Details for: ESR2
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: lymphocyte (CL0000542)
Fold Change: 3.12
Marker Score: 1,575 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 2.57
Marker Score: 6,428 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 2.05
Marker Score: 2,267 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 1.85
Marker Score: 774 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 1.75
Marker Score: 6,231 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 1.72
Marker Score: 1,525 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.6
Marker Score: 1,162 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 1.56
Marker Score: 3,673 - Cell Name: contractile cell (CL0000183)
Fold Change: 1.56
Marker Score: 843 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 1.54
Marker Score: 6,460 - Cell Name: melanocyte (CL0000148)
Fold Change: 1.48
Marker Score: 599 - Cell Name: mural cell (CL0008034)
Fold Change: 1.47
Marker Score: 168,965 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 1.39
Marker Score: 380 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 1.38
Marker Score: 403 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 1.36
Marker Score: 862 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 1.34
Marker Score: 29,998 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 1.34
Marker Score: 1,518 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 1.34
Marker Score: 929 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.3
Marker Score: 20,265 - Cell Name: interneuron (CL0000099)
Fold Change: 1.27
Marker Score: 578 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 1.25
Marker Score: 2,549 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 1.21
Marker Score: 378 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 1.19
Marker Score: 7,174 - Cell Name: subcutaneous fat cell (CL0002521)
Fold Change: 1.1
Marker Score: 403 - Cell Name: fast muscle cell (CL0000190)
Fold Change: 1.09
Marker Score: 329 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 1.05
Marker Score: 2,014 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 1.04
Marker Score: 626 - Cell Name: lung goblet cell (CL1000143)
Fold Change: 1.04
Marker Score: 299 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 1.03
Marker Score: 789 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 1.01
Marker Score: 343 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,812 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 1
Marker Score: 2,191 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48,037 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.98
Marker Score: 665 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,406 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.98
Marker Score: 1,318 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.98
Marker Score: 503 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.97
Marker Score: 313 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.97
Marker Score: 1,171 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.97
Marker Score: 457 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,412 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 0.95
Marker Score: 393 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.92
Marker Score: 369 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2,735 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.91
Marker Score: 5,187 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 0.9
Marker Score: 233 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.89
Marker Score: 321 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 0.88
Marker Score: 1,364 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,295 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.86
Marker Score: 411 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 0.86
Marker Score: 32,696 - Cell Name: neuron (CL0000540)
Fold Change: 0.85
Marker Score: 3,470 - Cell Name: kidney collecting duct intercalated cell (CL1001432)
Fold Change: 0.84
Marker Score: 1,386 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 0.82
Marker Score: 882 - Cell Name: fat cell (CL0000136)
Fold Change: 0.81
Marker Score: 454 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 0.8
Marker Score: 6,842 - Cell Name: monocyte (CL0000576)
Fold Change: 0.78
Marker Score: 1,014 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 0.78
Marker Score: 465 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.77
Marker Score: 1,256 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.77
Marker Score: 3,241 - Cell Name: brush cell (CL0002204)
Fold Change: 0.76
Marker Score: 697 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.76
Marker Score: 392 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.75
Marker Score: 2,888 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 0.73
Marker Score: 428 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 0.73
Marker Score: 26,953 - Cell Name: cardiac neuron (CL0010022)
Fold Change: 0.73
Marker Score: 905 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 0.71
Marker Score: 6,720 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: 0.68
Marker Score: 450 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 0.68
Marker Score: 13,593 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.68
Marker Score: 175 - Cell Name: podocyte (CL0000653)
Fold Change: 0.67
Marker Score: 246 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.65
Marker Score: 383 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 0.65
Marker Score: 9,725 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 0.64
Marker Score: 203 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 0.64
Marker Score: 4,872 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 0.63
Marker Score: 5,997 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.63
Marker Score: 664 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.63
Marker Score: 38,474 - Cell Name: papillary tips cell (CL1000597)
Fold Change: 0.61
Marker Score: 124 - Cell Name: endothelial cell of vascular tree (CL0002139)
Fold Change: 0.61
Marker Score: 889 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.61
Marker Score: 10,857 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.58
Marker Score: 368 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.56
Marker Score: 444 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 0.56
Marker Score: 2,573 - Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 0.55
Marker Score: 1,502 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 0.54
Marker Score: 170 - Cell Name: bronchial epithelial cell (CL0002328)
Fold Change: 0.54
Marker Score: 142 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.52
Marker Score: 8,399 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 0.52
Marker Score: 132 - Cell Name: basal cell of epidermis (CL0002187)
Fold Change: 0.52
Marker Score: 226 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.52
Marker Score: 17,432 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 0.5
Marker Score: 329 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 0.5
Marker Score: 2,054 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 0.49
Marker Score: 240 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.49
Marker Score: 130 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 0.49
Marker Score: 5,036 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 0.47
Marker Score: 266 - Cell Name: neuronal receptor cell (CL0000006)
Fold Change: 0.47
Marker Score: 210 - Cell Name: rod bipolar cell (CL0000751)
Fold Change: 0.46
Marker Score: 242 - Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: 0.44
Marker Score: 1,836
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1393377049
Symbol: ESR2_HUMAN
Name: Estrogen receptor beta
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9473491
Title: The complete primary structure of human estrogen receptor beta (hERbeta) and its heterodimerization with ER alpha in vivo and in vitro.
