Details for: NPR3

Gene ID: 4883

Symbol: NPR3

Ensembl ID: ENSG00000113389

Description: natriuretic peptide receptor 3

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 78.0480
    Cell Significance Index: -12.1400
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 27.1257
    Cell Significance Index: -11.0200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 10.4870
    Cell Significance Index: -12.9300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 5.9943
    Cell Significance Index: 160.6200
  • Cell Name: endocardial cell (CL0002350)
    Fold Change: 3.8202
    Cell Significance Index: 22.5600
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 3.3274
    Cell Significance Index: -13.1300
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 1.5944
    Cell Significance Index: 8.3900
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 1.2770
    Cell Significance Index: 26.7300
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 0.3603
    Cell Significance Index: 5.4300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.3306
    Cell Significance Index: 25.3700
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: 0.3239
    Cell Significance Index: 2.1500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.2494
    Cell Significance Index: 383.9700
  • Cell Name: helper T cell (CL0000912)
    Fold Change: 0.2407
    Cell Significance Index: 3.4200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.2221
    Cell Significance Index: 409.6500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.2144
    Cell Significance Index: 11.1700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.2024
    Cell Significance Index: 5.6600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1819
    Cell Significance Index: 65.2600
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.1545
    Cell Significance Index: 2.3900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.0774
    Cell Significance Index: 12.5900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0645
    Cell Significance Index: 12.2800
  • Cell Name: early promyelocyte (CL0002154)
    Fold Change: 0.0525
    Cell Significance Index: 0.3400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 0.0519
    Cell Significance Index: 32.3900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0437
    Cell Significance Index: 32.0100
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0348
    Cell Significance Index: 24.0500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: 0.0347
    Cell Significance Index: 2.7500
  • Cell Name: alveolar capillary type 1 endothelial cell (CL4028002)
    Fold Change: 0.0248
    Cell Significance Index: 0.1800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0141
    Cell Significance Index: 26.5100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0118
    Cell Significance Index: 0.2600
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 0.0052
    Cell Significance Index: 0.0400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0042
    Cell Significance Index: 5.7000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0039
    Cell Significance Index: 0.5300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0034
    Cell Significance Index: 0.6700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.0029
    Cell Significance Index: 0.0800
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: 0.0024
    Cell Significance Index: 0.0300
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: -0.0009
    Cell Significance Index: -0.0100
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.0012
    Cell Significance Index: -0.0200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0068
    Cell Significance Index: -5.0600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0073
    Cell Significance Index: -4.1200
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0137
    Cell Significance Index: -6.0400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0141
    Cell Significance Index: -0.3700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0146
    Cell Significance Index: -7.9900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0161
    Cell Significance Index: -3.4000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0171
    Cell Significance Index: -12.9300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0179
    Cell Significance Index: -11.4000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0206
    Cell Significance Index: -2.1000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0273
    Cell Significance Index: -12.4000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0285
    Cell Significance Index: -5.7100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0330
    Cell Significance Index: -9.5000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0374
    Cell Significance Index: -4.8000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0404
    Cell Significance Index: -6.9000
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.0485
    Cell Significance Index: -2.9100
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.0485
    Cell Significance Index: -0.4000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0527
    Cell Significance Index: -9.5000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0537
    Cell Significance Index: -7.8000
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0753
    Cell Significance Index: -1.2600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0788
    Cell Significance Index: -9.1800
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.0792
    Cell Significance Index: -1.0000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0794
    Cell Significance Index: -4.1700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0797
    Cell Significance Index: -9.8000
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0817
    Cell Significance Index: -1.6400
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.0884
    Cell Significance Index: -10.0900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0913
    Cell Significance Index: -9.5100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: -0.0940
    Cell Significance Index: -9.3000
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.0979
    Cell Significance Index: -10.6500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1045
    Cell Significance Index: -13.5000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1074
    Cell Significance Index: -12.3000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1123
    Cell Significance Index: -6.9100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.1168
    Cell Significance Index: -8.0800
  • Cell Name: megakaryocyte progenitor cell (CL0000553)
    Fold Change: -0.1189
    Cell Significance Index: -0.8600
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.1329
    Cell Significance Index: -3.5600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1355
    Cell Significance Index: -4.3400
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.1385
    Cell Significance Index: -3.2000
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.1423
    Cell Significance Index: -0.8600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1461
    Cell Significance Index: -9.2100
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.1470
    Cell Significance Index: -2.1700
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.1479
    Cell Significance Index: -6.4300
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.1716
    Cell Significance Index: -4.4100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1818
    Cell Significance Index: -13.5500
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -0.1903
    Cell Significance Index: -2.4400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1910
    Cell Significance Index: -10.7200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1910
    Cell Significance Index: -12.8400
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: -0.1930
    Cell Significance Index: -2.4300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1958
    Cell Significance Index: -12.6300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.2022
    Cell Significance Index: -9.1700
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.2216
    Cell Significance Index: -4.7200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.2336
    Cell Significance Index: -6.7300
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.2425
    Cell Significance Index: -5.0300
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.2434
    Cell Significance Index: -4.7500
  • Cell Name: epidermal cell (CL0000362)
    Fold Change: -0.2440
    Cell Significance Index: -0.5500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.2542
    Cell Significance Index: -11.8500
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.2582
    Cell Significance Index: -6.1900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.2647
    Cell Significance Index: -13.7500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.2692
    Cell Significance Index: -12.6500
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2847
    Cell Significance Index: -9.3200
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: -0.2868
    Cell Significance Index: -2.5900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2883
    Cell Significance Index: -12.7500
  • Cell Name: flat midget bipolar cell (CL4033033)
    Fold Change: -0.2916
    Cell Significance Index: -3.6300
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.3062
    Cell Significance Index: -11.2400
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.3096
    Cell Significance Index: -7.9100
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.3104
    Cell Significance Index: -4.4500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **G-protein coupled receptor activity**: NPR3 belongs to the G-protein coupled receptor family, which is characterized by its ability to activate G-proteins upon ligand binding, leading to various downstream signaling pathways. 2. **Natriuretic peptide receptor activity**: NPR3 specifically recognizes and binds to natriuretic peptides, such as ANP and BNP, which are key regulators of cardiovascular function and electrolyte balance. 3. **Regulation of blood pressure**: NPR3 plays a crucial role in regulating blood pressure by mediating the effects of natriuretic peptides, which promote vasodilation and natriuresis. 4. **Osteoclast proliferation**: NPR3 is also involved in regulating osteoclast proliferation, which is essential for bone remodeling and calcium homeostasis. **Pathways and Functions:** 1. **Natriuretic peptide signaling pathway**: NPR3 mediates the effects of ANP and BNP by activating G-proteins, which leads to the activation of downstream signaling pathways, including: * **Phospholipase C (PLC) pathway**: NPR3 activates PLC, which generates inositol trisphosphate (IP3) and diacylglycerol (DAG), leading to calcium mobilization and protein kinase C activation. * **Protein kinase A (PKA) pathway**: NPR3 activates PKA, which phosphorylates and activates downstream targets, including ion channels and transcription factors. 2. **Angiogenesis**: NPR3 regulates angiogenesis by modulating the expression of pro- and anti-angiogenic factors, such as vascular endothelial growth factor (VEGF) and angiopoietin-1. 3. **Osteoclast proliferation**: NPR3 regulates osteoclast proliferation by modulating the expression of osteoclastogenic factors, such as RANKL and osteoprotegerin. **Clinical Significance:** 1. **Hypertension**: NPR3 dysregulation has been implicated in the pathogenesis of hypertension, a major cardiovascular disease. 2. **Osteoporosis**: NPR3 dysregulation has been linked to osteoporosis, a condition characterized by decreased bone mass and increased risk of fractures. 3. **Cardiovascular disease**: NPR3 plays a crucial role in regulating cardiovascular function, and its dysregulation has been implicated in various cardiovascular diseases, including heart failure and coronary artery disease. 4. **Cancer**: NPR3 has been implicated in cancer progression, including metastasis and angiogenesis. In conclusion, NPR3 is a key player in regulating blood pressure and osteoclast proliferation, and its dysregulation has been implicated in various cardiovascular and bone disorders. Further research is needed to fully elucidate the mechanisms of NPR3 in these diseases and to explore its potential as a therapeutic target.

