Details for: DSE

Gene ID: 29940

Symbol: DSE

Ensembl ID: ENSG00000111817

Description: dermatan sulfate epimerase

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 2.95
    Marker Score: 3,399
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 2.11
    Marker Score: 1,391
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 1.78
    Marker Score: 38,033
  • Cell Name: lung macrophage (CL1001603)
    Fold Change: 1.71
    Marker Score: 1,962
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 1.51
    Marker Score: 55,858
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 1.49
    Marker Score: 2,860
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.48
    Marker Score: 91,141
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.46
    Marker Score: 167,533
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.45
    Marker Score: 13,743
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.44
    Marker Score: 1,516
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.42
    Marker Score: 13,334
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 1.4
    Marker Score: 323
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.4
    Marker Score: 5,706
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.39
    Marker Score: 47,430
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 1.39
    Marker Score: 448
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.38
    Marker Score: 11,832
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 1.36
    Marker Score: 491
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.35
    Marker Score: 5,231
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 1.35
    Marker Score: 423
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 1.35
    Marker Score: 51,159
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: 1.34
    Marker Score: 330
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 1.3
    Marker Score: 5,406
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 1.29
    Marker Score: 9,914
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.29
    Marker Score: 3,034
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.28
    Marker Score: 20,033
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.28
    Marker Score: 1,972
  • Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
    Fold Change: 1.26
    Marker Score: 3,269
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: 1.26
    Marker Score: 32,283
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 1.24
    Marker Score: 4,591
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 1.21
    Marker Score: 24,088
  • Cell Name: elicited macrophage (CL0000861)
    Fold Change: 1.21
    Marker Score: 7,350
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.2
    Marker Score: 595
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.2
    Marker Score: 873
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 1.2
    Marker Score: 1,291
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.2
    Marker Score: 2,435
  • Cell Name: germ cell (CL0000586)
    Fold Change: 1.18
    Marker Score: 2,066
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 1.17
    Marker Score: 17,564
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.15
    Marker Score: 1,272
  • Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
    Fold Change: 1.13
    Marker Score: 965
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 1.12
    Marker Score: 25,004
  • Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
    Fold Change: 1.11
    Marker Score: 462
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 1.09
    Marker Score: 61,158
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 1.09
    Marker Score: 3,888
  • Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
    Fold Change: 1.09
    Marker Score: 2,117
  • Cell Name: fat cell (CL0000136)
    Fold Change: 1.08
    Marker Score: 604
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 1.07
    Marker Score: 640
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 1.06
    Marker Score: 4,916
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: 1.05
    Marker Score: 601
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 1.05
    Marker Score: 584
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 1.04
    Marker Score: 903
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 1.03
    Marker Score: 301
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 1.03
    Marker Score: 4,307
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 1.03
    Marker Score: 266
  • Cell Name: alternatively activated macrophage (CL0000890)
    Fold Change: 1
    Marker Score: 416
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,707
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47,933
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 0.99
    Marker Score: 2,379
  • Cell Name: basal cell (CL0000646)
    Fold Change: 0.99
    Marker Score: 1,282
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.99
    Marker Score: 10,222
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 0.99
    Marker Score: 1,219
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.99
    Marker Score: 5,920
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,393
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2,403
  • Cell Name: subcutaneous fat cell (CL0002521)
    Fold Change: 0.94
    Marker Score: 345
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.94
    Marker Score: 482
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: 0.93
    Marker Score: 736
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.93
    Marker Score: 438
  • Cell Name: mesothelial cell (CL0000077)
    Fold Change: 0.92
    Marker Score: 371
  • Cell Name: conventional dendritic cell (CL0000990)
    Fold Change: 0.92
    Marker Score: 633
  • Cell Name: lung ciliated cell (CL1000271)
    Fold Change: 0.91
    Marker Score: 434
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: 0.91
    Marker Score: 3,784
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2,712
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 0.88
    Marker Score: 836
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 0.87
    Marker Score: 673
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,294
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.86
    Marker Score: 311
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.86
    Marker Score: 5,614
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: 0.86
    Marker Score: 2,256
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 0.86
    Marker Score: 1,040
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.86
    Marker Score: 1,042
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.86
    Marker Score: 4,908
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 0.86
    Marker Score: 465
  • Cell Name: stromal cell (CL0000499)
    Fold Change: 0.86
    Marker Score: 1,002
  • Cell Name: macrophage (CL0000235)
    Fold Change: 0.85
    Marker Score: 950
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 0.85
    Marker Score: 356
  • Cell Name: dendritic cell, human (CL0001056)
    Fold Change: 0.84
    Marker Score: 860
  • Cell Name: podocyte (CL0000653)
    Fold Change: 0.84
    Marker Score: 309
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: 0.83
    Marker Score: 268
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 0.83
    Marker Score: 264
  • Cell Name: fibroblast of connective tissue of prostate (CL1000299)
    Fold Change: 0.82
    Marker Score: 204
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 0.82
    Marker Score: 406
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 0.81
    Marker Score: 536
  • Cell Name: prostate stromal cell (CL0002622)
    Fold Change: 0.81
    Marker Score: 204
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 0.81
    Marker Score: 2,790
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.8
    Marker Score: 383
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: 0.8
    Marker Score: 549
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.79
    Marker Score: 318
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 0.79
    Marker Score: 792
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.79
    Marker Score: 604
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 0.79
    Marker Score: 460

