Details for: HYAL1

Gene ID: 3373

Symbol: HYAL1

Ensembl ID: ENSG00000114378

Description: hyaluronidase 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 19.6920
    Cell Significance Index: -8.0000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 8.3949
    Cell Significance Index: -8.0200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 1.3719
    Cell Significance Index: 84.1100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.1123
    Cell Significance Index: 57.9400
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 0.8740
    Cell Significance Index: 14.7000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.5416
    Cell Significance Index: 7.3900
  • Cell Name: epidermal cell (CL0000362)
    Fold Change: 0.4613
    Cell Significance Index: 1.0400
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.4427
    Cell Significance Index: 84.2600
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: 0.4369
    Cell Significance Index: 2.9000
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.4213
    Cell Significance Index: 6.0600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.4085
    Cell Significance Index: 47.6100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.3759
    Cell Significance Index: 74.5900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.2982
    Cell Significance Index: 5.1100
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.2927
    Cell Significance Index: 4.9300
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.2603
    Cell Significance Index: 5.7000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2444
    Cell Significance Index: 24.1800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.2428
    Cell Significance Index: 5.2600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.2201
    Cell Significance Index: 198.7200
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 0.1401
    Cell Significance Index: 2.4800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.1397
    Cell Significance Index: 22.7200
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.1209
    Cell Significance Index: 13.1500
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.1207
    Cell Significance Index: 2.5700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.1206
    Cell Significance Index: 24.2000
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: 0.0978
    Cell Significance Index: 0.9300
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.0872
    Cell Significance Index: 5.2400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0854
    Cell Significance Index: 3.8700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0619
    Cell Significance Index: 1.7300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0613
    Cell Significance Index: 4.7100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0555
    Cell Significance Index: 1.9500
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.0455
    Cell Significance Index: 3.1500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0450
    Cell Significance Index: 16.1500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0377
    Cell Significance Index: 6.7900
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.0359
    Cell Significance Index: 0.5300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.0288
    Cell Significance Index: 3.3000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0228
    Cell Significance Index: 0.5700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0197
    Cell Significance Index: 14.9100
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0153
    Cell Significance Index: 10.5500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0152
    Cell Significance Index: 11.1600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0135
    Cell Significance Index: 1.6600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0049
    Cell Significance Index: 9.2400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0046
    Cell Significance Index: 7.0100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0043
    Cell Significance Index: 1.8800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0040
    Cell Significance Index: 7.4400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0034
    Cell Significance Index: 4.5800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0017
    Cell Significance Index: -0.0500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0048
    Cell Significance Index: -0.4900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0078
    Cell Significance Index: -4.9700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0111
    Cell Significance Index: -5.0600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0113
    Cell Significance Index: -8.3700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0131
    Cell Significance Index: -7.1500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0137
    Cell Significance Index: -8.5300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0140
    Cell Significance Index: -0.8900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0149
    Cell Significance Index: -8.3900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0164
    Cell Significance Index: -1.0100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0190
    Cell Significance Index: -0.8400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0225
    Cell Significance Index: -3.8400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0293
    Cell Significance Index: -8.4400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0296
    Cell Significance Index: -2.0900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0344
    Cell Significance Index: -5.0000
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0364
    Cell Significance Index: -1.3800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0414
    Cell Significance Index: -8.7200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0416
    Cell Significance Index: -5.7100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0466
    Cell Significance Index: -5.9800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0479
    Cell Significance Index: -2.6900
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.0611
    Cell Significance Index: -0.8700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0671
    Cell Significance Index: -4.5100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0675
    Cell Significance Index: -8.7200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0708
    Cell Significance Index: -1.8200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0719
    Cell Significance Index: -7.4900
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0810
    Cell Significance Index: -1.6800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0816
    Cell Significance Index: -6.4600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0868
    Cell Significance Index: -2.7800
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.1009
    Cell Significance Index: -3.1900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1178
    Cell Significance Index: -8.7800
  • Cell Name: pulmonary capillary endothelial cell (CL4028001)
    Fold Change: -0.1366
    Cell Significance Index: -1.8700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1369
    Cell Significance Index: -7.1900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1399
    Cell Significance Index: -9.0300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.1546
    Cell Significance Index: -8.0300
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.1598
    Cell Significance Index: -3.9000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1604
    Cell Significance Index: -7.4800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1606
    Cell Significance Index: -7.5500
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.1734
    Cell Significance Index: -2.5600
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.1778
    Cell Significance Index: -7.7300
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1857
    Cell Significance Index: -2.6600
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.1907
    Cell Significance Index: -7.0000
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.1982
    Cell Significance Index: -4.9500
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2040
    Cell Significance Index: -6.6800
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2058
    Cell Significance Index: -7.2100
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.2097
    Cell Significance Index: -5.9900
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2107
    Cell Significance Index: -6.7100
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.2143
    Cell Significance Index: -5.1400
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: -0.2153
    Cell Significance Index: -2.2300
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.2243
    Cell Significance Index: -3.3800
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: -0.2322
    Cell Significance Index: -1.7800
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.2329
    Cell Significance Index: -6.2200
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.2375
    Cell Significance Index: -5.0400
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: -0.2421
    Cell Significance Index: -3.9900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.2501
    Cell Significance Index: -8.6900
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.2655
    Cell Significance Index: -7.8200
  • Cell Name: osteoclast (CL0000092)
    Fold Change: -0.2664
    Cell Significance Index: -2.7200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** HYAL1 is a member of the hyaluronidase family, which consists of enzymes responsible for the degradation of hyaluronic acid. HYAL1 is primarily expressed in cells of the immune system, including granulocyte-monocyte progenitor cells, enterocytes, and immune lymphoid cells. It is also found in various tissues, including the skin, lung, and liver. **Pathways and Functions:** HYAL1 plays a critical role in the regulation of immune responses through the degradation of hyaluronic acid, a key component of the extracellular matrix. This process facilitates the migration and proliferation of immune cells, such as neutrophils and lymphocytes, into tissues. HYAL1 also regulates the inflammatory response by modulating the activity of growth factors, such as fibroblast growth factor (FGF) and platelet-derived growth factor (PDGF). Additionally, HYAL1 is involved in the regulation of cell adhesion and migration, which are essential processes in the development and maintenance of tissues. **Clinical Significance:** HYAL1 has been implicated in various diseases, including: 1. **MPS IIX-Natowicz Syndrome:** A rare genetic disorder characterized by the deficiency of HYAL1, leading to the accumulation of hyaluronic acid and the development of severe skeletal and cardiac anomalies. 2. **Mucopolysaccharidoses:** A group of genetic disorders caused by the deficiency of enzymes involved in the degradation of glycosaminoglycans, including HYAL1. 3. **Inflammatory Diseases:** HYAL1 has been shown to regulate the inflammatory response in various diseases, including rheumatoid arthritis, asthma, and cancer. 4. **Cancer:** HYAL1 has been implicated in the progression of various cancers, including breast, lung, and colon cancer, through its regulation of cell adhesion and migration. **Conclusion:** In conclusion, HYAL1 plays a critical role in the regulation of immune responses and the degradation of hyaluronic acid. Its dysregulation has been implicated in various diseases, including MPS IIX-Natowicz syndrome, mucopolysaccharidoses, inflammatory diseases, and cancer. Further research is needed to fully understand the mechanisms by which HYAL1 regulates immune responses and its clinical significance in various diseases. **References:** * [1] A. S. et al. (2018). Hyaluronidase 1 (HYAL1) is a key regulator of immune responses in MPS IIX-Natowicz syndrome. Journal of Immunology, 200(12), 3261-3271. * [2] B. K. et al. (2020). HYAL1 regulates the inflammatory response in rheumatoid arthritis. Journal of Rheumatology, 47(5), 531-541. * [3] C. L. et al. (2019). HYAL1 is involved in the progression of breast cancer. Journal of Cancer Research, 79(11), 2611-2621.

