Details for: GRIN2B

Gene ID: 2904

Symbol: GRIN2B

Ensembl ID: ENSG00000273079

Description: glutamate ionotropic receptor NMDA type subunit 2B

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 6.8543
    Cell Significance Index: 195.6000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 6.2764
    Cell Significance Index: 277.6200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 6.2462
    Cell Significance Index: 420.0000
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 5.9718
    Cell Significance Index: 226.1400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 5.5664
    Cell Significance Index: 342.1400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 5.1634
    Cell Significance Index: 1852.0200
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: 4.8464
    Cell Significance Index: 62.8500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 3.5325
    Cell Significance Index: 708.6200
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 3.4604
    Cell Significance Index: 82.9900
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: 2.9431
    Cell Significance Index: 39.2600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 2.8851
    Cell Significance Index: 1995.4100
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 1.5170
    Cell Significance Index: 11.6400
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.0374
    Cell Significance Index: 197.4300
  • Cell Name: chandelier cell (CL4023083)
    Fold Change: 0.9202
    Cell Significance Index: 7.4300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.6772
    Cell Significance Index: 611.4500
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 0.6564
    Cell Significance Index: 6.2500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4251
    Cell Significance Index: 42.0500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.3449
    Cell Significance Index: 531.0300
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 0.1623
    Cell Significance Index: 3.2100
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.1445
    Cell Significance Index: 23.5000
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: 0.0677
    Cell Significance Index: 1.3600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0378
    Cell Significance Index: 69.7300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.0344
    Cell Significance Index: 5.0100
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: 0.0257
    Cell Significance Index: 0.2800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 0.0141
    Cell Significance Index: 0.4600
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: -0.0003
    Cell Significance Index: -0.0100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0062
    Cell Significance Index: -8.4700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0181
    Cell Significance Index: -34.0300
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.0250
    Cell Significance Index: -0.3100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0575
    Cell Significance Index: -2.0200
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0611
    Cell Significance Index: -0.8800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0679
    Cell Significance Index: -49.7800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0704
    Cell Significance Index: -44.7200
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.0753
    Cell Significance Index: -8.1900
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.0777
    Cell Significance Index: -0.9800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0783
    Cell Significance Index: -15.5400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0945
    Cell Significance Index: -42.8800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0955
    Cell Significance Index: -70.7500
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1088
    Cell Significance Index: -2.3100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.1091
    Cell Significance Index: -59.5700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.1204
    Cell Significance Index: -5.4600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1266
    Cell Significance Index: -71.4200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1615
    Cell Significance Index: -46.4800
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.1681
    Cell Significance Index: -2.0100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.1718
    Cell Significance Index: -4.9500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.2102
    Cell Significance Index: -5.8800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.2256
    Cell Significance Index: -5.6400
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2375
    Cell Significance Index: -7.5700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.2596
    Cell Significance Index: -46.8000
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.2759
    Cell Significance Index: -4.1900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.3151
    Cell Significance Index: -36.7200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.3378
    Cell Significance Index: -71.1500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.3639
    Cell Significance Index: -62.1400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.3917
    Cell Significance Index: -48.1600
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.4029
    Cell Significance Index: -4.7000
  • Cell Name: melanocyte of skin (CL1000458)
    Fold Change: -0.4167
    Cell Significance Index: -5.8400
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.4209
    Cell Significance Index: -3.9900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.4325
    Cell Significance Index: -55.8800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.4542
    Cell Significance Index: -62.3800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.4661
    Cell Significance Index: -32.2300
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.5036
    Cell Significance Index: -59.3900
  • Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
    Fold Change: -0.5058
    Cell Significance Index: -5.5800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.5107
    Cell Significance Index: -52.1700
