Details for: MAN2A2
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 100.9353
Cell Significance Index: -15.7000 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 64.2635
Cell Significance Index: -16.3000 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 40.3931
Cell Significance Index: -16.4100 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 37.0831
Cell Significance Index: -19.0800 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 17.1983
Cell Significance Index: -16.4200 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 14.5991
Cell Significance Index: -18.0000 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 7.1635
Cell Significance Index: -19.1900 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 5.2418
Cell Significance Index: -16.1000 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 4.8225
Cell Significance Index: -19.0300 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 2.1612
Cell Significance Index: -4.7300 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 1.2026
Cell Significance Index: 75.8000 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.9609
Cell Significance Index: 867.6500 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.8610
Cell Significance Index: 172.7100 - Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: 0.7330
Cell Significance Index: 5.6500 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.6750
Cell Significance Index: 109.7900 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.6556
Cell Significance Index: 64.8500 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.6136
Cell Significance Index: 66.7500 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.5364
Cell Significance Index: 15.4600 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.5112
Cell Significance Index: 39.2300 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.4765
Cell Significance Index: 21.6000 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.4402
Cell Significance Index: 26.4300 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.3851
Cell Significance Index: 138.1300 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.3750
Cell Significance Index: 259.3700 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.3508
Cell Significance Index: 7.6000 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.2958
Cell Significance Index: 18.1800 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.2911
Cell Significance Index: 20.1300 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.2788
Cell Significance Index: 6.1100 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.2786
Cell Significance Index: 55.2800 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.2541
Cell Significance Index: 11.2400 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.2214
Cell Significance Index: 5.9300 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.2210
Cell Significance Index: 8.3700 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 0.2169
Cell Significance Index: 2.6900 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: 0.2064
Cell Significance Index: 3.1100 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.2027
Cell Significance Index: 9.4500 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.1807
Cell Significance Index: 11.6600 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.1788
Cell Significance Index: 32.2400 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.1688
Cell Significance Index: 4.2200 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.1553
Cell Significance Index: 4.3400 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.0886
Cell Significance Index: 4.6500 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0874
Cell Significance Index: 14.9300 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0865
Cell Significance Index: 3.0400 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.0822
Cell Significance Index: 5.5300 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0798
Cell Significance Index: 10.2300 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0779
Cell Significance Index: 42.5300 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.0706
Cell Significance Index: 13.4400 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.0565
Cell Significance Index: 7.7600 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.0397
Cell Significance Index: 4.8800 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0344
Cell Significance Index: 64.8500 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.0309
Cell Significance Index: 0.7400 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0308
Cell Significance Index: 13.6000 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.0214
Cell Significance Index: 1.2000 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0112
Cell Significance Index: 7.1400 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0097
Cell Significance Index: 14.9800 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0062
Cell Significance Index: 11.5200 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0050
Cell Significance Index: -3.7300 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0066
Cell Significance Index: -4.1200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0069
Cell Significance Index: -9.3400 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0122
Cell Significance Index: -5.5500 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0161
Cell Significance Index: -11.7900 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0173
Cell Significance Index: -13.1300 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.0201
Cell Significance Index: -0.2400 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0205
Cell Significance Index: -2.9800 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0231
Cell Significance Index: -13.0300 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0236
Cell Significance Index: -0.6300 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0459
Cell Significance Index: -9.6700 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0471
Cell Significance Index: -13.5600 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0482
Cell Significance Index: -4.9200 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.0572
Cell Significance Index: -2.9700 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0734
Cell Significance Index: -8.6600 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0777
Cell Significance Index: -9.0500 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.0875
Cell Significance Index: -1.5000 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.0883
Cell Significance Index: -1.8800 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.0887
Cell Significance Index: -6.2700 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0900
Cell Significance Index: -10.3200 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0909
Cell Significance Index: -11.7400 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -0.0985
Cell Significance Index: -1.6600 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.1052
Cell Significance Index: -4.9400 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.1084
Cell Significance Index: -2.9000 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.1144
Cell Significance Index: -5.9600 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.1489
Cell Significance Index: -4.7700 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1489
Cell Significance Index: -15.5000 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.1508
Cell Significance Index: -4.1100 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.1564
Cell Significance Index: -17.8600 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.1763
Cell Significance Index: -13.1400 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.1782
Cell Significance Index: -4.5800 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.2263
Cell Significance Index: -17.9200 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.2271
Cell Significance Index: -6.4800 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -0.2443
Cell Significance Index: -5.9600 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.2514
Cell Significance Index: -3.7100 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -0.2597
Cell Significance Index: -4.8000 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.2655
Cell Significance Index: -3.9200 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.2782
Cell Significance Index: -8.8600 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.3013
Cell Significance Index: -9.8700 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.3034
Cell Significance Index: -6.4400 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.3066
Cell Significance Index: -6.1600 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.3078
Cell Significance Index: -4.2000 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.3135
Cell Significance Index: -19.2200 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.3175
Cell Significance Index: -6.8600 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.3368
Cell Significance Index: -6.6600 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.3488
Cell Significance Index: -8.9100
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 568902954
Symbol: MA2A2_HUMAN
Name: Alpha-mannosidase 2x
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8524845
Title: Molecular cloning and expression of cDNAs encoding human alpha-mannosidase II and a previously unrecognized alpha-mannosidase IIx isozyme.
