Details for: DCAF8

Gene ID: 50717

Symbol: DCAF8

Ensembl ID: ENSG00000132716

Description: DDB1 and CUL4 associated factor 8

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 204.0886
    Cell Significance Index: -31.7500
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 123.7170
    Cell Significance Index: -31.3800
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 76.9503
    Cell Significance Index: -36.3300
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 75.9987
    Cell Significance Index: -30.8800
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 68.1202
    Cell Significance Index: -35.0400
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 32.6475
    Cell Significance Index: -31.1700
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 25.4591
    Cell Significance Index: -31.3900
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 12.8898
    Cell Significance Index: -34.5300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 8.7125
    Cell Significance Index: -34.3800
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 7.7950
    Cell Significance Index: -17.0600
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 1.7629
    Cell Significance Index: 21.0200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.6818
    Cell Significance Index: 337.3600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.4140
    Cell Significance Index: 1276.7000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 1.3058
    Cell Significance Index: 152.1800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.1314
    Cell Significance Index: 63.4900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.1051
    Cell Significance Index: 57.5700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.0973
    Cell Significance Index: 84.2100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.0072
    Cell Significance Index: 109.5500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.9763
    Cell Significance Index: 61.5300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.9144
    Cell Significance Index: 327.9900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.8387
    Cell Significance Index: 151.1900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.6797
    Cell Significance Index: 83.5800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.6530
    Cell Significance Index: 451.6500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.6215
    Cell Significance Index: 8.4800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.5742
    Cell Significance Index: 16.5500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.5604
    Cell Significance Index: 12.1400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.5171
    Cell Significance Index: 14.4500
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.5164
    Cell Significance Index: 35.7100
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 0.4709
    Cell Significance Index: 3.6300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.3856
    Cell Significance Index: 76.5200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.3789
    Cell Significance Index: 23.2900
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.3562
    Cell Significance Index: 8.2300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.3055
    Cell Significance Index: 41.9500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.2991
    Cell Significance Index: 13.2300
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.2847
    Cell Significance Index: 10.7800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2805
    Cell Significance Index: 153.2000
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.2801
    Cell Significance Index: 14.1600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.2700
    Cell Significance Index: 12.5900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.2122
    Cell Significance Index: 27.2000
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1969
    Cell Significance Index: 87.0400
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.1797
    Cell Significance Index: 1.6600
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.1549
    Cell Significance Index: 3.3100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1500
    Cell Significance Index: 6.8000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.1342
    Cell Significance Index: 21.8200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.1286
    Cell Significance Index: 3.5000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.1252
    Cell Significance Index: 14.7600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.1190
    Cell Significance Index: 6.2500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.1036
    Cell Significance Index: 17.6900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0930
    Cell Significance Index: 4.8300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0751
    Cell Significance Index: 4.8500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0611
    Cell Significance Index: 2.8700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0353
    Cell Significance Index: 6.7100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.0352
    Cell Significance Index: 2.6200
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0273
    Cell Significance Index: 2.7000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0106
    Cell Significance Index: 20.0000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0030
    Cell Significance Index: -0.0800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0070
    Cell Significance Index: -12.9500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0073
    Cell Significance Index: -4.5500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0087
    Cell Significance Index: -13.3900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0097
    Cell Significance Index: -1.2500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0098
    Cell Significance Index: -7.2900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0147
    Cell Significance Index: -10.7600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0175
    Cell Significance Index: -11.1100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0209
    Cell Significance Index: -15.8500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0228
    Cell Significance Index: -31.0100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0259
    Cell Significance Index: -14.5900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0368
    Cell Significance Index: -16.7100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0571
    Cell Significance Index: -5.8300