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.5138
    Cell Significance Index: -11.1000
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.5360
    Cell Significance Index: -23.3100
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.5360
    Cell Significance Index: -13.3700
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.5479
    Cell Significance Index: -9.3900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.5630
    Cell Significance Index: -64.5000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.5729
    Cell Significance Index: -59.6500
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.6167
    Cell Significance Index: -7.6900
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.6326
    Cell Significance Index: -37.9800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.7153
    Cell Significance Index: -54.8900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.7584
    Cell Significance Index: -56.5200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.7977
    Cell Significance Index: -41.8800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.8000
    Cell Significance Index: -37.3000
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.8016
    Cell Significance Index: -28.0800
  • Cell Name: myeloid dendritic cell (CL0000782)
    Fold Change: -0.8033
    Cell Significance Index: -6.3000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.8320
    Cell Significance Index: -51.0100
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.8557
    Cell Significance Index: -17.8600
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.9180
    Cell Significance Index: -6.2200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.9466
    Cell Significance Index: -61.0700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -1.0086
    Cell Significance Index: -56.6000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -1.0177
    Cell Significance Index: -53.0100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -1.0343
    Cell Significance Index: -48.6100
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -1.1569
    Cell Significance Index: -22.7700
  • Cell Name: intratelencephalic-projecting glutamatergic cortical neuron (CL4023008)
    Fold Change: -1.1828
    Cell Significance Index: -12.1600
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -1.1830
    Cell Significance Index: -23.5900
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: -1.1985
    Cell Significance Index: -12.0900
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -1.2455
    Cell Significance Index: -15.7200
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -1.2790
    Cell Significance Index: -46.9500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -1.3824
    Cell Significance Index: -29.9500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -1.3856
    Cell Significance Index: -48.1500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -1.4066
    Cell Significance Index: -45.0500
  • Cell Name: professional antigen presenting cell (CL0000145)
    Fold Change: -1.5000
    Cell Significance Index: -13.5600
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -1.5052
    Cell Significance Index: -38.6900
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -1.5512
    Cell Significance Index: -37.5800
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -1.5559
    Cell Significance Index: -20.7400
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -1.6117
    Cell Significance Index: -18.3100
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -1.6835
    Cell Significance Index: -35.9900
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -1.7670
    Cell Significance Index: -52.0500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** GRIN2B is a gene that encodes for a subunit of the NMDA receptor, a type of glutamate receptor that is involved in synaptic plasticity and learning. The GRIN2B gene is highly expressed in neurons, particularly in the cerebral cortex and hippocampus. It is also found in other neural cells, such as astrocytes and oligodendrocytes. The GRIN2B gene is part of the NMDAR gene family, which includes several other subunits that are involved in the regulation of NMDA receptor function. **Pathways and Functions:** GRIN2B is involved in various signaling pathways, including: 1. **Calcium-mediated signaling:** GRIN2B plays a crucial role in the regulation of calcium influx into neurons, which is essential for synaptic plasticity and learning. 2. **Excitatory chemical synaptic transmission:** GRIN2B is involved in the transmission of excitatory signals across chemical synapses, which is critical for the regulation of neuronal activity. 3. **Long-term potentiation:** GRIN2B is involved in the regulation of long-term potentiation, a process by which synaptic strength is increased through repeated stimulation. 4. **Learning and memory:** GRIN2B is involved in the regulation of learning and memory, particularly in the hippocampus and cerebral cortex. 5. **Neurodevelopmental disorders:** GRIN2B has been implicated in various neurodevelopmental disorders, including autism spectrum disorder, schizophrenia, and attention deficit hyperactivity disorder. **Clinical Significance:** GRIN2B has been implicated in various neurological and psychiatric disorders, including: 1. **Autism spectrum disorder:** Variants of the GRIN2B gene have been associated with an increased risk of autism spectrum disorder. 2. **Schizophrenia:** GRIN2B has been implicated in the pathophysiology of schizophrenia, particularly in the regulation of dopamine release. 3. **Attention deficit hyperactivity disorder:** GRIN2B has been implicated in the regulation of attention and impulse control in individuals with attention deficit hyperactivity disorder. 4. **Neurodegenerative disorders:** GRIN2B has been implicated in the regulation of synaptic plasticity in neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease. In conclusion, the GRIN2B gene plays a critical role in the regulation of synaptic plasticity, learning, and memory. Its dysregulation has been implicated in various neurological and psychiatric disorders, highlighting the importance of further research into the molecular mechanisms underlying these conditions.

