Details for: ARSB

Gene ID: 411

Symbol: ARSB

Ensembl ID: ENSG00000113273

Description: arylsulfatase B

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 151.6601
    Cell Significance Index: -23.5900
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 93.6354
    Cell Significance Index: -23.7500
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 51.6603
    Cell Significance Index: -24.3900
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 21.5660
    Cell Significance Index: -20.5900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 19.5546
    Cell Significance Index: -24.1100
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 8.9814
    Cell Significance Index: -24.0600
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 6.1378
    Cell Significance Index: -24.2200
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 5.9536
    Cell Significance Index: -13.0300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.9705
    Cell Significance Index: 391.0500
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.5661
    Cell Significance Index: 33.4800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.2841
    Cell Significance Index: 257.5900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.1144
    Cell Significance Index: 399.7300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.9563
    Cell Significance Index: 53.6600
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.8239
    Cell Significance Index: 18.0400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.8195
    Cell Significance Index: 81.0700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.8048
    Cell Significance Index: 35.6000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.7752
    Cell Significance Index: 536.1900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.7707
    Cell Significance Index: 29.1900
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.7147
    Cell Significance Index: 645.3200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.6433
    Cell Significance Index: 16.0800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.5271
    Cell Significance Index: 35.4400
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.4906
    Cell Significance Index: 14.0000
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 0.4840
    Cell Significance Index: 7.9700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.4224
    Cell Significance Index: 68.7000
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.3594
    Cell Significance Index: 39.0900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.3094
    Cell Significance Index: 19.0200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.2885
    Cell Significance Index: 6.1500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.2879
    Cell Significance Index: 22.0900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.2193
    Cell Significance Index: 99.5200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1440
    Cell Significance Index: 271.1800
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.1349
    Cell Significance Index: 8.1000
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 0.1239
    Cell Significance Index: 1.0100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1101
    Cell Significance Index: 20.9500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0846
    Cell Significance Index: 1.4500
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.0709
    Cell Significance Index: 1.7000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0462
    Cell Significance Index: 29.3400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0381
    Cell Significance Index: 58.6500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0275
    Cell Significance Index: 50.7400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0199
    Cell Significance Index: 3.5900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0191
    Cell Significance Index: 0.5500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0166
    Cell Significance Index: 22.6200
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 0.0032
    Cell Significance Index: 0.0400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0033
    Cell Significance Index: -0.4800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0078
    Cell Significance Index: -4.2700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0201
    Cell Significance Index: -3.4400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0288
    Cell Significance Index: -21.3200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0297
    Cell Significance Index: -21.7700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0314
    Cell Significance Index: -23.8000
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0346
    Cell Significance Index: -15.3000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0426
    Cell Significance Index: -24.0500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0434
    Cell Significance Index: -27.0900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0504
    Cell Significance Index: -6.2000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0520
    Cell Significance Index: -7.1400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0657
    Cell Significance Index: -4.0300
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0688
    Cell Significance Index: -8.1100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0718
    Cell Significance Index: -20.6700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0743
    Cell Significance Index: -3.3700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0843
    Cell Significance Index: -9.8200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0856
    Cell Significance Index: -10.9700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0973
    Cell Significance Index: -3.4200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0990
    Cell Significance Index: -10.1200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1095
