Details for: HSD17B4

Gene ID: 3295

Symbol: HSD17B4

Ensembl ID: ENSG00000133835

Description: hydroxysteroid 17-beta dehydrogenase 4

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 2.31
    Marker Score: 7565
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 2.1
    Marker Score: 31436
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.97
    Marker Score: 2897
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 1.92
    Marker Score: 4596
  • Cell Name: type II pneumocyte (CL0002063)
    Fold Change: 1.89
    Marker Score: 12334
  • Cell Name: pneumocyte (CL0000322)
    Fold Change: 1.89
    Marker Score: 3032
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.88
    Marker Score: 7264
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 1.85
    Marker Score: 7689
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 1.85
    Marker Score: 70346
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 1.83
    Marker Score: 14016
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 1.81
    Marker Score: 66650
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.78
    Marker Score: 16721
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.77
    Marker Score: 7217
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 1.77
    Marker Score: 35114
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.75
    Marker Score: 107665
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.73
    Marker Score: 11101
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.72
    Marker Score: 16338
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 1.71
    Marker Score: 1187
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 1.7
    Marker Score: 9164
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.7
    Marker Score: 27361
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: 1.67
    Marker Score: 2653
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 1.65
    Marker Score: 6899
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 1.65
    Marker Score: 983
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.64
    Marker Score: 1724
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.63
    Marker Score: 13986
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 1.61
    Marker Score: 6947
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 1.61
    Marker Score: 35939
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.59
    Marker Score: 16460
  • Cell Name: fat cell (CL0000136)
    Fold Change: 1.59
    Marker Score: 889
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 1.59
    Marker Score: 33899
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.54
    Marker Score: 2370
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 1.53
    Marker Score: 4106
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 1.5
    Marker Score: 6950
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: 1.48
    Marker Score: 5746
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.48
    Marker Score: 26203
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: 1.45
    Marker Score: 37172
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 1.43
    Marker Score: 1272
  • Cell Name: oogonial cell (CL0000024)
    Fold Change: 1.43
    Marker Score: 2059
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 1.42
    Marker Score: 3108.5
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 1.4
    Marker Score: 2483
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.4
    Marker Score: 3189
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 1.4
    Marker Score: 1610
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: 1.38
    Marker Score: 3489
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 1.38
    Marker Score: 668
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 1.34
    Marker Score: 502
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 1.33
    Marker Score: 5541
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: 1.32
    Marker Score: 380
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 1.31
    Marker Score: 383
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.31
    Marker Score: 647
  • Cell Name: subcutaneous fat cell (CL0002521)
    Fold Change: 1.3
    Marker Score: 477
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 1.29
    Marker Score: 1229
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.28
    Marker Score: 5015
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 1.27
    Marker Score: 1101
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 1.25
    Marker Score: 1330
  • Cell Name: kidney collecting duct intercalated cell (CL1001432)
    Fold Change: 1.25
    Marker Score: 2066
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 1.23
    Marker Score: 820
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 1.21
    Marker Score: 383
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 1.21
    Marker Score: 2327.5
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: 1.2
    Marker Score: 10364
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 1.2
    Marker Score: 2525
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 1.19
    Marker Score: 1262
  • Cell Name: enterocyte (CL0000584)
    Fold Change: 1.19
    Marker Score: 5718
  • Cell Name: respiratory epithelial cell (CL0002368)
    Fold Change: 1.19
    Marker Score: 655
  • Cell Name: lung macrophage (CL1001603)
    Fold Change: 1.18
    Marker Score: 1353
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 1.18
    Marker Score: 983
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.16
    Marker Score: 1317
  • Cell Name: basal cell (CL0000646)
    Fold Change: 1.16
    Marker Score: 1491
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 1.15
    Marker Score: 1425
  • Cell Name: primordial germ cell (CL0000670)
    Fold Change: 1.15
    Marker Score: 1443
  • Cell Name: bronchial goblet cell (CL1000312)
    Fold Change: 1.14
    Marker Score: 563
  • Cell Name: epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 1.14
    Marker Score: 510
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: 1.13
    Marker Score: 530
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 1.13
    Marker Score: 980
  • Cell Name: stem cell (CL0000034)
    Fold Change: 1.12
    Marker Score: 2670
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 1.12
    Marker Score: 619
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 1.12
    Marker Score: 766.5
  • Cell Name: nephron tubule epithelial cell (CL1000494)
    Fold Change: 1.11
    Marker Score: 261
  • Cell Name: club cell (CL0000158)
    Fold Change: 1.11
    Marker Score: 1296.5
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 1.11
    Marker Score: 751
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 1.11
    Marker Score: 644
  • Cell Name: paneth cell (CL0000510)
    Fold Change: 1.1
    Marker Score: 762
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 1.09
    Marker Score: 8133
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 1.09
    Marker Score: 36893
  • Cell Name: colon epithelial cell (CL0011108)
    Fold Change: 1.09
    Marker Score: 3419
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.08
    Marker Score: 37471.5
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 1.08
    Marker Score: 1530
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 1.08
    Marker Score: 3838
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.07
    Marker Score: 16746
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 1.07
    Marker Score: 1068.5
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 1.07
    Marker Score: 980
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: 1.06
    Marker Score: 263
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 1.06
    Marker Score: 245
  • Cell Name: papillary tips cell (CL1000597)
    Fold Change: 1.06
    Marker Score: 214
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.06
    Marker Score: 11930
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 1.06
    Marker Score: 2873
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 1.05
    Marker Score: 1094
  • Cell Name: epithelial cell of lung (CL0000082)
    Fold Change: 1.05
    Marker Score: 5519
  • Cell Name: elicited macrophage (CL0000861)
    Fold Change: 1.05
    Marker Score: 6355
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 1.04
    Marker Score: 693
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 1.04
    Marker Score: 607