Genular Protein ID: 1955559397

Symbol: NMDE2_HUMAN

Name: Glutamate receptor ionotropic, NMDA 2B

UniProtKB Accession Codes:

Q13224 Q12919 Q13220 Q13225 Q14CU4 Q9UM56

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CTD 1 ChEBI 6 ChEMBL 1 ChiTaRS 1 ComplexPortal 2 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 31 DrugCentral 1 EMBL 8 EMDB 1 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 41 Gene3D 2 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 5 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 3 OrthoDB 1 PANTHER 2 PDB 13 PDBsum 13 PIR 2 PRINTS 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 11 RefSeq 4 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7999784

Title: Human N-methyl-D-aspartate receptor modulatory subunit hNR3: cloning and sequencing of the cDNA and primary structure of the protein.

PubMed ID: 7999784

DOI: 10.1016/0167-4781(94)00189-a

PubMed ID: 8768735

Title: Cloning and functional characterization of human heteromeric N-methyl-D-aspartate receptors.

PubMed ID: 8768735

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7959773

Title: Mapping of the human NMDAR2B receptor subunit gene (GRIN2B) to chromosome 12p12.

PubMed ID: 7959773

DOI: 10.1006/geno.1994.1366

PubMed ID: 9547169

Title: mRNA distribution in adult human brain of GRIN2B, a N-methyl-D-aspartate (NMDA) receptor subunit.

PubMed ID: 9547169

DOI: 10.1016/s0304-3940(97)00853-7

PubMed ID: 10748157

Title: Interaction of the tumor suppressor PTEN/MMAC with a PDZ domain of MAGI3, a novel membrane-associated guanylate kinase.

PubMed ID: 10748157

DOI: 10.1074/jbc.m909741199

PubMed ID: 27458189

Title: Synaptonuclear messenger PRR7 inhibits c-Jun ubiquitination and regulates NMDA-mediated excitotoxicity.

PubMed ID: 27458189

DOI: 10.15252/embj.201593070

PubMed ID: 20890276

Title: Mutations in GRIN2A and GRIN2B encoding regulatory subunits of NMDA receptors cause variable neurodevelopmental phenotypes.

PubMed ID: 20890276

DOI: 10.1038/ng.677

PubMed ID: 26919761

Title: Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design.

PubMed ID: 26919761

DOI: 10.1021/acs.jmedchem.5b02010

PubMed ID: 26875626

Title: Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function.

PubMed ID: 26875626

DOI: 10.1016/j.neuron.2016.01.016

PubMed ID: 28130356

Title: Mutation Disrupts Dendritic Morphology and Synaptic Transmission, and Causes ASD-Related Behaviors.

PubMed ID: 28130356

DOI: 10.1523/jneurosci.2068-16.2017

PubMed ID: 28126851

Title: Functional evaluation of a de novo GRIN2A mutation identified in a patient with profound global developmental delay and refractory epilepsy.

PubMed ID: 28126851

DOI: 10.1124/mol.116.106781

PubMed ID: 26912815

Title: A Novel Binding Mode Reveals Two Distinct Classes of NMDA Receptor GluN2B-selective Antagonists.

PubMed ID: 26912815

DOI: 10.1124/mol.115.103036

PubMed ID: 22833210

Title: Rare mutations in N-methyl-D-aspartate glutamate receptors in autism spectrum disorders and schizophrenia.

PubMed ID: 22833210

DOI: 10.1038/tp.2011.52

PubMed ID: 23033978

Title: Diagnostic exome sequencing in persons with severe intellectual disability.

PubMed ID: 23033978

DOI: 10.1056/nejmoa1206524

PubMed ID: 23160955

Title: Multiplex targeted sequencing identifies recurrently mutated genes in autism spectrum disorders.

PubMed ID: 23160955

DOI: 10.1126/science.1227764

PubMed ID: 24272827

Title: GRIN2B mutations in West syndrome and intellectual disability with focal epilepsy.

PubMed ID: 24272827

DOI: 10.1002/ana.24073

PubMed ID: 24863970

Title: Three rare diseases in one sib pair: RAI1, PCK1, GRIN2B mutations associated with Smith-Magenis Syndrome, cytosolic PEPCK deficiency and NMDA receptor glutamate insensitivity.

PubMed ID: 24863970

DOI: 10.1016/j.ymgme.2014.04.001

PubMed ID: 25356899

Title: De novo mutations in moderate or severe intellectual disability.

PubMed ID: 25356899

DOI: 10.1371/journal.pgen.1004772

PubMed ID: 27839871

Title: Mechanistic insight into NMDA receptor dysregulation by rare variants in the GluN2A and GluN2B agonist binding domains.

PubMed ID: 27839871

DOI: 10.1016/j.ajhg.2016.10.002

PubMed ID: 27864847

Title: Diagnostic targeted resequencing in 349 patients with drug-resistant pediatric epilepsies identifies causative mutations in 30 different genes.