PubMed ID: 8524845
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16572171
Title: Analysis of the DNA sequence and duplication history of human chromosome 15.
PubMed ID: 16572171
DOI: 10.1038/nature04601
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 14759258
Sequence Information:
- Length: 1150
- Mass: 130539
- Checksum: BFB3D763A6A55444
- Sequence:
MKLKKQVTVC GAAIFCVAVF SLYLMLDRVQ HDPTRHQNGG NFPRSQISVL QNRIEQLEQL LEENHEIISH IKDSVLELTA NAEGPPAMLP YYTVNGSWVV PPEPRPSFFS ISPQDCQFAL GGRGQKPELQ MLTVSEELPF DNVDGGVWRQ GFDISYDPHD WDAEDLQVFV VPHSHNDPGW IKTFDKYYTE QTQHILNSMV SKLQEDPRRR FLWAEVSFFA KWWDNINVQK RAAVRRLVGN GQLEIATGGW VMPDEANSHY FALIDQLIEG HQWLERNLGA TPRSGWAVDP FGYSSTMPYL LRRANLTSML IQRVHYAIKK HFAATHSLEF MWRQTWDSDS STDIFCHMMP FYSYDVPHTC GPDPKICCQF DFKRLPGGRI NCPWKVPPRA ITEANVAERA ALLLDQYRKK SQLFRSNVLL VPLGDDFRYD KPQEWDAQFF NYQRLFDFFN SRPNLHVQAQ FGTLSDYFDA LYKRTGVEPG ARPPGFPVLS GDFFSYADRE DHYWTGYYTS RPFYKSLDRV LEAHLRGAEV LYSLAAAHAR RSGLAGRYPL SDFTLLTEAR RTLGLFQHHD AITGTAKEAV VVDYGVRLLR SLVNLKQVII HAAHYLVLGD KETYHFDPEA PFLQVDDTRL SHDALPERTV IQLDSSPRFV VLFNPLEQER FSMVSLLVNS PRVRVLSEEG QPLAVQISAH WSSATEAVPD VYQVSVPVRL PALGLGVLQL QLGLDGHRTL PSSVRIYLHG RQLSVSRHEA FPLRVIDSGT SDFALSNRYM QVWFSGLTGL LKSIRRVDEE HEQQVDMQVL VYGTRTSKDK SGAYLFLPDG EAKPYVPKEP PVLRVTEGPF FSEVVAYYEH IHQAVRLYNL PGVEGLSLDI SSLVDIRDYV NKELALHIHT DIDSQGIFFT DLNGFQVQPR RYLKKLPLQA NFYPMPVMAY IQDAQKRLTL HTAQALGVSS LKDGQLEVIL DRRLMQDDNR GLGQGLKDNK RTCNRFRLLL ERRTVGSEVQ DSHSTSYPSL LSHLTSMYLN APALALPVAR MQLPGPGLRS FHPLASSLPC DFHLLNLRTL QAEEDTLPSA ETALILHRKG FDCGLEAKNL GFNCTTSQGK VALGSLFHGL DVVFLQPTSL TLLYPLASPS NSTDVYLEPM EIATFRLRLG
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.