Details for: MAP3K9

Gene ID: 4293

Symbol: MAP3K9

Ensembl ID: ENSG00000006432

Description: mitogen-activated protein kinase kinase kinase 9

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 110.4502
    Cell Significance Index: -17.1800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 67.9694
    Cell Significance Index: -17.2400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 13.9340
    Cell Significance Index: -17.1800
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 6.0287
    Cell Significance Index: -16.1500
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 2.5621
    Cell Significance Index: 42.2200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.6345
    Cell Significance Index: 22.3000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.4855
    Cell Significance Index: 297.9900
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 1.2527
    Cell Significance Index: 27.4300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.9001
    Cell Significance Index: 322.8700
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.7471
    Cell Significance Index: 21.3200
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.6560
    Cell Significance Index: 130.1900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.6037
    Cell Significance Index: 16.8700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.5538
    Cell Significance Index: 20.9700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.5207
    Cell Significance Index: 23.0300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.5074
    Cell Significance Index: 34.1200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.4681
    Cell Significance Index: 323.7400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.4622
    Cell Significance Index: 24.0100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4360
    Cell Significance Index: 43.1300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.4163
    Cell Significance Index: 18.8700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3865
    Cell Significance Index: 11.1400
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 0.3471
    Cell Significance Index: 2.8700
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3458
    Cell Significance Index: 312.2300
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.3260
    Cell Significance Index: 4.6400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.2543
    Cell Significance Index: 16.0300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.2458
    Cell Significance Index: 39.9800
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.2355
    Cell Significance Index: 25.6200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2289
    Cell Significance Index: 41.2700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.2243
    Cell Significance Index: 4.8600
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.2242
    Cell Significance Index: 5.6100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.2175
    Cell Significance Index: 5.9200
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.2026
    Cell Significance Index: 12.1600
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.1716
    Cell Significance Index: 2.9400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1125
    Cell Significance Index: 13.8400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0990
    Cell Significance Index: 54.0600
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: 0.0820
    Cell Significance Index: 1.0200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0738
    Cell Significance Index: 14.0400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.0738
    Cell Significance Index: 4.1400
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: 0.0640
    Cell Significance Index: 0.8300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.0489
    Cell Significance Index: 3.3800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0399
    Cell Significance Index: 54.2500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0288
    Cell Significance Index: 18.3200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0268
    Cell Significance Index: 1.2500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0257
    Cell Significance Index: 1.9800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0243
    Cell Significance Index: 44.7300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0242
    Cell Significance Index: 37.3000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0234
    Cell Significance Index: 3.9900
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0218
    Cell Significance Index: 0.7700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0173
    Cell Significance Index: 32.5900
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.0094
    Cell Significance Index: 0.2000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0019
    Cell Significance Index: 0.0500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0021
    Cell Significance Index: -0.1100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0028
    Cell Significance Index: -1.2400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0085
    Cell Significance Index: -1.2400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0101
    Cell Significance Index: -7.4600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0158
    Cell Significance Index: -11.9600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0165
    Cell Significance Index: -12.1200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0189
    Cell Significance Index: -2.4400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0190
    Cell Significance Index: -10.6900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0262
    Cell Significance Index: -11.8900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0287
    Cell Significance Index: -1.3500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0290
    Cell Significance Index: -18.1200
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0419
    Cell Significance Index: -3.1200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0483
    Cell Significance Index: -13.9100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0522
    Cell Significance Index: -6.0800
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0538
    Cell Significance Index: -0.7700
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.0603
    Cell Significance Index: -1.0200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0745
    Cell Significance Index: -8.5400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0784
    Cell Significance Index: -16.5100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0850
    Cell Significance Index: -10.9000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0855
    Cell Significance Index: -5.2500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0955
    Cell Significance Index: -11.2600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0957
    Cell Significance Index: -9.7800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.1079
    Cell Significance Index: -14.8200
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: -0.1085
    Cell Significance Index: -0.7200
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1093
    Cell Significance Index: -3.5800
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1121
    Cell Significance Index: -3.5700
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.1132
    Cell Significance Index: -2.4100
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.1173
    Cell Significance Index: -1.4800
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.1252
    Cell Significance Index: -1.6700
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1263
    Cell Significance Index: -2.6800
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.1379
    Cell Significance Index: -1.2700
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: -0.1402
    Cell Significance Index: -1.4600
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.1450
    Cell Significance Index: -1.5800
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: -0.1482
    Cell Significance Index: -1.4100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1489
    Cell Significance Index: -4.7700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1550
    Cell Significance Index: -16.1400
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.1620
    Cell Significance Index: -4.3400
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.1664
    Cell Significance Index: -3.2900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1731
    Cell Significance Index: -12.2400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1867
    Cell Significance Index: -14.7900
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.2241
    Cell Significance Index: -4.5000
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.2279
    Cell Significance Index: -5.6900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.2440
    Cell Significance Index: -15.7400
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2589
    Cell Significance Index: -9.0700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.2628
    Cell Significance Index: -13.6900
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.2631
    Cell Significance Index: -3.3200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.2657
    Cell Significance Index: -16.3300
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.2734
    Cell Significance Index: -4.0400
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.2907
    Cell Significance Index: -6.2800
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.2990
    Cell Significance Index: -6.2400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** MAP3K9 is a member of the TAK1 family of serine/threonine kinases, which are characterized by their ability to phosphorylate and activate downstream kinases. MAP3K9 is specifically activated by mitogen-activated protein kinases (MAPKs) and is involved in regulating the activity of NF-κB, a transcription factor that plays a crucial role in inflammation and immune responses. MAP3K9 is also capable of autophosphorylation, which is essential for its activation and function. **Pathways and Functions:** MAP3K9 is involved in multiple signaling pathways, including the MAPK cascade, NF-κB signaling, and JNK signaling. These pathways are critical for regulating cellular responses to stress, injury, and inflammation. MAP3K9 plays a key role in modulating the activity of downstream kinases, such as MAPKs and NF-κB, thereby regulating cellular processes such as: 1. **Apoptosis**: MAP3K9 is involved in regulating the activity of caspases, which are essential for initiating apoptosis. 2. **Inflammation**: MAP3K9 modulates the activity of NF-κB, which is a key transcription factor involved in regulating inflammatory responses. 3. **Cell survival**: MAP3K9 is involved in regulating the activity of downstream kinases that are involved in promoting cell survival. **Clinical Significance:** MAP3K9 has been implicated in various diseases, including: 1. **Neurodegenerative disorders**: MAP3K9 has been shown to be involved in regulating the activity of downstream kinases that are involved in neurodegenerative processes, such as Alzheimer's disease and Parkinson's disease. 2. **Inflammatory disorders**: MAP3K9 has been implicated in regulating the activity of NF-κB, which is a key transcription factor involved in inflammatory responses, such as rheumatoid arthritis and multiple sclerosis. 3. **Cancer**: MAP3K9 has been shown to be involved in regulating the activity of downstream kinases that are involved in promoting cell survival and proliferation, which is critical for cancer development and progression. In conclusion, MAP3K9 is a complex enzyme that plays a critical role in regulating cellular signaling pathways, including apoptosis, inflammation, and cell survival. Its dysregulation has been implicated in various diseases, highlighting the importance of MAP3K9 in maintaining cellular homeostasis and preventing disease. Further research is needed to fully understand the mechanisms by which MAP3K9 regulates cellular signaling and to explore its therapeutic potential in various diseases.