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Other Information

**Key characteristics:** * DHB4 is a multi-functional enzyme that performs various functions in steroid metabolism. * It is involved in the production of bile acids and bile salts, which are essential for the digestion and absorption of fats. * It also plays a role in the metabolism of fatty acids, cholesterol, and other lipids. **Pathways and functions:** * DHB4 is involved in the 3-hydroxyacyl-CoA dehydrogenase activity, alpha-linolenic (omega3) and linoleic (omega6) acid metabolism, alpha-linolenic acid (ala) metabolism, beta-oxidation of pristanoyl-CoA, beta-oxidation of very long chain fatty acids, bile acid and bile salt metabolism, and peroxisomal protein import. * It is also involved in the synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol. * DHB4 is a key regulator of bile acid metabolism, and its activity can be altered by various factors, including diet, exercise, and genetic variations. **Clinical significance:** * Mutations in the HSD17B4 gene have been linked to several human diseases, including cholestatic liver disease, gallbladder disease, and bile duct stones. * Drug-induced HSD17B4 inhibition can lead to hypercholesterolemia, a condition in which the blood contains too much cholesterol. * Therefore, understanding the role of HSD17B4 in steroid metabolism may lead to the development of new therapies for these diseases.

Genular Protein ID: 1709670036

Symbol: DHB4_HUMAN

Name: 17-beta-hydroxysteroid dehydrogenase 4

UniProtKB Accession Codes:

P51659 B4DNV1 B4DVS5 E9PB82 F5HE57

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 2 CPTAC 2 CTD 1 ChEBI 60 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 2 EC 3 EMBL 26 EPD 1 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 22 Gene3D 4 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 5 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 3 OrthoDB 1 PANTHER 2 PDB 10 PDBsum 7 PIR 1 PRINTS 2 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 6 RefSeq 5 Rhea 24 SABIO-RK 1 SASBDB 1 SMART 1 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 SwissLipids 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 1 UniPathway 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7487879

Title: Molecular cloning of a novel widely expressed human 80 kDa 17 beta-hydroxysteroid dehydrogenase IV.

PubMed ID: 7487879

DOI: 10.1042/bj3110437

PubMed ID: 9089413

Title: Structure of D-3-hydroxyacyl-CoA dehydratase/D-3-hydroxyacyl-CoA dehydrogenase bifunctional protein.

PubMed ID: 9089413

DOI: 10.1093/oxfordjournals.jbchem.a021596

PubMed ID: 9880674

Title: Structure of the gene for the human 17beta-hydroxysteroid dehydrogenase type IV.

PubMed ID: 9880674

DOI: 10.1007/s003359900921

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8902629

Title: Purification and properties of human D-3-hydroxyacyl-CoA dehydratase: medium-chain enoyl-CoA hydratase is D-3-hydroxyacyl-CoA dehydratase.

