 has been implicated in the pathogenesis of neurological disorders, including Alzheimer's disease and Parkinson's disease. Dysregulation of EPHX2 has been shown to contribute to the accumulation of toxic epoxides in the brain. 3. **Metabolic Disorders:** EPHX2 has been shown to play a role in regulating glucose and lipid metabolism. Dysregulation of EPHX2 has been implicated in the development of metabolic disorders, including insulin resistance and type 2 diabetes. In conclusion, EPHX2 is a crucial enzyme that plays a pivotal role in maintaining cellular and physiological homeostasis. Its dysregulation has been implicated in various diseases, highlighting the importance of understanding its functions and mechanisms of action. Further research is needed to fully elucidate the role of EPHX2 in human health and disease.

Genular Protein ID: 4196678910

Symbol: HYES_HUMAN

Name: Cytosolic epoxide hydrolase 2

UniProtKB Accession Codes:

P34913 B2Z3B1 B3KTU8 B3KUA0 G3V134 J3KPH7 Q16764 Q9HBJ1 Q9HBJ2

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 2 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CTD 1 ChEBI 89 ChEMBL 1 ChiTaRS 1 DEPOD 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 9 DrugCentral 1 EC 2 EMBL 30 ESTHER 1 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 20 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MEROPS 1 MIM 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 NCBIfam 2 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 100 PDBsum 100 PIR 1 PRINTS 2 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 3 RefSeq 4 Rhea 48 SABIO-RK 1 SFLD 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissLipids 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 2 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8342951

Title: cDNA cloning and expression of a soluble epoxide hydrolase from human liver.

PubMed ID: 8342951

DOI: 10.1006/abbi.1993.1411

PubMed ID: 8619856

Title: Structural characterization of the human soluble epoxide hydrolase gene (EPHX2).

PubMed ID: 8619856

DOI: 10.1006/bbrc.1996.0596

PubMed ID: 10862610

Title: Identification and functional characterization of human soluble epoxide hydrolase genetic polymorphisms.

PubMed ID: 10862610

DOI: 10.1074/jbc.m001153200

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12869654

Title: Polymorphisms in human soluble epoxide hydrolase.

PubMed ID: 12869654

DOI: 10.1124/mol.64.2.482

PubMed ID: 12574508

Title: The N-terminal domain of mammalian soluble epoxide hydrolase is a phosphatase.

PubMed ID: 12574508

DOI: 10.1073/pnas.0437829100

PubMed ID: 12574510

Title: The soluble epoxide hydrolase encoded by EPXH2 is a bifunctional enzyme with novel lipid phosphate phosphatase activity.

PubMed ID: 12574510

DOI: 10.1073/pnas.0437724100

PubMed ID: 15196990

Title: Polymorphisms in human soluble epoxide hydrolase: effects on enzyme activity, enzyme stability, and quaternary structure.

PubMed ID: 15196990

DOI: 10.1016/j.abb.2004.05.003

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21164107

Title: Redox regulation of soluble epoxide hydrolase by 15-deoxy-delta-prostaglandin J2 controls coronary hypoxic vasodilation.

PubMed ID: 21164107

DOI: 10.1161/circresaha.110.235879

PubMed ID: 21217101

Title: Mammalian soluble epoxide hydrolase is identical to liver hepoxilin hydrolase.

PubMed ID: 21217101

DOI: 10.1194/jlr.m009639

PubMed ID: 22387545

Title: Role of soluble epoxide hydrolase phosphatase activity in the metabolism of lysophosphatidic acids.

PubMed ID: 22387545

DOI: 10.1016/j.bbrc.2012.02.108

PubMed ID: 22217705

Title: Lysophosphatidic acids are new substrates for the phosphatase domain of soluble epoxide hydrolase.

PubMed ID: 22217705

DOI: 10.1194/jlr.m022319

PubMed ID: 22798687

Title: EH3 (ABHD9): the first member of a new epoxide hydrolase family with high activity for fatty acid epoxides.

PubMed ID: 22798687

DOI: 10.1194/jlr.m024448

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 15096040

Title: Structure of human epoxide hydrolase reveals mechanistic inferences on bifunctional catalysis in epoxide and phosphate ester hydrolysis.

PubMed ID: 15096040

DOI: 10.1021/bi036189j

PubMed ID: 16322563

Title: Human soluble epoxide hydrolase: structural basis of inhibition by 4-(3-cyclohexylureido)-carboxylic acids.

PubMed ID: 16322563

DOI: 10.1110/ps.051720206

PubMed ID: 19746975

Title: Structure-based optimization of arylamides as inhibitors of soluble epoxide hydrolase.

PubMed ID: 19746975

DOI: 10.1021/jm9005302

PubMed ID: 19969453

Title: Optimization of piperidyl-ureas as inhibitors of soluble epoxide hydrolase.

PubMed ID: 19969453

DOI: 10.1016/j.bmcl.2009.11.091

PubMed ID: 20934334

Title: Substituted pyrazoles as novel sEH antagonist: investigation of key binding interactions within the catalytic domain.

PubMed ID: 20934334

DOI: 10.1016/j.bmcl.2010.09.095

Sequence Information:

  • Length: 555
  • Mass: 62616
  • Checksum: 1B5ACE7F80F9A26C
  • Sequence:
    • MTLRAAVFDL DGVLALPAVF GVLGRTEEAL ALPRGLLNDA FQKGGPEGAT TRLMKGEITL 
SQWIPLMEEN CRKCSETAKV CLPKNFSIKE IFDKAISARK INRPMLQAAL MLRKKGFTTA 
ILTNTWLDDR AERDGLAQLM CELKMHFDFL IESCQVGMVK PEPQIYKFLL DTLKASPSEV 
VFLDDIGANL KPARDLGMVT ILVQDTDTAL KELEKVTGIQ LLNTPAPLPT SCNPSDMSHG 
YVTVKPRVRL HFVELGSGPA VCLCHGFPES WYSWRYQIPA LAQAGYRVLA MDMKGYGESS 
APPEIEEYCM EVLCKEMVTF LDKLGLSQAV FIGHDWGGML VWYMALFYPE RVRAVASLNT 
PFIPANPNMS PLESIKANPV FDYQLYFQEP GVAEAELEQN LSRTFKSLFR ASDESVLSMH 
KVCEAGGLFV NSPEEPSLSR MVTEEEIQFY VQQFKKSGFR GPLNWYRNME RNWKWACKSL 
GRKILIPALM VTAEKDFVLV PQMSQHMEDW IPHLKRGHIE DCGHWTQMDK PTEVNQILIK 
WLDSDARNPP VVSKM

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.