Details for: TRIM33

Gene ID: 51592

Symbol: TRIM33

Ensembl ID: ENSG00000197323

Description: tripartite motif containing 33

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 371.4032
    Cell Significance Index: -57.7700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 231.7033
    Cell Significance Index: -58.7700
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 134.4884
    Cell Significance Index: -63.5000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 127.5547
    Cell Significance Index: -51.8200
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 114.0002
    Cell Significance Index: -58.6400
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 94.7435
    Cell Significance Index: -63.5800
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 54.4545
    Cell Significance Index: -51.9900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 50.5858
    Cell Significance Index: -62.3700
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 22.3603
    Cell Significance Index: -59.9000
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 17.4054
    Cell Significance Index: -53.4600
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 16.0616
    Cell Significance Index: -63.3800
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 12.2088
    Cell Significance Index: -26.7200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 5.7214
    Cell Significance Index: 152.7700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 2.7651
    Cell Significance Index: 155.1700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.3855
    Cell Significance Index: 478.5200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 2.2384
    Cell Significance Index: 30.5400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.9877
    Cell Significance Index: 394.4700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.9183
    Cell Significance Index: 53.6100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.7002
    Cell Significance Index: 609.8400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 1.3771
    Cell Significance Index: 92.6000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.2956
    Cell Significance Index: 896.0800
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 1.2432
    Cell Significance Index: 15.4200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 1.1143
    Cell Significance Index: 49.2900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.0856
    Cell Significance Index: 83.3100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.0703
    Cell Significance Index: 116.4200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 1.0671
    Cell Significance Index: 40.4100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.0510
    Cell Significance Index: 189.4600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.9101
    Cell Significance Index: 55.9400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.8982
    Cell Significance Index: 110.4500
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.8376
    Cell Significance Index: 21.5300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.7677
    Cell Significance Index: 19.1900
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.7321
    Cell Significance Index: 43.9500
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.7041
    Cell Significance Index: 15.0500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.6007
    Cell Significance Index: 542.3700
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.5435
    Cell Significance Index: 15.5100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.5344
    Cell Significance Index: 73.3900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.5053
    Cell Significance Index: 275.9800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.4545
    Cell Significance Index: 13.1000
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.4249
    Cell Significance Index: 10.1900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.4108
    Cell Significance Index: 181.6400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.3667
    Cell Significance Index: 19.0500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.2843
    Cell Significance Index: 6.1600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.2613
    Cell Significance Index: 165.9500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.2256
    Cell Significance Index: 424.7000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.2230
    Cell Significance Index: 14.3900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.2171
    Cell Significance Index: 3.7200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.1855
    Cell Significance Index: 31.6800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1696
    Cell Significance Index: 32.2700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.1578
    Cell Significance Index: 71.6400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1514
    Cell Significance Index: 7.0600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.1259
    Cell Significance Index: 193.8400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.1115
    Cell Significance Index: 205.5700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0924
    Cell Significance Index: 4.1900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0883
    Cell Significance Index: 8.7300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0811
    Cell Significance Index: 110.2100
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0046
    Cell Significance Index: -0.0900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0219
    Cell Significance Index: -13.6900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0280
    Cell Significance Index: -20.5100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0364
    Cell Significance Index: -27.0000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0435
    Cell Significance Index: -2.0500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0558
    Cell Significance Index: -31.4800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0620
    Cell Significance Index: -46.9300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0818
    Cell Significance Index: -2.8800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0953
    Cell Significance Index: -12.2200
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1048
    Cell Significance Index: -7.4100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1246
    Cell Significance Index: -7.8600
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1701
    Cell Significance Index: -21.9800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1713
    Cell Significance Index: -36.0900
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.1818
    Cell Significance Index: -3.9800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1900
    Cell Significance Index: -54.6600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1908
    Cell Significance Index: -22.5000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2023
    Cell Significance Index: -29.4000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.2309
    Cell Significance Index: -23.5900
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.2563
    Cell Significance Index: -2.3600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2710
    Cell Significance Index: -20.2000
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.3057
    Cell Significance Index: -34.8900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.3138
    Cell Significance Index: -36.5800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.3468
    Cell Significance Index: -12.0500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.3501
    Cell Significance Index: -40.1100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.3782
    Cell Significance Index: -19.7000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.3811
    Cell Significance Index: -20.0100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.3957
    Cell Significance Index: -10.7700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.4068
    Cell Significance Index: -42.3600
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.4127
    Cell Significance Index: -4.9200
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.4985
    Cell Significance Index: -10.3400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.6434
    Cell Significance Index: -50.9600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.6454
    Cell Significance Index: -20.6700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.7451
    Cell Significance Index: -19.9700
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.7762
    Cell Significance Index: -16.5300
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.7774
    Cell Significance Index: -13.1000
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.7810
    Cell Significance Index: -13.0700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.7969
    Cell Significance Index: -48.8600
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.7993
    Cell Significance Index: -11.8000
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.8694
    Cell Significance Index: -22.8600
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.9192
    Cell Significance Index: -19.5100
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.9699
    Cell Significance Index: -30.8900
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.9903
    Cell Significance Index: -32.4200
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.9991
    Cell Significance Index: -14.3700
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -1.0301
    Cell Significance Index: -8.4000
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -1.0702
    Cell Significance Index: -19.7800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** TRIM33 is a member of the tripartite motif (TRIM) family of proteins, which are characterized by the presence of three distinct domains: a RING finger domain, a coiled-coil domain, and a PDZ domain. This unique structure allows TRIM33 to interact with multiple proteins and regulate various cellular processes. TRIM33 is primarily expressed in hematopoietic cells, including erythroblasts, oligopotent progenitor cells, and T cells. It is also found in non-hematopoietic cells, such as smooth muscle fibers, goblet cells, and ciliated cells. **Pathways and Functions** TRIM33 is involved in several key pathways, including: 1. **Transcriptional regulation**: TRIM33 acts as a transcriptional repressor by binding to specific DNA sequences and recruiting histone deacetylases to repress gene expression. 2. **Signaling pathways**: TRIM33 regulates various signaling pathways, including the transforming growth factor-beta (TGF-β) and BMP (bone morphogenetic protein) signaling pathways, which are crucial for cell growth, differentiation, and survival. 3. **Protein degradation**: TRIM33 acts as an E3 ubiquitin-protein ligase, which is involved in the ubiquitination and degradation of target proteins. 4. **Chromatin remodeling**: TRIM33 regulates chromatin structure and dynamics by interacting with chromatin-associated proteins and modifying histone modifications. **Clinical Significance** Dysregulation of TRIM33 has been implicated in various diseases, including: 1. **Immune disorders**: TRIM33 has been shown to play a critical role in the development and function of immune cells, including T cells and B cells. Abnormalities in TRIM33 expression or function have been linked to autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. 2. **Cancer**: TRIM33 has been implicated in the regulation of cancer cell growth, invasion, and metastasis. Mutations in TRIM33 have been found in various types of cancer, including leukemia and lymphoma. 3. **Inflammatory disorders**: TRIM33 has been shown to regulate the expression of inflammatory genes and is involved in the development of inflammatory diseases, such as atherosclerosis and inflammatory bowel disease. In conclusion, TRIM33 is a multifunctional gene that plays a critical role in regulating various cellular processes, including transcription, signaling, and protein degradation. Its dysregulation has been implicated in various diseases, highlighting the importance of understanding the function and regulation of this gene in immune cells and overall health.

