Details for: OPRK1

Gene ID: 4986

Symbol: OPRK1

Ensembl ID: ENSG00000082556

Description: opioid receptor kappa 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 5.9272
    Cell Significance Index: 122.9600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 4.5807
    Cell Significance Index: 160.9600
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 3.1021
    Cell Significance Index: 77.5500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 2.7671
    Cell Significance Index: 88.6300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 2.5530
    Cell Significance Index: 55.3100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 1.8704
    Cell Significance Index: 114.6700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.7370
    Cell Significance Index: 140.2500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.7190
    Cell Significance Index: 32.5900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.4639
    Cell Significance Index: 166.4000
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.4038
    Cell Significance Index: 24.2400
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: 0.3418
    Cell Significance Index: 4.5600
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.2800
    Cell Significance Index: 30.4600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2598
    Cell Significance Index: 25.7000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.2545
    Cell Significance Index: 5.4200
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.2398
    Cell Significance Index: 216.5600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.2075
    Cell Significance Index: 9.1800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.1587
    Cell Significance Index: 25.8200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.1532
    Cell Significance Index: 30.7400
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1231
    Cell Significance Index: 8.5200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.0763
    Cell Significance Index: 2.8900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.0555
    Cell Significance Index: 3.7300
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.0506
    Cell Significance Index: 1.3000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0410
    Cell Significance Index: 28.3600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0218
    Cell Significance Index: 2.8000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0101
    Cell Significance Index: 0.2900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0018
    Cell Significance Index: 0.9900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0003
    Cell Significance Index: 0.1200
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0024
    Cell Significance Index: -0.1000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0031
    Cell Significance Index: -4.2300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0036
    Cell Significance Index: -6.7900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0046
    Cell Significance Index: -8.4800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0056
    Cell Significance Index: -8.5500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0096
    Cell Significance Index: -2.7500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0118
    Cell Significance Index: -8.7100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0144
    Cell Significance Index: -8.1300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0146
    Cell Significance Index: -9.2900
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0149
    Cell Significance Index: -0.3000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0192
    Cell Significance Index: -8.7100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0197
    Cell Significance Index: -2.3000
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.0349
    Cell Significance Index: -0.8700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0387
    Cell Significance Index: -7.6800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0445
    Cell Significance Index: -5.1000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0448
    Cell Significance Index: -9.4400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0459
    Cell Significance Index: -8.2800
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.0474
    Cell Significance Index: -0.7200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0541
    Cell Significance Index: -7.4300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0554
    Cell Significance Index: -9.4600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0603
    Cell Significance Index: -8.7700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0668
    Cell Significance Index: -1.8700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0695
    Cell Significance Index: -8.5500
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0747
    Cell Significance Index: -1.0700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0847
    Cell Significance Index: -8.8200
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0921
    Cell Significance Index: -1.9900
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.0944
    Cell Significance Index: -1.4600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1075
    Cell Significance Index: -6.6100
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.1143
    Cell Significance Index: -2.2600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1174
    Cell Significance Index: -9.0100
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.1192
    Cell Significance Index: -1.1300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1366
    Cell Significance Index: -7.6700
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.1419
    Cell Significance Index: -2.9700
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1456
    Cell Significance Index: -9.4000
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: -0.1681
    Cell Significance Index: -2.1800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1764
    Cell Significance Index: -8.2300
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.1814
    Cell Significance Index: -4.3500
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.1933
    Cell Significance Index: -3.7800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1952
    Cell Significance Index: -10.2500
  • Cell Name: professional antigen presenting cell (CL0000145)
