Details for: ERCC4

Gene ID: 2072

Symbol: ERCC4

Ensembl ID: ENSG00000175595

Description: ERCC excision repair 4, endonuclease catalytic subunit

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: germ cell (CL0000586)
    Fold Change: 1.6
    Marker Score: 2794
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.47
    Marker Score: 168679
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.23
    Marker Score: 19269
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.06
    Marker Score: 1631
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71742
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47966
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30399
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 0.97
    Marker Score: 778
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2403
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.94
    Marker Score: 483
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 0.94
    Marker Score: 8037
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.93
    Marker Score: 439
  • Cell Name: gut endothelial cell (CL0000131)
    Fold Change: 0.91
    Marker Score: 326
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2717
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 0.88
    Marker Score: 1787
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5287
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.87
    Marker Score: 4956
  • Cell Name: neuron (CL0000540)
    Fold Change: 0.87
    Marker Score: 3527
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.86
    Marker Score: 308
  • Cell Name: oogonial cell (CL0000024)
    Fold Change: 0.85
    Marker Score: 1228
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.84
    Marker Score: 51634
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 0.82
    Marker Score: 30360
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.81
    Marker Score: 8397
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.81
    Marker Score: 4841
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 0.8
    Marker Score: 7637
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 0.79
    Marker Score: 1870
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: 0.79
    Marker Score: 6834
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 0.78
    Marker Score: 717
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1262
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.77
    Marker Score: 368
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.75
    Marker Score: 572.5
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.75
    Marker Score: 300
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.74
    Marker Score: 446
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 0.73
    Marker Score: 6868
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.72
    Marker Score: 375
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 0.72
    Marker Score: 224
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.7
    Marker Score: 2938
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.67
    Marker Score: 611
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.66
    Marker Score: 170
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.66
    Marker Score: 2558
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.66
    Marker Score: 212
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 0.65
    Marker Score: 13874
  • Cell Name: male germ cell (CL0000015)
    Fold Change: 0.64
    Marker Score: 185
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 0.63
    Marker Score: 1722
  • Cell Name: multi-ciliated epithelial cell (CL0005012)
    Fold Change: 0.62
    Marker Score: 1176
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.62
    Marker Score: 1306
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 0.62
    Marker Score: 23375
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 0.6
    Marker Score: 650
  • Cell Name: oocyte (CL0000023)
    Fold Change: 0.6
    Marker Score: 148
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 0.6
    Marker Score: 8919
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 0.59
    Marker Score: 11746
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 0.58
    Marker Score: 1989
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 0.58
    Marker Score: 2392
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 0.57
    Marker Score: 689
  • Cell Name: primordial germ cell (CL0000670)
    Fold Change: 0.56
    Marker Score: 706.5
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: 0.56
    Marker Score: 195
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.55
    Marker Score: 6171
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.54
    Marker Score: 431
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 0.54
    Marker Score: 2000
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.54
    Marker Score: 357
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 0.52
    Marker Score: 453
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.52
    Marker Score: 2043
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.52
    Marker Score: 5229
  • Cell Name: neural cell (CL0002319)
    Fold Change: 0.52
    Marker Score: 249
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 0.51
    Marker Score: 215
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 0.51
    Marker Score: 2373
  • Cell Name: ciliated epithelial cell (CL0000067)
    Fold Change: 0.51
    Marker Score: 232
  • Cell Name: lung ciliated cell (CL1000271)
    Fold Change: 0.51
    Marker Score: 240
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.5
    Marker Score: 322.5
  • Cell Name: neuronal receptor cell (CL0000006)
    Fold Change: 0.5
    Marker Score: 221
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.5
    Marker Score: 1133
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.49
    Marker Score: 17091
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.49
    Marker Score: 512
  • Cell Name: peripheral nervous system neuron (CL2000032)
    Fold Change: 0.49
    Marker Score: 553
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 0.49
    Marker Score: 521
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 0.49
    Marker Score: 2918
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 0.49
    Marker Score: 3769
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.49
    Marker Score: 130
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 0.49
    Marker Score: 204
  • Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
    Fold Change: 0.48
    Marker Score: 163
  • Cell Name: Unknown (CL0002371)
    Fold Change: 0.48
    Marker Score: 515
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: 0.48
    Marker Score: 139
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: 0.48
    Marker Score: 1860
  • Cell Name: secretory cell (CL0000151)
    Fold Change: 0.48
    Marker Score: 870
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.47
    Marker Score: 139
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 0.46
    Marker Score: 310
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.46
    Marker Score: 189
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: 0.45
    Marker Score: 340
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 0.45
    Marker Score: 3364
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: 0.45
    Marker Score: 183
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 0.45
    Marker Score: 305
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 0.45
    Marker Score: 141
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 0.44
    Marker Score: 1819
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: 0.44
    Marker Score: 252
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 0.44
    Marker Score: 115
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 0.44
    Marker Score: 232
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: 0.44
    Marker Score: 424
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.43
    Marker Score: 737
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 0.43
    Marker Score: 904
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 0.43
    Marker Score: 1834

