Details for: GNAL
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 164.1323
Cell Significance Index: -25.5300 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 100.6531
Cell Significance Index: -25.5300 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 20.7469
Cell Significance Index: -25.5800 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 9.5526
Cell Significance Index: -25.5900 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 6.5640
Cell Significance Index: 290.3400 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 6.4824
Cell Significance Index: -25.5800 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 5.8710
Cell Significance Index: 222.3200 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 5.4846
Cell Significance Index: 74.8300 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 4.7656
Cell Significance Index: -10.4300 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 4.5398
Cell Significance Index: 99.4100 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 3.9920
Cell Significance Index: 268.4300 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 2.5087
Cell Significance Index: 71.5900 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.9528
Cell Significance Index: 700.4500 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 1.8937
Cell Significance Index: 1309.7400 - Cell Name: hippocampal interneuron (CL1001569)
Fold Change: 1.2901
Cell Significance Index: 16.7300 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 1.2311
Cell Significance Index: 75.6700 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.8696
Cell Significance Index: 174.4500 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.7288
Cell Significance Index: 12.4900 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.6538
Cell Significance Index: 13.9800 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.6537
Cell Significance Index: 18.2700 - Cell Name: chandelier cell (CL4023083)
Fold Change: 0.6130
Cell Significance Index: 4.9500 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.5748
Cell Significance Index: 29.8600 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.5677
Cell Significance Index: 13.6200 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.4436
Cell Significance Index: 84.4200 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.4097
Cell Significance Index: 81.3100 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.2542
Cell Significance Index: 478.5800 - Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
Fold Change: 0.2311
Cell Significance Index: 2.5500 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.1614
Cell Significance Index: 145.7500 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.1467
Cell Significance Index: 64.8800 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.1242
Cell Significance Index: 78.8500 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0841
Cell Significance Index: 129.5300 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 0.0705
Cell Significance Index: 0.8800 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.0642
Cell Significance Index: 1.8500 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.0636
Cell Significance Index: 7.8300 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0395
Cell Significance Index: 72.8700 - Cell Name: midget ganglion cell of retina (CL4023188)
Fold Change: 0.0355
Cell Significance Index: 0.3700 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.0264
Cell Significance Index: 4.2900 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.0256
Cell Significance Index: 2.5400 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0173
Cell Significance Index: 7.8700 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.0167
Cell Significance Index: 0.7500 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 0.0104
Cell Significance Index: 0.2200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0033
Cell Significance Index: -4.5000 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0046
Cell Significance Index: -0.6700 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0059
Cell Significance Index: -0.3300 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0063
Cell Significance Index: -0.7400 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.0082
Cell Significance Index: -0.1600 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0093
Cell Significance Index: -1.6700 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0124
Cell Significance Index: -7.7400 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: -0.0145
Cell Significance Index: -1.5800 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.0159
Cell Significance Index: -0.3200 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0172
Cell Significance Index: -12.7500 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0255
Cell Significance Index: -0.9000 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.0280
Cell Significance Index: -0.7000 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0309
Cell Significance Index: -22.6600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0314
Cell Significance Index: -17.6900 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0345
Cell Significance Index: -26.1000 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0408
Cell Significance Index: -22.3000 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: -0.0506
Cell Significance Index: -0.7200 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0638
Cell Significance Index: -10.9000 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -0.0695
Cell Significance Index: -4.1700 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0752
Cell Significance Index: -21.6500 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0819
Cell Significance Index: -17.2500 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: -0.0862
Cell Significance Index: -0.8200 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.0939
Cell Significance Index: -2.0400 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0974
Cell Significance Index: -12.4900 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.0990
Cell Significance Index: -6.0700 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.1129
Cell Significance Index: -15.5100 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.1138
Cell Significance Index: -1.6300 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.1147
Cell Significance Index: -7.9400 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.1295
Cell Significance Index: -3.5300 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.1385
Cell Significance Index: -4.4100 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1736
Cell Significance Index: -22.4300 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.1761
Cell Significance Index: -13.5200 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.1823
Cell Significance Index: -8.5000 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.1875
Cell Significance Index: -4.8200 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.1893
Cell Significance Index: -13.3900 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.2145
Cell Significance Index: -24.5700 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.2156
Cell Significance Index: -25.4200 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.2226
Cell Significance Index: -25.4100 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.2243
Cell Significance Index: -22.9100 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.2245
Cell Significance Index: -4.8500 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -0.2258
Cell Significance Index: -2.4600 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: -0.2269
Cell Significance Index: -1.7400 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2286
Cell Significance Index: -23.8000 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.2534
Cell Significance Index: -15.9700 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.2986
Cell Significance Index: -2.7500 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.3016
Cell Significance Index: -23.8900 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.3132
Cell Significance Index: -23.3400 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: -0.3209
Cell Significance Index: -4.0500 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.3637
Cell Significance Index: -15.8100 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.3706
Cell Significance Index: -19.4600 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.3766
Cell Significance Index: -7.8600 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.3773
Cell Significance Index: -17.7400 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.3807
Cell Significance Index: -24.5600 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.3948
Cell Significance Index: -12.9300 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.3953
Cell Significance Index: -12.6600 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: -0.4185
Cell Significance Index: -5.0100 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.4300
Cell Significance Index: -8.9200 - Cell Name: keratocyte (CL0002363)
Fold Change: -0.4501
Cell Significance Index: -7.1400 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: -0.5157
Cell Significance Index: -10.1500
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 4000738685
Symbol: GNAL_HUMAN
Name: Guanine nucleotide-binding protein G(olf) subunit alpha
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8243272
Title: Human G(olf) alpha: complementary deoxyribonucleic acid structure and expression in pancreatic islets and other tissues outside the olfactory neuroepithelium and central nervous system.
PubMed ID: 8243272
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16177791
Title: DNA sequence and analysis of human chromosome 18.
PubMed ID: 16177791
DOI: 10.1038/nature03983
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 23994616
Title: A novel Galphas-binding protein, Gas-2 like 2, facilitates the signaling of the A2A adenosine receptor.
PubMed ID: 23994616
PubMed ID: 23222958
Sequence Information:
- Length: 381
- Mass: 44308
- Checksum: 9A73D2982FF9C9A3
- Sequence:
MGCLGGNSKT TEDQGVDEKE RREANKKIEK QLQKERLAYK ATHRLLLLGA GESGKSTIVK QMRILHVNGF NPEEKKQKIL DIRKNVKDAI VTIVSAMSTI IPPVPLANPE NQFRSDYIKS IAPITDFEYS QEFFDHVKKL WDDEGVKACF ERSNEYQLID CAQYFLERID SVSLVDYTPT DQDLLRCRVL TSGIFETRFQ VDKVNFHMFD VGGQRDERRK WIQCFNDVTA IIYVAACSSY NMVIREDNNT NRLRESLDLF ESIWNNRWLR TISIILFLNK QDMLAEKVLA GKSKIEDYFP EYANYTVPED ATPDAGEDPK VTRAKFFIRD LFLRISTATG DGKHYCYPHF TCAVDTENIR RVFNDCRDII QRMHLKQYEL L
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.