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** DSE is a specific epimerase enzyme that catalyzes the conversion of dermatan sulfate to its epimer, chondroitin sulfate. This reaction is a critical step in the biosynthesis and degradation of GAGs, which play vital roles in maintaining tissue architecture, cell signaling, and immune responses. DSE is primarily expressed in cells of the nervous system, muscle, and connective tissue, highlighting its importance in these tissues. **Pathways and Functions:** DSE is involved in the following pathways: 1. **Chondroitin-glucuronate 5-epimerase activity**: Catalyzes the conversion of chondroitin-glucuronate to chondroitin sulfate. 2. **Chondroitin sulfate/dermatan sulfate metabolism**: Regulates the balance between chondroitin sulfate and dermatan sulfate, two GAGs with distinct functions and tissue distributions. 3. **Chondroitin sulfate biosynthetic process**: Participates in the biosynthesis of chondroitin sulfate from glucuronic acid and N-acetylgalactosamine. 4. **Glycosaminoglycan metabolism**: Contributes to the degradation and recycling of GAGs, which is essential for maintaining tissue homeostasis. 5. **Metal ion binding**: Binds to metal ions, such as calcium and magnesium, which are required for enzyme activity. **Clinical Significance:** DSE plays a critical role in various diseases and disorders, including: 1. **Neurological disorders**: Dysregulation of GAG metabolism, including DSE activity, has been implicated in neurodegenerative diseases such as Alzheimer's and Parkinson's. 2. **Musculoskeletal disorders**: Abnormal GAG metabolism has been linked to muscular dystrophy and osteoarthritis. 3. **Cancer**: Altered GAG expression and metabolism have been observed in various types of cancer, including breast and lung cancer. 4. **Immune system dysregulation**: DSE activity has been linked to immune system disorders, such as autoimmune diseases and inflammatory conditions. In conclusion, DSE is a vital enzyme that regulates GAG metabolism, which has significant implications for our understanding of various diseases and disorders. Further research into the functions and clinical significance of DSE is necessary to uncover its full potential as a therapeutic target.

Genular Protein ID: 3230950677

Symbol: DSE_HUMAN

Name: Dermatan-sulfate epimerase

UniProtKB Accession Codes:

Q9UL01 Q5R3K6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChEBI 6 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EC 1 EMBL 3 EPD 1 Ensembl 3 ExpressionAtlas 1 GO 12 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 3 PDBsum 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 1 RefSeq 10 Rhea 3 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 UniPathway 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10679095

Title: Identification of a gene coding for a new squamous cell carcinoma antigen recognized by the CTL.

PubMed ID: 10679095

DOI: 10.4049/jimmunol.164.5.2565

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7092807

Title: Biosynthesis of dermatan sulphate. Assay and properties of the uronosyl C-5 epimerase.

PubMed ID: 7092807

DOI: 10.1042/bj2010489

PubMed ID: 16505484

Title: Biosynthesis of dermatan sulfate: chondroitin-glucuronate C5-epimerase is identical to SART2.

PubMed ID: 16505484

DOI: 10.1074/jbc.m513373200

PubMed ID: 19004833

Title: Identification of the active site of DS-epimerase 1 and requirement of N-glycosylation for enzyme function.

PubMed ID: 19004833

DOI: 10.1074/jbc.m805479200

Title: The structure of human dermatan sulfate epimerase 1 emphasizes the importance of C5-epimerization of glucuronic acid in higher organisms.

