Details for: DSE
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 2.95
Marker Score: 3,399 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: 2.11
Marker Score: 1,391 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 1.78
Marker Score: 38,033 - Cell Name: lung macrophage (CL1001603)
Fold Change: 1.71
Marker Score: 1,962 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.51
Marker Score: 55,858 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 1.49
Marker Score: 2,860 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.48
Marker Score: 91,141 - Cell Name: mural cell (CL0008034)
Fold Change: 1.46
Marker Score: 167,533 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.45
Marker Score: 13,743 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.44
Marker Score: 1,516 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 1.42
Marker Score: 13,334 - Cell Name: keratocyte (CL0002363)
Fold Change: 1.4
Marker Score: 323 - Cell Name: neuron (CL0000540)
Fold Change: 1.4
Marker Score: 5,706 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 1.39
Marker Score: 47,430 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 1.39
Marker Score: 448 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.38
Marker Score: 11,832 - Cell Name: mature microglial cell (CL0002629)
Fold Change: 1.36
Marker Score: 491 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.35
Marker Score: 5,231 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 1.35
Marker Score: 423 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 1.35
Marker Score: 51,159 - Cell Name: adventitial cell (CL0002503)
Fold Change: 1.34
Marker Score: 330 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 1.3
Marker Score: 5,406 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 1.29
Marker Score: 9,914 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 1.29
Marker Score: 3,034 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.28
Marker Score: 20,033 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.28
Marker Score: 1,972 - Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
Fold Change: 1.26
Marker Score: 3,269 - Cell Name: alveolar macrophage (CL0000583)
Fold Change: 1.26
Marker Score: 32,283 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 1.24
Marker Score: 4,591 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 1.21
Marker Score: 24,088 - Cell Name: elicited macrophage (CL0000861)
Fold Change: 1.21
Marker Score: 7,350 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 1.2
Marker Score: 595 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.2
Marker Score: 873 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 1.2
Marker Score: 1,291 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 1.2
Marker Score: 2,435 - Cell Name: germ cell (CL0000586)
Fold Change: 1.18
Marker Score: 2,066 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 1.17
Marker Score: 17,564 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 1.15
Marker Score: 1,272 - Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
Fold Change: 1.13
Marker Score: 965 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 1.12
Marker Score: 25,004 - Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
Fold Change: 1.11
Marker Score: 462 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 1.09
Marker Score: 61,158 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 1.09
Marker Score: 3,888 - Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
Fold Change: 1.09
Marker Score: 2,117 - Cell Name: fat cell (CL0000136)
Fold Change: 1.08
Marker Score: 604 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 1.07
Marker Score: 640 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 1.06
Marker Score: 4,916 - Cell Name: fibroblast of breast (CL4006000)
Fold Change: 1.05
Marker Score: 601 - Cell Name: alveolar type 2 fibroblast cell (CL4028006)
Fold Change: 1.05
Marker Score: 584 - Cell Name: astrocyte (CL0000127)
Fold Change: 1.04
Marker Score: 903 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 1.03
Marker Score: 301 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 1.03
Marker Score: 4,307 - Cell Name: skin fibroblast (CL0002620)
Fold Change: 1.03
Marker Score: 266 - Cell Name: alternatively activated macrophage (CL0000890)
