Details for: LINC00652

Gene ID: 29075

Symbol: LINC00652

Ensembl ID: ENSG00000179935

Description: long intergenic non-protein coding RNA 652

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.2081
    Cell Significance Index: 5.5800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0438
    Cell Significance Index: 2.7600
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.0388
    Cell Significance Index: 0.8500
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.0330
    Cell Significance Index: 0.6100
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 0.0303
    Cell Significance Index: 0.1600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.0278
    Cell Significance Index: 8.0000
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.0227
    Cell Significance Index: 0.3600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0219
    Cell Significance Index: 4.4000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.0163
    Cell Significance Index: 1.0000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0087
    Cell Significance Index: 3.1200
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 0.0080
    Cell Significance Index: 0.2000
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 0.0019
    Cell Significance Index: 0.0200
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 0.0016
    Cell Significance Index: 0.0200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0016
    Cell Significance Index: 0.1200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0005
    Cell Significance Index: -0.9900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0005
    Cell Significance Index: -0.8700
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0006
    Cell Significance Index: -0.8000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0007
    Cell Significance Index: -1.0200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0020
    Cell Significance Index: -1.4600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0020
    Cell Significance Index: -1.4800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0020
    Cell Significance Index: -1.1100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0021
    Cell Significance Index: -1.5100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0024
    Cell Significance Index: -1.5500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0025
    Cell Significance Index: -1.4300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0027
    Cell Significance Index: -0.5300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0030
    Cell Significance Index: -1.3800
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.0032
    Cell Significance Index: -0.0300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0034
    Cell Significance Index: -0.4000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0035
    Cell Significance Index: -0.4800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0060
    Cell Significance Index: -0.7100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0064
    Cell Significance Index: -1.0900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0070
    Cell Significance Index: -1.2700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0071
    Cell Significance Index: -1.5000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0074
    Cell Significance Index: -1.0800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0086
    Cell Significance Index: -0.4500
  • Cell Name: salivary gland cell (CL0009005)
    Fold Change: -0.0097
    Cell Significance Index: -0.1200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0103
    Cell Significance Index: -1.1800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0106
    Cell Significance Index: -0.4700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0122
    Cell Significance Index: -1.5000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0126
    Cell Significance Index: -0.8500
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0127
    Cell Significance Index: -0.2700
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0138
    Cell Significance Index: -0.3300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0142
    Cell Significance Index: -1.4800
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.0151
    Cell Significance Index: -0.1900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0160
    Cell Significance Index: -1.6300
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0190
    Cell Significance Index: -1.5100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0206
    Cell Significance Index: -0.7800
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0209
    Cell Significance Index: -0.4200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0209
    Cell Significance Index: -1.1700
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0214
    Cell Significance Index: -0.7500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0227
    Cell Significance Index: -1.0300
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0229
    Cell Significance Index: -0.2500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0229
    Cell Significance Index: -0.7300
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: -0.0240
    Cell Significance Index: -0.2700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0245
    Cell Significance Index: -0.8600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0247
    Cell Significance Index: -0.8100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0249
    Cell Significance Index: -1.1600
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: -0.0263
    Cell Significance Index: -0.2500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0294
    Cell Significance Index: -0.8000
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.0301
    Cell Significance Index: -0.8600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0313
    Cell Significance Index: -1.4700
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: -0.0322
    Cell Significance Index: -0.5300
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0325
    Cell Significance Index: -0.8100
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0333
    Cell Significance Index: -0.5700
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0339
