Details for: ITIH3
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: hepatoblast (CL0005026)
Fold Change: 3.31
Marker Score: 10,848 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 2.93
Marker Score: 15,756 - Cell Name: midzonal region hepatocyte (CL0019028)
Fold Change: 2.04
Marker Score: 8,804 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 1.97
Marker Score: 12,697 - Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
Fold Change: 1.44
Marker Score: 1,541 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 1.38
Marker Score: 874 - Cell Name: inflammatory macrophage (CL0000863)
Fold Change: 1.34
Marker Score: 415 - Cell Name: goblet cell (CL0000160)
Fold Change: 1.14
Marker Score: 7,604 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.01
Marker Score: 2,579 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,833 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48,058 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,409 - Cell Name: tracheobronchial smooth muscle cell (CL0019019)
Fold Change: 0.96
Marker Score: 280 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.94
Marker Score: 5,354 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.92
Marker Score: 2,741 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,296 - Cell Name: hepatocyte (CL0000182)
Fold Change: 0.84
Marker Score: 571 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1,265 - Cell Name: brush cell (CL0002204)
Fold Change: 0.78
Marker Score: 711 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.77
Marker Score: 399 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.77
Marker Score: 589 - Cell Name: muscle cell (CL0000187)
Fold Change: 0.75
Marker Score: 213 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.7
Marker Score: 180 - Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
Fold Change: 0.68
Marker Score: 148 - Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
Fold Change: 0.66
Marker Score: 182 - Cell Name: Kupffer cell (CL0000091)
Fold Change: 0.58
Marker Score: 581 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.57
Marker Score: 456 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.56
Marker Score: 149 - Cell Name: kidney proximal convoluted tubule epithelial cell (CL1000838)
Fold Change: 0.53
Marker Score: 1,107 - Cell Name: renal beta-intercalated cell (CL0002201)
Fold Change: 0.53
Marker Score: 169 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: 0.52
Marker Score: 195 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 0.47
Marker Score: 280 - Cell Name: bronchial smooth muscle cell (CL0002598)
Fold Change: 0.39
Marker Score: 109 - Cell Name: erythroblast (CL0000765)
Fold Change: 0.37
Marker Score: 234 - Cell Name: mast cell (CL0000097)
Fold Change: 0.36
Marker Score: 211 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.34
Marker Score: 649 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 0.3
Marker Score: 305 - Cell Name: supporting cell (CL0000630)
Fold Change: 0.29
Marker Score: 544 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.27
Marker Score: 4,272 - Cell Name: megakaryocyte (CL0000556)
Fold Change: 0.25
Marker Score: 142 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.25
Marker Score: 503 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 0.24
Marker Score: 100 - Cell Name: mesothelial cell (CL0000077)
Fold Change: 0.22
Marker Score: 87 - Cell Name: mature NK T cell (CL0000814)
Fold Change: 0.21
Marker Score: 99 - Cell Name: alpha-beta T cell (CL0000789)
Fold Change: 0.21
Marker Score: 158 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.2
Marker Score: 94 - Cell Name: myometrial cell (CL0002366)
Fold Change: 0.2
Marker Score: 56 - Cell Name: smooth muscle cell (CL0000192)
Fold Change: 0.19
Marker Score: 127 - Cell Name: blood vessel smooth muscle cell (CL0019018)
Fold Change: 0.19
Marker Score: 50 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 0.19
Marker Score: 70 - Cell Name: plasmacytoid dendritic cell (CL0000784)
Fold Change: 0.18
Marker Score: 97 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.16