Genular Protein ID: 1827804603

Symbol: ANPRC_HUMAN

Name: Atrial natriuretic peptide receptor 3

UniProtKB Accession Codes:

P17342 A2RRD1 B4DT84 E7EPG9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 2 CTD 1 ChEBI 3 ChEMBL 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 EMBL 8 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 21 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 4 PIR 1 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 RefSeq 3 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2162522

Title: cDNA sequence of the human atrial natriuretic peptide clearance receptor.

PubMed ID: 2162522

DOI: 10.1093/nar/18.11.3412

PubMed ID: 2169733

Title: Isolation and functional expression of the human atrial natriuretic peptide clearance receptor cDNA.

PubMed ID: 2169733

DOI: 10.1016/0006-291x(90)91216-f

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7727388

Title: The disulfide linkages and glycosylation sites of the human natriuretic peptide receptor-C homodimer.

PubMed ID: 7727388

DOI: 10.1021/bi00203a036

PubMed ID: 1660465

Title: Extracellular domain-IgG fusion proteins for three human natriuretic peptide receptors. Hormone pharmacology and application to solid phase screening of synthetic peptide antisera.

PubMed ID: 1660465

DOI: 10.1016/s0021-9258(18)54463-x

PubMed ID: 11533490

Title: Allosteric activation of a spring-loaded natriuretic peptide receptor dimer by hormone.

PubMed ID: 11533490

DOI: 10.1126/science.1062246

PubMed ID: 16870210

Title: Structural determinants of natriuretic peptide receptor specificity and degeneracy.

PubMed ID: 16870210

DOI: 10.1016/j.jmb.2006.06.060

PubMed ID: 30032985

Title: Bi-allelic Loss-of-Function Mutations in the NPR-C Receptor Result in Enhanced Growth and Connective Tissue Abnormalities.