    Cell Significance Index: -11.4000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1283
    Cell Significance Index: -27.0200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1705
    Cell Significance Index: -22.0300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1795
    Cell Significance Index: -20.5700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.2005
    Cell Significance Index: -9.3500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.2027
    Cell Significance Index: -12.7800
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.2084
    Cell Significance Index: -2.9900
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.2189
    Cell Significance Index: -4.5400
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.2351
    Cell Significance Index: -4.7200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.2475
    Cell Significance Index: -12.8900
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.2535
    Cell Significance Index: -4.2700
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.2719
    Cell Significance Index: -17.5400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.2742
    Cell Significance Index: -5.9400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.2748
    Cell Significance Index: -7.6800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2794
    Cell Significance Index: -8.9500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2809
    Cell Significance Index: -22.2500
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.2818
    Cell Significance Index: -5.9800
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: -0.2891
    Cell Significance Index: -2.2100
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.2975
    Cell Significance Index: -21.0400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2976
    Cell Significance Index: -22.1800
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.3078
    Cell Significance Index: -15.9900
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.3259
    Cell Significance Index: -10.3800
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.3479
    Cell Significance Index: -6.4300
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.3485
    Cell Significance Index: -7.5300
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.3500
    Cell Significance Index: -6.9200
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.3543
    Cell Significance Index: -5.9300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.3677
    Cell Significance Index: -17.2800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.3751
    Cell Significance Index: -12.2800
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.3752
    Cell Significance Index: -5.5400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.4078
    Cell Significance Index: -21.4100
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.4277
    Cell Significance Index: -10.6700
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.4648
    Cell Significance Index: -20.2100
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.4648
    Cell Significance Index: -12.4100
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.4651
    Cell Significance Index: -6.8700
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.4744
    Cell Significance Index: -16.6200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.4949
    Cell Significance Index: -12.7200
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.5133
    Cell Significance Index: -8.8800
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: -0.5328
    Cell Significance Index: -6.9100
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.5462
    Cell Significance Index: -18.9800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** ARSB is a sulfatase enzyme that specifically hydrolyzes sulfated GAGs, such as chondroitin-6-sulfate and dermatan sulfate, into their desulfated forms. The enzyme is primarily localized to lysosomes, where it plays a critical role in maintaining the balance of GAGs within the cell. ARSB is also found in azurophil granules, which are specialized storage organelles in neutrophils that contain antimicrobial peptides and enzymes. **Pathways and Functions** ARSB is involved in various cellular processes, including: 1. **Glycosaminoglycan metabolism**: ARSB is essential for the degradation of sulfated GAGs, which are involved in cell signaling, cell migration, and immune response. 2. **Autophagy**: ARSB is involved in the regulation of autophagy, a process by which cells recycle damaged or dysfunctional components, including GAGs. 3. **Neurodevelopment**: ARSB is required for the proper development of neurons, particularly those involved in the regulation of movement and behavior. 4. **Immune system**: ARSB is involved in the regulation of immune responses, particularly in the context of neutrophil activation and degranulation. **Clinical Significance** Mutations in the ARSB gene have been associated with several clinical conditions, including: 1. **Mucopolysaccharidoses**: A group of rare genetic disorders characterized by the accumulation of GAGs in cells and tissues, leading to progressive damage to various organs. 2. **MPS VI**: A subtype of MPS characterized by the accumulation of dermatan sulfate and chondroitin-6-sulfate in cells and tissues, leading to progressive damage to the brain, heart, and lungs. 3. **Neurological disorders**: Mutations in the ARSB gene have been associated with neurological disorders, including intellectual disability, seizures, and movement disorders. In summary, ARSB is a crucial enzyme involved in the degradation of GAGs, and its dysfunction has been associated with several clinical conditions characterized by the accumulation of GAGs in cells and tissues. Further research is needed to elucidate the mechanisms underlying the pathogenesis of these disorders and to develop effective therapeutic strategies for their treatment.