    Fold Change: -0.1958
    Cell Significance Index: -1.7700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.1989
    Cell Significance Index: -5.3100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.2020
    Cell Significance Index: -9.5000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2034
    Cell Significance Index: -6.6600
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.2042
    Cell Significance Index: -4.0200
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.2044
    Cell Significance Index: -3.0800
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: -0.2068
    Cell Significance Index: -2.1400
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2081
    Cell Significance Index: -7.2900
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.2128
    Cell Significance Index: -1.4400
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: -0.2134
    Cell Significance Index: -3.1100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.2185
    Cell Significance Index: -11.3500
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.2250
    Cell Significance Index: -6.4200
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.2357
    Cell Significance Index: -11.9100
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.2384
    Cell Significance Index: -7.5400
  • Cell Name: pulmonary capillary endothelial cell (CL4028001)
    Fold Change: -0.2425
    Cell Significance Index: -3.3200
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2468
    Cell Significance Index: -7.8600
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.2469
    Cell Significance Index: -6.7200
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.2507
    Cell Significance Index: -5.0000
  • Cell Name: tendon cell (CL0000388)
    Fold Change: -0.2508
    Cell Significance Index: -3.4100
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.2601
    Cell Significance Index: -5.5200
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.2743
    Cell Significance Index: -4.7000
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.2803
    Cell Significance Index: -9.7400
  • Cell Name: retinal astrocyte (CL4033015)
    Fold Change: -0.2810
    Cell Significance Index: -2.7500
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.2853
    Cell Significance Index: -6.9600
  • Cell Name: L5/6 near-projecting glutamatergic neuron (CL4030067)
    Fold Change: -0.2960
    Cell Significance Index: -1.5500
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.2971
    Cell Significance Index: -7.4200
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.2979
    Cell Significance Index: -7.4300
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.3091
    Cell Significance Index: -9.1100
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.3118
    Cell Significance Index: -3.3900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.3164
    Cell Significance Index: -8.3200
  • Cell Name: osteoblast (CL0000062)
    Fold Change: -0.3185
    Cell Significance Index: -3.0900
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.3202
    Cell Significance Index: -5.5200
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: -0.3295
    Cell Significance Index: -5.4300
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: -0.3309
    Cell Significance Index: -3.1900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Structure:** The KOR is a transmembrane receptor with seven transmembrane domains, similar to other G-protein coupled receptors. 2. **Activation:** The receptor is activated by endogenous opioids, such as dynorphin, and exogenous opioids, like morphine. 3. **Signaling:** Activation of the KOR triggers a cascade of downstream signaling events, including the inhibition of adenylate cyclase, which leads to the suppression of cAMP production and subsequent modulation of various cellular processes. 4. **Expression:** The OPRK1 gene is widely expressed in various tissues, including the brain, immune cells, and the gastrointestinal tract. 5. **Regulation:** The KOR is negatively regulated by several mechanisms, including desensitization, internalization, and phosphorylation. **Pathways and Functions:** 1. **Pain Modulation:** The KOR plays a crucial role in modulating pain perception, particularly in the context of chronic pain and opioid tolerance. 2. **Immune Response:** The receptor is involved in regulating immune responses, including the production of cytokines and the activation of immune cells. 3. **Mood Regulation:** The KOR is implicated in modulating mood and stress responses, particularly in the context of depression and anxiety disorders. 4. **Gastrointestinal Function:** The receptor is expressed in the gastrointestinal tract and plays a role in regulating gut motility and secretion. 5. **Neurotransmission:** The KOR is involved in regulating neurotransmission, particularly in the context of dopamine and serotonin signaling. **Clinical Significance:** 1. **Pain Management:** The KOR has been explored as a potential therapeutic target for the treatment of chronic pain, particularly in the context of opioid addiction and tolerance. 2. **Addiction:** The receptor is implicated in the development and maintenance of opioid addiction, and its modulation may provide a novel therapeutic approach for treating addiction. 3. **Autoimmune Disorders:** The KOR has been shown to play a role in regulating immune responses, and its modulation may provide a novel therapeutic approach for treating autoimmune disorders, such as multiple sclerosis and rheumatoid arthritis. 4. **Cancer:** The receptor is expressed in various types of cancer, including lung, breast, and colon cancer, and its modulation may provide a novel therapeutic approach for treating cancer. 5. **Neurological Disorders:** The KOR is implicated in the development and maintenance of various neurological disorders, including Parkinson's disease, Alzheimer's disease, and Huntington's disease. In conclusion, the OPRK1 gene and its encoded receptor, the kappa-type opioid receptor, play a complex and multifaceted role in modulating various physiological processes, including pain perception, mood regulation, and immune response. Further research is needed to fully understand the implications of OPRK1 in human physiology and disease, and to explore its therapeutic potential in treating various diseases, including pain, addiction, and autoimmune disorders.

