Details for: ITGB5
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 235.8799
Cell Significance Index: -36.6900 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 32.6894
Cell Significance Index: -31.2100 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 13.2506
Cell Significance Index: -29.0000 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 9.2574
Cell Significance Index: -36.5300 - Cell Name: preadipocyte (CL0002334)
Fold Change: 1.9024
Cell Significance Index: 37.1300 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.4601
Cell Significance Index: 289.7600 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.2673
Cell Significance Index: 17.2900 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 1.2572
Cell Significance Index: 146.5100 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: 1.0717
Cell Significance Index: 54.1600 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.9593
Cell Significance Index: 25.6200 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.9353
Cell Significance Index: 101.7400 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.8464
Cell Significance Index: 64.9500 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.5917
Cell Significance Index: 35.5200 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.5904
Cell Significance Index: 16.0700 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.4682
Cell Significance Index: 32.3800 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.4664
Cell Significance Index: 26.1700 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: 0.4636
Cell Significance Index: 3.7800 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.4115
Cell Significance Index: 559.4600 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.3756
Cell Significance Index: 166.0800 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.3711
Cell Significance Index: 10.3700 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.3600
Cell Significance Index: 64.9000 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.3594
Cell Significance Index: 196.2700 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.3543
Cell Significance Index: 16.5200 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.3273
Cell Significance Index: 7.0900 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 0.3212
Cell Significance Index: 5.4100 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.2987
Cell Significance Index: 4.2900 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.2983
Cell Significance Index: 40.9700 - Cell Name: keratocyte (CL0002363)
Fold Change: 0.2786
Cell Significance Index: 4.4200 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.2267
Cell Significance Index: 10.2800 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.1976
Cell Significance Index: 19.5500 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.1935
Cell Significance Index: 23.8000 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1923
Cell Significance Index: 36.5900 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.1682
Cell Significance Index: 4.8500 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.1322
Cell Significance Index: 8.8900 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.1201
Cell Significance Index: 43.0600 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.1176
Cell Significance Index: 181.1100 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.1134
Cell Significance Index: 102.3700 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0866
Cell Significance Index: 159.6200 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0760
Cell Significance Index: 1.9000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0735
Cell Significance Index: 138.4100 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0731
Cell Significance Index: 46.4100 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.0600
Cell Significance Index: 1.7200 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0563
Cell Significance Index: 38.9100 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0384
Cell Significance Index: 4.9200 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0250
Cell Significance Index: 0.8800 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.0209
Cell Significance Index: 1.5600 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.0147
Cell Significance Index: 1.0400 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0014
Cell Significance Index: -1.0100 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0133
Cell Significance Index: -9.8700 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0146
Cell Significance Index: -9.0900 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0288
Cell Significance Index: -4.1900 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: -0.0366
Cell Significance Index: -0.3200 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0474
Cell Significance Index: -21.5000 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0481
Cell Significance Index: -36.3900 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0519
Cell Significance Index: -29.2700 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0603
Cell Significance Index: -10.3000 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.0818
Cell Significance Index: -9.3400 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0998
Cell Significance Index: -20.0200 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1021
Cell Significance Index: -10.4300 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1080
Cell Significance Index: -22.7400 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1155
Cell Significance Index: -33.2400 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1244
