Details for: DSE

Gene ID: 29940

Symbol: DSE

Ensembl ID: ENSG00000111817

Description: dermatan sulfate epimerase

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 308.6562
    Cell Significance Index: -48.0100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 184.3927
    Cell Significance Index: -46.7700
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 94.0222
    Cell Significance Index: -44.3900
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 88.1954
    Cell Significance Index: -35.8300
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 80.4261
    Cell Significance Index: -41.3700
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 38.9633
    Cell Significance Index: -48.0400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 15.7306
    Cell Significance Index: -42.1400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 12.1843
    Cell Significance Index: -48.0800
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 11.2812
    Cell Significance Index: -24.6900
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 2.5936
    Cell Significance Index: 50.6200
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 2.2212
    Cell Significance Index: 15.0500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 2.0896
    Cell Significance Index: 28.5100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.4828
    Cell Significance Index: 426.6400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.4274
    Cell Significance Index: 286.3300
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 1.3765
    Cell Significance Index: 23.5900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.3171
    Cell Significance Index: 73.9100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.2483
    Cell Significance Index: 237.5600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.9122
    Cell Significance Index: 327.2100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.9074
    Cell Significance Index: 69.6400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.7516
    Cell Significance Index: 149.1600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.7085
    Cell Significance Index: 31.3400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.6875
    Cell Significance Index: 42.2600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.6367
    Cell Significance Index: 24.1100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.6000
    Cell Significance Index: 17.2000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.5303
    Cell Significance Index: 52.4600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.4921
    Cell Significance Index: 444.3300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.4827
    Cell Significance Index: 32.4600
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.4288
    Cell Significance Index: 10.7200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.3918
    Cell Significance Index: 48.1700
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.3198
    Cell Significance Index: 5.9100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.2999
    Cell Significance Index: 38.4400
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.2737
    Cell Significance Index: 44.5200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2706
    Cell Significance Index: 48.7800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1588
    Cell Significance Index: 21.8100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1494
    Cell Significance Index: 66.0500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.1364
    Cell Significance Index: 15.9000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0895
    Cell Significance Index: 168.5700
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.0876
    Cell Significance Index: 9.5300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0817
    Cell Significance Index: 51.8600
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 0.0466
    Cell Significance Index: 0.3800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0436
    Cell Significance Index: 67.0500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0320
    Cell Significance Index: 59.0800
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.0183
    Cell Significance Index: 0.4400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0017
    Cell Significance Index: -2.3000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0099
    Cell Significance Index: -5.4200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0215
    Cell Significance Index: -9.7600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0293
    Cell Significance Index: -18.2900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0402
    Cell Significance Index: -29.5100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0423
    Cell Significance Index: -31.3100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0594
    Cell Significance Index: -44.9600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0627
    Cell Significance Index: -35.3600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0733
    Cell Significance Index: -7.4900
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0785
    Cell Significance Index: -2.7600
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0895
    Cell Significance Index: -2.5800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.1233
    Cell Significance Index: -5.5900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1284
    Cell Significance Index: -3.3800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.1497
    Cell Significance Index: -25.5700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1588
    Cell Significance Index: -23.0900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1647
    Cell Significance Index: -10.6300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1703
    Cell Significance Index: -35.8600
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.1716
    Cell Significance Index: -11.8700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.1977
    Cell Significance Index: -5.2800
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.2165
    Cell Significance Index: -13.0000
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.2486
    Cell Significance Index: -4.1600
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.2672
    Cell Significance Index: -34.5200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.2723
    Cell Significance Index: -12.8000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.2793
    Cell Significance Index: -14.5100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.2829
    Cell Significance Index: -33.3600
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.2888
    Cell Significance Index: -7.8600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.2945
    Cell Significance Index: -6.3800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.3045
    Cell Significance Index: -8.5100
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.3366
    Cell Significance Index: -7.2000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.3692
    Cell Significance Index: -42.3000
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.3774
    Cell Significance Index: -10.7700
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.3933
    Cell Significance Index: -44.8900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.4127
    Cell Significance Index: -42.9700
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.4194
    Cell Significance Index: -11.2200
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.4538
    Cell Significance Index: -6.7000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4841
    Cell Significance Index: -38.3400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4910
    Cell Significance Index: -30.1000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.4974
    Cell Significance Index: -35.1800
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.5076
    Cell Significance Index: -26.4400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.5091
    Cell Significance Index: -37.9400
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.5143
    Cell Significance Index: -7.3900
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.5385
    Cell Significance Index: -7.6700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.5914
    Cell Significance Index: -20.5500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.6155
    Cell Significance Index: -38.7900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.6210
    Cell Significance Index: -13.2300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.6479
    Cell Significance Index: -17.3600
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.6503
    Cell Significance Index: -14.2400
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.7333
    Cell Significance Index: -15.3500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.7471
    Cell Significance Index: -23.9300
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.7600
    Cell Significance Index: -6.4600
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.7939
    Cell Significance Index: -40.1200
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.8132
    Cell Significance Index: -14.0600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.8157
    Cell Significance Index: -42.8300
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.8408
    Cell Significance Index: -36.5600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.8824
    Cell Significance Index: -28.8900
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.8889
    Cell Significance Index: -28.3100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.8890
    Cell Significance Index: -41.4500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** DSE is a specific epimerase enzyme that catalyzes the conversion of dermatan sulfate to its epimer, chondroitin sulfate. This reaction is a critical step in the biosynthesis and degradation of GAGs, which play vital roles in maintaining tissue architecture, cell signaling, and immune responses. DSE is primarily expressed in cells of the nervous system, muscle, and connective tissue, highlighting its importance in these tissues. **Pathways and Functions:** DSE is involved in the following pathways: 1. **Chondroitin-glucuronate 5-epimerase activity**: Catalyzes the conversion of chondroitin-glucuronate to chondroitin sulfate. 2. **Chondroitin sulfate/dermatan sulfate metabolism**: Regulates the balance between chondroitin sulfate and dermatan sulfate, two GAGs with distinct functions and tissue distributions. 3. **Chondroitin sulfate biosynthetic process**: Participates in the biosynthesis of chondroitin sulfate from glucuronic acid and N-acetylgalactosamine. 4. **Glycosaminoglycan metabolism**: Contributes to the degradation and recycling of GAGs, which is essential for maintaining tissue homeostasis. 5. **Metal ion binding**: Binds to metal ions, such as calcium and magnesium, which are required for enzyme activity. **Clinical Significance:** DSE plays a critical role in various diseases and disorders, including: 1. **Neurological disorders**: Dysregulation of GAG metabolism, including DSE activity, has been implicated in neurodegenerative diseases such as Alzheimer's and Parkinson's. 2. **Musculoskeletal disorders**: Abnormal GAG metabolism has been linked to muscular dystrophy and osteoarthritis. 3. **Cancer**: Altered GAG expression and metabolism have been observed in various types of cancer, including breast and lung cancer. 4. **Immune system dysregulation**: DSE activity has been linked to immune system disorders, such as autoimmune diseases and inflammatory conditions. In conclusion, DSE is a vital enzyme that regulates GAG metabolism, which has significant implications for our understanding of various diseases and disorders. Further research into the functions and clinical significance of DSE is necessary to uncover its full potential as a therapeutic target.

