Details for: EVC

Gene ID: 2121

Symbol: EVC

Ensembl ID: ENSG00000072840

Description: EvC ciliary complex subunit 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 49.4001
    Cell Significance Index: -12.5300
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 23.4827
    Cell Significance Index: -9.5400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 4.0130
    Cell Significance Index: 583.3400
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 2.5688
    Cell Significance Index: -7.8900
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 2.4382
    Cell Significance Index: 59.0600
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 1.0703
    Cell Significance Index: 20.8900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.8529
    Cell Significance Index: 169.2700
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.5245
    Cell Significance Index: 26.5100
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.5153
    Cell Significance Index: 7.0300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.3577
    Cell Significance Index: 20.0700
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.3013
    Cell Significance Index: 6.4400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.2451
    Cell Significance Index: 6.8500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.2150
    Cell Significance Index: 404.8800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.1504
    Cell Significance Index: 4.0300
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 0.1341
    Cell Significance Index: 2.2100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.1031
    Cell Significance Index: 65.5000
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.0891
    Cell Significance Index: 1.2800
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 0.0847
    Cell Significance Index: 0.7200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0728
    Cell Significance Index: 13.1300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0689
    Cell Significance Index: 106.0300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.0685
    Cell Significance Index: 4.2100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0664
    Cell Significance Index: 90.3300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0639
    Cell Significance Index: 4.9000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0544
    Cell Significance Index: 100.3800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0543
    Cell Significance Index: 24.6300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0449
    Cell Significance Index: 9.0100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0317
    Cell Significance Index: 4.3500
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0160
    Cell Significance Index: 11.0500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0082
    Cell Significance Index: 4.4800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0079
    Cell Significance Index: 0.3700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0028
    Cell Significance Index: 0.3400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0013
    Cell Significance Index: 0.5600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0015
    Cell Significance Index: -1.1300
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0125
    Cell Significance Index: -9.2900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0176
    Cell Significance Index: -6.3300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0180
    Cell Significance Index: -13.5900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0208
    Cell Significance Index: -12.9800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0234
    Cell Significance Index: -13.2200
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.0250
    Cell Significance Index: -0.4200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0302
    Cell Significance Index: -8.6900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0350
    Cell Significance Index: -0.6000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0362
    Cell Significance Index: -4.6400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0400
    Cell Significance Index: -6.8300
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0490
    Cell Significance Index: -0.8200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0513
    Cell Significance Index: -5.8800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0610
    Cell Significance Index: -7.1100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0632
    Cell Significance Index: -13.3100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0636
    Cell Significance Index: -6.6200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0711
    Cell Significance Index: -8.3900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0754
    Cell Significance Index: -3.9300
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0764
    Cell Significance Index: -7.8000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0831
    Cell Significance Index: -10.7300
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: -0.0916
    Cell Significance Index: -0.7000
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: -0.0938
    Cell Significance Index: -0.8500
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0974
    Cell Significance Index: -6.8900
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.1158
    Cell Significance Index: -3.3200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1202
    Cell Significance Index: -9.5200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1205
    Cell Significance Index: -8.1000
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.1292
    Cell Significance Index: -2.0500
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.1321
    Cell Significance Index: -1.8800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1381
    Cell Significance Index: -10.2900
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.1489
    Cell Significance Index: -3.2600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1588
    Cell Significance Index: -7.4700
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1644
