Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 48.9270
Cell Significance Index: -12.4100 - Cell Name: precursor cell (CL0011115)
Fold Change: 11.2165
Cell Significance Index: 85.0600 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 6.4068
Cell Significance Index: 290.4000 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 5.6216
Cell Significance Index: 121.7900 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 5.6069
Cell Significance Index: -15.0200 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 2.0637
Cell Significance Index: 224.4700 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: 2.0200
Cell Significance Index: 30.4400 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 1.9430
Cell Significance Index: 41.3800 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 1.9311
Cell Significance Index: 28.9400 - Cell Name: large intestine goblet cell (CL1000320)
Fold Change: 1.7827
Cell Significance Index: 19.3200 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 1.0544
Cell Significance Index: 63.3000 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.9438
Cell Significance Index: 852.1800 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.9191
Cell Significance Index: 32.3000 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.8442
Cell Significance Index: 27.0400 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.8146
Cell Significance Index: 132.4800 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.6837
Cell Significance Index: 17.0900 - Cell Name: helper T cell (CL0000912)
Fold Change: 0.6425
Cell Significance Index: 9.1300 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 0.6173
Cell Significance Index: 12.8100 - Cell Name: tuft cell of small intestine (CL0009080)
Fold Change: 0.5789
Cell Significance Index: 5.8400 - Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: 0.3290
Cell Significance Index: 2.1500 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.2338
Cell Significance Index: 2.4200 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2240
Cell Significance Index: 42.6200 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.1945
Cell Significance Index: 19.2400 - Cell Name: colonocyte (CL1000347)
Fold Change: 0.1545
Cell Significance Index: 0.9600 - Cell Name: urothelial cell (CL0000731)
Fold Change: 0.1183
Cell Significance Index: 0.8300 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.0276
Cell Significance Index: 0.8000 - Cell Name: stem cell (CL0000034)
Fold Change: 0.0014
Cell Significance Index: 0.0100 - Cell Name: enterocyte (CL0000584)
Fold Change: -0.0016
Cell Significance Index: -0.0100 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: -0.0016
Cell Significance Index: -1.1400 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0018
Cell Significance Index: -0.7900 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.0037
Cell Significance Index: -0.1600 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0061
Cell Significance Index: -11.5000 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0098
Cell Significance Index: -7.2800 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0100
Cell Significance Index: -0.5100 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.0144
Cell Significance Index: -1.0000 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.0155
Cell Significance Index: -1.1000 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0158
Cell Significance Index: -11.9700 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.0160
Cell Significance Index: -0.6500 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0171
Cell Significance Index: -9.6500 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0176
Cell Significance Index: -11.1900 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0178
Cell Significance Index: -32.8700 - Cell Name: L4 intratelencephalic projecting glutamatergic neuron (CL4030063)
Fold Change: -0.0182
Cell Significance Index: -0.2000 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0211
Cell Significance Index: -32.5100 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0218
Cell Significance Index: -11.8800 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0242
Cell Significance Index: -32.8700 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0244
Cell Significance Index: -4.8400 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0253
Cell Significance Index: -0.7100 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0270
Cell Significance Index: -9.6900 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0277
Cell Significance Index: -4.9900 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: -0.0305
Cell Significance Index: -0.2900 - Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
Fold Change: -0.0336
Cell Significance Index: -0.5800 - Cell Name: mucous neck cell (CL0000651)
Fold Change: -0.0357
Cell Significance Index: -0.1700 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0369
Cell Significance Index: -4.3000 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.0370
Cell Significance Index: -0.9500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0387
Cell Significance Index: -17.5800 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0440