Genular Protein ID: 1492625133

Symbol: TRI33_HUMAN

Name: E3 ubiquitin-protein ligase TRIM33

UniProtKB Accession Codes:

Q9UPN9 O95855 Q5TG72 Q5TG73 Q5TG74 Q9C017 Q9UJ79

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 5 CORUM 1 CTD 1 ChEBI 8 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EC 2 EMBL 7 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 13 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 11 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 9 PDBsum 9 PRINTS 1 PRO 1 PROSITE 6 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 2 RefSeq 2 SIGNOR 1 SMART 5 SMR 1 STRING 1 SUPFAM 4 SignaLink 1 TreeFam 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10022127

Title: TIF1gamma, a novel member of the transcriptional intermediary factor 1 family.

PubMed ID: 10022127

DOI: 10.1038/sj.onc.1202655

PubMed ID: 11331580

Title: The tripartite motif family identifies cell compartments.

PubMed ID: 11331580

DOI: 10.1093/emboj/20.9.2140

PubMed ID: 10470851

Title: Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10470851

DOI: 10.1093/dnares/6.3.197

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 10439047

Title: The transcription coactivator HTIF1 and a related protein are fused to the RET receptor tyrosine kinase in childhood papillary thyroid carcinomas.

PubMed ID: 10439047

DOI: 10.1038/sj.onc.1202824

PubMed ID: 12096914

Title: Hetero-oligomerization among the TIF family of RBCC/TRIM domain-containing nuclear cofactors: a potential mechanism for regulating the switch between coactivation and corepression.

PubMed ID: 12096914

DOI: 10.1016/s0022-2836(02)00477-1

PubMed ID: 15820681

Title: Germ-layer specification and control of cell growth by Ectodermin, a Smad4 ubiquitin ligase.

PubMed ID: 15820681

DOI: 10.1016/j.cell.2005.01.033

PubMed ID: 16751102

Title: Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway.

PubMed ID: 16751102

DOI: 10.1016/j.cell.2006.03.045

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19135894

Title: FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination.

PubMed ID: 19135894

DOI: 10.1016/j.cell.2008.10.051

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

DOI: 10.1038/nsmb.2890

PubMed ID: 25114211

Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.

PubMed ID: 25114211

DOI: 10.1073/pnas.1413825111

PubMed ID: 25772364

Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.

PubMed ID: 25772364

DOI: 10.1016/j.celrep.2015.02.033

PubMed ID: 25593309

Title: Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.

PubMed ID: 25593309

DOI: 10.1101/gad.252189.114

PubMed ID: 25755297

Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.

