Details for: SCG3
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: GABAergic neuron (CL0000617)
Fold Change: 3.33
Marker Score: 13,875 - Cell Name: type G enteroendocrine cell (CL0000508)
Fold Change: 2.74
Marker Score: 943 - Cell Name: endocrine cell (CL0000163)
Fold Change: 2.63
Marker Score: 1,363 - Cell Name: type A enteroendocrine cell (CL0002067)
Fold Change: 2.32
Marker Score: 937 - Cell Name: PP cell (CL0000696)
Fold Change: 2.3
Marker Score: 519 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 2.29
Marker Score: 4,656 - Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: 2.27
Marker Score: 11,922 - Cell Name: P/D1 enteroendocrine cell (CL0002268)
Fold Change: 2.25
Marker Score: 840 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 2.06
Marker Score: 2,485 - Cell Name: peripheral nervous system neuron (CL2000032)
Fold Change: 2
Marker Score: 2,248 - Cell Name: glycinergic amacrine cell (CL4030028)
Fold Change: 1.98
Marker Score: 1,868 - Cell Name: chromaffin cell (CL0000166)
Fold Change: 1.97
Marker Score: 2,775 - Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
Fold Change: 1.96
Marker Score: 660 - Cell Name: inhibitory motor neuron (CL0008015)
Fold Change: 1.76
Marker Score: 829 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 1.74
Marker Score: 4,976 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.68
Marker Score: 15,953 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 1.64
Marker Score: 32,645 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.61
Marker Score: 1,168 - Cell Name: stellate neuron (CL0000122)
Fold Change: 1.61
Marker Score: 8,622 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.58
Marker Score: 97,383 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 1.58
Marker Score: 60,002 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 1.57
Marker Score: 33,442 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.56
Marker Score: 13,405 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 1.55
Marker Score: 23,133 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 1.55
Marker Score: 7,151 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.53
Marker Score: 1,526 - Cell Name: granule cell (CL0000120)
Fold Change: 1.5
Marker Score: 11,344 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.48
Marker Score: 15,310 - Cell Name: motor neuron (CL0000100)
Fold Change: 1.43
Marker Score: 850 - Cell Name: neuronal brush cell (CL0000555)
Fold Change: 1.42
Marker Score: 4,768 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 1.41
Marker Score: 47,571 - Cell Name: neuron (CL0000540)
Fold Change: 1.41
Marker Score: 5,730 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.38
Marker Score: 5,344 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.36
Marker Score: 50,346 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 1.31
Marker Score: 10,059 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.28
Marker Score: 1,983 - Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
Fold Change: 1.23
Marker Score: 770 - Cell Name: macroglial cell (CL0000126)
Fold Change: 1.19
Marker Score: 2,725 - Cell Name: rod bipolar cell (CL0000751)
Fold Change: 1.16
Marker Score: 605 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 1.14
Marker Score: 339 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 1.12
Marker Score: 712 - Cell Name: astrocyte (CL0000127)
Fold Change: 1.11
Marker Score: 962 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 1.1
Marker Score: 4,565 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 1.09
Marker Score: 503 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 1.09
Marker Score: 10,249 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: 1.09
Marker Score: 473 - Cell Name: enteroendocrine cell (CL0000164)
Fold Change: 1.09
Marker Score: 562 - Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 1.08
Marker Score: 439 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 1.07
Marker Score: 2,185 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 1.07
Marker Score: 704 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 1.05
Marker Score: 708 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 1.04
Marker Score: 795 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 1.04
Marker Score: 251,799 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,818 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48,043 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.99
Marker Score: 509 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,408 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.98
Marker Score: 463 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,413 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.94
Marker Score: 5,350 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 0.94
Marker Score: 1,159 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.94
Marker Score: 375 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2,739 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.91
