Details for: SHANK1

Gene ID: 50944

Symbol: SHANK1

Ensembl ID: ENSG00000161681

Description: SH3 and multiple ankyrin repeat domains 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 1.6910
    Cell Significance Index: 40.9600
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 1.6400
    Cell Significance Index: 35.9100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.3054
    Cell Significance Index: 261.8600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.0199
    Cell Significance Index: 705.3900
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.8712
    Cell Significance Index: 24.8600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.8708
    Cell Significance Index: 312.3300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.5602
    Cell Significance Index: 15.0100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.5402
    Cell Significance Index: 36.3200
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: 0.4685
    Cell Significance Index: 6.2500
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 0.4035
    Cell Significance Index: 3.1000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.3615
    Cell Significance Index: 22.2200
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.3040
    Cell Significance Index: 7.2900
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 0.2988
    Cell Significance Index: 7.4500
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: 0.1373
    Cell Significance Index: 1.7800
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0636
    Cell Significance Index: 1.0900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0024
    Cell Significance Index: 4.5300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0000
    Cell Significance Index: -0.0100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0035
    Cell Significance Index: -6.4100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0045
    Cell Significance Index: -0.2900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0055
    Cell Significance Index: -7.4900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0161
    Cell Significance Index: -10.2500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0163
    Cell Significance Index: -12.1100
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0165
    Cell Significance Index: -0.3500
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0179
    Cell Significance Index: -0.3600
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0189
    Cell Significance Index: -0.2700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0218
    Cell Significance Index: -0.6100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0221
    Cell Significance Index: -12.4600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0226
    Cell Significance Index: -10.2500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0238
    Cell Significance Index: -14.8600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0243
    Cell Significance Index: -13.2700
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.0310
    Cell Significance Index: -0.2100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0375
    Cell Significance Index: -10.8000
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0405
    Cell Significance Index: -0.8000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0446
    Cell Significance Index: -1.4600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0468
    Cell Significance Index: -9.2900
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: -0.0504
    Cell Significance Index: -0.4800
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0506
    Cell Significance Index: -1.6100
  • Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
    Fold Change: -0.0580
    Cell Significance Index: -0.6400
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0583
    Cell Significance Index: -2.5300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0622
    Cell Significance Index: -9.0400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0626
    Cell Significance Index: -11.2800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0684
    Cell Significance Index: -11.6800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0685
    Cell Significance Index: -14.4300
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0782
    Cell Significance Index: -1.6900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0802
    Cell Significance Index: -4.5000
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0834
    Cell Significance Index: -2.0800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0890
    Cell Significance Index: -12.2200
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0973
    Cell Significance Index: -1.0600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0984
    Cell Significance Index: -12.1000
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.1129
    Cell Significance Index: -1.0700
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.1131
    Cell Significance Index: -1.3200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1137
    Cell Significance Index: -13.4100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1174
    Cell Significance Index: -13.4500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1218
    Cell Significance Index: -7.8600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1259
    Cell Significance Index: -13.1100
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.1259
    Cell Significance Index: -1.5700
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -0.1435
    Cell Significance Index: -1.7400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1435
    Cell Significance Index: -11.0100
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.1519
    Cell Significance Index: -3.1700
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.1625
    Cell Significance Index: -2.0500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1666
    Cell Significance Index: -7.7700
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.1673
    Cell Significance Index: -5.8600
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.1941
