Details for: KCNB1

Gene ID: 3745

Symbol: KCNB1

Ensembl ID: ENSG00000158445

Description: potassium voltage-gated channel subfamily B member 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 93.4383
    Cell Significance Index: -23.7000
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 9.9332
    Cell Significance Index: 118.4100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 9.8466
    Cell Significance Index: 620.6000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 6.0161
    Cell Significance Index: -23.7400
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 4.0719
    Cell Significance Index: 89.1600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 3.3928
    Cell Significance Index: 150.0700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 3.1219
    Cell Significance Index: 118.2200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.6509
    Cell Significance Index: 531.7600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 2.5103
    Cell Significance Index: 153.9100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 2.3416
    Cell Significance Index: 157.4500
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 2.2136
    Cell Significance Index: 63.1700
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: 2.2085
    Cell Significance Index: 27.8100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.1282
    Cell Significance Index: 763.3600
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: 1.6039
    Cell Significance Index: 20.8000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.9610
    Cell Significance Index: 59.0700
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.7689
    Cell Significance Index: 18.4400
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 0.7419
    Cell Significance Index: 5.6900
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.6555
    Cell Significance Index: 16.8500
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 0.4635
    Cell Significance Index: 4.4100
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: 0.4158
    Cell Significance Index: 5.0400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3545
    Cell Significance Index: 320.0500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.3067
    Cell Significance Index: 30.3400
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 0.1741
    Cell Significance Index: 2.4500
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.1601
    Cell Significance Index: 26.0400
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.1356
    Cell Significance Index: 14.7500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.1355
    Cell Significance Index: 61.4800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.1128
    Cell Significance Index: 5.9300
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: 0.1103
    Cell Significance Index: 0.4800
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: 0.0971
    Cell Significance Index: 1.2100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0559
    Cell Significance Index: 11.0900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0443
    Cell Significance Index: 0.7600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0404
    Cell Significance Index: 1.8300
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.0310
    Cell Significance Index: 1.8600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0092
    Cell Significance Index: 17.3300
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.0030
    Cell Significance Index: -0.0200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0037
    Cell Significance Index: -6.8000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0080
    Cell Significance Index: -12.2800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0083
    Cell Significance Index: -11.2800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0157
    Cell Significance Index: -2.8300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0185
    Cell Significance Index: -0.6500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0198
    Cell Significance Index: -0.5700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0244
    Cell Significance Index: -18.0800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0250
    Cell Significance Index: -15.9000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0286
    Cell Significance Index: -20.9500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0302
    Cell Significance Index: -16.5200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0307
    Cell Significance Index: -23.2700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.0325
    Cell Significance Index: -2.2500
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0353
    Cell Significance Index: -0.5100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0358
    Cell Significance Index: -20.1900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0387
    Cell Significance Index: -24.1600
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0407
    Cell Significance Index: -0.8500
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0423
    Cell Significance Index: -0.8500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0438
    Cell Significance Index: -1.1000
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0481
    Cell Significance Index: -1.0200
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0554
    Cell Significance Index: -24.4800
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0657
    Cell Significance Index: -1.3000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0678
    Cell Significance Index: -2.2200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0688
    Cell Significance Index: -19.8100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.1043
    Cell Significance Index: -2.2600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1047
    Cell Significance Index: -22.0600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1205
    Cell Significance Index: -17.5200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.1253
    Cell Significance Index: -21.4000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.1265
    Cell Significance Index: -15.5500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.1430