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Other Information

**Key characteristics:** * ERCC4 is a member of the ERCC family of DNA repair enzymes, which are responsible for repairing DNA damage. * ERCC4 is a single-stranded endonuclease that is capable of repairing a variety of DNA lesions, including single-nucleotide and double-stranded breaks. * ERCC4 is a highly conserved protein that is found in all eukaryotes. **Pathways and functions:** * ERCC4 is involved in several important cellular processes, including DNA repair, cell cycle regulation, and development. * ERCC4 is essential for the repair of DNA damage caused by ionizing radiation and chemicals. * In the context of cancer, ERCC4 mutations can lead to the accumulation of DNA damage, which can contribute to the development of tumors. **Clinical significance:** * Mutations in ERCC4 have been linked to several human cancers, including breast cancer, lung cancer, and colon cancer. * Inhibition of ERCC4 has been shown to be a promising strategy for treating cancer cells. * Development of drugs that target ERCC4 is an active area of research.

Genular Protein ID: 2802708318

Symbol: XPF_HUMAN

Name: DNA repair endonuclease XPF

UniProtKB Accession Codes:

Q92889 A5PKV6 A8K111 O00140 Q8TD83

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CORUM 1 CTD 1 ChEBI 1 ChEMBL 1 ComplexPortal 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 6 EMDB 2 EPD 1 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 29 Gene3D 2 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 8 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OpenTargets 1 Orphanet 4 OrthoDB 1 PANTHER 2 PDB 13 PDBsum 7 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 5 RefSeq 1 SAM 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8887684

Title: ERCC4 (XPF) encodes a human nucleotide excision repair protein with eukaryotic recombination homologs.

PubMed ID: 8887684

DOI: 10.1128/mcb.16.11.6553

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8797827

Title: Xeroderma pigmentosum group F caused by a defect in a structure-specific DNA repair endonuclease.

PubMed ID: 8797827

DOI: 10.1016/s0092-8674(00)80155-5

PubMed ID: 10447254

Title: A summary of mutations in the UV-sensitive disorders: xeroderma pigmentosum, Cockayne syndrome, and trichothiodystrophy.

PubMed ID: 10447254

DOI: 10.1002/(sici)1098-1004(1999)14:1<9::aid-humu2>3.0.co;2-6

PubMed ID: 10413517

Title: Domain mapping of the DNA binding, endonuclease, and ERCC1 binding properties of the human DNA repair protein XPF.

PubMed ID: 10413517

DOI: 10.1021/bi990591+

PubMed ID: 11790111

Title: Contribution of XPF functional domains to the 5' and 3' incisions produced at the site of a psoralen interstrand cross-link.

PubMed ID: 11790111

DOI: 10.1021/bi011614z

PubMed ID: 19596235

Title: Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair.

PubMed ID: 19596235

DOI: 10.1016/j.cell.2009.06.030

PubMed ID: 19596236

Title: Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases.

PubMed ID: 19596236

DOI: 10.1016/j.cell.2009.06.029

PubMed ID: 19595721

Title: Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair.

PubMed ID: 19595721

DOI: 10.1016/j.molcel.2009.06.020

PubMed ID: 19595722

Title: Drosophila MUS312 and the vertebrate ortholog BTBD12 interact with DNA structure-specific endonucleases in DNA repair and recombination.

PubMed ID: 19595722

DOI: 10.1016/j.molcel.2009.06.019

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 25538220

Title: USP45 deubiquitylase controls ERCC1-XPF endonuclease-mediated DNA damage responses.

PubMed ID: 25538220

DOI: 10.15252/embj.201489184

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 32034146

Title: Acetylation of XPF by TIP60 facilitates XPF-ERCC1 complex assembly and activation.

PubMed ID: 32034146

DOI: 10.1038/s41467-020-14564-x

PubMed ID: 16076955

Title: Crystal structure and DNA binding functions of ERCC1, a subunit of the DNA structure-specific endonuclease XPF-ERCC1.