Cell Significance Index: -5.0400 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0474
Cell Significance Index: -2.2100 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.0479
Cell Significance Index: -0.8200 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0480
Cell Significance Index: -10.1200 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.0506
Cell Significance Index: -1.0600 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0539
Cell Significance Index: -15.5200 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0548
Cell Significance Index: -11.0000 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0593
Cell Significance Index: -10.1300 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0630
Cell Significance Index: -7.7500 - Cell Name: CD141-positive myeloid dendritic cell (CL0002394)
Fold Change: -0.0657
Cell Significance Index: -0.7100 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.0713
Cell Significance Index: -1.9400 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0736
Cell Significance Index: -10.7000 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: -0.0814
Cell Significance Index: -0.8200 - Cell Name: L5/6 near-projecting glutamatergic neuron (CL4030067)
Fold Change: -0.0821
Cell Significance Index: -0.4300 - Cell Name: stromal cell of endometrium (CL0002255)
Fold Change: -0.0851
Cell Significance Index: -1.2100 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0879
Cell Significance Index: -12.0700 - Cell Name: myoepithelial cell (CL0000185)
Fold Change: -0.0899
Cell Significance Index: -1.0200 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.0910
Cell Significance Index: -5.5800 - Cell Name: immature NK T cell (CL0000914)
Fold Change: -0.0945
Cell Significance Index: -1.2100 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: -0.0957
Cell Significance Index: -1.0400 - Cell Name: osteoblast (CL0000062)
Fold Change: -0.1072
Cell Significance Index: -1.0400 - Cell Name: epithelial cell of urethra (CL1000296)
Fold Change: -0.1131
Cell Significance Index: -0.7000 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.1153
Cell Significance Index: -2.2500 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1198
Cell Significance Index: -12.2400 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1231
Cell Significance Index: -12.8200 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: -0.1457
Cell Significance Index: -0.9900 - Cell Name: parietal cell (CL0000162)
Fold Change: -0.1491
Cell Significance Index: -1.4100 - Cell Name: epithelial cell of esophagus (CL0002252)
Fold Change: -0.1657
Cell Significance Index: -1.1000 - Cell Name: glandular cell of esophagus (CL0002657)
Fold Change: -0.1671
Cell Significance Index: -1.7900 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.1770
Cell Significance Index: -11.9000 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.1858
Cell Significance Index: -9.6800 - Cell Name: pulmonary capillary endothelial cell (CL4028001)
Fold Change: -0.1877
Cell Significance Index: -2.5700 - Cell Name: intrahepatic cholangiocyte (CL0002538)
Fold Change: -0.1898
Cell Significance Index: -0.7200 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.1975
Cell Significance Index: -12.7400 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: -0.2082
Cell Significance Index: -2.1600 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.2156
Cell Significance Index: -13.2500 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: -0.2246
Cell Significance Index: -2.6000 - Cell Name: natural T-regulatory cell (CL0000903)
Fold Change: -0.2308
Cell Significance Index: -2.2600 - Cell Name: embryonic fibroblast (CL2000042)
Fold Change: -0.2425
Cell Significance Index: -1.1600 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.2506
Cell Significance Index: -19.2300 - Cell Name: skin fibroblast (CL0002620)
Fold Change: -0.2556
Cell Significance Index: -0.5900 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.2609
Cell Significance Index: -11.5400 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.2723
Cell Significance Index: -32.1100 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: -0.2787
Cell Significance Index: -2.9100 - Cell Name: epithelial cell (CL0000066)
Fold Change: -0.2920
Cell Significance Index: -3.0800
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3498526183
Symbol: MYO1A_HUMAN
Name: Unconventional myosin-Ia
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10653589
Title: Brush border myosin I (BBMI): a basally localized transcript in human jejunal enterocytes.
PubMed ID: 10653589
PubMed ID: 9858156
Title: Human brush border myosin-I and myosin-Ic expression in human intestine and Caco-2BBe cells.
PubMed ID: 9858156
DOI: 10.1002/(sici)1097-0169(1998)41:4<308::aid-cm4>3.0.co;2-j
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 15883161
Title: Alpha-kinase 1, a new component in apical protein transport.
PubMed ID: 15883161
PubMed ID: 12736868
Title: Multiple mutations of MYO1A, a cochlear-expressed gene, in sensorineural hearing loss.
PubMed ID: 12736868
DOI: 10.1086/375654
PubMed ID: 24616153
Title: Targeted and genomewide NGS data disqualify mutations in MYO1A, the 'DFNA48 gene', as a cause of deafness.