PubMed ID: 9473491
PubMed ID: 9636657
Title: Cloning and characterization of human estrogen receptor beta isoforms.
PubMed ID: 9636657
PubMed ID: 9685228
Title: Estrogen receptor-beta mRNA variants in human and murine tissues.
PubMed ID: 9685228
PubMed ID: 9671811
Title: Molecular cloning and characterization of human estrogen receptor beta cx: a potential inhibitor of estrogen action in human.
PubMed ID: 9671811
PubMed ID: 16938840
Title: Estrogen receptor (ER)-beta isoforms: a key to understanding ER-beta signaling.
PubMed ID: 16938840
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 12508121
Title: The DNA sequence and analysis of human chromosome 14.
PubMed ID: 12508121
DOI: 10.1038/nature01348
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10964723
Title: Cloning and characterization of human estrogen receptor beta promoter.
PubMed ID: 10964723
PubMed ID: 8769313
Title: ER beta: identification and characterization of a novel human estrogen receptor.
PubMed ID: 8769313
PubMed ID: 9267036
Title: Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300.
PubMed ID: 9267036
PubMed ID: 9325313
Title: Human estrogen receptor beta binds DNA in a manner similar to and dimerizes with estrogen receptor alpha.
PubMed ID: 9325313
PubMed ID: 10681503
Title: Cloning and characterization of RAP250, a nuclear receptor coactivator.
PubMed ID: 10681503
PubMed ID: 11113208
Title: CIA, a novel estrogen receptor coactivator with a bifunctional nuclear receptor interacting determinant.
PubMed ID: 11113208
PubMed ID: 11579095
Title: The proto-oncoprotein Brx activates estrogen receptor beta by a p38 mitogen-activated protein kinase pathway.
PubMed ID: 11579095
PubMed ID: 12039952
Title: Identification of protein arginine methyltransferase 2 as a coactivator for estrogen receptor alpha.
PubMed ID: 12039952
PubMed ID: 12415108
Title: Estrogen receptor-interacting protein that modulates its nongenomic activity-crosstalk with Src/Erk phosphorylation cascade.
PubMed ID: 12415108
PubMed ID: 19666546
PubMed ID: 15047147
Title: ERBP, a novel estrogen receptor binding protein enhancing the activity of estrogen receptor.
PubMed ID: 15047147
PubMed ID: 14759258
PubMed ID: 15199063
Title: An alternative splicing variant of the selenoprotein thioredoxin reductase is a modulator of estrogen signaling.
PubMed ID: 15199063
PubMed ID: 15862947
Title: Selective hormone-dependent repression of estrogen receptor beta by a p38-activated ErbB2/ErbB3 pathway.
PubMed ID: 15862947
PubMed ID: 19126643
Title: CCDC62/ERAP75 functions as a coactivator to enhance estrogen receptor beta-mediated transactivation and target gene expression in prostate cancer cells.
PubMed ID: 19126643
PubMed ID: 20074560
Title: Repression of estrogen receptor beta function by putative tumor suppressor DBC1.
PubMed ID: 20074560
PubMed ID: 29261182
Title: Biallelic and monoallelic ESR2 variants associated with 46,XY disorders of sex development.
PubMed ID: 29261182
DOI: 10.1038/gim.2017.163
PubMed ID: 30113650
Title: Early-onset complete ovarian failure and lack of puberty in a woman with mutated estrogen receptor beta (ESR2).
