Details for: SNX10
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 176.9743
Cell Significance Index: -27.5300 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 89.1409
Cell Significance Index: -22.6100 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 67.1742
Cell Significance Index: -27.2900 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 57.1848
Cell Significance Index: -29.4200 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 28.6150
Cell Significance Index: -27.3200 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 22.3893
Cell Significance Index: -27.6100 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 10.0343
Cell Significance Index: -30.8200 - Cell Name: decidual cell (CL2000002)
Fold Change: 9.8697
Cell Significance Index: 158.3500 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 8.4514
Cell Significance Index: -22.6400 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 7.0552
Cell Significance Index: -27.8400 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 6.0450
Cell Significance Index: -13.2300 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 3.6889
Cell Significance Index: 68.1800 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 3.5969
Cell Significance Index: 55.6500 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 2.5840
Cell Significance Index: 56.5800 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 2.0944
Cell Significance Index: 109.9700 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.0878
Cell Significance Index: 418.8200 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 1.6868
Cell Significance Index: 245.2000 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 1.4967
Cell Significance Index: 42.7100 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.3411
Cell Significance Index: 481.0300 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 1.3255
Cell Significance Index: 252.2600 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.0800
Cell Significance Index: 106.8400 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 1.0163
Cell Significance Index: 17.1200 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.9818
Cell Significance Index: 20.9100 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.7658
Cell Significance Index: 51.4900 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.6726
Cell Significance Index: 133.4700 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.6405
Cell Significance Index: 75.5400 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.6173
Cell Significance Index: 557.3900 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.5544
Cell Significance Index: 90.1800 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.5308
Cell Significance Index: 23.4800 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.5110
Cell Significance Index: 19.3500 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.4852
Cell Significance Index: 52.7800 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.4682
Cell Significance Index: 323.8300 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 0.3713
Cell Significance Index: 4.6100 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.3540
Cell Significance Index: 21.2600 - Cell Name: extravillous trophoblast (CL0008036)
Fold Change: 0.3476
Cell Significance Index: 2.1600 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.2912
Cell Significance Index: 17.9000 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.2426
Cell Significance Index: 5.1900 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.1925
Cell Significance Index: 5.1500 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 0.1295
Cell Significance Index: 0.9900 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 0.0770
Cell Significance Index: 2.2600 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0554
Cell Significance Index: 40.6300 - Cell Name: hippocampal interneuron (CL1001569)
Fold Change: 0.0547
Cell Significance Index: 0.7100 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.0542
Cell Significance Index: 1.3000 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.0414
Cell Significance Index: 0.7100 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.0354
Cell Significance Index: 4.1200 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0329
Cell Significance Index: 61.9600 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0011
Cell Significance Index: 0.1900 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.0008
Cell Significance Index: 0.0600 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0025
Cell Significance Index: -0.2600 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0034
Cell Significance Index: -1.8400 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0052
Cell Significance Index: -3.2300 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.0059
Cell Significance Index: -0.1700 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0069
Cell Significance Index: -5.1400 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0088
Cell Significance Index: -3.9100 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0110
Cell Significance Index: -14.9100 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0115
Cell Significance Index: -21.1300 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0139
Cell Significance Index: -21.3900 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0141
Cell Significance Index: -7.9600 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0147
Cell Significance Index: -9.3500 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0218
Cell Significance Index: -2.9900 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0339
Cell Significance Index: -25.6500 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0341
Cell Significance Index: -0.9100 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.0365
Cell Significance Index: -0.7900 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0379
Cell Significance Index: -1.7200 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0558
Cell Significance Index: -11.7600 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.0568
Cell Significance Index: -3.9300 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0573
Cell Significance Index: -26.0200 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.0604
Cell Significance Index: -6.9000 - Cell Name: Mueller cell (CL0000636)
Fold Change: -0.0663
Cell Significance Index: -0.5100 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0745
Cell Significance Index: -21.4300 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0829
Cell Significance Index: -4.6500 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: -0.0915
Cell Significance Index: -1.2200 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.0988
Cell Significance Index: -6.2300 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.1073
Cell Significance Index: -2.7400 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.1123
Cell Significance Index: -3.9500 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1237
Cell Significance Index: -14.1700 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.1289
Cell Significance Index: -23.2300 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.1497
Cell Significance Index: -9.6600 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.1558
Cell Significance Index: -12.3400 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.1635
Cell Significance Index: -3.4700 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1783
Cell Significance Index: -23.0400 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.1856
Cell Significance Index: -2.7400 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.1945
Cell Significance Index: -23.9100 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.2047
Cell Significance Index: -12.5500 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.2152
Cell Significance Index: -4.3200 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.2316
Cell Significance Index: -29.6900 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.2515
Cell Significance Index: -11.8200 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2634
Cell Significance Index: -27.4300 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.2685
Cell Significance Index: -5.3100 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.2848
Cell Significance Index: -7.1200 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.2881
Cell Significance Index: -9.1800 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -0.2927
Cell Significance Index: -3.6500 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.3121
Cell Significance Index: -4.4700 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.3239
Cell Significance Index: -10.6100 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.3314
Cell Significance Index: -25.4300 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.3400
Cell Significance Index: -10.8900 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.3652
Cell Significance Index: -7.8900 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.4035
Cell Significance Index: -21.0200 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.4173
Cell Significance Index: -29.5200 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.4337
Cell Significance Index: -22.5300
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2888142373
Symbol: SNX10_HUMAN
Name: Sorting nexin-10
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11485546
Title: A large family of endosome-localized proteins related to sorting nexin 1.
