Details for: MPP2

Gene ID: 4355

Symbol: MPP2

Ensembl ID: ENSG00000108852

Description: MAGUK p55 scaffold protein 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 123.4368
    Cell Significance Index: -19.2000
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 75.8545
    Cell Significance Index: -19.2400
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 2.8101
    Cell Significance Index: 21.6600
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 2.4856
    Cell Significance Index: -5.4400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 1.9619
    Cell Significance Index: 42.5100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.1946
    Cell Significance Index: 239.6400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.7182
    Cell Significance Index: 71.0500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.6708
    Cell Significance Index: 605.7000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.6254
    Cell Significance Index: 224.3100
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: 0.4917
    Cell Significance Index: 5.9600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.4752
    Cell Significance Index: 328.6600
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.4535
    Cell Significance Index: 5.6300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.4462
    Cell Significance Index: 30.0000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3622
    Cell Significance Index: 58.9100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3152
    Cell Significance Index: 59.9800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.2903
    Cell Significance Index: 15.2400
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.2502
    Cell Significance Index: 27.2200
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.2206
    Cell Significance Index: 6.3000
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.2124
    Cell Significance Index: 4.6500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.1201
    Cell Significance Index: 7.3800
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0834
    Cell Significance Index: 1.4300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0750
    Cell Significance Index: 5.7600
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.0644
    Cell Significance Index: 4.4600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0404
    Cell Significance Index: 62.2200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0402
    Cell Significance Index: 75.7300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0276
    Cell Significance Index: 37.5400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0175
    Cell Significance Index: 32.3500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.0104
    Cell Significance Index: 0.4600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0083
    Cell Significance Index: 3.7500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0011
    Cell Significance Index: 0.6900
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0006
    Cell Significance Index: 0.0200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0066
    Cell Significance Index: -0.1900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0145
    Cell Significance Index: -6.3900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0171
    Cell Significance Index: -2.4900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0177
    Cell Significance Index: -13.1000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0228
    Cell Significance Index: -12.4700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0253
    Cell Significance Index: -18.5600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0265
    Cell Significance Index: -14.9300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0278
    Cell Significance Index: -21.0400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0326
    Cell Significance Index: -20.3600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0329
    Cell Significance Index: -1.4900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0399
    Cell Significance Index: -1.5100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0404
    Cell Significance Index: -1.0100
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.0485
    Cell Significance Index: -2.9100
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0488
    Cell Significance Index: -1.1700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0561
    Cell Significance Index: -16.1400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0571
    Cell Significance Index: -11.3300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0829
    Cell Significance Index: -14.1500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0845
    Cell Significance Index: -15.2400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0932
    Cell Significance Index: -19.6400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.1110
    Cell Significance Index: -15.2400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.1165
    Cell Significance Index: -14.3200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1218
    Cell Significance Index: -7.4700
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.1275
    Cell Significance Index: -16.3500
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1465
    Cell Significance Index: -3.1100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.1465
    Cell Significance Index: -3.1200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1472
    Cell Significance Index: -19.0200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1486
    Cell Significance Index: -15.4700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1520
    Cell Significance Index: -17.9200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1545
    Cell Significance Index: -4.9500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1569
    Cell Significance Index: -18.2800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1576
    Cell Significance Index: -18.0500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1722