    Cell Significance Index: -19.6400
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1542
    Cell Significance Index: -4.9100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1603
    Cell Significance Index: -18.6900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.1611
    Cell Significance Index: -20.6500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1620
    Cell Significance Index: -20.9300
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.1680
    Cell Significance Index: -3.6300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1928
    Cell Significance Index: -22.0900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1952
    Cell Significance Index: -23.0200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1989
    Cell Significance Index: -6.3700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.2032
    Cell Significance Index: -20.7600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2164
    Cell Significance Index: -22.5300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2408
    Cell Significance Index: -13.5100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.2449
    Cell Significance Index: -11.4200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.2643
    Cell Significance Index: -20.2800
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: -0.2676
    Cell Significance Index: -3.7000
  • Cell Name: OFF-bipolar cell (CL0000750)
    Fold Change: -0.2736
    Cell Significance Index: -2.4100
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.2874
    Cell Significance Index: -7.1700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2877
    Cell Significance Index: -21.4400
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.2980
    Cell Significance Index: -4.4900
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.3093
    Cell Significance Index: -3.3700
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.3191
    Cell Significance Index: -6.6600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.3221
    Cell Significance Index: -16.7300
  • Cell Name: chandelier cell (CL4023083)
    Fold Change: -0.3282
    Cell Significance Index: -2.6500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.3322
    Cell Significance Index: -21.4300
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.3403
    Cell Significance Index: -11.9200
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.3454
    Cell Significance Index: -15.0200
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.3497
    Cell Significance Index: -5.0300
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.3633
    Cell Significance Index: -11.4900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.3660
    Cell Significance Index: -17.2000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.3680
    Cell Significance Index: -19.1700
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.3699
    Cell Significance Index: -26.1600
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.3789
    Cell Significance Index: -8.0700
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.4201
    Cell Significance Index: -5.2100
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.4258
    Cell Significance Index: -10.3900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.4269
    Cell Significance Index: -11.9300
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: -0.4275
    Cell Significance Index: -4.8300
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.4532
    Cell Significance Index: -5.4200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Subunit composition:** KCNB1 forms heteromeric channels with other subunits, such as KCNE1, KCNE2, KCNE3, and KCNE4, which contribute to the channel's biophysical properties. 2. **Biophysical properties:** KCNB1 channels exhibit delayed rectifier potassium current, which is essential for regulating the resting membrane potential and action potentials in neurons. 3. **Expression patterns:** KCNB1 is widely expressed in the nervous system, including neurons, glial cells, and photoreceptor cells, as well as in thymocytes and other immune cells. 4. **Regulatory mechanisms:** KCNB1 channels are subject to regulatory mechanisms, including phosphorylation, palmitoylation, and interactions with other proteins, which modulate their biophysical properties and activity. **Pathways and Functions:** 1. **Regulation of action potentials:** KCNB1 channels contribute to the regulation of action potentials in neurons, particularly in the central nervous system. 2. **Insulin secretion:** KCNB1 channels are involved in the regulation of insulin secretion in pancreatic beta cells. 3. **Calcium-dependent exocytosis:** KCNB1 channels play a critical role in regulating calcium-dependent exocytosis in neurons and other cells. 4. **Neurotransmitter release:** KCNB1 channels are involved in the regulation of neurotransmitter release in the central nervous system. 5. **Metabolic regulation:** KCNB1 channels contribute to the regulation of glucose and energy metabolism in the body. **Clinical Significance:** 1. **Neurological disorders:** Alterations in KCNB1 expression or function have been implicated in various neurological disorders, including epilepsy, Parkinson's disease, and Alzheimer's disease. 2. **Metabolic disorders:** KCNB1 channels contribute to the regulation of insulin secretion and glucose metabolism, making them a potential target for the treatment of metabolic disorders, such as type 2 diabetes. 3. **Cancer:** KCNB1 channels are involved in the regulation of cell growth and survival, making them a potential target for cancer therapy. 4. **Therapeutic applications:** KCNB1 channels have been targeted for the treatment of various diseases, including epilepsy, Parkinson's disease, and metabolic disorders. In conclusion, the KCNB1 gene plays a critical role in the regulation of cellular processes, including action potentials, insulin secretion, and calcium-dependent exocytosis. Alterations in KCNB1 expression or function have been implicated in various diseases, making it a potential target for therapeutic interventions. Further research is needed to fully understand the mechanisms of KCNB1 channels and their role in human disease.