    Cell Significance Index: -2.3600
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.1654
    Cell Significance Index: -2.8600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1708
    Cell Significance Index: -11.0200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1809
    Cell Significance Index: -8.0000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.1896
    Cell Significance Index: -9.8500
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.2029
    Cell Significance Index: -2.5300
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.2058
    Cell Significance Index: -5.2900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2113
    Cell Significance Index: -8.0000
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.2157
    Cell Significance Index: -3.0700
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: -0.2626
    Cell Significance Index: -4.0000
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2645
    Cell Significance Index: -9.2700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2687
    Cell Significance Index: -14.1100
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.2710
    Cell Significance Index: -3.4200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.2847
    Cell Significance Index: -7.4900
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.2921
    Cell Significance Index: -9.2400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.2930
    Cell Significance Index: -10.1800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.3103
    Cell Significance Index: -10.1600
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.3127
    Cell Significance Index: -9.2100
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.3174
    Cell Significance Index: -10.1100
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.3185
    Cell Significance Index: -13.8500
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.3244
    Cell Significance Index: -7.7800
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.3282
    Cell Significance Index: -6.8700
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: -0.3330
    Cell Significance Index: -3.6000
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.3331
    Cell Significance Index: -8.3100
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: -0.3353
    Cell Significance Index: -3.5000
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: -0.3356
    Cell Significance Index: -2.4400
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.3399
    Cell Significance Index: -3.1300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.3520
    Cell Significance Index: -9.5800
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: -0.3539
    Cell Significance Index: -4.1100
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.3626
    Cell Significance Index: -4.1500
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.3732
    Cell Significance Index: -10.9600
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.3783
    Cell Significance Index: -10.1000
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.3890
    Cell Significance Index: -14.2800
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: -0.3939
    Cell Significance Index: -4.9600
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.4084
    Cell Significance Index: -6.0300
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.4121
    Cell Significance Index: -10.2800
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.4139
    Cell Significance Index: -11.8100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** EVC is a single-copy gene located on chromosome 9q21.3, encoding a protein of 247 amino acids. The EVC protein is a subunit of the primary cilium, specifically interacting with the axoneme, the core structure of the cilium. The protein's structure is characterized by a unique combination of transmembrane and cytoplasmic domains, suggesting its role in regulating ciliary function and signaling. **Pathways and Functions** The EVC protein is involved in several key pathways that regulate cellular behavior and development: 1. **Smoothened signaling pathway**: EVC interacts with Smoothened (SMO), a receptor for Hedgehog signaling, to modulate the activity of this pathway. Abnormalities in this pathway have been linked to various diseases, including cancer and BBS. 2. **Cartilage development**: EVC is required for the proper development of cartilage, a key component of the skeletal system. Mutations in EVC can lead to abnormalities in cartilage formation, contributing to the pathogenesis of BBS. 3. **Ciliary basal body and membrane**: EVC is a critical component of the primary cilium, influencing the structure and function of the basal body and cilium membrane. 4. **Muscle organ development**: EVC is also involved in the development of muscle organs, highlighting the importance of ciliary function in regulating muscle development and function. **Clinical Significance** Mutations in the EVC gene have been associated with Bardet-Biedl syndrome, a rare genetic disorder characterized by: 1. **Obesity**: EVC mutations can lead to obesity, a significant risk factor for various diseases, including type 2 diabetes and cardiovascular disease. 2. **Renal failure**: BBS is characterized by progressive renal failure, highlighting the importance of EVC in maintaining renal function. 3. **Congenital abnormalities**: EVC mutations can lead to congenital abnormalities, including polydactyly, clubfoot, and cardiac defects. In addition to BBS, EVC mutations have been linked to other diseases, including: 1. **Retinitis pigmentosa**: A group of inherited eye disorders characterized by progressive vision loss. 2. **Cerebellar ataxia**: A neurological disorder characterized by progressive loss of coordination and balance. In conclusion, the EVC gene plays a critical role in regulating ciliary function, signaling, and development, highlighting its importance in maintaining normal cellular behavior and preventing disease. Further research is needed to fully elucidate the mechanisms by which EVC mutations lead to disease and to develop effective therapeutic strategies for individuals with EVC-related disorders.