    Cell Significance Index: -2.4500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2124
    Cell Significance Index: -11.1500
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.2284
    Cell Significance Index: -5.8700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2311
    Cell Significance Index: -10.2200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2329
    Cell Significance Index: -8.8200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.2511
    Cell Significance Index: -13.0800
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.2601
    Cell Significance Index: -3.1100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.2678
    Cell Significance Index: -12.5900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.2786
    Cell Significance Index: -12.6300
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.2800
    Cell Significance Index: -5.5100
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: -0.3178
    Cell Significance Index: -3.3100
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.3275
    Cell Significance Index: -6.5300
  • Cell Name: granule cell (CL0000120)
    Fold Change: -0.3636
    Cell Significance Index: -4.1400
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.3641
    Cell Significance Index: -3.0100
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.3721
    Cell Significance Index: -12.9300
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.3803
    Cell Significance Index: -7.9600
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.3842
    Cell Significance Index: -4.7700
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.3872
    Cell Significance Index: -9.6700
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -0.3954
    Cell Significance Index: -5.2700
  • Cell Name: IgA plasma cell (CL0000987)
    Fold Change: -0.3990
    Cell Significance Index: -2.6600
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.4089
    Cell Significance Index: -11.7800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.4141
    Cell Significance Index: -10.8900
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: -0.4150
    Cell Significance Index: -4.1800
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.4183
    Cell Significance Index: -13.2300
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.4385
    Cell Significance Index: -12.5700
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.4390
    Cell Significance Index: -12.9300
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: -0.4427
    Cell Significance Index: -2.8800
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.4453
    Cell Significance Index: -7.7000
  • Cell Name: fast muscle cell (CL0000190)
    Fold Change: -0.4551
    Cell Significance Index: -5.9600
  • Cell Name: L5/6 near-projecting glutamatergic neuron (CL4030067)
    Fold Change: -0.4583
    Cell Significance Index: -2.4000
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.4632
    Cell Significance Index: -9.9000
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.4636
    Cell Significance Index: -10.7100
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.4659
    Cell Significance Index: -12.4400
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.4780
    Cell Significance Index: -12.7900
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.4865
    Cell Significance Index: -9.9000
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.4879
    Cell Significance Index: -9.5400
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.4889
    Cell Significance Index: -11.9300
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.5055
    Cell Significance Index: -12.8800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** SHANK1 is a scaffold protein that interacts with multiple partners, including ionotropic glutamate receptors, AMPA receptors, and neurexins and neuroligins. The protein contains multiple SH3 domains, which are involved in the regulation of actin filament bundle assembly and the maintenance of postsynaptic density structure. SHANK1 also contains ankyrin repeat domains, which are involved in protein-protein interactions and the regulation of synaptic function. The gene is highly expressed in the nervous system, particularly in areas involved in learning and memory, such as the hippocampus. **Pathways and Functions:** SHANK1 is involved in various signaling pathways, including: 1. **Synaptic Plasticity:** SHANK1 regulates synaptic plasticity by interacting with ionotropic glutamate receptors and AMPA receptors, which are critical for the induction of long-term potentiation (LTP) and long-term depression (LTD). 2. **Excitatory Postsynaptic Potential (EPSP):** SHANK1 regulates EPSP by interacting with AMPA receptors and other synaptic receptors, which are involved in the regulation of neuronal excitability. 3. **Long-term Memory Formation:** SHANK1 is involved in the regulation of long-term memory formation by interacting with neurexins and neuroligins, which are critical for the formation of synaptic connections between neurons. 4. **Neurotransmitter Regulation:** SHANK1 regulates neurotransmitter release and uptake by interacting with ionotropic glutamate receptors and other synaptic receptors. **Clinical Significance:** Dysregulation of SHANK1 has been implicated in various neurological disorders, including: 1. **Autism Spectrum Disorder (ASD):** SHANK1 has been shown to be a critical component in the regulation of synaptic function and behavior in individuals with ASD. 2. **Schizophrenia:** SHANK1 has been implicated in the regulation of synaptic function and behavior in individuals with schizophrenia. 3. **Mental Retardation:** SHANK1 has been shown to be a critical component in the regulation of synaptic function and behavior in individuals with mental retardation. In conclusion, SHANK1 is a critical gene that plays a significant role in the regulation of synaptic function and behavior. Further research is needed to fully understand the mechanisms by which SHANK1 regulates synaptic function and behavior, and to explore its therapeutic potential in the treatment of neurological disorders.