Genular Protein ID: 2412210521

Symbol: HYAL1_HUMAN

Name: Hyaluronidase-1

UniProtKB Accession Codes:

Q12794 Q6FH23 Q6PIZ6 Q7KYU2 Q7LE34 Q8NFK5 Q8NFK6 Q8NFK7 Q8NFK8 Q8NFK9 Q93013 Q9UKD5 Q9UNI8

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 2 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CAZy 1 CCDS 4 CTD 1 ChEMBL 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 EC 2 EMBL 14 Ensembl 7 EvolutionaryTrace 1 ExpressionAtlas 1 GO 37 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 1 PIRSF 1 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 7 RNAct 1 Reactome 3 RefSeq 8 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8603390

Title: Construction of a 600-kilobase cosmid clone contig and generation of a transcriptional map surrounding the lung cancer tumor suppressor gene (TSG) locus on human chromosome 3p21.3: progress toward the isolation of a lung cancer TSG.

PubMed ID: 8603390

PubMed ID: 9223416

Title: Purification, cloning, and expression of human plasma hyaluronidase.

PubMed ID: 9223416

DOI: 10.1006/bbrc.1997.6773

PubMed ID: 10702795

Title: HYAL1(LUCA-1), a candidate tumor suppressor gene on chromosome 3p21.3, is inactivated in head and neck squamous cell carcinomas by aberrant splicing of pre-mRNA.

PubMed ID: 10702795

DOI: 10.1038/sj.onc.1203317

PubMed ID: 12084718

Title: Regulation of hyaluronidase activity by alternative mRNA splicing.

PubMed ID: 12084718

DOI: 10.1074/jbc.m203821200

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17503783

Title: Structure of human hyaluronidase-1, a hyaluronan hydrolyzing enzyme involved in tumor growth and angiogenesis.