Cell Significance Index: -16.0700 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.1506
Cell Significance Index: -0.9100 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.1535
Cell Significance Index: -3.2700 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.1543
Cell Significance Index: -7.2500 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1801
Cell Significance Index: -20.6300 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.1858
Cell Significance Index: -9.6500 - Cell Name: adipocyte of breast (CL0002617)
Fold Change: -0.2462
Cell Significance Index: -3.1000 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.2480
Cell Significance Index: -3.6600 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.3105
Cell Significance Index: -6.4400 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.3112
Cell Significance Index: -8.3300 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.3202
Cell Significance Index: -33.3400 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.3224
Cell Significance Index: -38.0200 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: -0.3595
Cell Significance Index: -5.1700 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.3676
Cell Significance Index: -23.1700 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.3797
Cell Significance Index: -9.7600 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.4030
Cell Significance Index: -31.9200 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: -0.4054
Cell Significance Index: -5.0100 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.4224
Cell Significance Index: -25.9600 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: -0.4476
Cell Significance Index: -6.8100 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.4524
Cell Significance Index: -14.4900 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.5279
Cell Significance Index: -7.5600 - Cell Name: basal cell of epidermis (CL0002187)
Fold Change: -0.5478
Cell Significance Index: -8.3200 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.5609
Cell Significance Index: -36.1900 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.5671
Cell Significance Index: -29.5400 - Cell Name: hepatoblast (CL0005026)
Fold Change: -0.6029
Cell Significance Index: -10.1400 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.6229
Cell Significance Index: -38.1900 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.6326
Cell Significance Index: -9.3400 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.7079
Cell Significance Index: -37.1700 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.7490
Cell Significance Index: -32.5700 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -0.7842
Cell Significance Index: -11.7500 - Cell Name: hippocampal astrocyte (CL0002604)
Fold Change: -0.8088
Cell Significance Index: -11.3100 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.8118
Cell Significance Index: -17.5400 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.8174
Cell Significance Index: -13.6800 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.8431
Cell Significance Index: -30.9500 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.8557
Cell Significance Index: -37.8500 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.8734
Cell Significance Index: -30.3500 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -0.9219
Cell Significance Index: -15.9400 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.9603
Cell Significance Index: -33.6400 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: -0.9691
Cell Significance Index: -8.1400
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 4147502801
Symbol: ITB5_HUMAN
Name: Integrin beta-5
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2328726
Title: Cloning, primary structure and properties of a novel human integrin beta subunit.
PubMed ID: 2328726
PubMed ID: 2371275
Title: Cloning of an integrin beta subunit exhibiting high homology with integrin beta 3 subunit.
PubMed ID: 2371275
PubMed ID: 2211615
Title: cDNA sequence of the human integrin beta 5 subunit.
PubMed ID: 2211615
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 15156152
Title: Myosin-X provides a motor-based link between integrins and the cytoskeleton.
PubMed ID: 15156152
DOI: 10.1038/ncb1136
PubMed ID: 15611078
Title: Integrin-dependent functions of the angiogenic inducer NOV (CCN3): implication in wound healing.
PubMed ID: 15611078
PubMed ID: 20615244
Title: Integrin alphavbeta5 is a primary receptor for adenovirus in CAR-negative cells.
PubMed ID: 20615244
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 35687021
Title: PEAK1 Y635 phosphorylation regulates cell migration through association with Tensin3 and integrins.
PubMed ID: 35687021
Sequence Information:
- Length: 799
- Mass: 88054
- Checksum: D7E4727CA310512B
- Sequence:
MPRAPAPLYA CLLGLCALLP RLAGLNICTS GSATSCEECL LIHPKCAWCS KEDFGSPRSI TSRCDLRANL VKNGCGGEIE SPASSFHVLR SLPLSSKGSG SAGWDVIQMT PQEIAVNLRP GDKTTFQLQV RQVEDYPVDL YYLMDLSLSM KDDLDNIRSL GTKLAEEMRK LTSNFRLGFG SFVDKDISPF SYTAPRYQTN PCIGYKLFPN CVPSFGFRHL LPLTDRVDSF NEEVRKQRVS RNRDAPEGGF DAVLQAAVCK EKIGWRKDAL HLLVFTTDDV PHIALDGKLG GLVQPHDGQC HLNEANEYTA SNQMDYPSLA LLGEKLAENN INLIFAVTKN HYMLYKNFTA LIPGTTVEIL DGDSKNIIQL IINAYNSIRS KVELSVWDQP EDLNLFFTAT CQDGVSYPGQ RKCEGLKIGD TASFEVSLEA RSCPSRHTEH VFALRPVGFR DSLEVGVTYN CTCGCSVGLE PNSARCNGSG TYVCGLCECS PGYLGTRCEC QDGENQSVYQ NLCREAEGKP LCSGRGDCSC NQCSCFESEF GKIYGPFCEC DNFSCARNKG VLCSGHGECH CGECKCHAGY IGDNCNCSTD ISTCRGRDGQ ICSERGHCLC GQCQCTEPGA FGEMCEKCPT CPDACSTKRD CVECLLLHSG KPDNQTCHSL CRDEVITWVD TIVKDDQEAV LCFYKTAKDC VMMFTYVELP SGKSNLTVLR EPECGNTPNA MTILLAVVGS ILLVGLALLA IWKLLVTIHD RREFAKFQSE RSRARYEMAS NPLYRKPIST HTVDFTFNKF NKSYNGTVD
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.