Genular Protein ID: 3230950677

Symbol: DSE_HUMAN

Name: Dermatan-sulfate epimerase

UniProtKB Accession Codes:

Q9UL01 Q5R3K6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChEBI 6 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EC 1 EMBL 3 Ensembl 3 ExpressionAtlas 1 GO 12 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 1 RefSeq 10 Rhea 3 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 UniPathway 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10679095

Title: Identification of a gene coding for a new squamous cell carcinoma antigen recognized by the CTL.

PubMed ID: 10679095

DOI: 10.4049/jimmunol.164.5.2565

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7092807

Title: Biosynthesis of dermatan sulphate. Assay and properties of the uronosyl C-5 epimerase.

PubMed ID: 7092807

DOI: 10.1042/bj2010489

PubMed ID: 16505484

Title: Biosynthesis of dermatan sulfate: chondroitin-glucuronate C5-epimerase is identical to SART2.

PubMed ID: 16505484

DOI: 10.1074/jbc.m513373200

PubMed ID: 19004833

Title: Identification of the active site of DS-epimerase 1 and requirement of N-glycosylation for enzyme function.

PubMed ID: 19004833

DOI: 10.1074/jbc.m805479200

Title: The structure of human dermatan sulfate epimerase 1 emphasizes the importance of C5-epimerization of glucuronic acid in higher organisms.