PubMed ID: 24616153
DOI: 10.1002/humu.22532
Sequence Information:
- Length: 1043
- Mass: 118401
- Checksum: EE5D79D9D6E085DC
- Sequence:
MPLLEGSVGV EDLVLLEPLV EESLLKNLQL RYENKEIYTY IGNVVISVNP YQQLPIYGPE FIAKYQDYTF YELKPHIYAL ANVAYQSLRD RDRDQCILIT GESGSGKTEA SKLVMSYVAA VCGKGEQVNS VKEQLLQSNP VLEAFGNAKT IRNNNSSRFG KYMDIEFDFK GSPLGGVITN YLLEKSRLVK QLKGERNFHI FYQLLAGADE QLLKALKLER DTTGYAYLNH EVSRVDGMDD ASSFRAVQSA MAVIGFSEEE IRQVLEVTSM VLKLGNVLVA DEFQASGIPA SGIRDGRGVR EIGEMVGLNS EEVERALCSR TMETAKEKVV TALNVMQAQY ARDALAKNIY SRLFDWIVNR INESIKVGIG EKKKVMGVLD IYGFEILEDN SFEQFVINYC NEKLQQVFIE MTLKEEQEEY KREGIPWTKV DYFDNGIICK LIEHNQRGIL AMLDEECLRP GVVSDSTFLA KLNQLFSKHG HYESKVTQNA QRQYDHTMGL SCFRICHYAG KVTYNVTSFI DKNNDLLFRD LLQAMWKAQH PLLRSLFPEG NPKQASLKRP PTAGAQFKSS VAILMKNLYS KSPNYIRCIK PNEHQQRGQF SSDLVATQAR YLGLLENVRV RRAGYAHRQG YGPFLERYRL LSRSTWPHWN GGDREGVEKV LGELSMSSGE LAFGKTKIFI RSPKTLFYLE EQRRLRLQQL ATLIQKIYRG WRCRTHYQLM RKSQILISSW FRGNMQKKCY GKIKASVLLI QAFVRGWKAR KNYRKYFRSE AALTLADFIY KSMVQKFLLG LKNNLPSTNV LDKTWPAAPY KCLSTANQEL QQLFYQWKCK RFRDQLSPKQ VEILREKLCA SELFKGKKAS YPQSVPIPFC GDYIGLQGNP KLQKLKGGEE GPVLMAEAVK KVNRGNGKTS SRILLLTKGH VILTDTKKSQ AKIVIGLDNV AGVSVTSLKD GLFSLHLSEM SSVGSKGDFL LVSEHVIELL TKMYRAVLDA TQRQLTVTVT EKFSVRFKEN SVAVKVVQGP AGGDNSKLRY KKKGSHCLEV TVQ
Genular Protein ID: 3312136376
Symbol: B2R643_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 1043
- Mass: 118415
- Checksum: DE3AB8A030AAF671
- Sequence:
MPLLEGSVGV EDLVLLEPLV EESLLKNLQL RYENKEIYTY IGNVVISVNP YQQLPIYGPE FIAKYQDYTF YELKPHIYAL ANVAYQSLRD RDRDQCILIT GESGSGKTEA SKLVMSYVAA VCGKGEQVNS VKEQLLQSNP VLEAFGNAKT IRNNNSSRFG KYMDIEFDFK GSPLGGVITN YLLEKSRLVK QLKGERNFHI FYQLLAGADE QLLKALKLER DTTGYAYLNH EVSRLDGMDD ASSFRAVQSA MAVIGFSEEE IRQVLEVTSM VLKLGNVLVA DEFQASGIPA SGIRDGRGVR EIGEMVGLNS EEVERALCSR TMETAKEKVV TALNVMQAQY ARDALAKNIY SRLFDWIVNR INESIKVGIG EKKKVMGVLD IYGFEILEDN SFEQFVINYC NEKLQQVFIE MTLKEEQEEY KREGIPWTKV DYFDNGIICK LIEHNQRGIL AMLDEECLRP GVVSDSTFLA KLNQLFSKHG HYESKVTQNA QRQYDHTMGL SCFRICHYAG KVTYNVTSFI DKNNDLLFRD LLQAMWKAQH PLLRSLFPEG NPKQASLKRP PTAGAQFKSS VAILMKNLYS KSPNYIRCIK PNEHQQRGQF SSDLVATQAR YLGLLENVRV RRAGYAHRQG YGPFLERYRL LSRSTWPHWN GGDREGVEKV LGELSMSSGE LAFGKTKIFI RSPKTLFYLE EQRRLRLQQL ATLIQKIYRG WRCRTHYQLM RKSQILISSW FRGNMQKKCY GKIKASVLLI QAFVRGWKAR KNYRKYFRSE AALTLADFIY KSMVQKFLLG LKNNLPSTNV LDKTWPAAPY KCLSTANQEL QQLFYQWKCK RFRDQLSPKQ VEILREKLCA SELFKGKKAS YPQSVPIPFC GDYIGLQGNP KLQKLKGGEE GPVLMAEAVK KVNRGNGKTS SRILLLTKGH VILTDTKKSQ AKIVIGLDNV AGVSVTSLKD GLFSLHLSEM SSVGSKGDFL LVSEHVIELL TKMYRAVLDA TQRQLTVTVT EKFSVRFKEN SVAVKVVQGP AGGDNSKLRY KKKGSHCLEV TVQ
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.