    Cell Significance Index: -17.5900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1821
    Cell Significance Index: -5.0900
  • Cell Name: OFF-bipolar cell (CL0000750)
    Fold Change: -0.1862
    Cell Significance Index: -1.6400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2024
    Cell Significance Index: -11.3600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.2078
    Cell Significance Index: -14.7000
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.2322
    Cell Significance Index: -2.5300
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.2346
    Cell Significance Index: -3.1300
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2366
    Cell Significance Index: -18.7400
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.2396
    Cell Significance Index: -4.8100
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2496
    Cell Significance Index: -7.9500
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2518
    Cell Significance Index: -18.7700
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2831
    Cell Significance Index: -9.2700
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.2898
    Cell Significance Index: -5.7300
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.2926
    Cell Significance Index: -4.1900
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.2941
    Cell Significance Index: -6.3600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.3040
    Cell Significance Index: -19.1600
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: -0.3080
    Cell Significance Index: -3.4800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.3085
    Cell Significance Index: -19.9000
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.3148
    Cell Significance Index: -6.5300
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.3252
    Cell Significance Index: -16.9400
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.3443
    Cell Significance Index: -12.0600
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.3489
    Cell Significance Index: -4.0700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.3661
    Cell Significance Index: -17.0700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.3669
    Cell Significance Index: -12.7500
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.3769
    Cell Significance Index: -9.1300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.3867
    Cell Significance Index: -18.1800
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.4034
    Cell Significance Index: -6.4000
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.4053
    Cell Significance Index: -17.6200
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.4090
    Cell Significance Index: -5.1000
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.4193
    Cell Significance Index: -10.4600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.4339
    Cell Significance Index: -22.5400
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.4434
    Cell Significance Index: -3.6600
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.4581
    Cell Significance Index: -9.5600
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.4589
    Cell Significance Index: -4.3500
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.4676
    Cell Significance Index: -5.9000
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.4701
    Cell Significance Index: -5.0400
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.4873
    Cell Significance Index: -17.8900
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.4936
    Cell Significance Index: -8.2600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Scaffold Protein Function:** MPP2 acts as a scaffold protein, facilitating the assembly and organization of signaling complexes through its multiple protein-protein interaction domains. 2. **Cellular Localization:** MPP2 is primarily localized to the plasma membrane, postsynaptic density, and cytoskeleton, suggesting its involvement in cell-cell junctions, synaptic transmission, and cytoskeletal dynamics. 3. **Diverse Expression Pattern:** MPP2 is expressed in various cell types, including neurons, epithelial cells, and germ cells, indicating its potential role in different cellular processes and tissues. 4. **Protein Interactions:** MPP2 interacts with a range of proteins, including guanylate kinases, G-proteins, and adaptor proteins, suggesting its involvement in various signaling pathways. **Pathways and Functions:** 1. **Excitatory Postsynaptic Potential (EPSP):** MPP2 is involved in the regulation of EPSP, a critical component of synaptic plasticity, through its interaction with postsynaptic density proteins. 2. **Long-term Synaptic Potentiation (LTP):** MPP2 plays a role in the maintenance of LTP, a long-term form of synaptic plasticity, through its interaction with synaptic proteins. 3. **Cytoskeleton Dynamics:** MPP2 regulates cytoskeletal dynamics, including actin filament organization and microtubule stability, through its interaction with cytoskeletal proteins. 4. **Cell-cell Junctions:** MPP2 is involved in the regulation of cell-cell junctions, including adherens junctions and tight junctions, through its interaction with junctional proteins. **Clinical Significance:** The dysregulation of MPP2 has been implicated in various neurological and psychiatric disorders, including Alzheimer's disease, Parkinson's disease, and schizophrenia. Further research is needed to elucidate the functional significance of MPP2 in these disorders and to explore its potential as a therapeutic target. In conclusion, MPP2 is a multifunctional scaffold protein that plays a critical role in regulating various cellular processes, including cell-cell junctions, cytoskeleton dynamics, and synaptic plasticity. Its dysregulation has been implicated in various neurological and psychiatric disorders, highlighting the need for further research into its functional significance and potential therapeutic applications.

