Details for: TNPO2

Gene ID: 30000

Symbol: TNPO2

Ensembl ID: ENSG00000105576

Description: transportin 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 171.1399
    Cell Significance Index: -26.6200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 108.7748
    Cell Significance Index: -27.5900
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 56.6378
    Cell Significance Index: -26.7400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 23.0503
    Cell Significance Index: -28.4200
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 9.5227
    Cell Significance Index: -25.5100
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 7.3518
    Cell Significance Index: -16.0900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 7.2718
    Cell Significance Index: -28.7000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.4513
    Cell Significance Index: 143.5700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.3484
    Cell Significance Index: 219.3100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.2252
    Cell Significance Index: 34.2400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.1654
    Cell Significance Index: 233.7800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.8506
    Cell Significance Index: 168.8000
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.8111
    Cell Significance Index: 17.7600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.6743
    Cell Significance Index: 241.8600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5749
    Cell Significance Index: 519.1400
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.5643
    Cell Significance Index: 33.8800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.5432
    Cell Significance Index: 14.5600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.4203
    Cell Significance Index: 32.2500
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3812
    Cell Significance Index: 26.3600
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3731
    Cell Significance Index: 10.7500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.3433
    Cell Significance Index: 47.1500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.3186
    Cell Significance Index: 39.1700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.3154
    Cell Significance Index: 56.8600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.2687
    Cell Significance Index: 12.1800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.2534
    Cell Significance Index: 15.9700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.2488
    Cell Significance Index: 5.3900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.2478
    Cell Significance Index: 13.9100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.2317
    Cell Significance Index: 14.2400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.2288
    Cell Significance Index: 101.1800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2263
    Cell Significance Index: 43.0700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1976
    Cell Significance Index: 107.9000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.1611
    Cell Significance Index: 8.4600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.1534
    Cell Significance Index: 7.9700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.1273
    Cell Significance Index: 8.5600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1145
    Cell Significance Index: 4.0300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0702
    Cell Significance Index: 9.0000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0646
    Cell Significance Index: 1.6200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0625
    Cell Significance Index: 117.7500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0610
    Cell Significance Index: 2.8500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.0575
    Cell Significance Index: 2.5500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0566
    Cell Significance Index: 0.9700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0411
    Cell Significance Index: 26.1100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0355
    Cell Significance Index: 65.3800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0328
    Cell Significance Index: 1.5400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0314
    Cell Significance Index: 48.3400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0227
    Cell Significance Index: 3.8700
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0098
    Cell Significance Index: 13.2700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0084
    Cell Significance Index: 3.8100
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0026
    Cell Significance Index: -0.0700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0047
    Cell Significance Index: -0.5400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0072
    Cell Significance Index: -4.5200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0075
    Cell Significance Index: -0.1600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0096
    Cell Significance Index: -7.1300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0140
    Cell Significance Index: -10.2300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0170
    Cell Significance Index: -2.4700
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0174
    Cell Significance Index: -0.3400
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.0224
    Cell Significance Index: -0.6400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0238
    Cell Significance Index: -18.0100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0257
    Cell Significance Index: -0.7000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0355
    Cell Significance Index: -20.0300
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0405
    Cell Significance Index: -1.1600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0409
    Cell Significance Index: -1.5500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0502
    Cell Significance Index: -5.9200