PubMed ID: 8902629

DOI: 10.1093/oxfordjournals.jbchem.a021458

PubMed ID: 10671535

Title: Human peroxisomal multifunctional enzyme type 2. Site-directed mutagenesis studies show the importance of two protic residues for 2-enoyl-CoA hydratase 2 activity.

PubMed ID: 10671535

DOI: 10.1074/jbc.275.7.4965

PubMed ID: 10706581

Title: Peroxisomal fatty acid oxidation disorders and 58 kDa sterol carrier protein X (SCPx). Activity measurements in liver and fibroblasts using a newly developed method.

PubMed ID: 10706581

PubMed ID: 15060085

Title: Identification of the peroxisomal beta-oxidation enzymes involved in the degradation of long-chain dicarboxylic acids.

PubMed ID: 15060085

DOI: 10.1194/jlr.m300512-jlr200

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 11700068

Title: Crystal structure of the liganded SCP-2-like domain of human peroxisomal multifunctional enzyme type 2 at 1.75 A resolution.

PubMed ID: 11700068

DOI: 10.1006/jmbi.2001.5084

PubMed ID: 15644212

Title: Crystal structure of 2-enoyl-CoA hydratase 2 from human peroxisomal multifunctional enzyme type 2.

PubMed ID: 15644212

DOI: 10.1016/j.jmb.2004.11.009

PubMed ID: 9482850

Title: Peroxisomal D-hydroxyacyl-CoA dehydrogenase deficiency: resolution of the enzyme defect and its molecular basis in bifunctional protein deficiency.

PubMed ID: 9482850

DOI: 10.1073/pnas.95.5.2128

PubMed ID: 10400999

Title: Enoyl-CoA hydratase deficiency: identification of a new type of D-bifunctional protein deficiency.

PubMed ID: 10400999

DOI: 10.1093/hmg/8.8.1509

PubMed ID: 11743515

Title: D-bifunctional protein deficiency with fetal ascites, polyhydramnios, and contractures of hands and toes.

PubMed ID: 11743515

DOI: 10.1067/mpd.2001.119170

PubMed ID: 20673864

Title: Mutations in the DBP-deficiency protein HSD17B4 cause ovarian dysgenesis, hearing loss, and ataxia of Perrault Syndrome.

PubMed ID: 20673864

DOI: 10.1016/j.ajhg.2010.07.007

PubMed ID: 25956234

Title: Exome analysis identified a novel missense mutation in the CLPP gene in a consanguineous Saudi family expanding the clinical spectrum of Perrault Syndrome type-3.

PubMed ID: 25956234

DOI: 10.1016/j.jns.2015.04.038

Sequence Information:

  • Length: 736
  • Mass: 79686
  • Checksum: 7B11E02483328BCE
  • Sequence:
    • MGSPLRFDGR VVLVTGAGAG LGRAYALAFA ERGALVVVND LGGDFKGVGK GSLAADKVVE 
EIRRRGGKAV ANYDSVEEGE KVVKTALDAF GRIDVVVNNA GILRDRSFAR ISDEDWDIIH 
RVHLRGSFQV TRAAWEHMKK QKYGRIIMTS SASGIYGNFG QANYSAAKLG LLGLANSLAI 
EGRKSNIHCN TIAPNAGSRM TQTVMPEDLV EALKPEYVAP LVLWLCHESC EENGGLFEVG 
AGWIGKLRWE RTLGAIVRQK NHPMTPEAVK ANWKKICDFE NASKPQSIQE STGSIIEVLS 
KIDSEGGVSA NHTSRATSTA TSGFAGAIGQ KLPPFSYAYT ELEAIMYALG VGASIKDPKD 
LKFIYEGSSD FSCLPTFGVI IGQKSMMGGG LAEIPGLSIN FAKVLHGEQY LELYKPLPRA 
GKLKCEAVVA DVLDKGSGVV IIMDVYSYSE KELICHNQFS LFLVGSGGFG GKRTSDKVKV 
AVAIPNRPPD AVLTDTTSLN QAALYRLSGD WNPLHIDPNF ASLAGFDKPI LHGLCTFGFS 
ARRVLQQFAD NDVSRFKAIK ARFAKPVYPG QTLQTEMWKE GNRIHFQTKV QETGDIVISN 
AYVDLAPTSG TSAKTPSEGG KLQSTFVFEE IGRRLKDIGP EVVKKVNAVF EWHITKGGNI 
GAKWTIDLKS GSGKVYQGPA KGAADTTIIL SDEDFMEVVL GKLDPQKAFF SGRLKARGNI 
MLSQKLQMIL KDYAKL