PubMed ID: 16076955

DOI: 10.1073/pnas.0504341102

PubMed ID: 16338413

Title: The structure of the human ERCC1/XPF interaction domains reveals a complementary role for the two proteins in nucleotide excision repair.

PubMed ID: 16338413

DOI: 10.1016/j.str.2005.08.014

PubMed ID: 9485007

Title: Nonconservative amino acid substitution variants exist at polymorphic frequency in DNA repair genes in healthy humans.

PubMed ID: 9485007

PubMed ID: 9580660

Title: Characterization of molecular defects in Xeroderma pigmentosum group F in relation to its clinically mild symptoms.

PubMed ID: 9580660

DOI: 10.1093/hmg/7.6.969

PubMed ID: 9579555

Title: Homozygous R788W point mutation in the XPF gene of a patient with xeroderma pigmentosum and late-onset neurologic disease.

PubMed ID: 9579555

DOI: 10.1046/j.1523-1747.1998.00171.x

PubMed ID: 10479728

Title: Polymorphisms in the human DNA repair gene XPF.

PubMed ID: 10479728

DOI: 10.1016/s1383-5726(99)00008-4

PubMed ID: 17183314

Title: A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis.

PubMed ID: 17183314

DOI: 10.1038/nature05456

PubMed ID: 23623386

Title: Mutations in ERCC4, encoding the DNA-repair endonuclease XPF, cause Fanconi anemia.

PubMed ID: 23623386

DOI: 10.1016/j.ajhg.2013.04.002

PubMed ID: 23623389

Title: Malfunction of nuclease ERCC1-XPF results in diverse clinical manifestations and causes Cockayne syndrome, xeroderma pigmentosum, and Fanconi anemia.

PubMed ID: 23623389

DOI: 10.1016/j.ajhg.2013.04.007

PubMed ID: 24027083

Title: Evaluation of rare variants in the new fanconi anemia gene ERCC4 (FANCQ) as familial breast/ovarian cancer susceptibility alleles.

PubMed ID: 24027083

DOI: 10.1002/humu.22438

Sequence Information:

  • Length: 916
  • Mass: 104486
  • Checksum: C58CDE900378CCA8
  • Sequence:
    • MESGQPARRI AMAPLLEYER QLVLELLDTD GLVVCARGLG ADRLLYHFLQ LHCHPACLVL 
VLNTQPAEEE YFINQLKIEG VEHLPRRVTN EITSNSRYEV YTQGGVIFAT SRILVVDFLT 
DRIPSDLITG ILVYRAHRII ESCQEAFILR LFRQKNKRGF IKAFTDNAVA FDTGFCHVER 
VMRNLFVRKL YLWPRFHVAV NSFLEQHKPE VVEIHVSMTP TMLAIQTAIL DILNACLKEL 
KCHNPSLEVE DLSLENAIGK PFDKTIRHYL DPLWHQLGAK TKSLVQDLKI LRTLLQYLSQ 
YDCVTFLNLL ESLRATEKAF GQNSGWLFLD SSTSMFINAR ARVYHLPDAK MSKKEKISEK 
MEIKEGEETK KELVLESNPK WEALTEVLKE IEAENKESEA LGGPGQVLIC ASDDRTCSQL 
RDYITLGAEA FLLRLYRKTF EKDSKAEEVW MKFRKEDSSK RIRKSHKRPK DPQNKERAST 
KERTLKKKKR KLTLTQMVGK PEELEEEGDV EEGYRREISS SPESCPEEIK HEEFDVNLSS 
DAAFGILKEP LTIIHPLLGC SDPYALTRVL HEVEPRYVVL YDAELTFVRQ LEIYRASRPG 
KPLRVYFLIY GGSTEEQRYL TALRKEKEAF EKLIREKASM VVPEEREGRD ETNLDLVRGT 
ASADVSTDTR KAGGQEQNGT QQSIVVDMRE FRSELPSLIH RRGIDIEPVT LEVGDYILTP 
EMCVERKSIS DLIGSLNNGR LYSQCISMSR YYKRPVLLIE FDPSKPFSLT SRGALFQEIS 
SNDISSKLTL LTLHFPRLRI LWCPSPHATA ELFEELKQSK PQPDAATALA ITADSETLPE 
SEKYNPGPQD FLLKMPGVNA KNCRSLMHHV KNIAELAALS QDELTSILGN AANAKQLYDF 
IHTSFAEVVS KGKGKK

Genular Protein ID: 1868716255

Symbol: B4DXD8_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DXD8

Database IDs:

ARBA 6 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 EMBL 2 GO 3 Gene3D 2 GenomeRNAi 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 1 SMART 2 SUPFAM 2

Sequence Information:

  • Length: 466
  • Mass: 52842
  • Checksum: 70DB1C4D44A280F9
  • Sequence:
    • MKFRKEDSSK RIRKSHKRPK DPQNKERAST KERTLKKKKR KLTLTQMVGK PEELEEEGDV 
EEGYRREISS SPESCPEEIK HEEFDVNLSS DAAFGILKEP LTIIHPLLGC SDPYALTRVL 
HEVEPRYVVL YDAELTFVRQ LEIYRASRPG KPLRVYFLIY GGSTEEQRYL TALRKEKEAF 
EKLIREKASM VVPEEREGRD ETNLDLVRGT ASADVSTDTR KAGGQEQNGT QQSIVVDMRE 
FRSELPSLIH RRGIDIEPVT LEVGDYILTP EMCVERKSIS DLIGSLNNGR LYSQCISMSR 
YYKRPVLLIE FDPSKPFSLT SRGALFQEIS SNDISSKLTL LTLHFPRLRI LWCPSPHATA 
ELFEELKQSK PQPDAATALA ITADSETLPE SEKYNPGPQD FLLKMPGVNA KNCRSLMHHV 
KNIAELAALS QDELTSILGN AANAKQLYDF IHTSFAEVVS KGKGKK

Genular Protein ID: 3234413639

Symbol: A0A804HKF9_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A804HKF9

Database IDs:

ARBA 8 AlphaFoldDB 1 Bgee 1 CDD 1 CTD 1 EMBL 1 EPD 1 Ensembl 2 GO 4 Gene3D 2 GeneTree 1 HGNC 1 InterPro 5 MaxQB 1 NCBI Taxonomy 1 NCBIfam 1 PANTHER 2 PeptideAtlas 1 Pfam 1 Proteomes 2 RefSeq 1 SAM 1 SMART 2 SMR 1 SUPFAM 2

Citations:

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

Sequence Information:

  • Length: 962
  • Mass: 109645
  • Checksum: B18BEFEA803BC624
  • Sequence:
    • MESGQPARRI AMAPLLEYER QLVLELLDTD GLVVCARGLG ADRLLYHFLQ LHCHPACLVL 
VLNTQPAEEE YFINQLKIEG VEHLPRRVTN EITSNSRYEV YTQGGVIFAT SRILVVDFLT 
DRIPSDLITE ILPLTCQKHP TPGPVPSLSP QPGSLELSWP RWSQGSIQPL FRYHLGILVY 
RAHRIIESCQ EAFILRLFRQ KNKRGFIKAF TDNAVAFDTG FCHVERVMRN LFVRKLYLWP 
RFHVAVNSFL EQHKPEVVEI HVSMTPTMLA IQTAILDILN ACLKELKCHN PSLEVEDLSL 
ENAIGKPFDK TIRHYLDPLW HQLGAKTKSL VQDLKILRTL LQYLSQYDCV TFLNLLESLR 
ATEKAFGQNS GWLFLDSSTS MFINARARVY HLPDAKMSKK EKISEKMEIK EGEETKKELV 
LESNPKWEAL TEVLKEIEAE NKESEALGGP GQVLICASDD RTCSQLRDYI TLGAEAFLLR 
LYRKTFEKDS KAEEVWMKFR KEDSSKRIRK SHKRPKDPQN KERASTKERT LKKKKRKLTL 
TQMVGKPEEL EEEGDVEEGY RREISSSPES CPEEIKHEEF DVNLSSDAAF GILKEPLTII 
HPLLGCSDPY ALTRVLHEVE PRYVVLYDAE LTFVRQLEIY RASRPGKPLR VYFLIYGGST 
EEQRYLTALR KEKEAFEKLI REKASMVVPE EREGRDETNL DLVRGTASAD VSTDTRKAGG 
QEQNGTQQSI VVDMREFRSE LPSLIHRRGI DIEPVTLEVG DYILTPEMCV ERKSISDLIG 
SLNNGRLYSQ CISMSRYYKR PVLLIEFDPS KPFSLTSRGA LFQEISSNDI SSKLTLLTLH 
FPRLRILWCP SPHATAELFE ELKQSKPQPD AATALAITAD SETLPESEKY NPGPQDFLLK 
MPGVNAKNCR SLMHHVKNIA ELAALSQDEL TSILGNAANA KQLYDFIHTS FAEVVSKGKG 
KK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.