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.0542
    Cell Significance Index: -6.1900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0687
    Cell Significance Index: -8.8800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0705
    Cell Significance Index: -14.8500
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0734
    Cell Significance Index: -5.1900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0783
    Cell Significance Index: -22.5200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0792
    Cell Significance Index: -5.1100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0815
    Cell Significance Index: -8.3300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0886
    Cell Significance Index: -10.3300
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.1063
    Cell Significance Index: -2.2100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1079
    Cell Significance Index: -8.0400
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.1247
    Cell Significance Index: -2.6700
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1249
    Cell Significance Index: -2.0900
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.1266
    Cell Significance Index: -1.5700
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.1480
    Cell Significance Index: -3.5500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.1548
    Cell Significance Index: -5.3800
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.1686
    Cell Significance Index: -2.3000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2258
    Cell Significance Index: -23.5100
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.2330
    Cell Significance Index: -5.9900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2779
    Cell Significance Index: -22.0100
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.2814
    Cell Significance Index: -7.4000
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.4003
    Cell Significance Index: -5.9100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4220
    Cell Significance Index: -25.8700
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.4448
    Cell Significance Index: -9.6100
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.4845
    Cell Significance Index: -15.4300
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.5027
    Cell Significance Index: -16.4600
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.5053
    Cell Significance Index: -12.3300
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.5368
    Cell Significance Index: -8.0900
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.5454
    Cell Significance Index: -10.9500
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.5503
    Cell Significance Index: -11.6800
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.5551
    Cell Significance Index: -14.1800
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: -0.5799
    Cell Significance Index: -4.4700
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.5806
    Cell Significance Index: -20.3400
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.5822
    Cell Significance Index: -6.9400
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.6113
    Cell Significance Index: -22.4400
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.6195
    Cell Significance Index: -12.2500
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.6213
    Cell Significance Index: -16.6200
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.6289
    Cell Significance Index: -6.5100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** TNPO2 is a member of the importin β family of proteins, which are known for their ability to bind to nuclear localization signals (NLS) and facilitate the nuclear import of proteins. TNPO2 is characterized by its high degree of sequence similarity to other importins, particularly Importin α, and has been shown to bind to a wide range of NLS-containing proteins. TNPO2 is predominantly expressed in neurons and has been implicated in the regulation of various cellular processes, including transcription, translation, and cell cycle progression. **Pathways and Functions:** TNPO2 has been shown to play a critical role in the regulation of neuronal function and development through its involvement in several key pathways. These include: 1. **Nuclear Import:** TNPO2 facilitates the nuclear import of proteins, including transcription factors, which are essential for the regulation of gene expression in neurons. 2. **Cell Cycle Regulation:** TNPO2 has been shown to regulate the cell cycle in neurons, ensuring proper cell proliferation and differentiation. 3. **Neurotransmission:** TNPO2 has been implicated in the regulation of neurotransmitter release and uptake, which is critical for normal neuronal function. 4. **Synaptic Plasticity:** TNPO2 has been shown to regulate synaptic plasticity, which is essential for learning and memory. **Clinical Significance:** Dysregulation of TNPO2 has been implicated in various neurological disorders, including: 1. **Neurodegenerative Diseases:** TNPO2 has been shown to be involved in the pathogenesis of neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and Huntington's disease. 2. **Neurodevelopmental Disorders:** TNPO2 has been implicated in the regulation of neuronal development and function, and dysregulation of TNPO2 has been associated with neurodevelopmental disorders such as autism spectrum disorder and schizophrenia. 3. **Cancer:** TNPO2 has been shown to be involved in the regulation of cell cycle and proliferation in cancer cells, and has been implicated in the development of various types of cancer. In conclusion, TNPO2 plays a critical role in the regulation of neuronal function and development, and dysregulation of TNPO2 has been implicated in various neurological disorders. Further research is needed to fully understand the mechanisms by which TNPO2 regulates neuronal function and to identify potential therapeutic targets for the treatment of neurodegenerative and neurodevelopmental disorders.