DOI: 10.1039/D0SC05971D

PubMed ID: 23704329

Title: Loss of dermatan sulfate epimerase (DSE) function results in musculocontractural Ehlers-Danlos syndrome.

PubMed ID: 23704329

DOI: 10.1093/hmg/ddt227

Sequence Information:

  • Length: 958
  • Mass: 109773
  • Checksum: A3D05C6194B4D2F9
  • Sequence:
    • MRTHTRGAPS VFFIYLLCFV SAYITDENPE VMIPFTNANY DSHPMLYFSR AEVAELQLRA 
ASSHEHIAAR LTEAVHTMLS SPLEYLPPWD PKDYSARWNE IFGNNLGALA MFCVLYPENI 
EARDMAKDYM ERMAAQPSWL VKDAPWDEVP LAHSLVGFAT AYDFLYNYLS KTQQEKFLEV 
IANASGYMYE TSYRRGWGFQ YLHNHQPTNC MALLTGSLVL MNQGYLQEAY LWTKQVLTIM 
EKSLVLLREV TDGSLYEGVA YGSYTTRSLF QYMFLVQRHF NINHFGHPWL KQHFAFMYRT 
ILPGFQRTVA IADSNYNWFY GPESQLVFLD KFVMRNGSGN WLADQIRRNR VVEGPGTPSK 
GQRWCTLHTE FLWYDGSLKS VPPPDFGTPT LHYFEDWGVV TYGSALPAEI NRSFLSFKSG 
KLGGRAIYDI VHRNKYKDWI KGWRNFNAGH EHPDQNSFTF APNGVPFITE ALYGPKYTFF 
NNVLMFSPAV SKSCFSPWVG QVTEDCSSKW SKYKHDLAAS CQGRVVAAEE KNGVVFIRGE 
GVGAYNPQLN LKNVQRNLIL LHPQLLLLVD QIHLGEESPL ETAASFFHNV DVPFEETVVD 
GVHGAFIRQR DGLYKMYWMD DTGYSEKATF ASVTYPRGYP YNGTNYVNVT MHLRSPITRA 
AYLFIGPSID VQSFTVHGDS QQLDVFIATS KHAYATYLWT GEATGQSAFA QVIADRHKIL 
FDRNSAIKSS IVPEVKDYAA IVEQNLQHFK PVFQLLEKQI LSRVRNTASF RKTAERLLRF 
SDKRQTEEAI DRIFAISQQQ QQQSKSKKNR RAGKRYKFVD AVPDIFAQIE VNEKKIRQKA 
QILAQKELPI DEDEEMKDLL DFADVTYEKH KNGGLIKGRF GQARMVTTTH SRAPSLSASY 
TRLFLILNIA IFFVMLAMQL TYFQRAQSLH GQRCLYAVLL IDSCILLWLY SSCSQSQC

Genular Protein ID: 2645704303

Symbol: A0A2R8YE23_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A2R8YE23

Database IDs:

ARBA 7 Antibodypedia 1 Bgee 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 3 GO 1 Gene3D 1 GeneTree 1 HGNC 1 InterPro 2 NCBI Taxonomy 1 PANTHER 2 Proteomes 2 RefSeq 1 SAM 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

Sequence Information:

  • Length: 228
  • Mass: 26097
  • Checksum: C24B72A87257821E
  • Sequence:
    • MRTHTRGAPS VFFIYLLCFV SAYITDENPE VMIPFTNANY DSHPMLYFSR AEVAELQLRA 
ASSHEHIAAR LTEAVHTMLS SPLEYLPPWD PKDYSARWNE IFGNNLGALA MFCVLYPENI 
EARDMAKDYM ERMAAQPSWL VKDAPWDEVP LAHSLVGFAT AYDFLYNYLS KTQQEKFLEV 
IANASGYMYE TSYRRGWGFQ YLHNHQPTNC MALLTGSLVL MNQGMMAA

Genular Protein ID: 2150545341

Symbol: A0A2U3TZJ0_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A2U3TZJ0

Database IDs:

ARBA 7 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 2 ExpressionAtlas 1 GO 1 Gene3D 1 GeneTree 1 HGNC 1 InterPro 3 MassIVE 1 NCBI Taxonomy 1 PANTHER 2 PeptideAtlas 1 Pfam 2 Proteomes 2 RefSeq 1 SAM 1 SMR 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

Sequence Information:

  • Length: 308
  • Mass: 35674
  • Checksum: 25C79D08209EFFC3
  • Sequence:
    • MRTHTRGAPS VFFIYLLCFV SAYITDENPE VMIPFTNANY DSHPMLYFSR AEVAELQLRA 
ASSHEHIAAR LTEAVHTMLS SPLEYLPPWD PKDYSARWNE IFGNNLGALA MFCVLYPENI 
EARDMAKDYM ERMAAQPSWL VKDAPWDEVP LAHSLVGFAT AYDFLYNYLS KTQQEKFLEV 
IANASGYMYE TSYRRGWGFQ YLHNHQPTNC MALLTGSLVL MNQGYLQEAY LWTKQVLTIM 
EKSLVLLREV TDGSLYEGVA YGSYTTRSLF QYMFLVQRHF NINHFGHPWL KQHFAFMYRT 
ILPGMMAA

Genular Protein ID: 2615135044

Symbol: B7Z765_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z765

Database IDs:

ARBA 7 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 1 Gene3D 2 InterPro 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PhylomeDB 1 ProteomicsDB 1 RefSeq 2 SAM 1 SUPFAM 1

Sequence Information:

  • Length: 977
  • Mass: 111824
  • Checksum: A036EF317419C504
  • Sequence:
    • MGSFEDGLAA LEIWRSDATM RTHTRGAPSV FFIYLLCFVS AYITDENPEV MIPFTNANYD 
SHPMLYFSRA EVAELQLRAA SSHEHIAARL TEAVHTMLSS PLEYLPPWDP KDYSARWNEI 
FGNNLGALAM FCVLYPENIE ARDMAKDYME RMAAQPSWLV KDAPWDEVPL AHSLVGFATA 
YDFLYNYLSK TQQEKFLEVI ANASGYMYET SYRRGWGFQY LHNHQPTNCM ALLTGSLVLM 
NQGYLQEAYL WTKQVLTIME KSLVLLREVT DGSLYEGVAY GSYTTRSLFQ YMFLVQRHFN 
INHFGHPWLK QHFAFMYRTI LPGFQRTVAI ADSNYNWFYG PESQLVFLDK FVMRNGSGNW 
LADQIRRNRV VEGPGTPSKG QRWCTLHTEF LWYDGSLKSV PPPDFGTPTL HYFEDWGVVT 
YGSALPAEIN RSFLSFKSGK LGGRAIYDIV HRNKYKDWIK GWRNFNAGHE HPDQNSFTFA 
PNGVPFITEA LYGPKYTFFN NVLMFSPAVS KSCFSPWVGQ VTEDCSSKWS KYKHDLAASC 
QGRVVAAEEK NGVVFIRGEG VGAYNPQLNL KNVQRNLILL HPQLLLLVDQ IHLGEESPLE 
TAASFFHNVD VPFEETVVDG VHGAFIRQRD GLYKMYWMDD TGYSEKATFA SVTYPRGYPY 
NGTNYVNVTM HLRSPITRAA YLFIGPSIDV QSFTVHGDSQ QLDVFIATSK HAYATYLWTG 
EATGQSAFAQ VIADRHKILF DRNSAIKSSI VPEVKDYAAI VEQNLQHFKP VFQLLEKQIL 
SRVRNTASFR KTAERLLRFS DKRQTEEAID RIFAISQQQQ QQSKSKKNRR AGKRYKFVDA 
VPDIFAQIEV NEKKIRQKAQ ILAQKELPID EDEEMKDLLD FADVTYEKHK NGGLIKGRFG 
QARMVTTTHS RAPSLSASYT RLFLILNIAI FFVMLAMQLT YFQRAQSLHG QRCLYAVLLI 
DSCILLWLYS SCSQSQC

Genular Protein ID: 2819260684

Symbol: B7Z1T3_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z1T3

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 NCBI Taxonomy 1 RefSeq 3

Sequence Information:

  • Length: 189
  • Mass: 20040
  • Checksum: 8ADAF479443B6D35
  • Sequence:
    • MAALKGRQVY WATAGKISGW TWPHAPRRPH VLLLNGIGVG GALGSIDELL CQALSNGLNV 
PEGSLTSTCA QQPDGLIHTA KWGHVHSLSS HSPGAPNACG VLPGTTVDDG VHQDLQRVLA 
CEQVYDLEGM LDDAHSHELL AVVAAVHHHG VSKALHNGTL SFVEAFGGIP PCTVRIFRRW 
FGCLGDLEI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.