Genular Protein ID: 1902031598

Symbol: M3K9_HUMAN

Name: Mitogen-activated protein kinase kinase kinase 9

UniProtKB Accession Codes:

P80192 A3KN85 Q0D2G7 Q6EH31 Q9H2N5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 2 CPTAC 2 CTD 1 ChEBI 13 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 DrugBank 2 DrugCentral 1 EC 3 EMBL 4 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 11 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GuidetoPHARMACOLOGY 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 10 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PIR 1 PIRSF 1 PRINTS 2 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 RefSeq 2 Rhea 6 SABIO-RK 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 15610029

Title: Phosphoregulation of mixed-lineage kinase 1 activity by multiple phosphorylation in the activation loop.

PubMed ID: 15610029

DOI: 10.1021/bi049866y

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8477742

Title: Identification of a new family of human epithelial protein kinases containing two leucine/isoleucine-zipper domains.

PubMed ID: 8477742

DOI: 10.1111/j.1432-1033.1993.tb17810.x

PubMed ID: 11325962

Title: Cep-1347 (KT7515), a semisynthetic inhibitor of the mixed lineage kinase family.

PubMed ID: 11325962

DOI: 10.1074/jbc.m011601200

PubMed ID: 11416147

Title: The MLK family mediates c-Jun N-terminal kinase activation in neuronal apoptosis.

PubMed ID: 11416147

DOI: 10.1128/mcb.21.14.4713-4724.2001

PubMed ID: 11755341

Title: Mixed lineage kinase activity of indolocarbazole analogues.