Genular Protein ID: 2405328259

Symbol: SHAN1_HUMAN

Name: SH3 and multiple ankyrin repeat domains protein 1

UniProtKB Accession Codes:

Q9Y566 A8MXP5 B7WNY6 Q9NYW9

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 3 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 ELM 1 EMBL 4 Ensembl 2 ExpressionAtlas 1 GO 38 Gene3D 4 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 10 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 6 PDBsum 6 PRO 1 PROSITE 5 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 RNAct 1 Reactome 1 RefSeq 3 SIGNOR 1 SMART 4 SMR 1 STRING 1 SUPFAM 4 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 2 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 10551867

Title: Somatostatin receptor interacting protein defines a novel family of multidomain proteins present in human and rodent brain.

PubMed ID: 10551867

DOI: 10.1074/jbc.274.46.32997

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 10806096

Title: The Shank family of scaffold proteins.

PubMed ID: 10806096

DOI: 10.1242/jcs.113.11.1851

PubMed ID: 12504591

Title: The insulin receptor substrate IRSp53 links postsynaptic shank1 to the small G-protein cdc42.

PubMed ID: 12504591

DOI: 10.1006/mcne.2002.1201

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 2161
  • Mass: 224959
  • Checksum: 94BDE56D3D5F319D
  • Sequence:
    • MTHSPATSED EERHSASECP EGGSESDSSP DGPGRGPRGT RGQGSGAPGS LASVRGLQGR 
SMSVPDDAHF SMMVFRIGIP DLHQTKCLRF NPDATIWTAK QQVLCALSES LQDVLNYGLF 
QPATSGRDAN FLEEERLLRE YPQSFEKGVP YLEFRYKTRV YKQTNLDEKQ LAKLHTKTGL 
KKFLEYVQLG TSDKVARLLD KGLDPNYHDS DSGETPLTLA AQTEGSVEVI RTLCLGGAHI 
DFRARDGMTA LHKAACARHC LALTALLDLG GSPNYKDRRG LTPLFHTAMV GGDPRCCELL 
LFNRAQLGIA DENGWQEIHQ ACQRGHSQHL EHLLFYGAEP GAQNASGNTA LHICALYNKE 
TCARILLYRG ADKDVKNNNG QTPFQVAVIA GNFELGELIR NHREQDVVPF QESPKYAARR 
RGPPGTGLTV PPALLRANSD TSMALPDWMV FSAPGAASSG APGPTSGSQG QSQPSAPTTK 