Genular Protein ID: 3476246891

Symbol: KCNB1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q14721 Q14193

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CORUM 1 CTD 1 ChEBI 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 4 DrugCentral 1 EMBL 4 Ensembl 2 ExpressionAtlas 1 GO 43 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OGP 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PIR 1 PRINTS 4 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 2 RefSeq 3 Rhea 1 SASBDB 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 8081723

Title: Cloning and characterization of a human delayed rectifier potassium channel gene.

PubMed ID: 8081723

PubMed ID: 1283219

Title: Heterologous expression of the human potassium channel Kv2.1 in clonal mammalian cells by direct cytoplasmic microinjection of cRNA.

PubMed ID: 1283219

DOI: 10.1007/bf00370422

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 10484328

Title: Electrically silent potassium channel subunits from human lens epithelium.

PubMed ID: 10484328

DOI: 10.1152/ajpcell.1999.277.3.c412

PubMed ID: 10414301

Title: Molecular diversity of K+ channels.

PubMed ID: 10414301

DOI: 10.1111/j.1749-6632.1999.tb11293.x

PubMed ID: 11852086

Title: Molecular cloning and characterization of Kv6.3, a novel modulatory subunit for voltage-gated K(+) channel Kv2.1.

PubMed ID: 11852086

DOI: 10.1016/s0014-5793(02)02267-6

PubMed ID: 12403834

Title: Synaptosome-associated protein of 25 kilodaltons modulates Kv2.1 voltage-dependent K(+) channels in neuroendocrine islet beta-cells through an interaction with the channel N terminus.

PubMed ID: 12403834

DOI: 10.1210/me.2002-0058

PubMed ID: 12060745

Title: Obligatory heterotetramerization of three previously uncharacterized Kv channel alpha-subunits identified in the human genome.

PubMed ID: 12060745

DOI: 10.1073/pnas.122617999

PubMed ID: 14565763

Title: Structural basis of binding and inhibition of novel tarantula toxins in mammalian voltage-dependent potassium channels.

PubMed ID: 14565763

DOI: 10.1021/tx0341097

PubMed ID: 12560340

Title: The Roles of N- and C-terminal determinants in the activation of the Kv2.1 potassium channel.

PubMed ID: 12560340

DOI: 10.1074/jbc.m212973200

PubMed ID: 14988243

Title: Expression of voltage-gated potassium channels in human and rhesus pancreatic islets.

PubMed ID: 14988243

DOI: 10.2337/diabetes.53.3.597

PubMed ID: 15858231

Title: Molecular determinants of voltage-gated potassium currents in vascular smooth muscle.

PubMed ID: 15858231

DOI: 10.1385/cbb:42:2:167

PubMed ID: 19357235

Title: Kv2.1 and silent Kv subunits underlie the delayed rectifier K+ current in cultured small mouse DRG neurons.

PubMed ID: 19357235

DOI: 10.1152/ajpcell.00088.2009

PubMed ID: 19074135

Title: Mutation of histidine 105 in the T1 domain of the potassium channel Kv2.1 disrupts heteromerization with Kv6.3 and Kv6.4.

PubMed ID: 19074135

DOI: 10.1074/jbc.m808786200

PubMed ID: 19717558

Title: Conserved negative charges in the N-terminal tetramerization domain mediate efficient assembly of Kv2.1 and Kv2.1/Kv6.4 channels.

PubMed ID: 19717558

DOI: 10.1074/jbc.m109.039479

PubMed ID: 19223394

Title: SUMOylation regulates Kv2.1 and modulates pancreatic beta-cell excitability.

PubMed ID: 19223394

DOI: 10.1242/jcs.036632

PubMed ID: 23161216

Title: The role of voltage-gated potassium channels Kv2.1 and Kv2.2 in the regulation of insulin and somatostatin release from pancreatic islets.