Genular Protein ID: 665648692

Symbol: TNPO2_HUMAN

Name: Transportin-2

UniProtKB Accession Codes:

O14787 O14655 Q6IN77

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CORUM 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 5 Ensembl 5 ExpressionAtlas 1 GO 6 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 RefSeq 3 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9298975

Title: Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins.

PubMed ID: 9298975

DOI: 10.1083/jcb.138.6.1181

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23033978

Title: Diagnostic exome sequencing in persons with severe intellectual disability.

PubMed ID: 23033978

DOI: 10.1056/nejmoa1206524

PubMed ID: 34314705

Title: TNPO2 variants associate with human developmental delays, neurologic deficits, and dysmorphic features and alter TNPO2 activity in Drosophila.

PubMed ID: 34314705

DOI: 10.1016/j.ajhg.2021.06.019

Sequence Information:

  • Length: 897
  • Mass: 101388
  • Checksum: 26FE455583D7D35F
  • Sequence:
    • MDWQPDEQGL QQVLQLLKDS QSPNTATQRI VQDKLKQLNQ FPDFNNYLIF VLTRLKSEDE 
PTRSLSGLIL KNNVKAHYQS FPPPVADFIK QECLNNIGDA SSLIRATIGI LITTIASKGE 
LQMWPELLPQ LCNLLNSEDY NTCEGAFGAL QKICEDSSEL LDSDALNRPL NIMIPKFLQF 
FKHCSPKIRS HAIACVNQFI MDRAQALMDN IDTFIEHLFA LAVDDDPEVR KNVCRALVML 
LEVRIDRLIP HMHSIIQYML QRTQDHDENV ALEACEFWLT LAEQPICKEV LASHLVQLIP 
ILVNGMKYSE IDIILLKGDV EEDEAVPDSE QDIKPRFHKS RTVTLPHEAE RPDGSEDAED 
DDDDDALSDW NLRKCSAAAL DVLANVFREE LLPHLLPLLK GLLFHPEWVV KESGILVLGA 
IAEGCMQGMV PYLPELIPHL IQCLSDKKAL VRSIACWTLS RYAHWVVSQP PDMHLKPLMT 
ELLKRILDGN KRVQEAACSA FATLEEEACT ELVPYLSYIL DTLVFAFGKY QHKNLLILYD 
AIGTLADSVG HHLNQPEYIQ KLMPPLIQKW NELKDEDKDL FPLLECLSSV ATALQSGFLP 
YCEPVYQRCV TLVQKTLAQA MMYTQHPEQY EAPDKDFMIV ALDLLSGLAE GLGGHVEQLV 
ARSNIMTLLF QCMQDSMPEV RQSSFALLGD LTKACFIHVK PCIAEFMPIL GTNLNPEFIS 
VCNNATWAIG EICMQMGAEM QPYVQMVLNN LVEIINRPNT PKTLLENTGR LTSPSAIPAI 
TIGRLGYVCP QEVAPMLQQF IRPWCTSLRN IRDNEEKDSA FRGICMMIGV NPGGVVQDFI 
FFCDAVASWV SPKDDLRDMF YKILHGFKDQ VGEDNWQQFS EQFPPLLKER LAAFYGV

Genular Protein ID: 1211526439

Symbol: Q05D48_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q05D48

Database IDs:

ARBA 3 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 6 Gene3D 1 InterPro 5 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 3 PharmGKB 1 RefSeq 1 SAM 1 SMART 2 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 771
  • Mass: 87140
  • Checksum: 89C1980212414ACE
  • Sequence:
    • MDWQPDEQGL QQVLQLLKDS QSPNTATQRI VQDKLKQLNQ FPDFNNYLIF VLTRLKSEDE 
PTRSLSGLIL KNNVKAHYQS FPPPVADFIK QECLNNIGDA SSLIRATIGI LITTIASKGE 
LQMWPELLPQ LCNLLNSEDY NTCEGAFGAL QKICEDSSEL LDSDALNRPL NIMIPKFLQF 
FKHCSPKIRS HAIACVNQFI MDRAQALMDN IDTFIEHLFA LAVDDDPEVR KNVCRALVML 
LEVRIDRLIP HMHSIIQYML QRTQDHDENV ALEACEFWLT LAEQPICKEV LASHLVQLIP 
ILVNGMKYSE IDIILLKGDV EEDEAVPDSE QDIKPRFHKS RTVTLPHEAE RPDGSEDAED 
DDDDDALSDW NLRKCSAAAL DVLANVFREE LLPHLLPLLK GLLFHPEWVV KESGILVLGA 
IAEGCMQGMV PYLPELIPHL IQCLSDKKAL VRSIACWTLS RYAHWVVSQP PDMHLKPLMT 
ELLKRILDGN KRVQEAACSA FATLEEEACT ELVPYLSYIL DTLVFAFGKY QHKNLLILYD 
AIGTLADSVG HHLNQPEYIQ KLMPPLIQKW NELKDEDKDL FPLLECLSSV ATALQSGFLP 
YCEPVYQRCV TLVQKTLAQA MMYTQHPEQY EAPDKDFMIV ALDLLSGLAE GLGGHVEQLV 
ARSNIMTLLF QCMQDSMPEV RQSSFALLGD LTKACFIHVK PCIAEFMPIL GTNLNPEFIS 
VCNNATWAIG EICMQMGAEM QPYVQMVLNN LVEIINRPTP TQEQGLKKKK K