LSSGTLRSAS SPRGARARSP SRGRHPEDAK RQPRGRPSSS GTPREGPAGG TGGSGGPGGS 
LGSRGRRRKL YSAVPGRSFM AVKSYQAQAE GEISLSKGEK IKVLSIGEGG FWEGQVKGRV 
GWFPSDCLEE VANRSQESKQ ESRSDKAKRL FRHYTVGSYD SFDAPSLMDG IGPGSDYIIK 
EKTVLLQKKD SEGFGFVLRG AKAQTPIEEF TPTPAFPALQ YLESVDEGGV AWRAGLRMGD 
FLIEVNGQNV VKVGHRQVVN MIRQGGNTLM VKVVMVTRHP DMDEAVHKKA PQQAKRLPPP 
TISLRSKSMT SELEEMEYEQ QPAPVPSMEK KRTVYQMALN KLDEILAAAQ QTISASESPG 
PGGLASLGKH RPKGFFATES SFDPHHRAQP SYERPSFLPP GPGLMLRQKS IGAAEDDRPY 
LAPPAMKFSR SLSVPGSEDI PPPPTTSPPE PPYSTPPVPS SSGRLTPSPR GGPFNPGSGG 
PLPASSPASF DGPSPPDTRV GSREKSLYHS GPLPPAHHHP PHHHHHHAPP PQPHHHHAHP 
PHPPEMETGG SPDDPPPRLA LGPQPSLRGW RGGGPSPTPG APSPSHHGSA GGGGGSSQGP 
ALRYFQLPPR AASAAMYVPA RSGRGRKGPL VKQTKVEGEP QKGGGLPPAP SPTSPASPQP 
PPAVAAPSEK NSIPIPTIII KAPSTSSSGR SSQGSSTEAE PPTQPEPTGG GGGGGSSPSP 
APAMSPVPPS PSPVPTPASP SGPATLDFTS QFGAALVGAA RREGGWQNEA RRRSTLFLST 
DAGDEDGGDG GLGTGAAPGP RLRHSKSIDE GMFSAEPYLR LESAGSGAGY GGYGAGSRAY 
GGGGGSSAFT SFLPPRPLVH PLTGKALDPA SPLGLALAAR ERALKESSEG GGAPQPPPRP 
PSPRYEAPPP TPHHHSPHAH HEPVLRLWGA SPPDPARREL GYRAGLGSQE KSLPASPPAA 
RRSLLHRLPP TAPGVGPLLL QLGTEPPAPH PGVSKPWRSA APEEPERLPL HVRFLENCQP 
RAPVTSGRGP PSEDGPGVPP PSPRRSVPPS PTSPRASEEN GLPLLVLPPP APSVDVEDGE 
FLFVEPLPPP LEFSNSFEKP ESPLTPGPPH PLPDTPAPAT PLPPVPPPAV AAAPPTLDST 
ASSLTSYDSE VATLTQGASA APGDPHPPGP PAPAAPAPAA PQPGPDPPPG TDSGIEEVDS 
RSSSDHPLET ISSASTLSSL SAEGGGSAGG GGGAGAGVAS GPELLDTYVA YLDGQAFGGS 
STPGPPYPPQ LMTPSKLRGR ALGASGGLRP GPSGGLRDPV TPTSPTVSVT GAGTDGLLAL 
RACSGPPTAG VAGGPVAVEP EVPPVPLPTA SSLPRKLLPW EEGPGPPPPP LPGPLAQPQA 
SALATVKASI ISELSSKLQQ FGGSSAAGGA LPWARGGSGG GGDSHHGGAS YVPERTSSLQ 
RQRLSDDSQS SLLSKPVSSL FQNWPKPPLP PLPTGTGVSP TAAAAPGATS PSASSSSTST 
RHLQGVEFEM RPPLLRRAPS PSLLPASEHK VSPAPRPSSL PILPSGPLYP GLFDIRGSPT 
GGAGGSADPF APVFVPPHPG ISGGLGGALS GASRSLSPTR LLSLPPDKPF GAKPLGFWTK 
FDVADWLEWL GLAEHRAQFL DHEIDGSHLP ALTKEDYVDL GVTRVGHRMN IDRALKFFLE 
R