Genular Protein ID: 2446079027

Symbol: EVC_HUMAN

Name: DWF-1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10700184

Title: Mutations in a new gene in Ellis-van Creveld syndrome and Weyers acrodental dysostosis.

PubMed ID: 10700184

DOI: 10.1038/73508

PubMed ID: 18947413

Title: Extending the spectrum of Ellis van Creveld syndrome: a large family with a mild mutation in the EVC gene.

PubMed ID: 18947413

DOI: 10.1186/1471-2350-9-92

PubMed ID: 19744229

Title: A novel missense mutation in the EVC gene underlies Ellis-van Creveld syndrome in a Pakistani family.

PubMed ID: 19744229

DOI: 10.1111/j.1442-200x.2009.02953.x

Sequence Information:

  • Length: 992
  • Mass: 111990
  • Checksum: E3ED42401138B5D4
  • Sequence:
  • MARGGAACKS DARLLLGRDA LRPAPALLAP AVLLGAALGL GLGLWLGCRA GRQRTRHQKD 
    DTQNLLKNLE SNAQTPSETG SPSRRRKREV QMSKDKEAVD ECEPPSNSNI TAFALKAKVI 
    YPINQKFRPL ADGSSNPSLH ENLKQAVLPH QPVEASPSSS LGSLSQGEKD DCSSSSSVHS 
    ATSDDRFLSR TFLRVNAFPE VLACESVDVD LCIYSLHLKD LLHLDTALRQ EKHMMFIQIF 
    KMCLLDLLPK KKSDDELYQK ILSKQEKDLE ELEKGLQVKL SNTEMSGAGD SEYITLADVE 
    KKEREYSEQL IDNMEAFWKQ MANIQHFLVD QFKCSSSKAR QLMMTLTERM IAAEGLLCDS 
    QELQALDALE RTMGRAHMAK VIEFLKLQVQ EETRCRLAAI SHGLELLAGE GKLSGRQKEE 
    LLTQQHKAFW QEAERFSREF VQRGKDLVTA SLAHQVEGTA KLTLAQEEEQ RSFLAEAQPT 
    ADPEKFLEAF HEVLERQRLM QCDLEEEENV RATEAVVALC QELYFSTVDT FQKFVDALFL 
    QTLPGMTGLP PEECDYLRQE VQENAAWQLG KSNRFRRQQW KLFQELLEQD QQVWMEECAL 
    SSVLQTHLRE DHEGTIRGVL GRLGGLTEES TRCVLQGHDL LLRSALRRLA LRGNALATLT 
    QMRLSGKKHL LQELREQRAL EQGSSQCLDE HQWQLLRALE ARVLEEASRL EEEAQQTRLQ 
    LQQRLLAEAQ EVGQLLQQHM ECAIGQALLV HARNAATKSR AKDRDDFKRT LMEAAVESVY 
    VTSAGVSRLV QAYYQQIGRI MEDHEERKLQ HLKTLQGERM ENYKLRKKQE LSNPSSGSRT 
    AGGAHETSQA VHQRMLSQQK RFLAQFPVHQ QMRLHAQQQQ AGVMDLLEAQ LETQLQEAEQ 
    NFISELAALA RVPLAESKLL PAKRGLLEKP LRTKRKKPLP QERGDLGVPN NEDLASGDQT 
    SGSLSSKRLS QQESEAGDSG NSKKMLKRRS NL

Genular Protein ID: 774783827

Symbol: E9PCN4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

Sequence Information:

  • Length: 535
  • Mass: 60000
  • Checksum: 1DF552F6323F8754
  • Sequence:
  • MARGGAACKS DARLLLGRDA LRPAPALLAP AVLLGAALGL GLGLWLGCRA GRQRTRHQKD 
    DTQNLLKNLE SNAQTPSETG SPSRRRKREV QMSKDKEAVD ECEPPSNSNI TAFALKAKVI 
    YPINQKFRPL ADGSSNPSLH ENLKQAVLPH QPVEASPSSS LGSLSQGEKD DCSSSSSVHS 
    ATSDDRFLSR TFLRVNAFPE VLACESVDVD LCIYSLHLKD LLHLDTALRQ EKHMMFIQIF 
    KMCLLDLLPK KKSDDELYQK ILSKQEKDLE ELEKGLQVKL SNTEMSGAGD SEYITLADVE 
    KKEREYSEQL IDNMEAFWKQ MANIQHFLVD QFKCSSSKAR QLMMTLTERM IAAEGLLCDS 
    QELQALDALE RTMGRAHMAK VIEFLKLQVQ EETRCRLAAI SHGLELLAGE GKLSGRQKEE 
    LLTQQHKAFW QEAERFSREF VQRGKDLVTA SLAHQVEGTA KLTLAQEEEQ RSFLAEAQPT 
    ADPEKFLEAF HEVLERQRLM QCDLEEEENV RATEAVVALC QKAMRRHRDT GKEAV

Genular Protein ID: 3013369249

Symbol: Q5U3C2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 535
  • Mass: 59970
  • Checksum: 66CB0D1203296360
  • Sequence:
  • MARGGAACKS DARLLLGRDA LRPAPALLAP AVLLGAALGL GLGLWLGCRA GRQRTRHQKD 
    DTQNLLKNLE SNAPTPSETG SPSRRRKREV QMSKDKEAVD ECEPPSNSNI TAFALKAKVI 
    YPINQKFRPL ADGSSNPSLH ENLKQAVLPH QPVEASPSSS LGSLSQGEKD DCSSSSSVHS 
    ATSDDRFLSR TFLRVNAFPE VLACESVDVD LCIYSLHLKD LLHLDTALRQ EKHMMFIQIF 
    KMCLLDLLPK KKSDDELHQK ILSKQEKDLE ELEKGLQVKL SNTEMSGAGD SEYITLADVE 
    KKEREYSEQL IDNMEAFWKQ MANIQHFLVD QFKCSSSKAR QLMMTLTERM IAAEGLLCDS 
    QELQALDALE RTMGRAHMAK VIEFLKLQVQ EETRCRLAAI SHGLELLAGE GKLSGRQKEE 
    LLTQQHKAFW QEAERFSREF VQRGKDLVKA SLAHQVEGTA KLTLAQEEEQ RSFLAEAQPT 
    ADPEKFLEAF HEVLERQRLM QCDLEEEENV RATEAVVALC QKAMRRHRDT GKEAV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.