PubMed ID: 30113650
Sequence Information:
- Length: 530
- Mass: 59216
- Checksum: 8CAE34215992418A
- Sequence:
MDIKNSPSSL NSPSSYNCSQ SILPLEHGSI YIPSSYVDSH HEYPAMTFYS PAVMNYSIPS NVTNLEGGPG RQTTSPNVLW PTPGHLSPLV VHRQLSHLYA EPQKSPWCEA RSLEHTLPVN RETLKRKVSG NRCASPVTGP GSKRDAHFCA VCSDYASGYH YGVWSCEGCK AFFKRSIQGH NDYICPATNQ CTIDKNRRKS CQACRLRKCY EVGMVKCGSR RERCGYRLVR RQRSADEQLH CAGKAKRSGG HAPRVRELLL DALSPEQLVL TLLEAEPPHV LISRPSAPFT EASMMMSLTK LADKELVHMI SWAKKIPGFV ELSLFDQVRL LESCWMEVLM MGLMWRSIDH PGKLIFAPDL VLDRDEGKCV EGILEIFDML LATTSRFREL KLQHKEYLCV KAMILLNSSM YPLVTATQDA DSSRKLAHLL NAVTDALVWV IAKSGISSQQ QSMRLANLLM LLSHVRHASN KGMEHLLNMK CKNVVPVYDL LLEMLNAHVL RGCKSSITGS ECSPAEDSKS KEGSQNPQSQ
Genular Protein ID: 768492342
Symbol: A0A348FV93_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 474
- Mass: 53209
- Checksum: 4558F2986355FAF0
- Sequence:
MDIKNSPSSL NSPSSYNCSQ SILPLEHGSI YIPSSYVDSH HEYPAMTFYS PAVMNYSIPS NVTNLEGGPG RQTTSPNVLW PTPGHLSPLV VHRQLSHLYA EPQKSPWCEA RSLEHTLPVN RETLKRKVSG NRCASPVTGP GSKRDAHFCA VCSDYASGYH YGVWSCEGCK AFFKRSIQGH NDYICPATNQ CTIDKNRRKS CQACRLRKCY EVGMVKCGSR RERCGYRLVR RQRSADEQLH CAGKAKRSGG HAPRVRELLL DALSPEQLVL TLLEAEPPHV LISRPSAPFT EASMMMSLTK LADKELVHMI SWAKKIPGFV ELSLFDQVRL LESCWMEVLM MGLMWRSIDH PGKLIFAPDL VLDRDEGKCV EGILEIFDML LATTSRFREL KLQHKEYLCV KAMILLNSSM YPLVTATQDA DSSRKLAHLL NAVTDALVWV IAKSGISSQQ QSMRLANLLM LLSHVRHARS CVYK
Genular Protein ID: 3219624409
Symbol: Q0PTK2_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 16230778
Title: Estrogen receptors beta4 and beta5 are full length functionally distinct ERbeta isoforms: cloning from human ovary and functional characterization.
PubMed ID: 16230778
Sequence Information:
- Length: 474
- Mass: 53151
- Checksum: FD659791D0095919
- Sequence:
MDIKNSPSSL NSPSSYDCSQ SILPLEHGSI YIPSSYVDSH HEYPAMTFYS PAVMNYSIPS NVTNLEGGPG RQTTSPNVLW PTPGHLSPLV VHRQLSHLYA EPQKSPWCEA RSLEHTLPVN RETLKRKVSG NRCASPVTGP GSKRDAHFCA VCSDYASGYH YGVWSCEGCK AFFKRSIQGH NDYICPATNQ CTIDKNRRKS CQACRLRKCY EVGMVKCGSR RERCGYRLVR RQRSAGEQLH CAGKAKRSGG HAPRVRELLL DALSPEQLVL TLLEAEPPHV LISRPSAPFT EASMMMSLTK LADKELVHMI SWAKKIPGFV ELSLFDQVRL LESCWMEVLM MGLMWRSIDH PGKLIFAPDL VLDRDEGKCV EGILEIFDML LATTSRFREL KLQHKEYLCV KAMILLNSSM YPLVTATQDA DSSRKLAHLL NAVTDALVWV IAKSGISSQQ QSMRLANLLM LLSHVRHARS CVYK
Genular Protein ID: 3147762313
Symbol: F1D8N3_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 495
- Mass: 55483
- Checksum: F068DBC63DC838A6
- Sequence:
MDIKNSPSSL NSPSSYNCSQ SILPLEHGSI YIPSSYVDSH HEYPAMTFYS PAVMNYSIPS NVTNLEGGPG RQTTSPNVLW PTPGHLSPLV VHRQLSHLYA EPQKSPWCEA RSLEHTLPVN RETLKRKVSG NRCASPVTGP GSKRDAHFCA VCSDYASGYH YGVWSCEGCK AFFKRSIQGH NDYICPATNQ CTIDKNRRKS CQACRLRKCY EVGMVKCGSR RERCGYRLVR RQRSADEQLH CAGKAKRSGG HAPRVRELLL DALSPEQLVL TLLEAEPPHV LISRPSAPFT EASMMMSLTK LADKELVHMI SWAKKIPGFV ELSLFDQVRL LESCWMEVLM MGLMWRSIDH PGKLIFAPDL VLDRDEGKCV EGILEIFDML LATTSRFREL KLQHKEYLCV KAMILLNSSM YPLVTATQDA DSSRKLAHLL NAVTDALVWV IAKSGISSQQ QSMRLANLLM LLSHVRHARA EKASQTLTSF GMKMETLLPE ATMEQ
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.