Details for: MAP3K11

Gene ID: 4296

Symbol: MAP3K11

Ensembl ID: ENSG00000173327

Description: mitogen-activated protein kinase kinase kinase 11

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 138.5449
    Cell Significance Index: -21.5500
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 84.8041
    Cell Significance Index: -21.5100
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 59.8863
    Cell Significance Index: -24.6700
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 54.6045
    Cell Significance Index: -25.7800
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 49.4571
    Cell Significance Index: -25.4400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 19.0599
    Cell Significance Index: -23.5000
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 8.6828
    Cell Significance Index: -23.2600
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 6.1074
    Cell Significance Index: -24.1000
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 6.0004
    Cell Significance Index: -18.4300
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 5.1494
    Cell Significance Index: -11.2700
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.7356
    Cell Significance Index: 23.6800
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.2420
    Cell Significance Index: 135.0900
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.1934
    Cell Significance Index: 71.6500
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 1.0926
    Cell Significance Index: 20.2000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.0890
    Cell Significance Index: 49.3600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 1.0782
    Cell Significance Index: 23.3600
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.9224
    Cell Significance Index: 26.5800
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 0.8505
    Cell Significance Index: 15.0300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.8228
    Cell Significance Index: 42.7400
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.8169
    Cell Significance Index: 12.2400
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.7729
    Cell Significance Index: 8.7800
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.7487
    Cell Significance Index: 20.3800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.6606
    Cell Significance Index: 131.1000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.5127
    Cell Significance Index: 63.0400
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.4702
    Cell Significance Index: 32.5200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.4666
    Cell Significance Index: 30.1000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.4594
    Cell Significance Index: 82.8200
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3244
    Cell Significance Index: 52.7600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.3185
    Cell Significance Index: 173.9200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.2928
    Cell Significance Index: 7.3200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.2737
    Cell Significance Index: 12.7600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.2652
    Cell Significance Index: 117.2400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.2288
    Cell Significance Index: 8.0400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.2248
    Cell Significance Index: 10.5700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2175
    Cell Significance Index: 41.3900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.2085
    Cell Significance Index: 41.8300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.1503
    Cell Significance Index: 3.2000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.1415
    Cell Significance Index: 8.9200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.1369
    Cell Significance Index: 16.1400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1303
    Cell Significance Index: 12.8900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1255
    Cell Significance Index: 45.0300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.1120
    Cell Significance Index: 8.3500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1075
    Cell Significance Index: 14.7600
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 0.1065
    Cell Significance Index: 0.7700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0929
    Cell Significance Index: 12.0000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0674
    Cell Significance Index: 46.6400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0603
    Cell Significance Index: 7.7300
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.0449
    Cell Significance Index: 1.2000
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.0182
    Cell Significance Index: 0.1100
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.0123
    Cell Significance Index: 0.6500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.0087
    Cell Significance Index: 0.2800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0059
    Cell Significance Index: 0.4200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0012
    Cell Significance Index: 2.2100
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0034
    Cell Significance Index: -0.0900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0089
    Cell Significance Index: -16.4900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0118
    Cell Significance Index: -8.9100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0129
    Cell Significance Index: -19.7900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0135
    Cell Significance Index: -2.3000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0157
    Cell Significance Index: -21.3600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0162
    Cell Significance Index: -1.6500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0188
    Cell Significance Index: -13.8200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0251
    Cell Significance Index: -18.6000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0258
