Details for: OVGP1

Gene ID: 5016

Symbol: OVGP1

Ensembl ID: ENSG00000085465

Description: oviductal glycoprotein 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 32.2736
    Cell Significance Index: -5.0200
  • Cell Name: peg cell (CL4033014)
    Fold Change: 30.7799
    Cell Significance Index: 711.1200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 19.6733
    Cell Significance Index: -4.9900
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 4.1687
    Cell Significance Index: -3.9800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 4.0715
    Cell Significance Index: -5.0200
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 3.1684
    Cell Significance Index: 49.0200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 2.4135
    Cell Significance Index: 147.9700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.2532
    Cell Significance Index: 65.1000
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: 1.1388
    Cell Significance Index: 15.8000
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 1.1363
    Cell Significance Index: -3.4900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.8062
    Cell Significance Index: 153.4200
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.5897
    Cell Significance Index: 58.3300
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.5476
    Cell Significance Index: 11.9900
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 0.5163
    Cell Significance Index: -1.1300
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 0.4305
    Cell Significance Index: 7.2400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.4101
    Cell Significance Index: 370.2500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.3426
    Cell Significance Index: 20.5700
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.3394
    Cell Significance Index: 36.9200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.3349
    Cell Significance Index: 67.1900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3011
    Cell Significance Index: 48.9700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.2516
    Cell Significance Index: 7.2500
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.2172
    Cell Significance Index: 5.8200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.1972
    Cell Significance Index: 2.6900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1730
    Cell Significance Index: 11.9700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1691
    Cell Significance Index: 60.6400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.1647
    Cell Significance Index: 7.2900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.1645
    Cell Significance Index: 6.2300
  • Cell Name: glandular epithelial cell (CL0000150)
    Fold Change: 0.1068
    Cell Significance Index: 0.8500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0948
    Cell Significance Index: 2.6500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0860
    Cell Significance Index: 3.9000
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.0815
    Cell Significance Index: 2.3300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0790
    Cell Significance Index: 15.6700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.0675
    Cell Significance Index: 4.5400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0622
    Cell Significance Index: 11.2100
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0543
    Cell Significance Index: 1.4500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0526
    Cell Significance Index: 1.1400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0509
    Cell Significance Index: 1.7900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.0457
    Cell Significance Index: 6.6500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0316
    Cell Significance Index: 3.8900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.0260
    Cell Significance Index: 3.0300
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.0197
    Cell Significance Index: 0.2800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0162
    Cell Significance Index: 1.0200
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.0145
    Cell Significance Index: 0.3000
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0079
    Cell Significance Index: 3.5000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0065
    Cell Significance Index: 4.5100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0064
    Cell Significance Index: 0.1600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0061
    Cell Significance Index: 11.5200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0043
    Cell Significance Index: 6.6800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0029
    Cell Significance Index: 1.6100
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 0.0027
    Cell Significance Index: 0.0400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0025
    Cell Significance Index: 3.4100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0024
    Cell Significance Index: 4.3500
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 0.0019
    Cell Significance Index: 0.0400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0011
    Cell Significance Index: 0.7100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0007
    Cell Significance Index: 0.0200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0045
    Cell Significance Index: -3.3600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0051
    Cell Significance Index: -3.8700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0051
    Cell Significance Index: -0.1400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0053
    Cell Significance Index: -2.4000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0058
    Cell Significance Index: -4.2300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0064
    Cell Significance Index: -0.3000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0078
    Cell Significance Index: -4.3800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0094