Genular Protein ID: 3908758371

Symbol: MPP2_HUMAN

Name: MAGUK p55 subfamily member 2

UniProtKB Accession Codes:

Q14168 B4DGE9 B4DRJ0 B7Z3G8 E7EV80 E7EV91 E7EX01 Q53ES9 Q5CZB9 Q9BQJ2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 6 CDD 3 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 9 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 11 Gene3D 4 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 13 KEGG 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 1 PRO 1 PROSITE 5 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 6 Pumba 1 RNAct 1 RefSeq 9 SMART 4 SMR 1 STRING 1 SUPFAM 4 SignaLink 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7590743

Title: A gene (DLG2) located at 17q12-q21 encodes a new homologue of the Drosophila tumor suppressor dlg-A.

PubMed ID: 7590743

DOI: 10.1006/geno.1995.1101

PubMed ID: 11230166

Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

PubMed ID: 11230166

DOI: 10.1101/gr.gr1547r

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19665017

Title: The PDZ protein MPP2 interacts with c-Src in epithelial cells.

PubMed ID: 19665017

DOI: 10.1016/j.yexcr.2009.07.028

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

Sequence Information:

  • Length: 576
  • Mass: 64581
  • Checksum: A08E858EA646A305
  • Sequence:
    • MPVAATNSET AMQQVLDNLG SLPSATGAAE LDLIFLRGIM ESPIVRSLAK VIMVLWFMQQ 
NVFVPMKYML KYFGAHERLE ETKLEAVRDN NLELVQEILR DLAHVAEQSS TAAELAHILQ 
EPHFQSLLET HDSVASKTYE TPPPSPGLDP TFSNQPVPPD AVRMVGIRKT AGEHLGVTFR 
VEGGELVIAR ILHGGMVAQQ GLLHVGDIIK EVNGQPVGSD PRALQELLRN ASGSVILKIL 
PSYQEPHLPR QVFVKCHFDY DPARDSLIPC KEAGLRFNAG DLLQIVNQDD ANWWQACHVE 
GGSAGLIPSQ LLEEKRKAFV KRDLELTPNS GTLCGSLSGK KKKRMMYLTT KNAEFDRHEL 
LIYEEVARMP PFRRKTLVLI GAQGVGRRSL KNKLIMWDPD RYGTTVPYTS RRPKDSEREG 
QGYSFVSRGE MEADVRAGRY LEHGEYEGNL YGTRIDSIRG VVAAGKVCVL DVNPQAVKVL 
RTAEFVPYVV FIEAPDFETL RAMNRAALES GISTKQLTEA DLRRTVEESS RIQRGYGHYF 
DLCLVNSNLE RTFRELQTAM EKLRTEPQWV PVSWVY

Genular Protein ID: 4042492172

Symbol: D3DX49_HUMAN

Name: N/A

UniProtKB Accession Codes:

D3DX49

Database IDs:

ARBA 2 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 5 Ensembl 2 Gene3D 4 GeneTree 1 HGNC 1 InterPro 13 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 9 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 4 Proteomes 2 ProteomicsDB 1 RefSeq 1 SMART 4 SUPFAM 4 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

Sequence Information:

  • Length: 576
  • Mass: 64586
  • Checksum: A38816D4A0D5F904
  • Sequence:
    • MPVAATNSET AMQQVLDNLG SLPSATGAAE LDLIFLRGIM ESPIVRSLAK VIMVLWFMQQ 
NVFVPMKYML KYFGAHERLE ETKLEAVRDN NLELVQEILR DLAQLAEQSS TAAELAHILQ 
EPHFQSLLET HDSVASKTYE TPPPSPGLDP TFSNQPVPPD AVRMVGIRKT AGEHLGVTFR 
VEGGELVIAR ILHGGMVAQQ GLLHVGDIIK EVNGQPVGSD PRALQELLRN ASGSVILKIL 
PSYQEPHLPR QVFVKCHFDY DPARDSLIPC KEAGLRFNAG DLLQIVNQDD ANWWQACHVE 
GGSAGLIPSQ LLEEKRKAFV KRDLELTPNS GTLCGSLSGK KKKRMMYLTT KNAEFDRHEL 
LIYEEVARMP PFRRKTLVLI GAQGVGRRSL KNKLIMWDPD RYGTTVPYTS RRPKDSEREG 
QGYSFVSRGE MEADVRAGRY LEHGEYEGNL YGTRIDSIRG VVAAGKVCVL DVNPQAVKVL 
RTAEFVPYVV FIEAPDFETL RAMNRAALES GISTKQLTEA DLRRTVEESS RIQRGYGHYF 
DLCLVNSNLE RTFRELQTAM EKLRTEPQWV PVSWVY

Genular Protein ID: 596673077

Symbol: B4DRL7_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DRL7

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 2 Gene3D 4 InterPro 13 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 9 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 4 RefSeq 1 SMART 4 SUPFAM 4

Sequence Information:

  • Length: 569
  • Mass: 63267
  • Checksum: 02F8CAE46DFEDFE1
  • Sequence:
    • MAGSPGSGVS LEGISLESSE EAELQREAMQ QVLDNLGSLP SATGAAELDL IFLRGIMESP 
IVRSLAKAHE RLEETKLEAV RDNNLELVQE ILRDLAQLAE QSSTAAELAH ILQEPHFQSL 
LETHDSVASK TYETPPPSPG LDPTFSNQPV PPDAVRMVGI RKTAGEHLGV TFRVEGGELV 
IARILHGGMV AQQGLLHVGD IIKEVNGQPV GSDPRALQEL LRNASGSVIL KILPSYQEPH 
LPRQVFVKCH FDYDPARDSL IPCKEAGLRF NAGDLLQIVN QDDANWWQAC HVEGGSAGLI 
PSQLLEEKRK AFVKRDLELT PNSGTLCGSL SGKKKKRMMY LTTKNAEFDR HELLIYEEVA 
RMPPFRRKTL VLIGAQGVGR RSLKNKLIMW DPDRYGTTVP YTSRRPKDSE REGQGYSFVS 
RGEMEADVRA GRYLEHGEYE GNLYGTRIDS IRGVVAAGKV CVLDVNPQAV KVLRTAEFVP 
YVVFIEAPDF ETLRAMNRAA LESGISTKQL TEADLRRTVE ESSRIQRGYG HYFDLCLVNS 
NLERTFCELQ TAMEKLRTEP QWVPVSWVY

Genular Protein ID: 4282376811

Symbol: B4DZ84_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DZ84

Database IDs:

ARBA 2 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 5 Ensembl 4 Gene3D 4 GeneTree 1 HGNC 1 InterPro 13 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 9 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 4 Proteomes 2 ProteomicsDB 1 RefSeq 3 SMART 4 SUPFAM 4 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

Sequence Information:

  • Length: 541
  • Mass: 60517
  • Checksum: 80D2722228DE6698
  • Sequence:
    • MQQVLDNLGS LPSATGAAEL DLIFLRGIME SPIVRSLAKA HERLEETKLE AVRDNNLELV 
QEILRDLAQL AEQSSTAAEL AHILQEPHFQ SLLETHDSVA SKTYETPPPS PGLDPTFSNQ 
PVPPDAVRMV GIRKTAGEHL GVTFRVEGGE LVIARILHGG MVAQQGLLHV GDIIKEVNGQ 
PVGSDPRALQ ELLRNASGSV ILKILPSYQE PHLPRQVFVK CHFDYDPARD SLIPCKEAGL 
RFNAGDLLQI VNQDDANWWQ ACHVEGGSAG LIPSQLLEEK RKAFVKRDLE LTPNSGTLCG 
SLSGKKKKRM MYLTTKNAEF DRHELLIYEE VARMPPFRRK TLVLIGAQGV GRRSLKNKLI 
MWDPDRYGTT VPYTSRRPKD SEREGQGYSF VSRGEMEADV RAGRYLEHGE YEGNLYGTRI 
DSIRGVVAAG KVCVLDVNPQ AVKVLRTAEF VPYVVFIEAP DFETLRAMNR AALESGISTK 
QLTEADLRRT VEESSRIQRG YGHYFDLCLV NSNLERTFRE LQTAMEKLRT EPQWVPVSWV 
Y

Genular Protein ID: 4083481167

Symbol: A0A0C4DH75_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0C4DH75

Database IDs:

ARBA 2 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 2 ExpressionAtlas 1 Gene3D 4 GeneTree 1 HGNC 1 InterPro 13 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 9 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 4 Proteomes 2 ProteomicsDB 1 RefSeq 1 SMART 4 SMR 1 SUPFAM 4 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

Sequence Information:

  • Length: 597
  • Mass: 66807
  • Checksum: 2E02799F7D1F2335
  • Sequence:
    • MSWAPPPQVG QNLRSQTVLR ILNGMEDLMW VAMEERRFRA LASFTMPVAA TNSETAMQQV 
LDNLGSLPSA TGAAELDLIF LRGIMESPIV RSLAKAHERL EETKLEAVRD NNLELVQEIL 
RDLAQLAEQS STAAELAHIL QEPHFQSLLE THDSVASKTY ETPPPSPGLD PTFSNQPVPP 
DAVRMVGIRK TAGEHLGVTF RVEGGELVIA RILHGGMVAQ QGLLHVGDII KEVNGQPVGS 
DPRALQELLR NASGSVILKI LPSYQEPHLP RQVFVKCHFD YDPARDSLIP CKEAGLRFNA 
GDLLQIVNQD DANWWQACHV EGGSAGLIPS QLLEEKRKAF VKRDLELTPN SGTLCGSLSG 
KKKKRMMYLT TKNAEFDRHE LLIYEEVARM PPFRRKTLVL IGAQGVGRRS LKNKLIMWDP 
DRYGTTVPYT SRRPKDSERE GQGYSFVSRG EMEADVRAGR YLEHGEYEGN LYGTRIDSIR 
GVVAAGKVCV LDVNPQAVKV LRTAEFVPYV VFIEAPDFET LRAMNRAALE SGISTKQLTE 
ADLRRTVEES SRIQRGYGHY FDLCLVNSNL ERTFRELQTA MEKLRTEPQW VPVSWVY