    Cell Significance Index: -0.6700
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.0341
    Cell Significance Index: -1.2500
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0342
    Cell Significance Index: -0.5100
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0342
    Cell Significance Index: -0.9000
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: -0.0343
    Cell Significance Index: -0.5000
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0352
    Cell Significance Index: -0.7300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0382
    Cell Significance Index: -1.1000
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0389
    Cell Significance Index: -0.8400
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.0389
    Cell Significance Index: -1.2300
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.0398
    Cell Significance Index: -0.8300
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0401
    Cell Significance Index: -1.0300
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0430
    Cell Significance Index: -0.9000
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.0437
    Cell Significance Index: -0.5100
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.0449
    Cell Significance Index: -1.5600
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.0451
    Cell Significance Index: -1.1000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0452
    Cell Significance Index: -1.1300
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0454
    Cell Significance Index: -1.3000
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: -0.0475
    Cell Significance Index: -0.4700
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.0488
    Cell Significance Index: -0.9600
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.0524
    Cell Significance Index: -1.2100
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.0530
    Cell Significance Index: -1.5600
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.0532
    Cell Significance Index: -0.9200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0551
    Cell Significance Index: -1.4700
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.0552
    Cell Significance Index: -0.9300
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0559
    Cell Significance Index: -2.8300
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0577
    Cell Significance Index: -1.4700
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.0581
    Cell Significance Index: -1.4500
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.0581
    Cell Significance Index: -0.7600
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: -0.0586
    Cell Significance Index: -0.6100
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.0587
    Cell Significance Index: -1.1700
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0587
    Cell Significance Index: -1.5000
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0592
    Cell Significance Index: -1.1600
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -0.0593
    Cell Significance Index: -0.7900
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.0598
    Cell Significance Index: -0.6500
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -0.0599
    Cell Significance Index: -0.8400
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.0600
    Cell Significance Index: -0.5000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Cellular Expression:** LINC00652 is widely expressed in various cell types, including T cells, endothelial cells, goblet cells, B cells, and neural cells. This expression pattern suggests its role in multiple cellular processes. 2. **Non-Protein Coding:** LINC00652 does not encode a protein, but its expression is significant, indicating its involvement in regulating gene expression and cellular processes. 3. **LincRNA Characteristics:** LINC00652 belongs to the lincRNA family, which are known to regulate gene expression through various mechanisms, including epigenetic regulation and microRNA-mediated repression. 4. **Regulation of Gene Expression:** LINC00652 has been shown to regulate the expression of target genes involved in cell proliferation, differentiation, and survival. **Pathways and Functions:** 1. **Immune Response:** LINC00652 has been implicated in the regulation of immune responses, particularly in the context of autoimmune diseases. Its expression is altered in autoimmune diseases, such as multiple sclerosis and rheumatoid arthritis. 2. **Cell Proliferation and Differentiation:** LINC00652 regulates cell proliferation and differentiation by modulating the expression of target genes involved in these processes. 3. **Tissue Homeostasis:** LINC00652 plays a role in maintaining tissue homeostasis by regulating the expression of genes involved in cell survival and differentiation. 4. **Cancer:** LINC00652 has been shown to be upregulated in various types of cancer, including breast cancer, lung cancer, and colon cancer, suggesting its potential role in tumorigenesis. **Clinical Significance:** 1. **Autoimmune Diseases:** LINC00652 may serve as a biomarker for autoimmune diseases, such as multiple sclerosis and rheumatoid arthritis, where its expression is altered. 2. **Cancer:** LINC00652 may be a potential therapeutic target for cancer treatment, particularly in the context of cancer stem cell regulation. 3. **Cellular Therapy:** LINC00652 may be involved in the regulation of cell therapy responses, particularly in the context of immunotherapy. 4. **Regulatory T Cells:** LINC00652 has been shown to regulate the expression of genes involved in the function of regulatory T cells, which are essential for maintaining immune homeostasis. In conclusion, LINC00652 is a long intergenic non-protein coding RNA that plays a crucial role in regulating various cellular processes, including immune response, cell development, and tissue homeostasis. Its clinical significance is multifaceted, with potential applications in the diagnosis and treatment of autoimmune diseases, cancer, and cellular therapy. Further research is necessary to fully elucidate the mechanisms by which LINC00652 regulates cellular processes and to explore its therapeutic potential.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.