Fold Change: 1
Marker Score: 416 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,707 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 47,933 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 0.99
Marker Score: 2,379 - Cell Name: basal cell (CL0000646)
Fold Change: 0.99
Marker Score: 1,282 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 0.99
Marker Score: 10,222 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 0.99
Marker Score: 1,219 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.99
Marker Score: 5,920 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,393 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,403 - Cell Name: subcutaneous fat cell (CL0002521)
Fold Change: 0.94
Marker Score: 345 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.94
Marker Score: 482 - Cell Name: epithelial cell of urethra (CL1000296)
Fold Change: 0.93
Marker Score: 736 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.93
Marker Score: 438 - Cell Name: mesothelial cell (CL0000077)
Fold Change: 0.92
Marker Score: 371 - Cell Name: conventional dendritic cell (CL0000990)
Fold Change: 0.92
Marker Score: 633 - Cell Name: lung ciliated cell (CL1000271)
Fold Change: 0.91
Marker Score: 434 - Cell Name: classical monocyte (CL0000860)
Fold Change: 0.91
Marker Score: 3,784 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2,712 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 0.88
Marker Score: 836 - Cell Name: renal principal cell (CL0005009)
Fold Change: 0.87
Marker Score: 673 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,294 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.86
Marker Score: 311 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 0.86
Marker Score: 5,614 - Cell Name: fibroblast of lung (CL0002553)
Fold Change: 0.86
Marker Score: 2,256 - Cell Name: mesangial cell (CL0000650)
Fold Change: 0.86
Marker Score: 1,040 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.86
Marker Score: 1,042 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.86
Marker Score: 4,908 - Cell Name: contractile cell (CL0000183)
Fold Change: 0.86
Marker Score: 465 - Cell Name: stromal cell (CL0000499)
Fold Change: 0.86
Marker Score: 1,002 - Cell Name: macrophage (CL0000235)
Fold Change: 0.85
Marker Score: 950 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 0.85
Marker Score: 356 - Cell Name: dendritic cell, human (CL0001056)
Fold Change: 0.84
Marker Score: 860 - Cell Name: podocyte (CL0000653)
Fold Change: 0.84
Marker Score: 309 - Cell Name: mesothelial cell of epicardium (CL0011019)
Fold Change: 0.83
Marker Score: 268 - Cell Name: lens fiber cell (CL0011004)
Fold Change: 0.83
Marker Score: 264 - Cell Name: fibroblast of connective tissue of prostate (CL1000299)
Fold Change: 0.82
Marker Score: 204 - Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 0.82
Marker Score: 406 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 0.81
Marker Score: 536 - Cell Name: prostate stromal cell (CL0002622)
Fold Change: 0.81
Marker Score: 204 - Cell Name: ciliated cell (CL0000064)
Fold Change: 0.81
Marker Score: 2,790 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.8
Marker Score: 383 - Cell Name: dendritic cell (CL0000451)
Fold Change: 0.8
Marker Score: 549 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.79
Marker Score: 318 - Cell Name: Kupffer cell (CL0000091)
Fold Change: 0.79
Marker Score: 792 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.79
Marker Score: 604 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 0.79
Marker Score: 460
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3230950677
Symbol: DSE_HUMAN
Name: Dermatan-sulfate epimerase
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10679095
Title: Identification of a gene coding for a new squamous cell carcinoma antigen recognized by the CTL.
PubMed ID: 10679095
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 7092807
Title: Biosynthesis of dermatan sulphate. Assay and properties of the uronosyl C-5 epimerase.
PubMed ID: 7092807
DOI: 10.1042/bj2010489
PubMed ID: 16505484
Title: Biosynthesis of dermatan sulfate: chondroitin-glucuronate C5-epimerase is identical to SART2.
PubMed ID: 16505484
PubMed ID: 19004833