Genular Protein ID: 1737859220

Symbol: ARSB_HUMAN

Name: Arylsulfatase B

UniProtKB Accession Codes:

P15848 B2RC20 Q8N322 Q9UDI9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 2 Bgee 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChEBI 6 ChEMBL 1 ChiTaRS 1 DNASU 1 DisGeNET 1 DisProt 1 DrugBank 1 EC 2 EMBL 18 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 21 Gene3D 2 GeneCards 1 GeneTree 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 5 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 5 RefSeq 3 SABIO-RK 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2303452

Title: Phylogenetic conservation of arylsulfatases. cDNA cloning and expression of human arylsulfatase B.

PubMed ID: 2303452

DOI: 10.1016/s0021-9258(19)39778-9

PubMed ID: 1968043

Title: Human arylsulfatase B: MOPAC cloning, nucleotide sequence of a full-length cDNA, and regions of amino acid identity with arylsulfatases A and C.

PubMed ID: 1968043

DOI: 10.1016/0888-7543(90)90460-c

PubMed ID: 7687847

Title: Structure of the human arylsulfatase B gene.

PubMed ID: 7687847

DOI: 10.1515/bchm3.1993.374.1-6.327

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1930244

Title: Human N-acetylgalactosamine-4-sulphatase: protein maturation and isolation of genomic clones.

PubMed ID: 1930244

PubMed ID: 1390929

Title: Components and proteolytic processing sites of arylsulfatase B from human placenta.

PubMed ID: 1390929

DOI: 10.1016/0167-4838(92)90051-e

PubMed ID: 7628016

Title: A novel amino acid modification in sulfatases that is defective in multiple sulfatase deficiency.

PubMed ID: 7628016

DOI: 10.1016/0092-8674(95)90314-3

PubMed ID: 15146462

Title: Molecular and functional analysis of SUMF1 mutations in multiple sulfatase deficiency.

PubMed ID: 15146462

DOI: 10.1002/humu.20040

PubMed ID: 19306108

Title: Arylsulfatase B regulates colonic epithelial cell migration by effects on MMP9 expression and RhoA activation.

PubMed ID: 19306108

DOI: 10.1007/s10585-009-9253-z

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 9032078

Title: Structure of a human lysosomal sulfatase.

PubMed ID: 9032078

DOI: 10.1016/s0969-2126(97)00185-8

PubMed ID: 1718978

Title: Mucopolysaccharidosis VI (Maroteaux-Lamy syndrome). An intermediate clinical phenotype caused by substitution of valine for glycine at position 137 of arylsulfatase B.

PubMed ID: 1718978

DOI: 10.1016/s0021-9258(18)54649-4

PubMed ID: 1550123

Title: Mucopolysaccharidosis type VI: identification of three mutations in the arylsulfatase B gene of patients with the severe and mild phenotypes provides molecular evidence for genetic heterogeneity.

PubMed ID: 1550123

PubMed ID: 8116615

Title: Mucopolysaccharidosis VI (Maroteaux-Lamy syndrome): six unique arylsulfatase B gene alleles causing variable disease phenotypes.

PubMed ID: 8116615

PubMed ID: 8125475

Title: Four novel mutant alleles of the arylsulfatase B gene in two patients with intermediate form of mucopolysaccharidosis VI (Maroteaux-Lamy syndrome).

PubMed ID: 8125475

DOI: 10.1007/bf00212019

PubMed ID: 8541342

Title: N-acetylgalactosamine-4-sulfatase: identification of four new mutations within the conserved sulfatase region causing mucopolysaccharidosis type VI.

PubMed ID: 8541342

DOI: 10.1016/0925-4439(95)00070-4

PubMed ID: 8651289

Title: Identification, expression, and biochemical characterization of N-acetylgalactosamine-4-sulfatase mutations and relationship with clinical phenotype in MPS6 patients.

PubMed ID: 8651289

PubMed ID: 10206678

Title: Two novel mutations of the arylsulfatase B gene in two Italian patients with severe form of mucopolysaccharidosis.

PubMed ID: 10206678

DOI: 10.1002/(sici)1098-1004(1998)11:5<410::aid-humu9>3.0.co;2-q

PubMed ID: 9582121

Title: Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome.

PubMed ID: 9582121

DOI: 10.1126/science.280.5366.1077

PubMed ID: 10036316

Title: Maroteaux-Lamy syndrome: five novel mutations and their structural localization.