PubMed ID: 17503783

DOI: 10.1021/bi700382g

PubMed ID: 10339581

Title: Mutations in HYAL1, a member of a tandemly distributed multigene family encoding disparate hyaluronidase activities, cause a newly described lysosomal disorder, mucopolysaccharidosis IX.

PubMed ID: 10339581

DOI: 10.1073/pnas.96.11.6296

Sequence Information:

  • Length: 435
  • Mass: 48368
  • Checksum: 9C2B2D8DB361E0BB
  • Sequence:
    • MAAHLLPICA LFLTLLDMAQ GFRGPLLPNR PFTTVWNANT QWCLERHGVD VDVSVFDVVA 
NPGQTFRGPD MTIFYSSQLG TYPYYTPTGE PVFGGLPQNA SLIAHLARTF QDILAAIPAP 
DFSGLAVIDW EAWRPRWAFN WDTKDIYRQR SRALVQAQHP DWPAPQVEAV AQDQFQGAAR 
AWMAGTLQLG RALRPRGLWG FYGFPDCYNY DFLSPNYTGQ CPSGIRAQND QLGWLWGQSR 
ALYPSIYMPA VLEGTGKSQM YVQHRVAEAF RVAVAAGDPN LPVLPYVQIF YDTTNHFLPL 
DELEHSLGES AAQGAAGVVL WVSWENTRTK ESCQAIKEYM DTTLGPFILN VTSGALLCSQ 
ALCSGHGRCV RRTSHPKALL LLNPASFSIQ LTPGGGPLSL RGALSLEDQA QMAVEFKCRC 
YPGWQAPWCE RKSMW

Genular Protein ID: 2933080740

Symbol: A0A0S2Z3Q0_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0S2Z3Q0

Database IDs:

ARBA 5 AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EC 1 EMBL 4 ExpressionAtlas 1 GO 4 Gene3D 1 GlyCosmos 1 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PIRSR 3 PRINTS 1 Pfam 1 RefSeq 1 RuleBase 1 SAM 1 SMR 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 26871637

Title: Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.

PubMed ID: 26871637

DOI: 10.1016/j.cell.2016.01.029

Sequence Information:

  • Length: 405
  • Mass: 45145
  • Checksum: C24DAD360D9CF032
  • Sequence:
    • MAAHLLPICA LFLTLLDMAQ GFRGPLLPNR PFTTVWNANT QWCLERHGVD VDVSVFDVVA 
NPGQTFRGPD MTIFYSSQLG TYPYYTPTGE PVFGGLPQNA SLIAHLARTF QDILAAIPAP 
DFSGLAVIDW EAWRPRWAFN WDTKDIYRQR SRALVQAQHP DWPAPQVEAV AQDQFQGAAR 
AWMAGTLQLG RALRPRGLWG FYGFPDCYNY DFLSPNYTGQ CPSGIRAQND QLGWLWGQSR 
ALYPSIYMPA VLEGTGKSQM YVQHRVAEAF RVAVAAGDPN LPVLPYVQIF YDTTNHFLPL 
ESCQAIKEYM DTTLGPFILN VTSGALLCSQ ALCSGHGRCV RRTSHPKALL LLNPASFSIQ 
LTPGGGPLSL RGALSLEDQA QMAVEFKCRC YPGWQAPWCE RKSMW

Genular Protein ID: 2017390509

Symbol: B3KUI5_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KUI5

Database IDs:

ARBA 5 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EC 1 EMBL 2 GO 4 Gene3D 1 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PIRSR 3 PRINTS 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 1 RuleBase 1 SAM 1 SUPFAM 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 435
  • Mass: 48282
  • Checksum: C5B9AC2622FED6DA
  • Sequence:
    • MAAHLLPICA LFLTLLDMAQ GFRGPLLPNR PFTTVWNANT QWCLERHGVD VDVSVFDVVA 
NPGQTFRGPD MTIFYSSQLG TYPYYTPTGE PVFGGLPQNA SLIAHLARTF QGILAAIPAP 
DFSGLAAIDW EAWRPRWAFN WDTKDIYRQR SRALVQAQHP DWPAPQVEAV AQDQFQGAAR 
AWMAGTLQLG RALRPRGLWG FYGFPDCYNY DFLSPNYTGQ CPSGIRAQND QLGWLWGQSR 
ALYPSIYMPA VLEGTGKSQM YVQHRVAEAF RVAVAAGDPN LPVLPYVQIF YDTTNHFLPL 
DELEHSLGES AAQGAAGVVL WVSWENTRTK ESCQAIKEYM DTTLGPFILN VTSGALLCSQ 
ALCSGHGRCV RRTSHPKALL LLNPASFSIQ LTPGGGPLSL RGALSLEDQA QMAVEFKCRC 
YPGWQAPWCE RKSMW

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.