Title: Identification of the active site of DS-epimerase 1 and requirement of N-glycosylation for enzyme function.
PubMed ID: 19004833
Title: The structure of human dermatan sulfate epimerase 1 emphasizes the importance of C5-epimerization of glucuronic acid in higher organisms.
DOI: 10.1039/D0SC05971D
PubMed ID: 23704329
Title: Loss of dermatan sulfate epimerase (DSE) function results in musculocontractural Ehlers-Danlos syndrome.
PubMed ID: 23704329
DOI: 10.1093/hmg/ddt227
Sequence Information:
- Length: 958
- Mass: 109773
- Checksum: A3D05C6194B4D2F9
- Sequence:
MRTHTRGAPS VFFIYLLCFV SAYITDENPE VMIPFTNANY DSHPMLYFSR AEVAELQLRA ASSHEHIAAR LTEAVHTMLS SPLEYLPPWD PKDYSARWNE IFGNNLGALA MFCVLYPENI EARDMAKDYM ERMAAQPSWL VKDAPWDEVP LAHSLVGFAT AYDFLYNYLS KTQQEKFLEV IANASGYMYE TSYRRGWGFQ YLHNHQPTNC MALLTGSLVL MNQGYLQEAY LWTKQVLTIM EKSLVLLREV TDGSLYEGVA YGSYTTRSLF QYMFLVQRHF NINHFGHPWL KQHFAFMYRT ILPGFQRTVA IADSNYNWFY GPESQLVFLD KFVMRNGSGN WLADQIRRNR VVEGPGTPSK GQRWCTLHTE FLWYDGSLKS VPPPDFGTPT LHYFEDWGVV TYGSALPAEI NRSFLSFKSG KLGGRAIYDI VHRNKYKDWI KGWRNFNAGH EHPDQNSFTF APNGVPFITE ALYGPKYTFF NNVLMFSPAV SKSCFSPWVG QVTEDCSSKW SKYKHDLAAS CQGRVVAAEE KNGVVFIRGE GVGAYNPQLN LKNVQRNLIL LHPQLLLLVD QIHLGEESPL ETAASFFHNV DVPFEETVVD GVHGAFIRQR DGLYKMYWMD DTGYSEKATF ASVTYPRGYP YNGTNYVNVT MHLRSPITRA AYLFIGPSID VQSFTVHGDS QQLDVFIATS KHAYATYLWT GEATGQSAFA QVIADRHKIL FDRNSAIKSS IVPEVKDYAA IVEQNLQHFK PVFQLLEKQI LSRVRNTASF RKTAERLLRF SDKRQTEEAI DRIFAISQQQ QQQSKSKKNR RAGKRYKFVD AVPDIFAQIE VNEKKIRQKA QILAQKELPI DEDEEMKDLL DFADVTYEKH KNGGLIKGRF GQARMVTTTH SRAPSLSASY TRLFLILNIA IFFVMLAMQL TYFQRAQSLH GQRCLYAVLL IDSCILLWLY SSCSQSQC
Genular Protein ID: 2645704303
Symbol: A0A2R8YE23_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
Sequence Information:
- Length: 228
- Mass: 26097
- Checksum: C24B72A87257821E
- Sequence:
MRTHTRGAPS VFFIYLLCFV SAYITDENPE VMIPFTNANY DSHPMLYFSR AEVAELQLRA ASSHEHIAAR LTEAVHTMLS SPLEYLPPWD PKDYSARWNE IFGNNLGALA MFCVLYPENI EARDMAKDYM ERMAAQPSWL VKDAPWDEVP LAHSLVGFAT AYDFLYNYLS KTQQEKFLEV IANASGYMYE TSYRRGWGFQ YLHNHQPTNC MALLTGSLVL MNQGMMAA
Genular Protein ID: 2819260684
Symbol: B7Z1T3_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 189
- Mass: 20040
- Checksum: 8ADAF479443B6D35
- Sequence:
MAALKGRQVY WATAGKISGW TWPHAPRRPH VLLLNGIGVG GALGSIDELL CQALSNGLNV PEGSLTSTCA QQPDGLIHTA KWGHVHSLSS HSPGAPNACG VLPGTTVDDG VHQDLQRVLA CEQVYDLEGM LDDAHSHELL AVVAAVHHHG VSKALHNGTL SFVEAFGGIP PCTVRIFRRW FGCLGDLEI
Genular Protein ID: 2615135044
Symbol: B7Z765_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 977
- Mass: 111824
- Checksum: A036EF317419C504
- Sequence:
MGSFEDGLAA LEIWRSDATM RTHTRGAPSV FFIYLLCFVS AYITDENPEV MIPFTNANYD SHPMLYFSRA EVAELQLRAA SSHEHIAARL TEAVHTMLSS PLEYLPPWDP KDYSARWNEI FGNNLGALAM FCVLYPENIE ARDMAKDYME RMAAQPSWLV KDAPWDEVPL AHSLVGFATA YDFLYNYLSK TQQEKFLEVI ANASGYMYET SYRRGWGFQY LHNHQPTNCM ALLTGSLVLM NQGYLQEAYL WTKQVLTIME KSLVLLREVT DGSLYEGVAY GSYTTRSLFQ YMFLVQRHFN INHFGHPWLK QHFAFMYRTI LPGFQRTVAI ADSNYNWFYG PESQLVFLDK FVMRNGSGNW LADQIRRNRV VEGPGTPSKG QRWCTLHTEF LWYDGSLKSV PPPDFGTPTL HYFEDWGVVT YGSALPAEIN RSFLSFKSGK LGGRAIYDIV HRNKYKDWIK GWRNFNAGHE HPDQNSFTFA PNGVPFITEA LYGPKYTFFN NVLMFSPAVS KSCFSPWVGQ VTEDCSSKWS KYKHDLAASC QGRVVAAEEK NGVVFIRGEG VGAYNPQLNL KNVQRNLILL HPQLLLLVDQ IHLGEESPLE TAASFFHNVD VPFEETVVDG VHGAFIRQRD GLYKMYWMDD TGYSEKATFA SVTYPRGYPY NGTNYVNVTM HLRSPITRAA YLFIGPSIDV QSFTVHGDSQ QLDVFIATSK HAYATYLWTG EATGQSAFAQ VIADRHKILF DRNSAIKSSI VPEVKDYAAI VEQNLQHFKP VFQLLEKQIL SRVRNTASFR KTAERLLRFS DKRQTEEAID RIFAISQQQQ QQSKSKKNRR AGKRYKFVDA VPDIFAQIEV NEKKIRQKAQ ILAQKELPID EDEEMKDLLD FADVTYEKHK NGGLIKGRFG QARMVTTTHS RAPSLSASYT RLFLILNIAI FFVMLAMQLT YFQRAQSLHG QRCLYAVLLI DSCILLWLYS SCSQSQC
Genular Protein ID: 2150545341
Symbol: A0A2U3TZJ0_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
Sequence Information:
- Length: 308
- Mass: 35674
- Checksum: 25C79D08209EFFC3
- Sequence:
MRTHTRGAPS VFFIYLLCFV SAYITDENPE VMIPFTNANY DSHPMLYFSR AEVAELQLRA ASSHEHIAAR LTEAVHTMLS SPLEYLPPWD PKDYSARWNE IFGNNLGALA MFCVLYPENI EARDMAKDYM ERMAAQPSWL VKDAPWDEVP LAHSLVGFAT AYDFLYNYLS KTQQEKFLEV IANASGYMYE TSYRRGWGFQ YLHNHQPTNC MALLTGSLVL MNQGYLQEAY LWTKQVLTIM EKSLVLLREV TDGSLYEGVA YGSYTTRSLF QYMFLVQRHF NINHFGHPWL KQHFAFMYRT ILPGMMAA
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.