PubMed ID: 23161216

DOI: 10.1124/jpet.112.199083

PubMed ID: 24477962

Title: A unique ion channel clustering domain on the axon initial segment of mammalian neurons.

PubMed ID: 24477962

DOI: 10.1002/cne.23551

PubMed ID: 24901643

Title: The subfamily-specific interaction between Kv2.1 and Kv6.4 subunits is determined by interactions between the N- and C-termini.

PubMed ID: 24901643

DOI: 10.1371/journal.pone.0098960

PubMed ID: 34535971

Title: Compound heterozygous KCNV2 variants contribute to cone dystrophy with supernormal rod responses in a Chinese family.

PubMed ID: 34535971

DOI: 10.1002/mgg3.1795

PubMed ID: 33124732

Title: FFAT motif phosphorylation controls formation and lipid transfer function of inter-organelle contacts.

PubMed ID: 33124732

DOI: 10.15252/embj.2019104369

PubMed ID: 25164438

Title: De novo KCNB1 mutations in epileptic encephalopathy.

PubMed ID: 25164438

DOI: 10.1002/ana.24263

PubMed ID: 26503721

Title: A novel epileptic encephalopathy mutation in KCNB1 disrupts Kv2.1 ion selectivity, expression, and localization.

PubMed ID: 26503721

DOI: 10.1085/jgp.201511444

PubMed ID: 26477325

Title: De novo KCNB1 mutations in infantile epilepsy inhibit repetitive neuronal firing.

PubMed ID: 26477325

DOI: 10.1038/srep15199

Sequence Information:

  • Length: 858
  • Mass: 95878
  • Checksum: C4B426174ED0DEE4
  • Sequence:
    • MPAGMTKHGS RSTSSLPPEP MEIVRSKACS RRVRLNVGGL AHEVLWRTLD RLPRTRLGKL 
RDCNTHDSLL EVCDDYSLDD NEYFFDRHPG AFTSILNFYR TGRLHMMEEM CALSFSQELD 
YWGIDEIYLE SCCQARYHQK KEQMNEELKR EAETLREREG EEFDNTCCAE KRKKLWDLLE 
KPNSSVAAKI LAIISIMFIV LSTIALSLNT LPELQSLDEF GQSTDNPQLA HVEAVCIAWF 
TMEYLLRFLS SPKKWKFFKG PLNAIDLLAI LPYYVTIFLT ESNKSVLQFQ NVRRVVQIFR 
IMRILRILKL ARHSTGLQSL GFTLRRSYNE LGLLILFLAM GIMIFSSLVF FAEKDEDDTK 
FKSIPASFWW ATITMTTVGY GDIYPKTLLG KIVGGLCCIA GVLVIALPIP IIVNNFSEFY 
KEQKRQEKAI KRREALERAK RNGSIVSMNM KDAFARSIEM MDIVVEKNGE NMGKKDKVQD 
NHLSPNKWKW TKRTLSETSS SKSFETKEQG SPEKARSSSS PQHLNVQQLE DMYNKMAKTQ 
SQPILNTKES AAQSKPKEEL EMESIPSPVA PLPTRTEGVI DMRSMSSIDS FISCATDFPE 
ATRFSHSPLT SLPSKTGGST APEVGWRGAL GASGGRFVEA NPSPDASQHS SFFIESPKSS 
MKTNNPLKLR ALKVNFMEGD PSPLLPVLGM YHDPLRNRGS AAAAVAGLEC ATLLDKAVLS 
PESSIYTTAS AKTPPRSPEK HTAIAFNFEA GVHQYIDADT DDEGQLLYSV DSSPPKSLPG 
STSPKFSTGT RSEKNHFESS PLPTSPKFLR QNCIYSTEAL TGKGPSGQEK CKLENHISPD 
VRVLPGGGAH GSTRDQSI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.