Genular Protein ID: 3262721361

Symbol: H9KV90_HUMAN

Name: N/A

UniProtKB Accession Codes:

H9KV90

Database IDs:

ARBA 4 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 2 Gene3D 4 GeneTree 1 HGNC 1 InterPro 10 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 8 PROSITE-ProRule 2 PeptideAtlas 1 Pfam 4 PhylomeDB 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 1 SMART 4 SMR 1 SUPFAM 4 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

Sequence Information:

  • Length: 2169
  • Mass: 225900
  • Checksum: A1D0D542CE8F94C6
  • Sequence:
    • MTHSPATSED EERHSASECP EGGSESDSSP DGPGRGPRGT RGQGSGAPGS LASVRGLQGR 
SMSVPDDAHF SMMVFRIGIP DLHQTKCLRF NPDATIWTAK QQVLCALSES LQDVLNYGLF 
QPATSGRDAN FLEEERLLRE YPQSFEKGVP YLEFRYKTRV YKQTNLDEKQ LAKLHTKTGL 
KKFLEYVQLG TSDKVARLLD KGLDPNYHDS DSGETPLTLA AQTEGSVEVI RTLCLGGAHI 
DFRARDGMTA LHKAACARHC LALTALLDLG GSPNYKDRRG LTPLFHTAMV GGDPRCCELL 
LFNRAQLGIA DENGWQEIHQ ACQRGHSQHL EHLLFYGAEP GAQNASGNTA LHICALYNKE 
TCARILLYRG ADKDVKNNNG QTPFQVAVIA GNFELGELIR NHREQDVVPF QESPKYAARR 
RGPPGTGLTV PPALLRANSD TSMALPDWMV FSAPGAASSG APGPTSGSQG QSQPSAPTTK 
LSSGTLRSAS SPRGARARSP SRGRHPEDAK RQPRGRPSSS GTPREGPAGG TGGSGGPGGS 
LGSRGRRRKL YSAVPGRSFM AVKSYQAQAE GEISLSKGEK IKVLSIGEGG FWEGQVKGRV 
GWFPSDCLEE VANRSQESKQ ESRSDKAKRL FRHYTVGSYD SFDAPSLMDG IGPGSDYIIK 
EKTVLLQKKD SEGFGFVLRG AKAQTPIEEF TPTPAFPALQ YLESVDEGGV AWRAGLRMGD 
FLIEVNGQNV VKVGHRQVVN MIRQGGNTLM VKVVMVTRHP DMDEAVHKKA PQQAKRLPPP 
TISLRSKSMT SELEEMVSPW KKKSEYEQQP APVPSMEKKR TVYQMALNKL DEILAAAQQT 
ISASESPGPG GLASLGKHRP KGFFATESSF DPHHRAQPSY ERPSFLPPGP GLMLRQKSIG 
AAEDDRPYLA PPAMKFSRSL SVPGSEDIPP PPTTSPPEPP YSTPPVPSSS GRLTPSPRGG 
PFNPGSGGPL PASSPASFDG PSPPDTRVGS REKSLYHSGP LPPAHHHPPH HHHHHAPPPQ 
PHHHHAHPPH PPEMETGGSP DDPPPRLALG PQPSLRGWRG GGPSPTPGAP SPSHHGSAGG 
GGGSSQGPAL RYFQLPPRAA SAAMYVPARS GRGRKGPLVK QTKVEGEPQK GGGLPPAPSP 
TSPASPQPPP AVAAPSEKNS IPIPTIIIKA PSTSSSGRSS QGSSTEAEPP TQPEPTGGGG 
GGGSSPSPAP AMSPVPPSPS PVPTPASPSG PATLDFTSQF GAALVGAARR EGGWQNEARR 
RSTLFLSTDA GDEDGGDGGL GTGAAPGPRL RHSKSIDEGM FSAEPYLRLE SAGSGAGYGG 
YGAGSRAYGG GGGSSAFTSF LPPRPLVHPL TGKALDPASP LGLALAARER ALKESSEGGG 
APQPPPRPPS PRYEAPPPTP HHHSPHAHHE PVLRLWGASP PDPARRELGY RAGLGSQEKS 
LPASPPAARR SLLHRLPPTA PGVGPLLLQL GTEPPAPHPG VSKPWRSAAP EEPERLPLHV 
RFLENCQPRA PVTSGRGPPS EDGPGVPPPS PRRSVPPSPT SPRASEENGL PLLVLPPPAP 
SVDVEDGEFL FVEPLPPPLE FSNSFEKPES PLTPGPPHPL PDTPAPATPL PPVPPPAVAA 
APPTLDSTAS SLTSYDSEVA TLTQGASAAP GDPHPPGPPA PAAPAPAAPQ PGPDPPPGTD 
SGIEEVDSRS SSDHPLETIS SASTLSSLSA EGGGSAGGGG GAGAGVASGP ELLDTYVAYL 
DGQAFGGSST PGPPYPPQLM TPSKLRGRAL GASGGLRPGP SGGLRDPVTP TSPTVSVTGA 
GTDGLLALRA CSGPPTAGVA GGPVAVEPEV PPVPLPTASS LPRKLLPWEE GPGPPPPPLP 
GPLAQPQASA LATVKASIIS ELSSKLQQFG GSSAAGGALP WARGGSGGGG DSHHGGASYV 
PERTSSLQRQ RLSDDSQSSL LSKPVSSLFQ NWPKPPLPPL PTGTGVSPTA AAAPGATSPS 
ASSSSTSTRH LQGVEFEMRP PLLRRAPSPS LLPASEHKVS PAPRPSSLPI LPSGPLYPGL 
FDIRGSPTGG AGGSADPFAP VFVPPHPGIS GGLGGALSGA SRSLSPTRLL SLPPDKPFGA 
KPLGFWTKFD VADWLEWLGL AEHRAQFLDH EIDGSHLPAL TKEDYVDLGV TRVGHRMNID 
RALKFFLER

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.