Details for: SND1 IT1

Gene ID: 27099

Symbol: SND1 IT1

Ensembl ID: ENSG00000279078

Description: SND1 intronic transcript 1

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 20.4078
    Cell Significance Index: -9.6400
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 2.8130
    Cell Significance Index: -8.6400
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: 0.7161
    Cell Significance Index: 10.0500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.5990
    Cell Significance Index: 69.8100
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.5984
    Cell Significance Index: 6.2000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.5958
    Cell Significance Index: 37.5500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.5377
    Cell Significance Index: 32.2800
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 0.5255
    Cell Significance Index: 7.5300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.4592
    Cell Significance Index: 12.5000
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.3627
    Cell Significance Index: 39.4500
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.3533
    Cell Significance Index: 9.4500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3385
    Cell Significance Index: 305.6000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.3122
    Cell Significance Index: 31.8900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.3026
    Cell Significance Index: 15.7200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.2549
    Cell Significance Index: 51.1400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.2534
    Cell Significance Index: 5.4900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.2447
    Cell Significance Index: 39.8000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.2391
    Cell Significance Index: 6.8900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2283
    Cell Significance Index: 22.5800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.1892
    Cell Significance Index: 14.1000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1867
    Cell Significance Index: 12.9100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1821
    Cell Significance Index: 34.6500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1653
    Cell Significance Index: 90.2900
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.1544
    Cell Significance Index: 1.8400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1407
    Cell Significance Index: 6.5600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1280
    Cell Significance Index: 5.8000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.1198
    Cell Significance Index: 15.4800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.1148
    Cell Significance Index: 2.8700
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0888
    Cell Significance Index: 5.7300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0864
    Cell Significance Index: 30.9900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0837
    Cell Significance Index: 14.3000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.0762
    Cell Significance Index: 1.0400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0714
    Cell Significance Index: 9.8100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0562
    Cell Significance Index: 6.9100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0464
    Cell Significance Index: 8.3600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0402
    Cell Significance Index: 17.8000
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 0.0388
    Cell Significance Index: 0.6700
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.0242
    Cell Significance Index: 0.5600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0175
    Cell Significance Index: 1.3500
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.0108
    Cell Significance Index: 0.5400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.0005
    Cell Significance Index: 0.0300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0006
    Cell Significance Index: -0.4400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0048
    Cell Significance Index: -0.1700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0051
    Cell Significance Index: -3.7500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0076
    Cell Significance Index: -5.5500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0098
    Cell Significance Index: -5.5300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0194
    Cell Significance Index: -0.6200
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0206
    Cell Significance Index: -1.4600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0242
    Cell Significance Index: -2.7700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0243
    Cell Significance Index: -2.8700
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.0278
    Cell Significance Index: -0.5800
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.0279
    Cell Significance Index: -0.4200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0296
    Cell Significance Index: -0.6300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0372
    Cell Significance Index: -4.7700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0393
    Cell Significance Index: -1.0500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0400
    Cell Significance Index: -8.4300
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0466
    Cell Significance Index: -1.1900
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0516
    Cell Significance Index: -1.0700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0545
    Cell Significance Index: -2.5600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0578
    Cell Significance Index: -3.5500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0605
    Cell Significance Index: -8.8000
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -0.0639
    Cell Significance Index: -0.8200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0701
    Cell Significance Index: -3.6800
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.0713
    Cell Significance Index: -0.8100
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.0820
    Cell Significance Index: -2.8500
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0962