    Cell Significance Index: -16.3700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0304
    Cell Significance Index: -13.8200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0330
    Cell Significance Index: -3.7800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0391
    Cell Significance Index: -22.0700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.0407
    Cell Significance Index: -1.4200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0436
    Cell Significance Index: -27.2000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0699
    Cell Significance Index: -5.3700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0712
    Cell Significance Index: -20.4900
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.0805
    Cell Significance Index: -0.9600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0824
    Cell Significance Index: -11.9800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0877
    Cell Significance Index: -2.4500
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.1149
    Cell Significance Index: -3.0800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1255
    Cell Significance Index: -26.4300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1262
    Cell Significance Index: -14.7100
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.1577
    Cell Significance Index: -2.5300
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1723
    Cell Significance Index: -4.5300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1856
    Cell Significance Index: -11.4100
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1994
    Cell Significance Index: -11.1900
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.2093
    Cell Significance Index: -3.0100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2203
    Cell Significance Index: -22.9400
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.2336
    Cell Significance Index: -3.9100
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.2601
    Cell Significance Index: -6.6500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2826
    Cell Significance Index: -22.3800
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.2927
    Cell Significance Index: -2.7000
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.2961
    Cell Significance Index: -6.8400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.3025
    Cell Significance Index: -20.3400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.3052
    Cell Significance Index: -18.7100
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.3214
    Cell Significance Index: -9.4400
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.3400
    Cell Significance Index: -3.5200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.3812
    Cell Significance Index: -16.8600
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.4049
    Cell Significance Index: -6.8100
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.4249
    Cell Significance Index: -13.4400
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.4489
    Cell Significance Index: -17.0000
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -0.5361
    Cell Significance Index: -7.5200
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.5363
    Cell Significance Index: -9.1900
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.5386
    Cell Significance Index: -19.7700
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.5418
    Cell Significance Index: -18.9800
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.5681
    Cell Significance Index: -11.7900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** MAP3K11 is a member of the MAP3K family, which consists of serine/threonine kinases that regulate the MAPK signaling pathway. This gene is characterized by its ability to phosphorylate and activate downstream targets, including MAPK1 and MAPK3, which are involved in various cellular processes. MAP3K11 has been shown to be a positive regulator of the JNK and Jun kinase pathways, and its activation can lead to the promotion of apoptosis and cell death. **Pathways and Functions:** MAP3K11 is involved in several signaling pathways, including: 1. **MAPK signaling pathway**: MAP3K11 phosphorylates and activates MAPK1 and MAPK3, which are involved in various cellular processes, including cell cycle regulation, apoptosis, and inflammation. 2. **JNK and Jun kinase pathways**: MAP3K11 is a positive regulator of the JNK and Jun kinase pathways, which are involved in cell death, inflammation, and immune responses. 3. **Raf activation**: MAP3K11 can activate Raf, a key regulator of the MAPK signaling pathway, leading to the promotion of cell proliferation and survival. 4. **Apoptotic process**: MAP3K11 can promote apoptosis by phosphorylating and activating pro-apoptotic proteins, such as Bax and Bak. 5. **Neuron apoptotic process**: MAP3K11 has been shown to play a role in the regulation of neuron apoptosis, which is involved in neurodegenerative disorders. **Clinical Significance:** MAP3K11 has been implicated in several diseases, including: 1. **Cancer**: MAP3K11 is often overexpressed in various types of cancer, including breast, lung, and colon cancer, and is associated with poor prognosis. 2. **Cardiovascular diseases**: MAP3K11 has been implicated in the regulation of cardiovascular diseases, including hypertension, atherosclerosis, and cardiac arrhythmias. 3. **Neurodegenerative disorders**: MAP3K11 has been shown to play a role in the regulation of neuron apoptosis, which is involved in neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease. 4. **Inflammatory disorders**: MAP3K11 has been implicated in the regulation of inflammatory responses, which is involved in various inflammatory disorders, including rheumatoid arthritis and inflammatory bowel disease. In conclusion, MAP3K11 is a critical regulator of the MAPK signaling pathway and has been implicated in various diseases, including cancer, cardiovascular diseases, and neurodegenerative disorders. Further studies are needed to fully understand the mechanisms by which MAP3K11 regulates cellular processes and to explore its potential as a therapeutic target.