PubMed ID: 25755297

DOI: 10.1074/mcp.o114.044792

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

Sequence Information:

  • Length: 1127
  • Mass: 122533
  • Checksum: 7A36013799E9933C
  • Sequence:
    • MAENKGGGEA ESGGGGSGSA PVTAGAAGPA AQEAEPPLTA VLVEEEEEEG GRAGAEGGAA 
GPDDGGVAAA SSGSAQAASS PAASVGTGVA GGAVSTPAPA PASAPAPGPS AGPPPGPPAS 
LLDTCAVCQQ SLQSRREAEP KLLPCLHSFC LRCLPEPERQ LSVPIPGGSN GDIQQVGVIR 
CPVCRQECRQ IDLVDNYFVK DTSEAPSSSD EKSEQVCTSC EDNASAVGFC VECGEWLCKT 
CIEAHQRVKF TKDHLIRKKE DVSESVGASG QRPVFCPVHK QEQLKLFCET CDRLTCRDCQ 
LLEHKEHRYQ FLEEAFQNQK GAIENLLAKL LEKKNYVHFA ATQVQNRIKE VNETNKRVEQ 
EIKVAIFTLI NEINKKGKSL LQQLENVTKE RQMKLLQQQN DITGLSRQVK HVMNFTNWAI 
ASGSSTALLY SKRLITFQLR HILKARCDPV PAANGAIRFH CDPTFWAKNV VNLGNLVIES 
KPAPGYTPNV VVGQVPPGTN HISKTPGQIN LAQLRLQHMQ QQVYAQKHQQ LQQMRMQQPP 
APVPTTTTTT QQHPRQAAPQ MLQQQPPRLI SVQTMQRGNM NCGAFQAHQM RLAQNAARIP 
GIPRHSGPQY SMMQPHLQRQ HSNPGHAGPF PVVSVHNTTI NPTSPTTATM ANANRGPTSP 
SVTAIELIPS VTNPENLPSL PDIPPIQLED AGSSSLDNLL SRYISGSHLP PQPTSTMNPS 
PGPSALSPGS SGLSNSHTPV RPPSTSSTGS RGSCGSSGRT AEKTSLSFKS DQVKVKQEPG 
TEDEICSFSG GVKQEKTEDG RRSACMLSSP ESSLTPPLST NLHLESELDA LASLENHVKI 
EPADMNESCK QSGLSSLVNG KSPIRSLMHR SARIGGDGNN KDDDPNEDWC AVCQNGGDLL 
CCEKCPKVFH LTCHVPTLLS FPSGDWICTF CRDIGKPEVE YDCDNLQHSK KGKTAQGLSP 
VDQRKCERLL LYLYCHELSI EFQEPVPASI PNYYKIIKKP MDLSTVKKKL QKKHSQHYQI 
PDDFVADVRL IFKNCERFNE MMKVVQVYAD TQEINLKADS EVAQAGKAVA LYFEDKLTEI 
YSDRTFAPLP EFEQEEDDGE VTEDSDEDFI QPRRKRLKSD ERPVHIK

Genular Protein ID: 567044567

Symbol: B3KN30_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KN30

Database IDs:

ARBA 3 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 1 Gene3D 2 InterPro 7 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 5 PROSITE-ProRule 2 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 2 SAM 1 SMART 2 SUPFAM 2

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 759
  • Mass: 83900
  • Checksum: E7C568375BD3DC91
  • Sequence:
    • MKLLQQQNDI TGLSRQVKHV MNFTNWAIAS GSSTALLYSK RLITFQLRHI LKARCDPAPA 
ANGAIRFHCD PTFWAKNVVN LGNLVIESKP APGYTPNVVV GQVPPGTNHI SKTPGQINLA 
QLRLQHMQQQ VYAQKHQQLQ QMRMQQPPAP VPTTTTTTQQ HPRQAAPQML QQQPPRLISV 
QTMQRGNMNC GAFQAHQMRL AQNAARIPGI PRHSGPQYSM MQPHLQRQHS NPGHAGPFPV 
VSVHNTTINP TSPTTATMAN ANRGPTSPSV TAIELIPSVT NPENLPSLPD IPPIQANVVP 
MMHSWYEFGA REKTQDQNVL EDAGSSSLDN LLSRYISGSH LPPQPTSTMN PSPGPSALSP 
GSSGLSNSHT PVRPPSTSST GSRGSCGSSG RTAEKTSLSF KSDQVKVKQE PGTEDEICSF 
SGGVKQEKTE DGRRSACMLS SPESSLTPPL STNLHLESEL DALASLENHV KIEPADMNES 
CKQSGLSSLV NGKSPIRSLM HRSARIGGDG NNKDDDPNED WCAVCQNGGD LLCCEKCPKV 
FHLTCHVPTL LSFPSGDWIC TFCRDIGKPE VEYDCDNLQH SKKGKTAQGL SPVDQRKCER 
LLLYLYCHEL SIEFQEPVPA SIPNYYKIIK KPMDLSTVKK KLQKKHSQHY QIPDDFVADV 
RLIFKNCERF NEMMKVVQVY ADTQEINLKA DSEVAQAGKA VALYFEDKLT EIYSDRTFAP 
LPEFEQEEDD GEVTEDSDED FIQPRRKRLK SDERPVHIK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.