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0643
    Cell Significance Index: -1.6900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0705
    Cell Significance Index: -10.2500
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: -0.0828
    Cell Significance Index: -0.8800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0837
    Cell Significance Index: -17.6200
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0845
    Cell Significance Index: -1.4200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0903
    Cell Significance Index: -10.3500
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0917
    Cell Significance Index: -2.2000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1217
    Cell Significance Index: -35.0300
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.1535
    Cell Significance Index: -4.4000
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.1582
    Cell Significance Index: -18.0600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1819
    Cell Significance Index: -12.8700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.2342
    Cell Significance Index: -8.1400
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.2612
    Cell Significance Index: -6.5300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.3076
    Cell Significance Index: -20.6800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3141
    Cell Significance Index: -32.7100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.3194
    Cell Significance Index: -10.2300
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.3687
    Cell Significance Index: -9.4200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3771
    Cell Significance Index: -29.8700
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.4226
    Cell Significance Index: -8.9700
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.4386
    Cell Significance Index: -12.8800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4994
    Cell Significance Index: -30.6200
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -0.5040
    Cell Significance Index: -7.0700
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.5237
    Cell Significance Index: -16.6800
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.5929
    Cell Significance Index: -4.8400
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.5971
    Cell Significance Index: -19.5500
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.6180
    Cell Significance Index: -12.2200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.6506
    Cell Significance Index: -13.8600
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.6576
    Cell Significance Index: -8.2000
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.6708
    Cell Significance Index: -11.3000
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.6899
    Cell Significance Index: -13.8500
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.7208
    Cell Significance Index: -21.2300
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.7218
    Cell Significance Index: -12.3700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** DCAF8 is a protein-coding gene that is significantly expressed in various cell types, including polychromatophilic erythroblasts, hematopoietic oligopotent progenitor cells, and smooth muscle fibers of the ileum. It belongs to the Cul4-Ring E3 ubiquitin ligase complex, which is involved in the regulation of protein ubiquitination and neddylation. The gene is also associated with the CUL4-RING E3 ubiquitin ligase complex, which is a key player in the regulation of protein degradation and cellular homeostasis. **Pathways and Functions:** DCAF8 is involved in several key pathways, including: 1. **Cul4-Ring E3 Ubiquitin Ligase Complex:** This complex is responsible for the ubiquitination and neddylation of proteins, which play a crucial role in the regulation of protein degradation and cellular homeostasis. 2. **Protein Binding:** DCAF8 interacts with various proteins, including DDB1 and CUL4, to regulate protein ubiquitination and neddylation. 3. **Metabolism of Proteins:** DCAF8 is involved in the regulation of protein metabolism, including protein degradation and synthesis. 4. **Mitochondrion:** DCAF8 is localized to the mitochondria, where it regulates mitochondrial function and biogenesis. 5. **Neddylation:** DCAF8 is involved in the regulation of neddylation, a post-translational modification that plays a crucial role in protein degradation and cellular homeostasis. **Clinical Significance:** DCAF8 has been implicated in various diseases, including: 1. **Immunodeficiency Disorders:** Mutations in the DCAF8 gene have been associated with immunodeficiency disorders, including severe combined immunodeficiency (SCID) and hyper IgM syndrome. 2. **Cancer:** DCAF8 has been implicated in the regulation of cancer cell growth and survival, and its dysregulation has been associated with various types of cancer, including breast cancer and lung cancer. 3. **Neurological Disorders:** DCAF8 has been implicated in the regulation of neuronal function and survival, and its dysregulation has been associated with various neurological disorders, including Alzheimer's disease and Parkinson's disease. In conclusion, DCAF8 is a gene that plays a crucial role in immune regulation and cellular homeostasis. Its dysregulation has been implicated in various diseases, including immunodeficiency disorders, cancer, and neurological disorders. Further research is needed to fully understand the role of DCAF8 in human disease and to develop effective therapeutic strategies for the treatment of these conditions. **Recommendations:** 1. **Immunodeficiency Disorders:** Further research is needed to understand the mechanisms underlying immunodeficiency disorders caused by DCAF8 mutations. 2. **Cancer:** DCAF8 could be a potential therapeutic target for the treatment of cancer, and further research is needed to understand its role in cancer cell growth and survival. 3. **Neurological Disorders:** DCAF8 could be a potential therapeutic target for the treatment of neurological disorders, and further research is needed to understand its role in neuronal function and survival. In summary, DCAF8 is a gene that plays a crucial role in immune regulation and cellular homeostasis. Its dysregulation has been implicated in various diseases, including immunodeficiency disorders, cancer, and neurological disorders. Further research is needed to fully understand the role of DCAF8 in human disease and to develop effective therapeutic strategies for the treatment of these conditions.