DOI: 10.1039/D0SC05971D

PubMed ID: 23704329

Title: Loss of dermatan sulfate epimerase (DSE) function results in musculocontractural Ehlers-Danlos syndrome.

PubMed ID: 23704329

DOI: 10.1093/hmg/ddt227

Sequence Information:

  • Length: 958
  • Mass: 109773
  • Checksum: A3D05C6194B4D2F9
  • Sequence:
    • MRTHTRGAPS VFFIYLLCFV SAYITDENPE VMIPFTNANY DSHPMLYFSR AEVAELQLRA 
ASSHEHIAAR LTEAVHTMLS SPLEYLPPWD PKDYSARWNE IFGNNLGALA MFCVLYPENI 
EARDMAKDYM ERMAAQPSWL VKDAPWDEVP LAHSLVGFAT AYDFLYNYLS KTQQEKFLEV 
IANASGYMYE TSYRRGWGFQ YLHNHQPTNC MALLTGSLVL MNQGYLQEAY LWTKQVLTIM 
EKSLVLLREV TDGSLYEGVA YGSYTTRSLF QYMFLVQRHF NINHFGHPWL KQHFAFMYRT 
ILPGFQRTVA IADSNYNWFY GPESQLVFLD KFVMRNGSGN WLADQIRRNR VVEGPGTPSK 
GQRWCTLHTE FLWYDGSLKS VPPPDFGTPT LHYFEDWGVV TYGSALPAEI NRSFLSFKSG 
KLGGRAIYDI VHRNKYKDWI KGWRNFNAGH EHPDQNSFTF APNGVPFITE ALYGPKYTFF 
NNVLMFSPAV SKSCFSPWVG QVTEDCSSKW SKYKHDLAAS CQGRVVAAEE KNGVVFIRGE 
GVGAYNPQLN LKNVQRNLIL LHPQLLLLVD QIHLGEESPL ETAASFFHNV DVPFEETVVD 
GVHGAFIRQR DGLYKMYWMD DTGYSEKATF ASVTYPRGYP YNGTNYVNVT MHLRSPITRA 
AYLFIGPSID VQSFTVHGDS QQLDVFIATS KHAYATYLWT GEATGQSAFA QVIADRHKIL 
FDRNSAIKSS IVPEVKDYAA IVEQNLQHFK PVFQLLEKQI LSRVRNTASF RKTAERLLRF 
SDKRQTEEAI DRIFAISQQQ QQQSKSKKNR RAGKRYKFVD AVPDIFAQIE VNEKKIRQKA 
QILAQKELPI DEDEEMKDLL DFADVTYEKH KNGGLIKGRF GQARMVTTTH SRAPSLSASY 
TRLFLILNIA IFFVMLAMQL TYFQRAQSLH GQRCLYAVLL IDSCILLWLY SSCSQSQC

Genular Protein ID: 2645704303

Symbol: A0A2R8YE23_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A2R8YE23

Database IDs:

ARBA 8 Antibodypedia 1 Bgee 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 3 Ensembl 3 GO 1 Gene3D 1 GeneTree 1 HGNC 1 InterPro 1 MassIVE 1 NCBI Taxonomy 1 PANTHER 2 Proteomes 2 RefSeq 1 SAM 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

Sequence Information:

  • Length: 228
  • Mass: 26097
  • Checksum: C24B72A87257821E
  • Sequence:
    • MRTHTRGAPS VFFIYLLCFV SAYITDENPE VMIPFTNANY DSHPMLYFSR AEVAELQLRA 
ASSHEHIAAR LTEAVHTMLS SPLEYLPPWD PKDYSARWNE IFGNNLGALA MFCVLYPENI 
EARDMAKDYM ERMAAQPSWL VKDAPWDEVP LAHSLVGFAT AYDFLYNYLS KTQQEKFLEV 
IANASGYMYE TSYRRGWGFQ YLHNHQPTNC MALLTGSLVL MNQGMMAA

Genular Protein ID: 2819260684

Symbol: B7Z1T3_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z1T3

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 GenomeRNAi 1 NCBI Taxonomy 1 RefSeq 3

Sequence Information:

  • Length: 189
  • Mass: 20040
  • Checksum: 8ADAF479443B6D35
  • Sequence:
    • MAALKGRQVY WATAGKISGW TWPHAPRRPH VLLLNGIGVG GALGSIDELL CQALSNGLNV 
PEGSLTSTCA QQPDGLIHTA KWGHVHSLSS HSPGAPNACG VLPGTTVDDG VHQDLQRVLA 
CEQVYDLEGM LDDAHSHELL AVVAAVHHHG VSKALHNGTL SFVEAFGGIP PCTVRIFRRW 
FGCLGDLEI