    Cell Significance Index: -0.3000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0122
    Cell Significance Index: -3.5200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0136
    Cell Significance Index: -1.7400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0184
    Cell Significance Index: -2.5300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0223
    Cell Significance Index: -3.8100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0237
    Cell Significance Index: -4.9900
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0244
    Cell Significance Index: -0.4900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0250
    Cell Significance Index: -2.5500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0254
    Cell Significance Index: -3.2800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0287
    Cell Significance Index: -2.0300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0311
    Cell Significance Index: -3.5600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0371
    Cell Significance Index: -1.1800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0395
    Cell Significance Index: -4.6600
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.0402
    Cell Significance Index: -0.3700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0403
    Cell Significance Index: -2.1000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0414
    Cell Significance Index: -3.1800
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0425
    Cell Significance Index: -2.6100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0443
    Cell Significance Index: -4.6100
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0455
    Cell Significance Index: -1.4900
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0477
    Cell Significance Index: -1.1900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0480
    Cell Significance Index: -3.5800
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0491
    Cell Significance Index: -0.9700
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0495
    Cell Significance Index: -1.0700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0497
    Cell Significance Index: -2.6100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0589
    Cell Significance Index: -2.7700
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0646
    Cell Significance Index: -3.2600
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0671
    Cell Significance Index: -2.3500
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.0691
    Cell Significance Index: -0.5700
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0698
    Cell Significance Index: -4.5000
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -0.0705
    Cell Significance Index: -0.9400
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0716
    Cell Significance Index: -1.8400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0741
    Cell Significance Index: -4.1600
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.0847
    Cell Significance Index: -3.1100
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0875
    Cell Significance Index: -1.5000
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.0890
    Cell Significance Index: -1.1100
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0909
    Cell Significance Index: -2.1800
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0946
    Cell Significance Index: -3.8800
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.1006
    Cell Significance Index: -2.1000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Expression Pattern:** OVGP1 is widely expressed in various tissues, including the oviduct, kidney, brain, and intestinal epithelium, highlighting its diverse roles in different cell types and systems. 2. **Structural Features:** OVGP1 is a glycoprotein, suggesting its involvement in carbohydrate metabolism and interactions with other molecules. 3. **Cellular Localization:** OVGP1 is primarily localized to the extracellular region, cytosol, and intracellular membrane-bounded organelles, indicating its role in cell-cell interactions and signaling pathways. **Pathways and Functions:** 1. **Reproductive Processes:** OVGP1 is involved in fertilization, interaction with cumulus cells, and the zona pellucida, suggesting its role in the preparation of the oviduct for fertilization. 2. **Immune Function:** OVGP1 is expressed in immune cells, such as early T lineage precursors and GABAergic interneurons, indicating its involvement in immune responses and regulation. 3. **Cell Signaling:** OVGP1 interacts with chitinases and other molecules, suggesting its role in signaling pathways involved in cell growth, differentiation, and survival. 4. **Transport and Storage:** OVGP1 is involved in the transport of nutrients and waste in various tissues, highlighting its role in maintaining cellular homeostasis. **Clinical Significance:** 1. **Reproductive Disorders:** Alterations in OVGP1 expression or function may contribute to reproductive disorders, such as infertility, miscarriage, or ectopic pregnancy. 2. **Immune-Mediated Diseases:** OVGP1's role in immune responses suggests its involvement in autoimmune diseases, such as multiple sclerosis or type 1 diabetes. 3. **Cancer:** OVGP1's expression in various tissues and its involvement in cell signaling pathways make it a potential biomarker or therapeutic target for cancer diagnosis or treatment. 4. **Developmental Disorders:** OVGP1's expression in neural cells and its role in neuronal development suggest its involvement in developmental disorders, such as autism or schizophrenia. In conclusion, OVGP1 is a multifunctional gene that plays critical roles in reproductive processes, immune function, and cellular signaling pathways. Further research is needed to fully elucidate OVGP1's functions and its clinical significance, but its involvement in various biological processes makes it an attractive target for therapeutic intervention.