PubMed ID: 30032985

DOI: 10.1016/j.ajhg.2018.06.007

Sequence Information:

  • Length: 541
  • Mass: 59808
  • Checksum: 8A66415F7F7D62B7
  • Sequence:
    • MPSLLVLTFS PCVLLGWALL AGGTGGGGVG GGGGGAGIGG GRQEREALPP QKIEVLVLLP 
QDDSYLFSLT RVRPAIEYAL RSVEGNGTGR RLLPPGTRFQ VAYEDSDCGN RALFSLVDRV 
AAARGAKPDL ILGPVCEYAA APVARLASHW DLPMLSAGAL AAGFQHKDSE YSHLTRVAPA 
YAKMGEMMLA LFRHHHWSRA ALVYSDDKLE RNCYFTLEGV HEVFQEEGLH TSIYSFDETK 
DLDLEDIVRN IQASERVVIM CASSDTIRSI MLVAHRHGMT SGDYAFFNIE LFNSSSYGDG 
SWKRGDKHDF EAKQAYSSLQ TVTLLRTVKP EFEKFSMEVK SSVEKQGLNM EDYVNMFVEG 
FHDAILLYVL ALHEVLRAGY SKKDGGKIIQ QTWNRTFEGI AGQVSIDANG DRYGDFSVIA 
MTDVEAGTQE VIGDYFGKEG RFEMRPNVKY PWGPLKLRID ENRIVEHTNS SPCKSSGGLE 
ESAVTGIVVG ALLGAGLLMA FYFFRKKYRI TIERRTQQEE SNLGKHRELR EDSIRSHFSV 
A

Genular Protein ID: 3384452133

Symbol: Q60I31_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q60I31

Database IDs:

ARBA 5 AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 DisGeNET 1 EMBL 4 ExpressionAtlas 1 GO 4 Gene3D 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 1 Pfam 2 PharmGKB 1 RefSeq 1 SAM 2 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

Sequence Information:

  • Length: 540
  • Mass: 59767
  • Checksum: 53EE0020A296D6F5
  • Sequence:
    • MPSLLVLTFS PCVLLGWALL AGGTGGGGVG GGGGGAGIGG GRQEREALPP QKIEVLVLLP 
QDDSYLFSLT RVRPAIEYAL RSVEGNGTGR RLLPPGTRFQ VAYEDSDCGN RALFSLVDRV 
AAARGAKPDL ILGPVCEYAA APVARLASHW DLPMLSAGAL AAGFQHKDSE YSHLTRVAPA 
YAKMGEMMLA LFRHHHWSRA ALVYSDDKLE RNCYFTLEGV HEVFQEEGLH TSIYSFDETK 
DLDLEDIVRN IQASERVVIM CASSDTIRSI MLVAHRHGMT SGDYAFFNIE LFNSSSYGDG 
SWKRGDKHDF EAKQAYSSLQ TVTLLRTVKP EFEKFSMEVK SSVEKQGLNM EDYVNMFVEG 
FHDAILLYVL ALHEVLRAGY SKKDGGKIIQ QTWNRTFEGI AGQVSIDANG DRYGDFSVIA 
MTDVEAGTQE VIGDYFGKEG RFEMRPNVKY PWGPLKLRID ENRIVEHTNS SPCKSCGLEE 
SAVTGIVVGA LLGAGLLMAF YFFRKKYRIT IERRTQQEES NLGKHRELRE DSIRSHFSVA

Genular Protein ID: 1004909990

Symbol: A8K4A5_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K4A5

Database IDs:

ARBA 5 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 1 PeptideAtlas 1 Pfam 2 RefSeq 1 SAM 2 SUPFAM 1

Sequence Information:

  • Length: 541
  • Mass: 59809
  • Checksum: 8A664152121D62B7
  • Sequence:
    • MPSLLVLTFS PCVLLGWALL AGGTGGGGVG GGGGGAGIGG GRQEREALPP QKIEVLVLLP 
QDDSYLFSLT RVRPAIEYAL RSVEGNGTGR RLLPPGTRFQ VAYEDSDCGN RALFSLVDRV 
AAARGAKPDL ILGPVCEYAA APVARLASHW DLPMLSAGAL AAGFQHKDSE YSHLTRVAPA 
YAKMGEMMLA LFRHHHWSRA ALVYSDDKLE RNCYFTLEGV HEVFQEEGLH TSIYSFDETK 
DLDLEDIVRN IQASERVVIM CASSDTIRSI MLVAHRHGMT SGDYAFFNIE LFNSSSYGDG 
SWKRGDKHDF EAKQAYSSLQ TVTLLRTVKP EFEKFSMEVK SSVEKQGLNM EDYVNMFVEG 
FHDAILLYVL ALHEVLRAGY SKKDGGKIIQ QTWNRTFEGI AGQVSIDANG DRYGDFSVIA 
MTDVEAGTQE VIGDYFGKEG RFEMRPNVKY PWGPLKLRID ENRIVEHTNS SPCKSSGGLE 
ESAVTGIVVG ALLGAGLLMA FYFFRKKYRI TIERRTQQEE SDLGKHRELR EDSIRSHFSV 
A

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.