Marker Score: 98 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.14
Marker Score: 335 - Cell Name: M cell of gut (CL0000682)
Fold Change: 0.14
Marker Score: 36 - Cell Name: contractile cell (CL0000183)
Fold Change: 0.14
Marker Score: 75 - Cell Name: gamma-delta T cell (CL0000798)
Fold Change: 0.12
Marker Score: 84 - Cell Name: Leydig cell (CL0000178)
Fold Change: 0.12
Marker Score: 132 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.12
Marker Score: 39 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.12
Marker Score: 80 - Cell Name: vascular associated smooth muscle cell (CL0000359)
Fold Change: 0.12
Marker Score: 55 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 0.12
Marker Score: 111 - Cell Name: innate lymphoid cell (CL0001065)
Fold Change: 0.11
Marker Score: 41 - Cell Name: endothelial cell of lymphatic vessel (CL0002138)
Fold Change: 0.11
Marker Score: 71 - Cell Name: kidney interstitial cell (CL1000500)
Fold Change: 0.11
Marker Score: 76 - Cell Name: amacrine cell (CL0000561)
Fold Change: 0.09
Marker Score: 292 - Cell Name: interstitial cell of Cajal (CL0002088)
Fold Change: 0.09
Marker Score: 30 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 0.09
Marker Score: 22 - Cell Name: enterocyte of colon (CL1000347)
Fold Change: 0.09
Marker Score: 132 - Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
Fold Change: 0.08
Marker Score: 86 - Cell Name: hematopoietic stem cell (CL0000037)
Fold Change: 0.08
Marker Score: 44 - Cell Name: mesothelial cell of epicardium (CL0011019)
Fold Change: 0.08
Marker Score: 26 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 0.08
Marker Score: 21 - Cell Name: parietal epithelial cell (CL1000452)
Fold Change: 0.08
Marker Score: 29 - Cell Name: fibroblast (CL0000057)
Fold Change: 0.08
Marker Score: 76 - Cell Name: progenitor cell of endocrine pancreas (CL0002351)
Fold Change: 0.08
Marker Score: 17 - Cell Name: plasma cell (CL0000786)
Fold Change: 0.07
Marker Score: 81 - Cell Name: neuronal receptor cell (CL0000006)
Fold Change: 0.07
Marker Score: 32 - Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 0.07
Marker Score: 170 - Cell Name: erythrocyte (CL0000232)
Fold Change: 0.07
Marker Score: 40 - Cell Name: pericyte (CL0000669)
Fold Change: 0.07
Marker Score: 42 - Cell Name: late promyelocyte (CL0002151)
Fold Change: 0.07
Marker Score: 17 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.06
Marker Score: 20 - Cell Name: Unknown (CL0000003)
Fold Change: 0.06
Marker Score: 196 - Cell Name: type L enteroendocrine cell (CL0002279)
Fold Change: 0.06
Marker Score: 17 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 0.06
Marker Score: 17 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 0.06
Marker Score: 104 - Cell Name: mesangial cell (CL0000650)
Fold Change: 0.06
Marker Score: 72 - Cell Name: podocyte (CL0000653)
Fold Change: 0.06
Marker Score: 22 - Cell Name: conventional dendritic cell (CL0000990)
Fold Change: 0.06
Marker Score: 41 - Cell Name: epithelial cell of glomerular capsule (CL1000450)
Fold Change: 0.06
Marker Score: 15 - Cell Name: endothelial cell (CL0000115)
Fold Change: 0.06
Marker Score: 52 - Cell Name: retinal pigment epithelial cell (CL0002586)
Fold Change: 0.06
Marker Score: 17 - Cell Name: theca cell (CL0000503)
Fold Change: 0.06
Marker Score: 41 - Cell Name: microglial cell (CL0000129)
Fold Change: 0.06
Marker Score: 104 - Cell Name: myeloid cell (CL0000763)
Fold Change: 0.06
Marker Score: 91 - Cell Name: erythroid lineage cell (CL0000764)
Fold Change: 0.06
Marker Score: 28 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.06
Marker Score: 94 - Cell Name: type D enteroendocrine cell (CL0000502)
Fold Change: 0.06
Marker Score: 17 - Cell Name: B cell (CL0000236)
Fold Change: 0.05
Marker Score: 52 - Cell Name: renal principal cell (CL0005009)
Fold Change: 0.05
Marker Score: 42
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3761771970
Symbol: ITIH3_HUMAN
Name: Inter-alpha-trypsin inhibitor heavy chain H3
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7681778
Title: Human pre-alpha-trypsin inhibitor-precursor heavy chain. cDNA and deduced amino-acid sequence.