Genular Protein ID: 501305703

Symbol: OPRK_HUMAN

Name: Kappa-type opioid receptor

UniProtKB Accession Codes:

P41145 E5RHC9 Q499G4

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChEMBL 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 56 DrugCentral 1 EMBL 9 EMDB 11 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 48 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 19 PDBsum 19 PIR 1 PRINTS 3 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 3 RefSeq 3 SIGNOR 1 SMART 1 SMR 1 SUPFAM 1 SignaLink 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 8060324

Title: Isolation of a human kappa opioid receptor cDNA from placenta.

PubMed ID: 8060324

DOI: 10.1006/bbrc.1994.2091

PubMed ID: 7624359

Title: Kappa-opioid receptor in humans: cDNA and genomic cloning, chromosomal assignment, functional expression, pharmacology, and expression pattern in the central nervous system.

PubMed ID: 7624359

DOI: 10.1073/pnas.92.15.7006

PubMed ID: 7869844

Title: Cloning of a human kappa opioid receptor from the brain.

PubMed ID: 7869844

DOI: 10.1016/0024-3205(94)00507-o

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7929306

Title: Human kappa opiate receptor second extracellular loop elevates dynorphin's affinity for human mu/kappa chimeras.

PubMed ID: 7929306

DOI: 10.1016/s0021-9258(18)47144-x

PubMed ID: 12004055

Title: Ezrin-radixin-moesin-binding phosphoprotein-50/Na+/H+ exchanger regulatory factor (EBP50/NHERF) blocks U50,488H-induced down-regulation of the human kappa opioid receptor by enhancing its recycling rate.

PubMed ID: 12004055

DOI: 10.1074/jbc.m200058200

PubMed ID: 16431922

Title: GEC1 interacts with the kappa opioid receptor and enhances expression of the receptor.

PubMed ID: 16431922

DOI: 10.1074/jbc.m509805200

PubMed ID: 17711303

Title: N-glycosylation of the human kappa opioid receptor enhances its stability but slows its trafficking along the biosynthesis pathway.

PubMed ID: 17711303

DOI: 10.1021/bi700443j

PubMed ID: 20729876

Title: The role of kappa-opioid receptor activation in mediating antinociception and addiction.

PubMed ID: 20729876

DOI: 10.1038/aps.2010.138

PubMed ID: 20401607

Title: Kinase cascades and ligand-directed signaling at the kappa opioid receptor.

PubMed ID: 20401607

DOI: 10.1007/s00213-010-1806-y

PubMed ID: 22437504

Title: Structure of the human kappa-opioid receptor in complex with JDTic.

PubMed ID: 22437504

DOI: 10.1038/nature10939

Sequence Information:

  • Length: 380
  • Mass: 42645
  • Checksum: 3DA6E9F90FB48825
  • Sequence:
    • MDSPIQIFRG EPGPTCAPSA CLPPNSSAWF PGWAEPDSNG SAGSEDAQLE PAHISPAIPV 
IITAVYSVVF VVGLVGNSLV MFVIIRYTKM KTATNIYIFN LALADALVTT TMPFQSTVYL 
MNSWPFGDVL CKIVISIDYY NMFTSIFTLT MMSVDRYIAV CHPVKALDFR TPLKAKIINI 
CIWLLSSSVG ISAIVLGGTK VREDVDVIEC SLQFPDDDYS WWDLFMKICV FIFAFVIPVL 
IIIVCYTLMI LRLKSVRLLS GSREKDRNLR RITRLVLVVV AVFVVCWTPI HIFILVEALG 
STSHSTAALS SYYFCIALGY TNSSLNPILY AFLDENFKRC FRDFCFPLKM RMERQSTSRV 
RNTVQDPAYL RDIDGMNKPV

Genular Protein ID: 1913547578

Symbol: A0A5F9ZI09_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A5F9ZI09

Database IDs:

ARBA 13 Antibodypedia 1 Bgee 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 1 GeneTree 1 HGNC 1 InterPro 4 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 3 PROSITE 3 PeptideAtlas 2 Pfam 1 Proteomes 2 RefSeq 1 RuleBase 1 SAM 1 SMART 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

Sequence Information:

  • Length: 409
  • Mass: 45773
  • Checksum: 4F2ED3690622D18B
  • Sequence:
    • MDSPIQIFRG EPGPTCAPSA CLPPNSSAWF PGWAEPDSNG SAGSEDAQLE PAHISPAIPV 
IITAVYSVVF VVGLVGNSLV MFVIIRYTKM KTATNIYIFN LALADALVTT TMPFQSTVYL 
MNSWPFGDVL CKIVISIDYY NMFTSIFTLT MMSVDRYIAV CHPVKALDFR TPLKAKIINI 
CIWLLSSSVG ISAIVLGGTK VREDVDVIEC SLQFPDDDYS WWDLFMKICV FIFAFVIPVL 
IIIVCYTLMI LRLKSVRLLS GSREKDRNLR RITRLVLVVV AVFVVCWTPI HIFILVEALG 
STSHSTAALS SYYFCIALGY TNSSLNPILY AFLDENFKRC FRDFCFPLKM RMERQSTSRV 
RNTVQDPAYL RDIDGMNKPV XLVVEMSSYS SSGREEFNDL GLTQITTAV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.