Genular Protein ID: 3113166306

Symbol: A0A0A0MRU0_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0A0MRU0

Database IDs:

ARBA 2 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 2 ExpressionAtlas 1 Gene3D 4 GeneTree 1 HGNC 1 InterPro 13 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 9 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 4 Proteomes 2 ProteomicsDB 1 RefSeq 1 SMART 4 SMR 1 SUPFAM 4 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

Sequence Information:

  • Length: 569
  • Mass: 63320
  • Checksum: 43F8CAE46DFEC38D
  • Sequence:
    • MAGSPGSGVS LEGISLESSE EAELQREAMQ QVLDNLGSLP SATGAAELDL IFLRGIMESP 
IVRSLAKAHE RLEETKLEAV RDNNLELVQE ILRDLAQLAE QSSTAAELAH ILQEPHFQSL 
LETHDSVASK TYETPPPSPG LDPTFSNQPV PPDAVRMVGI RKTAGEHLGV TFRVEGGELV 
IARILHGGMV AQQGLLHVGD IIKEVNGQPV GSDPRALQEL LRNASGSVIL KILPSYQEPH 
LPRQVFVKCH FDYDPARDSL IPCKEAGLRF NAGDLLQIVN QDDANWWQAC HVEGGSAGLI 
PSQLLEEKRK AFVKRDLELT PNSGTLCGSL SGKKKKRMMY LTTKNAEFDR HELLIYEEVA 
RMPPFRRKTL VLIGAQGVGR RSLKNKLIMW DPDRYGTTVP YTSRRPKDSE REGQGYSFVS 
RGEMEADVRA GRYLEHGEYE GNLYGTRIDS IRGVVAAGKV CVLDVNPQAV KVLRTAEFVP 
YVVFIEAPDF ETLRAMNRAA LESGISTKQL TEADLRRTVE ESSRIQRGYG HYFDLCLVNS 
NLERTFRELQ TAMEKLRTEP QWVPVSWVY

Genular Protein ID: 1094223994

Symbol: D3DX48_HUMAN

Name: N/A

UniProtKB Accession Codes:

D3DX48

Database IDs:

ARBA 2 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 5 Ensembl 3 GO 10 Gene3D 4 GeneTree 1 HGNC 1 InterPro 13 MANE-Select 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 9 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 4 Proteomes 2 ProteomicsDB 1 RefSeq 2 SMART 4 SUPFAM 4 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

Sequence Information:

  • Length: 552
  • Mass: 61590
  • Checksum: 82BD206CB55A8088
  • Sequence:
    • MPVAATNSET AMQQVLDNLG SLPSATGAAE LDLIFLRGIM ESPIVRSLAK AHERLEETKL 
EAVRDNNLEL VQEILRDLAQ LAEQSSTAAE LAHILQEPHF QSLLETHDSV ASKTYETPPP 
SPGLDPTFSN QPVPPDAVRM VGIRKTAGEH LGVTFRVEGG ELVIARILHG GMVAQQGLLH 
VGDIIKEVNG QPVGSDPRAL QELLRNASGS VILKILPSYQ EPHLPRQVFV KCHFDYDPAR 
DSLIPCKEAG LRFNAGDLLQ IVNQDDANWW QACHVEGGSA GLIPSQLLEE KRKAFVKRDL 
ELTPNSGTLC GSLSGKKKKR MMYLTTKNAE FDRHELLIYE EVARMPPFRR KTLVLIGAQG 
VGRRSLKNKL IMWDPDRYGT TVPYTSRRPK DSEREGQGYS FVSRGEMEAD VRAGRYLEHG 
EYEGNLYGTR IDSIRGVVAA GKVCVLDVNP QAVKVLRTAE FVPYVVFIEA PDFETLRAMN 
RAALESGIST KQLTEADLRR TVEESSRIQR GYGHYFDLCL VNSNLERTFR ELQTAMEKLR 
TEPQWVPVSW VY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.