Genular Protein ID: 3560650955

Symbol: B2R659_HUMAN

Name: N/A

UniProtKB Accession Codes:

B2R659

Database IDs:

ARBA 6 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 EMBL 2 GO 3 Gene3D 4 Genevisible 1 GenomeRNAi 1 InterPro 7 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 1 PeptideAtlas 1 Pfam 5 RefSeq 4 SMART 1 SUPFAM 3 UniPathway 1

Sequence Information:

  • Length: 736
  • Mass: 79612
  • Checksum: 1DFFAE2214257B9E
  • Sequence:
    • MGSPLRFDGR VVLVTGAGAG LGRAYALAFA ERGALVVVND LGGDFKGVGK GSLAADKVVE 
EIRRRGGKAV ANYDSVEEGE KVVKTALDAF GRIDVVVNNA GILRDRSFAR ISDEDWDIIH 
RVHLRGSFQV TRAAWEHMKK QKYGRIIMTS SASGIYGNFG QANYSAAKLG LLGLANSLAI 
EGRKSNIHCN TIAPNAGSRM TQTVTPEDLV EALKPEYVAP LVLWLCHESC EENGGLFEVG 
AGWIGKLRWE RTLGAIVRQK NHPMTPEAVK ANWKKICDFE NASKPQSIQE STGSIIEVLS 
KIDSEGGVSA NHTSRATSTA TSGFAGAIGQ KLPPFSYAYT ELEAIMYALG VGASIKDPKD 
LKFIYEGSSD FSCLPTFGVI IGQKSMMGGG LAEIPGLSIN FAKVLHGEQY LELYKPLPRA 
GKLKCEAVVA DVLDKGSGVV IIMDVYSYSE KELICHNQFS LFLVGSGGFG GKRTSDKVKV 
AVAIPNRPPD AVLTDTTSLN QAALYRLSGD RNPLHIDPNF ASLAGFDKPI LHGLCTFGFS 
ARRVLQQFAD NDVSRFKAVK ARFAKPVYPG QTLQTEMWKE GNRIHFQTKV QETGDIVISN 
AYVDLAPTSG TSAKTPSEGG KLQSTFVFEE IGRRLKDIGP EVVKKVNAVF EWHITKGGNI 
GAKWTIDLKS GSGKVYQGPA KGAADTTIIL SDEDFMEVVL GKLDPQKAFF SGRLKARGNI 
MLSQKLQMIL KDYAKL

Genular Protein ID: 2675507292

Symbol: B3KSP2_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KSP2

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 EMBL 2 GO 3 Gene3D 4 GenomeRNAi 1 InterPro 7 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 1 PeptideAtlas 1 Pfam 5 RefSeq 1 SUPFAM 3 UniPathway 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 596
  • Mass: 64592
  • Checksum: 187FDF6AEF006596
  • Sequence:
    • MKKQKIIMTS SASGIYGNFG QANYSAAKLG LLGLANSLAI EGRKSNIHCN TIAPNAGSRM 
TQTVMPEDLV EALKPEYVAP LVLWLCHESC EENGGLFEVG AGWIGKLRWE RTLGAIVRQK 
NHPMTPEAVK ANWKKICDFE NASKPQSIQE STGSIIEVLS KIDSEGGVSA NHTSRATSTA 
TSGFAGAIGQ KLPPFSYAYT ELEAIMYALG VGASIKDPKD LKFIYEGSSD FSCLPTFGVI 
IGQKSMMGGG LAEIPGLSIN FAKVLHGEQY LELYKPLPRA GKLKCEAVVA DVLDKGSGVV 
IIMDVYSYSE KELICHNQFS LFLVGSGGFG GKRTSDKVKV AVAIPNRPPD AVLTDTTSLN 
QAALYRLSGD WNPLHIDPNF ASLAGFDKPI LHGLCTFGFS ARRVLQQFAD NDVSRFKAIK 
ARFAKPVYPG QTLQTEMWKE GNRIHFQTKV QETGDIVISN AYVDLAPTSG TSAKTPSEGG 
KLQSTFVFEE IGRRLKDIGP EVVKKVNAVF EWHITKGGNI GAKWTIDLKS GSGKVYQGPA 
KGAADTTIIL SDENFMEVVL GKLDPQKAFF SGRLKARGNI MLSQKLQMIL KDYAKL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.