PubMed ID: 11485546
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 12853948
PubMed ID: 12690205
Title: Human chromosome 7: DNA sequence and biology.
PubMed ID: 12690205
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17012226
Title: Sorting nexin 10 induces giant vacuoles in mammalian cells.
PubMed ID: 17012226
PubMed ID: 21844891
Title: A SNX10/V-ATPase pathway regulates ciliogenesis in vitro and in vivo.
PubMed ID: 21844891
DOI: 10.1038/cr.2011.134
PubMed ID: 22174188
Title: SNX10 is required for osteoclast formation and resorption activity.
PubMed ID: 22174188
DOI: 10.1002/jcb.24029
PubMed ID: 23123320
Title: Homozygous stop mutation in the SNX10 gene in a consanguineous Iraqi boy with osteopetrosis and corpus callosum hypoplasia.
PubMed ID: 23123320
PubMed ID: 22499339
Title: An SNX10 mutation causes malignant osteopetrosis of infancy.
PubMed ID: 22499339
PubMed ID: 23280965
Title: SNX10 mutations define a subgroup of human autosomal recessive osteopetrosis with variable clinical severity.
PubMed ID: 23280965
DOI: 10.1002/jbmr.1849
Sequence Information:
- Length: 201
- Mass: 23598
- Checksum: 665B80734D5E5C72
- Sequence:
MFPEQQKEEF VSVWVRDPRI QKEDFWHSYI DYEICIHTNS MCFTMKTSCV RRRYREFVWL RQRLQSNALL VQLPELPSKN LFFNMNNRQH VDQRRQGLED FLRKVLQNAL LLSDSSLHLF LQSHLNSEDI EACVSGQTKY SVEEAIHKFA LMNRRFPEED EEGKKENDID YDSESSSSGL GHSSDDSSSH GCKVNTAPQE S
Genular Protein ID: 3493846005
Symbol: Q8N5Z3_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 201
- Mass: 23646
- Checksum: DB4751BE51935C67
- Sequence:
MFPEQQKEEF VSVWVRDPRI QKEDFWHSYI DYEICIHTNS MCFTMKTSCV RRRYREFVWL RQRLQSNALL VQLPELPSKN LFFNMNNRQH VDQRRQGLED FLRKVLQNAL LLSYSSLHLF LQSHLNSEDI EACVSGQTKY SVEEAIHKFA LMNRRFPEED EEGKKENDID YDSESSSSGL GHSSDDSSSH GCKVNTAPQE S
Genular Protein ID: 2678619654
Symbol: B4DJM0_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11181995
Sequence Information:
- Length: 227
- Mass: 26322
- Checksum: 5E5A5A8D93FEDE2A
- Sequence:
MILMEGIGCM RHSSLTRQPK LPYRSLASAR GGLQEFVSVW VRDPRIQKED FWHSYIDYEI CIHTNSMCFT MKTSCVRRRY REFVWLRQRL QSNALLVQLP ELPSKNLFFN MNNRQHVDQR RQGLEDFLRK VLQNALLLSD SSLHLFLQSH LNSEDIEACV SGQTKYSVEE AIHKFALMNR RFPEEDEEGK KENDIDYDSE SSSSGLGHSS DDSSSHGCKV NTAPQES
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.