Genular Protein ID: 2588121216

Symbol: M3K11_HUMAN

Name: Mitogen-activated protein kinase kinase kinase 11

UniProtKB Accession Codes:

Q16584 B4DS76 Q53H00 Q59F06 Q6P2G4

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CORUM 1 CPTAC 8 CTD 1 ChEBI 13 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 DrugCentral 1 EC 3 EMBL 9 Ensembl 2 ExpressionAtlas 1 GO 25 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 10 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 4 PIR 1 PIRSF 1 PRINTS 2 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 7 RefSeq 1 Rhea 6 SABIO-RK 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8195146

Title: Identification and characterization of SPRK, a novel src-homology 3 domain-containing proline-rich kinase with serine/threonine kinase activity.

PubMed ID: 8195146

DOI: 10.1016/s0021-9258(17)36578-x

PubMed ID: 8183572

Title: MLK-3: identification of a widely-expressed protein kinase bearing an SH3 domain and a leucine zipper-basic region domain.

PubMed ID: 8183572

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9003778

Title: MLK-3 activates the SAPK/JNK and p38/RK pathways via SEK1 and MKK3/6.

PubMed ID: 9003778

DOI: 10.1002/j.1460-2075.1996.tb01094.x

PubMed ID: 9829970

Title: Dimerization via tandem leucine zippers is essential for the activation of the mitogen-activated protein kinase kinase kinase, MLK-3.

PubMed ID: 9829970

DOI: 10.1074/jbc.273.49.32408

PubMed ID: 11053428

Title: The kinase activation loop is the key to mixed lineage kinase-3 activation via both autophosphorylation and hematopoietic progenitor kinase 1 phosphorylation.

PubMed ID: 11053428

DOI: 10.1074/jbc.m004092200

PubMed ID: 11969422

Title: Identification of in vivo phosphorylation sites of MLK3 by mass spectrometry and phosphopeptide mapping.

PubMed ID: 11969422

DOI: 10.1021/bi016075c

PubMed ID: 12529434

Title: A new identity for MLK3 as an NIMA-related, cell cycle-regulated kinase that is localized near centrosomes and influences microtubule organization.

PubMed ID: 12529434

DOI: 10.1091/mbc.e02-02-0115

PubMed ID: 15258589

Title: MLK3 is required for mitogen activation of B-Raf, ERK and cell proliferation.

PubMed ID: 15258589

DOI: 10.1038/ncb1152

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

Sequence Information:

  • Length: 847
  • Mass: 92688
  • Checksum: AFB6E930EA281C15
  • Sequence:
    • MEPLKSLFLK SPLGSWNGSG SGGGGGGGGG RPEGSPKAAG YANPVWTALF DYEPSGQDEL 
ALRKGDRVEV LSRDAAISGD EGWWAGQVGG QVGIFPSNYV SRGGGPPPCE VASFQELRLE 
EVIGIGGFGK VYRGSWRGEL VAVKAARQDP DEDISVTAES VRQEARLFAM LAHPNIIALK 
AVCLEEPNLC LVMEYAAGGP LSRALAGRRV PPHVLVNWAV QIARGMHYLH CEALVPVIHR 
DLKSNNILLL QPIESDDMEH KTLKITDFGL AREWHKTTQM SAAGTYAWMA PEVIKASTFS 
KGSDVWSFGV LLWELLTGEV PYRGIDCLAV AYGVAVNKLT LPIPSTCPEP FAQLMADCWA 
QDPHRRPDFA SILQQLEALE AQVLREMPRD SFHSMQEGWK REIQGLFDEL RAKEKELLSR 
EEELTRAARE QRSQAEQLRR REHLLAQWEL EVFERELTLL LQQVDRERPH VRRRRGTFKR 
SKLRARDGGE RISMPLDFKH RITVQASPGL DRRRNVFEVG PGDSPTFPRF RAIQLEPAEP 
GQAWGRQSPR RLEDSSNGER RACWAWGPSS PKPGEAQNGR RRSRMDEATW YLDSDDSSPL 
GSPSTPPALN GNPPRPSLEP EEPKRPVPAE RGSSSGTPKL IQRALLRGTA LLASLGLGRD 
LQPPGGPGRE RGESPTTPPT PTPAPCPTEP PPSPLICFSL KTPDSPPTPA PLLLDLGIPV 
GQRSAKSPRR EEEPRGGTVS PPPGTSRSAP GTPGTPRSPP LGLISRPRPS PLRSRIDPWS 
FVSAGPRPSP LPSPQPAPRR APWTLFPDSD PFWDSPPANP FQGGPQDCRA QTKDMGAQAP 
WVPEAGP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.