Marker Score: 327 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,287 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.85
Marker Score: 325 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.84
Marker Score: 3,518 - Cell Name: mast cell (CL0000097)
Fold Change: 0.84
Marker Score: 485 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: 0.82
Marker Score: 807 - Cell Name: brainstem motor neuron (CL2000047)
Fold Change: 0.79
Marker Score: 457 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1,261 - Cell Name: brush cell (CL0002204)
Fold Change: 0.77
Marker Score: 704 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 0.77
Marker Score: 244 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.77
Marker Score: 398 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.76
Marker Score: 501 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.72
Marker Score: 463 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.7
Marker Score: 180 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 0.69
Marker Score: 859 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 0.69
Marker Score: 287 - Cell Name: photoreceptor cell (CL0000210)
Fold Change: 0.68
Marker Score: 512 - Cell Name: radial glial cell (CL0000681)
Fold Change: 0.64
Marker Score: 235 - Cell Name: type L enteroendocrine cell (CL0002279)
Fold Change: 0.64
Marker Score: 174 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.63
Marker Score: 1,185 - Cell Name: retina horizontal cell (CL0000745)
Fold Change: 0.6
Marker Score: 578 - Cell Name: kidney proximal convoluted tubule epithelial cell (CL1000838)
Fold Change: 0.59
Marker Score: 1,228 - Cell Name: migratory enteric neural crest cell (CL0002607)
Fold Change: 0.59
Marker Score: 553 - Cell Name: M cell of gut (CL0000682)
Fold Change: 0.58
Marker Score: 151 - Cell Name: progenitor cell of endocrine pancreas (CL0002351)
Fold Change: 0.58
Marker Score: 126 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.56
Marker Score: 149 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.55
Marker Score: 442 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 0.55
Marker Score: 229 - Cell Name: CNS interneuron (CL0000402)
Fold Change: 0.55
Marker Score: 265 - Cell Name: type I enteroendocrine cell (CL0002277)
Fold Change: 0.55
Marker Score: 136 - Cell Name: ganglion interneuron (CL0000397)
Fold Change: 0.54
Marker Score: 165 - Cell Name: neural crest cell (CL0011012)
Fold Change: 0.54
Marker Score: 572 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 0.53
Marker Score: 299 - Cell Name: sympathetic neuron (CL0011103)
Fold Change: 0.51
Marker Score: 168 - Cell Name: epithelial cell of thymus (CL0002293)
Fold Change: 0.51
Marker Score: 162 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 0.5
Marker Score: 845 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 0.49
Marker Score: 1,401
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 4056837395
Symbol: SCG3_HUMAN
Name: Secretogranin-3
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 12098761
Title: Cloning and characterization of a novel human secretory protein: secretogranin III.
PubMed ID: 12098761
PubMed ID: 12975309
Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
PubMed ID: 12975309
DOI: 10.1101/gr.1293003
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16572171
Title: Analysis of the DNA sequence and duplication history of human chromosome 15.
PubMed ID: 16572171
DOI: 10.1038/nature04601
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17200173
Title: Functional single-nucleotide polymorphisms in the secretogranin III (SCG3) gene that form secretory granules with appetite-related neuropeptides are associated with obesity.
PubMed ID: 17200173
DOI: 10.1210/jc.2006-1808
PubMed ID: 19357184
Title: Secretogranin II binds to secretogranin III and forms secretory granules with orexin, neuropeptide Y, and POMC.
PubMed ID: 19357184
DOI: 10.1677/joe-08-0531
PubMed ID: 23234360
Title: LC-MS/MS characterization of O-glycosylation sites and glycan structures of human cerebrospinal fluid glycoproteins.
PubMed ID: 23234360
DOI: 10.1021/pr300963h
PubMed ID: 25326458
Title: Identification of chondroitin sulfate linkage region glycopeptides reveals prohormones as a novel class of proteoglycans.
PubMed ID: 25326458
PubMed ID: 29154827
Title: Secretogranin III promotes angiogenesis through MEK/ERK signaling pathway.
PubMed ID: 29154827
Sequence Information:
- Length: 468
- Mass: 53005
- Checksum: 5E6BBDDFFF3B8D82
- Sequence:
MGFLGTGTWI LVLVLPIQAF PKPGGSQDKS LHNRELSAER PLNEQIAEAE EDKIKKTYPP ENKPGQSNYS FVDNLNLLKA ITEKEKIEKE RQSIRSSPLD NKLNVEDVDS TKNRKLIDDY DSTKSGLDHK FQDDPDGLHQ LDGTPLTAED IVHKIAARIY EENDRAVFDK IVSKLLNLGL ITESQAHTLE DEVAEVLQKL ISKEANNYEE DPNKPTSWTE NQAGKIPEKV TPMAAIQDGL AKGENDETVS NTLTLTNGLE RRTKTYSEDN FEELQYFPNF YALLKSIDSE KEAKEKETLI TIMKTLIDFV KMMVKYGTIS PEEGVSYLEN LDEMIALQTK NKLEKNATDN ISKLFPAPSE KSHEETDSTK EEAAKMEKEY GSLKDSTKDD NSNPGGKTDE PKGKTEAYLE AIRKNIEWLK KHDKKGNKED YDLSKMRDFI NKQADAYVEK GILDKEEAEA IKRIYSSL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.