Genular Protein ID: 147066425

Symbol: Q4LE60_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q4LE60

Database IDs:

ARBA 3 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 6 Gene3D 1 IntAct 1 InterPro 5 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 Pfam 3 PharmGKB 1 PhylomeDB 1 ProteomicsDB 1 RefSeq 2 SAM 1 SMART 2 SUPFAM 1

Sequence Information:

  • Length: 1051
  • Mass: 117677
  • Checksum: B218671A44A90AD2
  • Sequence:
    • GQSVGGRGLF RDCACIEETT GAGALSRSGA GPLDVEAAGP SPSRCEGGGS LRARSRGQRH 
GPPWDEGSSL GPMRIRRAPP PPPVARFHIP PPALPSPRLR GRGWRSWRGP RTWAGVDRRP 
PPVRRGRSRR HAATAASGAP PGSHTEPQRP SADPGPYLRS LPCAMDWQPD EQGLQQVLQL 
LKDSQSPNTA TQRIVQDKLK QLNQFPDFNN YLIFVLTRLK SEDEPTRSLS GLILKNNVKA 
HYQSFPPPVA DFIKQECLNN IGDASSLIRA TIGILITTIA SKGELQMWPE LLPQLCNLLN 
SEDYNTCEGA FGALQKICED SSELLDSDAL NRPLNIMIPK FLQFFKHCSP KIRSHAIACV 
NQFIMDRAQA LMDNIDTFIE HLFALAVDDD PEVRKNVCRA LVMLLEVRID RLIPHMHSII 
QYMLQRTQDH DENVALEACE FWLTLAEQPI CKEVLASHLV QLIPILVNGM KYSEIDIILL 
KGDVEEDEAV PDSEQDIKPR FHKSRTVTLP HEAERPDGSE DAEDDDDDDA LSDWNLRKCS 
AAALDVLANV FREELLPHLL PLLKGLLFHP EWVVKESGIL VLGAIAEGCM QGMVPYLPEL 
IPHLIQCLSD KKALVRSIAC WTLSRYAHWV VSQPPDMHLK PLMTELLKRI LDGNKRVQEA 
ACSAFATLEE EACTELVPYL SYILDTLVFA FGKYQHKNLL ILYDAIGTLA DSVGHHLNQP 
EYIQKLMPPL IQKWNELKDE DKDLFPLLEC LSSVATALQS GFLPYCEPVY QRCVTLVQKT 
LAQAMMYTQH PEQYEAPDKD FMIVALDLLS GLAEGLGGHV EQLVARSNIM TLLFQCMQDS 
MPEVRQSSFA LLGDLTKACF IHVKPCIAEF MPILGTNLNP EFISVCNNAT WAIGEICMQM 
GAEMQPYVQM VLNNLVEIIN RPNTPKTLLE NTAITIGRLG YVCPQEVAPM LQQFIRPWCT 
SLRNIRDNEE KDSAFRGICM MIGVNPGGVV QDFIFFCDAV ASWVSPKDDL RDMFYKILHG 
FKDQVGEDNW QQFSEQFPPL LKERLAAFYG V

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.