Genular Protein ID: 2615135044

Symbol: B7Z765_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z765

Database IDs:

ARBA 8 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 GO 2 Gene3D 2 GenomeRNAi 1 InterPro 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PhylomeDB 1 ProteomicsDB 1 RefSeq 2 SAM 1 SUPFAM 1

Sequence Information:

  • Length: 977
  • Mass: 111824
  • Checksum: A036EF317419C504
  • Sequence:
    • MGSFEDGLAA LEIWRSDATM RTHTRGAPSV FFIYLLCFVS AYITDENPEV MIPFTNANYD 
SHPMLYFSRA EVAELQLRAA SSHEHIAARL TEAVHTMLSS PLEYLPPWDP KDYSARWNEI 
FGNNLGALAM FCVLYPENIE ARDMAKDYME RMAAQPSWLV KDAPWDEVPL AHSLVGFATA 
YDFLYNYLSK TQQEKFLEVI ANASGYMYET SYRRGWGFQY LHNHQPTNCM ALLTGSLVLM 
NQGYLQEAYL WTKQVLTIME KSLVLLREVT DGSLYEGVAY GSYTTRSLFQ YMFLVQRHFN 
INHFGHPWLK QHFAFMYRTI LPGFQRTVAI ADSNYNWFYG PESQLVFLDK FVMRNGSGNW 
LADQIRRNRV VEGPGTPSKG QRWCTLHTEF LWYDGSLKSV PPPDFGTPTL HYFEDWGVVT 
YGSALPAEIN RSFLSFKSGK LGGRAIYDIV HRNKYKDWIK GWRNFNAGHE HPDQNSFTFA 
PNGVPFITEA LYGPKYTFFN NVLMFSPAVS KSCFSPWVGQ VTEDCSSKWS KYKHDLAASC 
QGRVVAAEEK NGVVFIRGEG VGAYNPQLNL KNVQRNLILL HPQLLLLVDQ IHLGEESPLE 
TAASFFHNVD VPFEETVVDG VHGAFIRQRD GLYKMYWMDD TGYSEKATFA SVTYPRGYPY 
NGTNYVNVTM HLRSPITRAA YLFIGPSIDV QSFTVHGDSQ QLDVFIATSK HAYATYLWTG 
EATGQSAFAQ VIADRHKILF DRNSAIKSSI VPEVKDYAAI VEQNLQHFKP VFQLLEKQIL 
SRVRNTASFR KTAERLLRFS DKRQTEEAID RIFAISQQQQ QQSKSKKNRR AGKRYKFVDA 
VPDIFAQIEV NEKKIRQKAQ ILAQKELPID EDEEMKDLLD FADVTYEKHK NGGLIKGRFG 
QARMVTTTHS RAPSLSASYT RLFLILNIAI FFVMLAMQLT YFQRAQSLHG QRCLYAVLLI 
DSCILLWLYS SCSQSQC

Genular Protein ID: 2150545341

Symbol: A0A2U3TZJ0_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A2U3TZJ0

Database IDs:

ARBA 8 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 3 Ensembl 2 ExpressionAtlas 1 GO 1 Gene3D 1 GeneTree 1 HGNC 1 InterPro 2 MassIVE 1 NCBI Taxonomy 1 PANTHER 2 PeptideAtlas 1 Pfam 2 Proteomes 2 RefSeq 1 SAM 1 SMR 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

Sequence Information:

  • Length: 308
  • Mass: 35674
  • Checksum: 25C79D08209EFFC3
  • Sequence:
    • MRTHTRGAPS VFFIYLLCFV SAYITDENPE VMIPFTNANY DSHPMLYFSR AEVAELQLRA 
ASSHEHIAAR LTEAVHTMLS SPLEYLPPWD PKDYSARWNE IFGNNLGALA MFCVLYPENI 
EARDMAKDYM ERMAAQPSWL VKDAPWDEVP LAHSLVGFAT AYDFLYNYLS KTQQEKFLEV 
IANASGYMYE TSYRRGWGFQ YLHNHQPTNC MALLTGSLVL MNQGYLQEAY LWTKQVLTIM 
EKSLVLLREV TDGSLYEGVA YGSYTTRSLF QYMFLVQRHF NINHFGHPWL KQHFAFMYRT 
ILPGMMAA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.