PubMed ID: 11755341

DOI: 10.1016/s0960-894x(01)00690-4

PubMed ID: 18241037

Title: Genomic profiling of 766 cancer-related genes in archived esophageal normal and carcinoma tissues.

PubMed ID: 18241037

DOI: 10.1002/ijc.23397

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 18714982

Title: Mixed-lineage kinase 1 and mixed-lineage kinase 3 subtype-selective dihydronaphthyl[3,4-a]pyrrolo[3,4-c]carbazole-5-ones: optimization, mixed-lineage kinase 1 crystallography, and oral in vivo activity in 1-methyl-4-phenyltetrahydropyridine models.

PubMed ID: 18714982

DOI: 10.1021/jm8005838

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

Sequence Information:

  • Length: 1104
  • Mass: 121895
  • Checksum: 0F059C867FCE7276
  • Sequence:
    • MEPSRALLGC LASAAAAAPP GEDGAGAGAE EEEEEEEEAA AAVGPGELGC DAPLPYWTAV 
FEYEAAGEDE LTLRLGDVVE VLSKDSQVSG DEGWWTGQLN QRVGIFPSNY VTPRSAFSSR 
CQPGGEDPSC YPPIQLLEID FAELTLEEII GIGGFGKVYR AFWIGDEVAV KAARHDPDED 
ISQTIENVRQ EAKLFAMLKH PNIIALRGVC LKEPNLCLVM EFARGGPLNR VLSGKRIPPD 
ILVNWAVQIA RGMNYLHDEA IVPIIHRDLK SSNILILQKV ENGDLSNKIL KITDFGLARE 
WHRTTKMSAA GTYAWMAPEV IRASMFSKGS DVWSYGVLLW ELLTGEVPFR GIDGLAVAYG 
VAMNKLALPI PSTCPEPFAK LMEDCWNPDP HSRPSFTNIL DQLTTIEESG FFEMPKDSFH 
CLQDNWKHEI QEMFDQLRAK EKELRTWEEE LTRAALQQKN QEELLRRREQ ELAEREIDIL 
ERELNIIIHQ LCQEKPRVKK RKGKFRKSRL KLKDGNRISL PSDFQHKFTV QASPTMDKRK 
SLINSRSSPP ASPTIIPRLR AIQLTPGESS KTWGRSSVVP KEEGEEEEKR APKKKGRTWG 
PGTLGQKELA SGDEGSPQRR EKANGLSTPS ESPHFHLGLK SLVDGYKQWS SSAPNLVKGP 
RSSPALPGFT SLMEMEDEDS EGPGSGESRL QHSPSQSYLC IPFPRGEDGD GPSSDGIHEE 
PTPVNSATST PQLTPTNSLK RGGAHHRRCE VALLGCGAVL AATGLGFDLL EAGKCQLLPL 
EEPEPPAREE KKRREGLFQR SSRPRRSTSP PSRKLFKKEE PMLLLGDPSA SLTLLSLSSI 
SECNSTRSLL RSDSDEIVVY EMPVSPVEAP PLSPCTHNPL VNVRVERFKR DPNQSLTPTH 
VTLTTPSQPS SHRRTPSDGA LKPETLLASR SPSSNGLSPS PGAGMLKTPS PSRDPGEFPR 
LPDPNVVFPP TPRRWNTQQD STLERPKTLE FLPRPRPSAN RQRLDPWWFV SPSHARSTSP 
ANSSSTETPS NLDSCFASSS STVEERPGLP ALLPFQAGPL PPTERTLLDL DAEGQSQDST 
VPLCRAELNT HRPAPYEIQQ EFWS

Genular Protein ID: 468389729

Symbol: B4DZC4_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DZC4

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 2 Gene3D 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 2 SUPFAM 1

Sequence Information:

  • Length: 832
  • Mass: 92259
  • Checksum: AA5CC40FE0C30F9F
  • Sequence:
    • MELTGLEVAL VLILQKVENG DLSNKILKIT DFGLAREWHR TTKMSAAGTY AWMAPEVIRA 
SMFSKGSDVW SYGVLLWELL TGEVPFRGID GLAVAYGVAM NKLALPIPST CPEPFAKLVE 
DCWNPDPHSR PSFTNILDQL TTIEESGFFE MPKDSFHCLQ DNWKHEIQEM FDQLRAKEKE 
LRTWEEELTR AALQQKNQEE LLRRREQELA EREIDILERE LNIIIHQLCQ EKPRVKKRKG 
KFRKSRLKLK DGNRISLPSD FQHKFTVQAS PTMDKRKSLI NSRSSPPASP TIIPRLRAIQ 
LTPGESSKTW GRSSVVPKEE GEEGEKRAPK KKGRTWGPGT LGQKELASGD EGLKSLVDGY 
KQWSSSAPNL VKGPRSSPAL PGFTSLMEMA LLAASWVVPI DIEEDEDSEG PGSGESRLQH 
SPSQSYLCIP FPRGEDGDGP SSDGIHEEPT PVNSATSTPQ LTPTNSLKRG GAHHRRCEVA 
LLGCGAVLAA TGLGFDLLEA GKCQLLPLEE PEPPAREEKK RREGLFQRSS RPRRSTSPPS 
RKLFKKEEPM LLLGDPSASL TLLSLSSISE CNSTRSLLRS DSDEIVVYEM PVSPVEAPPL 
SPCTHNPLVN VRVERFKRDP NQSLTPTHVT LTTPSQPSSH RRTPSDGALK PETLLASRSP 
SSNGLSPSPG AGMLKTPSPS RDPGEFPRLP DPNVVFPPTP RRWNTQQDST LERPKTLEFL 
PRPRPSANRQ RLDPWWFVSP SHARSTSPAN SSSTETPSNL DSCFASSSST VEERPGLPAL 
LPFQAGPLPP TERTLLDLDA EGQSQDSTVP LCRAELNTHR PAPYEIQQEF WS

Genular Protein ID: 2296070448

Symbol: J3KPI6_HUMAN

Name: N/A

UniProtKB Accession Codes:

J3KPI6

Database IDs:

ARBA 9 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChEBI 13 ChiTaRS 1 DNASU 1 DisGeNET 1 EC 2 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 2 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 10 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PIRSR 2 PRINTS 2 PROSITE 6 PROSITE-ProRule 2 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 Rhea 6 SAM 2 SMART 2 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 12508121

Title: The DNA sequence and analysis of human chromosome 14.

PubMed ID: 12508121

DOI: 10.1038/nature01348

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.M800588-MCP200

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

Sequence Information:

  • Length: 1081
  • Mass: 119380
  • Checksum: DF85CB9FB6003933
  • Sequence:
    • MEPSRALLGC LASAAAAAPP GEDGAGAGAE EEEEEEEEAA AAVGPGELGC DAPLPYWTAV 
FEYEAAGEDE LTLRLGDVVE VLSKDSQVSG DEGWWTGQLN QRVGIFPSNY VTPRSAFSSR 
CQPGGEDPSC YPPIQLLEID FAELTLEEII GIGGFGKVYR AFWIGDEVAV KAARHDPDED 
ISQTIENVRQ EAKLFAMLKH PNIIALRGVC LKEPNLCLVM EFARGGPLNR VLSGKRIPPD 
ILVNWAVQIA RGMNYLHDEA IVPIIHRDLK SSNILILQKV ENGDLSNKIL KITDFGLARE 
WHRTTKMSAA GTYAWMAPEV IRASMFSKGS DVWSYGVLLW ELLTGEVPFR GIDGLAVAYG 
VAMNKLALPI PSTCPEPFAK LMEDCWNPDP HSRPSFTNIL DQLTTIEESG FFEMPKDSFH 
CLQDNWKHEI QEMFDQLRAK EKELRTWEEE LTRAALQQKN QEELLRRREQ ELAEREIDIL 
ERELNIIIHQ LCQEKPRVKK RKGKFRKSRL KLKDGNRISL PSDFQHKFTV QASPTMDKRK 
SLINSRSSPP ASPTIIPRLR AIQLTPGESS KTWGRSSVVP KEEGEEEEKR APKKKGRTWG 
PGTLGQKELA SGDEGLKSLV DGYKQWSSSA PNLVKGPRSS PALPGFTSLM EMEDEDSEGP 
GSGESRLQHS PSQSYLCIPF PRGEDGDGPS SDGIHEEPTP VNSATSTPQL TPTNSLKRGG 
AHHRRCEVAL LGCGAVLAAT GLGFDLLEAG KCQLLPLEEP EPPAREEKKR REGLFQRSSR 
PRRSTSPPSR KLFKKEEPML LLGDPSASLT LLSLSSISEC NSTRSLLRSD SDEIVVYEMP 
VSPVEAPPLS PCTHNPLVNV RVERFKRDPN QSLTPTHVTL TTPSQPSSHR RTPSDGALKP 
ETLLASRSPS SNGLSPSPGA GMLKTPSPSR DPGEFPRLPD PNVVFPPTPR RWNTQQDSTL 
ERPKTLEFLP RPRPSANRQR LDPWWFVSPS HARSTSPANS SSTETPSNLD SCFASSSSTV 
EERPGLPALL PFQAGPLPPT ERTLLDLDAE GQSQDSTVPL CRAELNTHRP APYEIQQEFW 
S