Genular Protein ID: 3749149779

Symbol: DCAF8_HUMAN

Name: DDB1- and CUL4-associated factor 8

UniProtKB Accession Codes:

Q5TAQ9 D3DVE6 Q12839 Q4QQI6 Q53F14 Q66K50 Q68CS7 Q96E00

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChiTaRS 1 ComplexPortal 2 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 12 Ensembl 5 EvolutionaryTrace 1 ExpressionAtlas 1 GO 7 Gene3D 1 GeneCards 1 GeneTree 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 2 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16949367

Title: A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1.

PubMed ID: 16949367

DOI: 10.1016/j.molcel.2006.08.010

PubMed ID: 16964240

Title: Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery.

PubMed ID: 16964240

DOI: 10.1038/nature05175

PubMed ID: 22500989

Title: Characterization of nuclear import and export signals determining the subcellular localization of WD repeat-containing protein 42A (WDR42A).

PubMed ID: 22500989

DOI: 10.1016/j.febslet.2012.02.053

PubMed ID: 23455924

Title: A Y2H-seq approach defines the human protein methyltransferase interactome.

PubMed ID: 23455924

DOI: 10.1038/nmeth.2397

PubMed ID: 24500646

Title: Ubiquitin ligase defect by DCAF8 mutation causes HMSN2 with giant axons.

PubMed ID: 24500646

DOI: 10.1212/wnl.0000000000000206

Sequence Information:

  • Length: 597
  • Mass: 66852
  • Checksum: 3F3396C77EA1E3AD
  • Sequence:
    • MSSKGSSTDG RTDLANGSLS SSPEEMSGAE EGRETSSGIE VEASDLSLSL TGDDGGPNRT 
STESRGTDTE SSGEDKDSDS MEDTGHYSIN DENRVHDRSE EEEEEEEEEE EEQPRRRVQR 
KRANRDQDSS DDERALEDWV SSETSALPRP RWQALPALRE RELGSSARFV YEACGARVFV 
QRFRLQHGLE GHTGCVNTLH FNQRGTWLAS GSDDLKVVVW DWVRRQPVLD FESGHKSNVF 
QAKFLPNSGD STLAMCARDG QVRVAELSAT QCCKNTKRVA QHKGASHKLA LEPDSPCTFL 
SAGEDAVVFT IDLRQDRPAS KLVVTKEKEK KVGLYTIYVN PANTHQFAVG GRDQFVRIYD 
QRKIDENENN GVLKKFCPHH LVNSESKANI TCLVYSHDGT ELLASYNDED IYLFNSSHSD 
GAQYVKRYKG HRNNATVKGV NFYGPKSEFV VSGSDCGHIF LWEKSSCQII QFMEGDKGGV 
VNCLEPHPHL PVLATSGLDH DVKIWAPTAE ASTELTGLKD VIKKNKRERD EDSLHQTDLF 
DSHMLWFLMH HLRQRRHHRR WREPGVGATD ADSDESPSSS DTSDEEEGPD RVQCMPS

Genular Protein ID: 1806077226

Symbol: B7Z8C9_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z8C9

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 2 Gene3D 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 Pfam 1 PharmGKB 1 ProteomicsDB 1 RefSeq 1 SAM 1 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 578
  • Mass: 64867
  • Checksum: 240873D8452D6A29
  • Sequence:
    • MSSKGSSTDG RTDLANGSLS SSPEEMSGAE EGRETSSGIE VEASDLSLSL TGDDGGPNRT 
SMEDTGHYSI NDENRVHDRS EEEEEEEEEE EEEQPRRRVQ RKRANRDQDS SDDERALEDW 
VSSETSALPR PRWQALPALR ERELGSSARF VYEACGARVF VQRFRLQHGL EGHTGCVNTL 
HFNQRGTWLA SGSDDLKVVV WDWVRRQPVL DFESGHKSNV FQAKFLPNSG DSTLAMCARD 
GQVRVAELSA TQCCKNTKRV AQHKGASHKL ALEPDSPCTF LSAGEDAVVF TIDLRQDRPA 
SKLVVTKEKE KKVGLYTIYV NPANTHQFAV GGRDQFVRIY DQRKIDENEN NGVLKKFCPH 
HLVNSESKAN ITCLVYSHDG TELLASYNDE DIYLFNSSHS DGAQYVKRYK GHRNNATVKG 
VNFYGPKSEF VVSGSDCGHI FLWEKSSCQI IQFMEGDKGG VVNCLEPHPH LPVLATSGLD 
HDVKIWAPTA EASTELTGLK DVIKKNKRER DEDSLHQTDL FDSHMLWFLM HHLRQRRHHR 
RWREPGVGAT DADSDESPSS SDTSDEEEGP DRVQCMPS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.