PubMed ID: 10036316

DOI: 10.1016/s0925-4439(98)00099-4

PubMed ID: 10738004

Title: A novel mutation (Q239R) identified in a Taiwan Chinese patient with type VI mucopolysaccharidosis (Maroteaux-Lamy syndrome).

PubMed ID: 10738004

DOI: 10.1002/(sici)1098-1004(200004)15:4<389::aid-humu31>3.0.co;2-0

PubMed ID: 11802522

Title: Mucopolysaccharidosis type VI: report of two Taiwanese patients and identification of one novel mutation.

PubMed ID: 11802522

PubMed ID: 14974081

Title: Mutational analysis of mucopolysaccharidosis type VI patients undergoing a trial of enzyme replacement therapy.

PubMed ID: 14974081

DOI: 10.1002/humu.10313

PubMed ID: 19259130

Title: Segregation analysis in a family at risk for the Maroteaux-Lamy syndrome conclusively reveals c.1151G>A (p.S384N) as to be a polymorphism.

PubMed ID: 19259130

DOI: 10.1038/ejhg.2009.19

Sequence Information:

  • Length: 533
  • Mass: 59687
  • Checksum: 5983FB6911C4789A
  • Sequence:
    • MGPRGAASLP RGPGPRRLLL PVVLPLLLLL LLAPPGSGAG ASRPPHLVFL LADDLGWNDV 
GFHGSRIRTP HLDALAAGGV LLDNYYTQPL CTPSRSQLLT GRYQIRTGLQ HQIIWPCQPS 
CVPLDEKLLP QLLKEAGYTT HMVGKWHLGM YRKECLPTRR GFDTYFGYLL GSEDYYSHER 
CTLIDALNVT RCALDFRDGE EVATGYKNMY STNIFTKRAI ALITNHPPEK PLFLYLALQS 
VHEPLQVPEE YLKPYDFIQD KNRHHYAGMV SLMDEAVGNV TAALKSSGLW NNTVFIFSTD 
NGGQTLAGGN NWPLRGRKWS LWEGGVRGVG FVASPLLKQK GVKNRELIHI SDWLPTLVKL 
ARGHTNGTKP LDGFDVWKTI SEGSPSPRIE LLHNIDPNFV DSSPCPRNSM APAKDDSSLP 
EYSAFNTSVH AAIRHGNWKL LTGYPGCGYW FPPPSQYNVS EIPSSDPPTK TLWLFDIDRD 
PEERHDLSRE YPHIVTKLLS RLQFYHKHSV PVYFPAQDPR CDPKATGVWG PWM

Genular Protein ID: 3146334092

Symbol: A8K4A0_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K4A0

Database IDs:

ARBA 3 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 1 DNASU 1 DisGeNET 1 EMBL 2 GO 1 Gene3D 2 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 1 SAM 1 SUPFAM 1

Sequence Information:

  • Length: 413
  • Mass: 46028
  • Checksum: D4B6A96052E6FC68
  • Sequence:
    • MGPRGAASLP RGPGPRRLLL PVVLPLLLLL LLAPPGSGAG ASRPPHLVFL LADDLGWNDV 
GFHGSRIRTP HLDALAAGGV LLDNYYTQPL CTPSRSQLLT GRYQIRTGLQ HQIIWPCQPS 
CVPLDEKLLP QLLKEAGYTT HMVGKWHLGM YRKECLPTRR GFDTYFGYLL GSEDYYSHER 
CTLIDALNVT RCALDFRDGE EVATGYKNMY STNIFTKRAI ALITNHPPEK PLFLYLALQS 
VHEPLQVPEE YLKPYDFIQD KNRHHYAGMV SLMDEAVGNV TAALKSSGLW NNTVFIFSTD 
NGGQTLAGGN NWPLRGRKWS LWEGGVRGVG FVASPLLKQK GVKNRELIHI SDWLPTLVKL 
ARGHTNGTKP LDGFDMWKTI SEGSPSPRIE LLHNIDPNFV DSSPYWPECS LLL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.