Genular Protein ID: 354865631

Symbol: G3V347_HUMAN

Name: N/A

UniProtKB Accession Codes:

G3V347

Database IDs:

AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 2 Gene3D 1 GeneTree 1 HGNC 1 InterPro 5 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 2 PeptideAtlas 2 Pfam 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 2 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 12508121

Title: The DNA sequence and analysis of human chromosome 14.

PubMed ID: 12508121

DOI: 10.1038/nature01348

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.M800588-MCP200

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

Sequence Information:

  • Length: 837
  • Mass: 92827
  • Checksum: 8819E2AF68E5CB2A
  • Sequence:
    • MSAAGTYAWM APEVIRASMF SKGSDVWSYG VLLWELLTGE VPFRGIDGLA VAYGVAMNKL 
ALPIPSTCPE PFAKLMEDCW NPDPHSRPSF TNILDQLTTI EESGFFEMPK DSFHCLQDNW 
KHEIQEMFDQ LRAKEKELRT WEEELTRAAL QQKNQEELLR RREQELAERE IDILERELNI 
IIHQLCQEKP RVKKRKGKFR KSRLKLKDGN RISLPSDFQH KFTVQASPTM DKRKSLINSR 
SSPPASPTII PRLRAIQCET VSQISWGQNT QGHLSPALSS HRLVQACSIH NFCHLSSTMC 
IYMHILTPGE SSKTWGRSSV VPKEEGEEEE KRAPKKKGRT WGPGTLGQKE LASGDEGLKS 
LVDGYKQWSS SAPNLVKGPR SSPALPGFTS LMEMALLAAS WVVPIDIEED EDSEGPGSGE 
SRLQHSPSQS YLCIPFPRGE DGDGPSSDGI HEEPTPVNSA TSTPQLTPTN SLKRGGAHHR 
RCEVALLGCG AVLAATGLGF DLLEAGKCQL LPLEEPEPPA REEKKRREGL FQRSSRPRRS 
TSPPSRKLFK KEEPMLLLGD PSASLTLLSL SSISECNSTR SLLRSDSDEI VVYEMPVSPV 
EAPPLSPCTH NPLVNVRVER FKRDPNQSLT PTHVTLTTPS QPSSHRRTPS DGALKPETLL 
ASRSPSSNGL SPSPGAGMLK TPSPSRDPGE FPRLPDPNVV FPPTPRRWNT QQDSTLERPK 
TLEFLPRPRP SANRQRLDPW WFVSPSHARS TSPANSSSTE TPSNLDSCFA SSSSTVEERP 
GLPALLPFQA GPLPPTERTL LDLDAEGQSQ DSTVPLCRAE LNTHRPAPYE IQQEFWS

Genular Protein ID: 4155721965

Symbol: Q8NEB1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q8NEB1

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 2 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PeptideAtlas 1 PharmGKB 1 RefSeq 4 SAM 2

Sequence Information:

  • Length: 373
  • Mass: 40924
  • Checksum: 0FB62AD6E1340013
  • Sequence:
    • QLTPTNSLKR GGAHHRRCEV ALLGCGAVLA ATGLGFDLLE AGKCQLLPLE EPEPPAREEK 
KRREGLFQRS SRPRRSTSPP SRKLFKKEEP MLLLGDPSAS LTLLSLSSIS ECNSTRSLLR 
SDSDEIVVYE MPVSPVEAPP LSPCTHNPLV NVRVERFKRD PNQSLTPTHV TLTTPSQPSS 
HRRTPSDGAL KPETLLASRS PSSNGLSPSP GAGMLKTPSP SRDPGEFPRL PDPNVVFPPT 
PRRWNTQQDS TLERPKTLEF LPRPRPSANR QRLDPWWFVS PSHARSTSPA NSSSTETPSN 
LDSCFASSSS TVEERPGLPA LLPFQAGPLP PTERTLLDLD AEGQSQDSTV PLCRAELNTH 
RPAPYEIQQE FWS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.