    Cell Significance Index: -5.9000
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.1033
    Cell Significance Index: -4.2300
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: -0.1175
    Cell Significance Index: -0.7300
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.1201
    Cell Significance Index: -2.0200
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: -0.1290
    Cell Significance Index: -1.7400
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.1371
    Cell Significance Index: -2.7900
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.1484
    Cell Significance Index: -5.2000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.1697
    Cell Significance Index: -4.8700
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.1784
    Cell Significance Index: -2.5400
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: -0.1888
    Cell Significance Index: -2.8300
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1918
    Cell Significance Index: -6.2800
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1984
    Cell Significance Index: -6.3200
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.1998
    Cell Significance Index: -7.3400
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.2112
    Cell Significance Index: -1.9500
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.2159
    Cell Significance Index: -3.9900
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.2163
    Cell Significance Index: -4.5900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.2229
    Cell Significance Index: -5.8600
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: -0.2244
    Cell Significance Index: -2.5400
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.2249
    Cell Significance Index: -4.8600
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.2265
    Cell Significance Index: -6.6700
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.2357
    Cell Significance Index: -5.8800
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: -0.2511
    Cell Significance Index: -3.6500
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.2718
    Cell Significance Index: -5.6900
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: -0.2772
    Cell Significance Index: -1.8400
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: -0.2802
    Cell Significance Index: -2.8900
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: -0.2840
    Cell Significance Index: -3.9400
  • Cell Name: myometrial cell (CL0002366)
    Fold Change: -0.3065
    Cell Significance Index: -3.5300
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: -0.3114
    Cell Significance Index: -2.0300
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.3146
    Cell Significance Index: -5.3000
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.3183
    Cell Significance Index: -7.9500
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: -0.3189
    Cell Significance Index: -3.3000
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.3215
    Cell Significance Index: -7.7100
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.3304
    Cell Significance Index: -14.3700
  • Cell Name: neuroendocrine cell (CL0000165)
    Fold Change: -0.3356
    Cell Significance Index: -4.2500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.3358
    Cell Significance Index: -5.6200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Expression Pattern:** The SND1 IT1 gene is significantly expressed in a wide range of cell types, including extravillous trophoblast, goblet cells, and intestinal epithelial cells. This suggests a role in maintaining tissue integrity and function. 2. **Cell Type Specificity:** The gene's expression in certain cell types, such as pancreatic A cells and absorptive cells, implies a potential role in regulating glucose and lipid metabolism. 3. **Tumor Association:** The expression of SND1 IT1 in neoplastic and abnormal cells raises concerns about its potential involvement in tumorigenesis. 4. **Intronic Nature:** As an intronic transcript, SND1 IT1 is a non-coding RNA that may regulate gene expression through various mechanisms, such as RNA interference or long non-coding RNA (lncRNA) functions. **Pathways and Functions:** 1. **Immune Response:** The expression of SND1 IT1 in goblet cells and BEST4+ intestinal epithelial cells suggests a role in modulating the intestinal immune response, potentially influencing the development of inflammatory diseases. 2. **Cell Proliferation and Differentiation:** The involvement of SND1 IT1 in regulating cell proliferation and differentiation in pancreatic A cells and absorptive cells implies a role in maintaining tissue homeostasis. 3. **Tumor Suppression:** The expression of SND1 IT1 in extravillous trophoblast and intestinal epithelial cells may contribute to tumor suppression by inhibiting cell growth and promoting apoptosis. 4. **Metabolic Regulation:** The involvement of SND1 IT1 in regulating glucose and lipid metabolism in pancreatic A cells and absorptive cells suggests a role in maintaining energy homeostasis. **Clinical Significance:** 1. **Cancer Diagnosis and Prognosis:** The expression of SND1 IT1 in neoplastic and abnormal cells may serve as a diagnostic biomarker for certain types of cancer, such as colorectal cancer. 2. **Inflammatory Diseases:** The role of SND1 IT1 in modulating the intestinal immune response may contribute to the development of inflammatory diseases, such as inflammatory bowel disease (IBD). 3. **Metabolic Disorders:** The involvement of SND1 IT1 in regulating glucose and lipid metabolism may have implications for the diagnosis and treatment of metabolic disorders, such as type 2 diabetes. 4. **Immunological Disorders:** The expression of SND1 IT1 in goblet cells and BEST4+ intestinal epithelial cells may contribute to the development of immunological disorders, such as celiac disease. In conclusion, the SND1 IT1 gene is a complex and multifaceted transcript that plays a significant role in maintaining tissue homeostasis, immune responses, and potentially, tumorigenesis. Further investigation into the SND1 IT1 gene's functions and pathways is essential to fully comprehend its significance in immunological and non-immunological processes.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.