PubMed ID: 7681778
PubMed ID: 9756925
Title: Human inter-alpha-trypsin inhibitor heavy chain H3 gene. Genomic organization, promoter analysis, and gene linkage.
PubMed ID: 9756925
PubMed ID: 16641997
Title: The DNA sequence, annotation and analysis of human chromosome 3.
PubMed ID: 16641997
DOI: 10.1038/nature04728
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 7522574
Title: Tandem orientation of the inter-alpha-trypsin inhibitor heavy chain H1 and H3 genes.
PubMed ID: 7522574
PubMed ID: 2476436
Title: Analysis of inter-alpha-trypsin inhibitor and a novel trypsin inhibitor, pre-alpha-trypsin inhibitor, from human plasma. Polypeptide chain stoichiometry and assembly by glycan.
PubMed ID: 2476436
PubMed ID: 2465147
Title: Human plasma inter-alpha-trypsin inhibitor is encoded by four genes on three chromosomes.
PubMed ID: 2465147
PubMed ID: 1898736
Title: Chondroitin 4-sulfate covalently cross-links the chains of the human blood protein pre-alpha-inhibitor.
PubMed ID: 1898736
PubMed ID: 16335952
Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.
PubMed ID: 16335952
DOI: 10.1021/pr0502065
Sequence Information:
- Length: 890
- Mass: 99849
- Checksum: 03B2B768784CB440
- Sequence:
MAFAWWPCLI LALLSSLAAS GFPRSPFRLL GKRSLPEGVA NGIEVYSTKI NSKVTSRFAH NVVTMRAVNR ADTAKEVSFD VELPKTAFIT NFTLTIDGVT YPGNVKEKEV AKKQYEKAVS QGKTAGLVKA SGRKLEKFTV SVNVAAGSKV TFELTYEELL KRHKGKYEMY LKVQPKQLVK HFEIEVDIFE PQGISMLDAE ASFITNDLLG SALTKSFSGK KGHVSFKPSL DQQRSCPTCT DSLLNGDFTI TYDVNRESPG NVQIVNGYFV HFFAPQGLPV VPKNVAFVID ISGSMAGRKL EQTKEALLRI LEDMQEEDYL NFILFSGDVS TWKEHLVQAT PENLQEARTF VKSMEDKGMT NINDGLLRGI SMLNKAREEH RIPERSTSIV IMLTDGDANV GESRPEKIQE NVRNAIGGKF PLYNLGFGNN LNYNFLENMA LENHGFARRI YEDSDADLQL QGFYEEVANP LLTGVEMEYP ENAILDLTQN TYQHFYDGSE IVVAGRLVDE DMNSFKADVK GHGATNDLTF TEEVDMKEME KALQERDYIF GNYIERLWAY LTIEQLLEKR KNAHGEEKEN LTARALDLSL KYHFVTPLTS MVVTKPEDNE DERAIADKPG EDAEATPVSP AMSYLTSYQP PQNPYYYVDG DPHFIIQIPE KDDALCFNID EAPGTVLRLI QDAVTGLTVN GQITGDKRGS PDSKTRKTYF GKLGIANAQM DFQVEVTTEK ITLWNRAVPS TFSWLDTVTV TQDGLSMMIN RKNMVVSFGD GVTFVVVLHQ VWKKHPVHRD FLGFYVVDSH RMSAQTHGLL GQFFQPFDFK VSDIRPGSDP TKPDATLVVK NHQLIVTRGS QKDYRKDASI GTKVVCWFVH NNGEGLIDGV HTDYIVPNLF
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.