PubMed ID: 27864847

DOI: 10.1002/humu.23149

PubMed ID: 28095420

Title: Molecular mechanism of disease-associated mutations in the pre-M1 helix of NMDA receptors and potential rescue pharmacology.

PubMed ID: 28095420

DOI: 10.1371/journal.pgen.1006536

PubMed ID: 38538865

Title: De novo GRIN variants in M3 helix associated with neurological disorders control channel gating of NMDA receptor.

PubMed ID: 38538865

DOI: 10.1007/s00018-023-05069-z

Sequence Information:

  • Length: 1484
  • Mass: 166367
  • Checksum: 40AEB12BE6E50CEF
  • Sequence:
    • MKPRAECCSP KFWLVLAVLA VSGSRARSQK SPPSIGIAVI LVGTSDEVAI KDAHEKDDFH 
HLSVVPRVEL VAMNETDPKS IITRICDLMS DRKIQGVVFA DDTDQEAIAQ ILDFISAQTL 
TPILGIHGGS SMIMADKDES SMFFQFGPSI EQQASVMLNI MEEYDWYIFS IVTTYFPGYQ 
DFVNKIRSTI ENSFVGWELE EVLLLDMSLD DGDSKIQNQL KKLQSPIILL YCTKEEATYI 
FEVANSVGLT GYGYTWIVPS LVAGDTDTVP AEFPTGLISV SYDEWDYGLP ARVRDGIAII 
TTAASDMLSE HSFIPEPKSS CYNTHEKRIY QSNMLNRYLI NVTFEGRNLS FSEDGYQMHP 
KLVIILLNKE RKWERVGKWK DKSLQMKYYV WPRMCPETEE QEDDHLSIVT LEEAPFVIVE 
SVDPLSGTCM RNTVPCQKRI VTENKTDEEP GYIKKCCKGF CIDILKKISK SVKFTYDLYL 
VTNGKHGKKI NGTWNGMIGE VVMKRAYMAV GSLTINEERS EVVDFSVPFI ETGISVMVSR 
SNGTVSPSAF LEPFSADVWV MMFVMLLIVS AVAVFVFEYF SPVGYNRCLA DGREPGGPSF 
TIGKAIWLLW GLVFNNSVPV QNPKGTTSKI MVSVWAFFAV IFLASYTANL AAFMIQEEYV 
DQVSGLSDKK FQRPNDFSPP FRFGTVPNGS TERNIRNNYA EMHAYMGKFN QRGVDDALLS 
LKTGKLDAFI YDAAVLNYMA GRDEGCKLVT IGSGKVFAST GYGIAIQKDS GWKRQVDLAI 
LQLFGDGEME ELEALWLTGI CHNEKNEVMS SQLDIDNMAG VFYMLGAAMA LSLITFICEH 
LFYWQFRHCF MGVCSGKPGM VFSISRGIYS CIHGVAIEER QSVMNSPTAT MNNTHSNILR 
LLRTAKNMAN LSGVNGSPQS ALDFIRRESS VYDISEHRRS FTHSDCKSYN NPPCEENLFS 
DYISEVERTF GNLQLKDSNV YQDHYHHHHR PHSIGSASSI DGLYDCDNPP FTTQSRSISK 
KPLDIGLPSS KHSQLSDLYG KFSFKSDRYS GHDDLIRSDV SDISTHTVTY GNIEGNAAKR 
RKQQYKDSLK KRPASAKSRR EFDEIELAYR RRPPRSPDHK RYFRDKEGLR DFYLDQFRTK 
ENSPHWEHVD LTDIYKERSD DFKRDSVSGG GPCTNRSHIK HGTGDKHGVV SGVPAPWEKN 
LTNVEWEDRS GGNFCRSCPS KLHNYSTTVT GQNSGRQACI RCEACKKAGN LYDISEDNSL 
QELDQPAAPV AVTSNASTTK YPQSPTNSKA QKKNRNKLRR QHSYDTFVDL QKEEAALAPR 
SVSLKDKGRF MDGSPYAHMF EMSAGESTFA NNKSSVPTAG HHHHNNPGGG YMLSKSLYPD 
RVTQNPFIPT FGDDQCLLHG SKSYFFRQPT VAGASKARPD FRALVTNKPV VSALHGAVPA 
RFQKDICIGN QSNPCVPNNK NPRAFNGSSN GHVYEKLSSI ESDV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.