Genular Protein ID: 1676518949

Symbol: OVGP1_HUMAN

Name: Oviduct-specific glycoprotein

UniProtKB Accession Codes:

Q12889 A0AV19 B9EGE1 Q15841

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CAZy 1 CCDS 1 CDD 1 CPTAC 3 CTD 1 ChEBI 5 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 14 Ensembl 1 GO 14 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 1 RefSeq 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 7819450

Title: Complementary deoxyribonucleic acid cloning and molecular characterization of an estrogen-dependent human oviductal glycoprotein.

PubMed ID: 7819450

DOI: 10.1095/biolreprod51.4.685

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 678
  • Mass: 75421
  • Checksum: 245F2CEDCE92768B
  • Sequence:
    • MWKLLLWVGL VLVLKHHDGA AHKLVCYFTN WAHSRPGPAS ILPHDLDPFL CTHLIFAFAS 
MNNNQIVAKD LQDEKILYPE FNKLKERNRE LKTLLSIGGW NFGTSRFTTM LSTFANREKF 
IASVISLLRT HDFDGLDLFF LYPGLRGSPM HDRWTFLFLI EELLFAFRKE ALLTMRPRLL 
LSAAVSGVPH IVQTSYDVRF LGRLLDFINV LSYDLHGSWE RFTGHNSPLF SLPEDPKSSA 
YAMNYWRKLG APSEKLIMGI PTYGRTFRLL KASKNGLQAR AIGPASPGKY TKQEGFLAYF 
EICSFVWGAK KHWIDYQYVP YANKGKEWVG YDNAISFSYK AWFIRREHFG GAMVWTLDMD 
DVRGTFCGTG PFPLVYVLND ILVRAEFSST SLPQFWLSSA VNSSSTDPER LAVTTAWTTD 
SKILPPGGEA GVTEIHGKCE NMTITPRGTT VTPTKETVSL GKHTVALGEK TEITGAMTMT 
SVGHQSMTPG EKALTPVGHQ SVTTGQKTLT SVGYQSVTPG EKTLTPVGHQ SVTPVSHQSV 
SPGGTTMTPV HFQTETLRQN TVAPRRKAVA REKVTVPSRN ISVTPEGQTM PLRGENLTSE 
VGTHPRMGNL GLQMEAENRM MLSSSPVIQL PEQTPLAFDN RFVPIYGNHS SVNSVTPQTS 
PLSLKKEIPE NSAVDEEA

Genular Protein ID: 3090967193

Symbol: Q86YN0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q86YN0

Database IDs:

ARBA 9 AlphaFoldDB 1 BioGRID-ORCS 1 CAZy 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 7 Gene3D 2 InterPro 5 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 1 SAM 2 SMART 1 SMR 1 SUPFAM 2

Sequence Information:

  • Length: 678
  • Mass: 75372
  • Checksum: 3518DC14029B5A56
  • Sequence:
    • MWKLLLWVGL VLVLKHHDGA AHKLVCYFTN WAHSRPGPAS ILPHDLDPFL CTHLIFAFAS 
MNNNQIVAKD LQDEKILYPE FNKLKERNRE LKTLLSIGGW NFGTSRFTTM LSTFANREKF 
IASVISLLRT HDFDGLDLFF LYPGLRGSPM HDRWTFLFLI EELLFAFRKE ALLTMRPRLL 
LSAAVSGVPH IVQTSYDVRF LGRLLDFINV LSYDLHGSWE RFTGHNSPLF SLPEDPKSSA 
YAMNYWRKLG APSEKLIMGI PTYGRTFRLL KASKNGLQAR AIGPASPGKY TKQEGFLAYF 
EICSFVWGAK KHWIDYQYVP YANKGKEWVG YENAISFSYK AWFIRREHFG GAMVWTLDMD 
DVRGTFCGTG PFPLVYVLND ILVRAEFSST SLPQFWLSSA VNSSSTDPER LAVTTAWTTD 
SKILPPGGEA GVTEIHGKCE NMTITPRGTT VTPTKETVSL GKHTVALGEK TEITGATTVT 
SVGHQSMTPG EKALTPVGHQ SVTTGQKTLT SVGYQSVTPG EKTLTPVGHQ SVTPVSHQSV 
SPGGTTMTPV HFQTETLRQN TVAPRRKAVA REKVTVPSRN ISVTPEGQTM PLRGENLTSE 
VGTHPRMGNL GLQMEAENRM MLSSSPVIQL PEQTPLAFDN RFVPIYGNHS SVNSVTPQTS 
PLSLKKEIPE NSAVDQEA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.