Details for: PECAM1

Gene ID: 5175

Symbol: PECAM1

Ensembl ID: ENSG00000261371

Description: platelet and endothelial cell adhesion molecule 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 64.1712
    Cell Significance Index: -26.0700
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 55.7170
    Cell Significance Index: -28.6600
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 27.7666
    Cell Significance Index: -26.5100
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 17.3399
    Cell Significance Index: -37.9500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 11.2833
    Cell Significance Index: 587.7300
  • Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
    Fold Change: 8.8647
    Cell Significance Index: 30.8400
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 8.3902
    Cell Significance Index: -25.7700
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 8.0257
    Cell Significance Index: 115.4300
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 7.8263
    Cell Significance Index: 138.3000
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 7.3615
    Cell Significance Index: 83.6300
  • Cell Name: glomerular capillary endothelial cell (CL1001005)
    Fold Change: 6.2142
    Cell Significance Index: 23.1600
  • Cell Name: endothelial cell of uterus (CL0009095)
    Fold Change: 4.7417
    Cell Significance Index: 29.6900
  • Cell Name: endocardial cell (CL0002350)
    Fold Change: 3.7838
    Cell Significance Index: 22.3400
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 3.2266
    Cell Significance Index: 49.9200
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 3.2125
    Cell Significance Index: 59.3800
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 3.1707
    Cell Significance Index: 32.8400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 2.3191
    Cell Significance Index: 142.1800
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 2.2543
    Cell Significance Index: 16.1900
  • Cell Name: pulmonary capillary endothelial cell (CL4028001)
    Fold Change: 2.1894
    Cell Significance Index: 29.9800
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.8342
    Cell Significance Index: 5.0400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.7678
    Cell Significance Index: 34.8000
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: 0.6596
    Cell Significance Index: 6.2700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.5483
    Cell Significance Index: 104.3400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3758
    Cell Significance Index: 339.3600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.3305
    Cell Significance Index: 32.6900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.2493
    Cell Significance Index: 29.0500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.2463
    Cell Significance Index: 48.8900
  • Cell Name: vein endothelial cell of respiratory system (CL4033008)
    Fold Change: 0.2050
    Cell Significance Index: 1.3200
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.1000
    Cell Significance Index: 16.2600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 0.0490
    Cell Significance Index: 30.6200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0440
    Cell Significance Index: 30.4200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0132
    Cell Significance Index: 2.6500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0048
    Cell Significance Index: 0.1100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0043
    Cell Significance Index: -3.1700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0048
    Cell Significance Index: -0.1700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0064
    Cell Significance Index: -11.9800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0065
    Cell Significance Index: -3.6400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0153
    Cell Significance Index: -28.2100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0170
    Cell Significance Index: -9.2600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0171
    Cell Significance Index: -26.2700
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0220
    Cell Significance Index: -29.8700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0232
    Cell Significance Index: -17.5700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0271
    Cell Significance Index: -0.7800
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0290
    Cell Significance Index: -0.7400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0295
    Cell Significance Index: -6.2200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0312
    Cell Significance Index: -0.7800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0339
    Cell Significance Index: -12.1500
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.0368
    Cell Significance Index: -4.0000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0385
    Cell Significance Index: -28.2400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0399
    Cell Significance Index: -25.3400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0558
    Cell Significance Index: -25.3200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0600
    Cell Significance Index: -10.8300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0625
    Cell Significance Index: -10.6800
  • Cell Name: late promyelocyte (CL0002151)
    Fold Change: -0.0693
    Cell Significance Index: -0.4600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0714
    Cell Significance Index: -7.2900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0820
    Cell Significance Index: -9.3900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0887
    Cell Significance Index: -25.5200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.1000
    Cell Significance Index: -12.3000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1109
    Cell Significance Index: -8.5100
  • Cell Name: blood vessel endothelial cell (CL0000071)
    Fold Change: -0.1289
    Cell Significance Index: -1.4000
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.1384
    Cell Significance Index: -6.0200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1493
    Cell Significance Index: -21.7000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.1515
    Cell Significance Index: -20.8100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.1716
    Cell Significance Index: -11.8700
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.1850
    Cell Significance Index: -21.1200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1895
    Cell Significance Index: -24.4800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1919
    Cell Significance Index: -22.6300
  • Cell Name: early promyelocyte (CL0002154)
    Fold Change: -0.2005
    Cell Significance Index: -1.2800
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: -0.2147
    Cell Significance Index: -1.7000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2210
    Cell Significance Index: -23.0200
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: -0.2279
    Cell Significance Index: -3.1300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.2362
    Cell Significance Index: -30.2800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.3132
    Cell Significance Index: -23.3400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.3511
    Cell Significance Index: -22.6500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3562
    Cell Significance Index: -28.2100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.3621
    Cell Significance Index: -24.3500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.3695
    Cell Significance Index: -17.3700
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.3745
    Cell Significance Index: -22.4800
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.3816
    Cell Significance Index: -4.6900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.3894
    Cell Significance Index: -24.5400
  • Cell Name: vein endothelial cell (CL0002543)
    Fold Change: -0.3952
    Cell Significance Index: -4.2900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.4006
    Cell Significance Index: -22.4800
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.4099
    Cell Significance Index: -10.9700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.4220
    Cell Significance Index: -25.9400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.4831
    Cell Significance Index: -25.3700
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.4941
    Cell Significance Index: -15.8300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.4956
    Cell Significance Index: -21.9200
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.5029
    Cell Significance Index: -16.4700
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.5069
    Cell Significance Index: -11.1000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.5092
    Cell Significance Index: -26.4500
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.5192
    Cell Significance Index: -18.1900
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: -0.5193
    Cell Significance Index: -7.5400
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: -0.5266
    Cell Significance Index: -4.6400
  • Cell Name: endothelial cell of artery (CL1000413)
    Fold Change: -0.5465
    Cell Significance Index: -5.7600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.5564
    Cell Significance Index: -25.9400
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.5786
    Cell Significance Index: -21.9100
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.5864
    Cell Significance Index: -18.6800
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.5938
    Cell Significance Index: -11.6100
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.6438
    Cell Significance Index: -9.2200
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.6541
    Cell Significance Index: -11.2100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** PECAM1 is a 110-kDa protein composed of four extracellular Ig-like domains and a cytoplasmic tail. It is a homophilic adhesion molecule, meaning it binds to itself, and is involved in mediating cell-cell adhesion, particularly in the context of tight junctions and adherens junctions. PECAM1 is also a signaling molecule, capable of triggering various downstream pathways, including those involved in cell migration, proliferation, and survival. Its expression is tightly regulated, with PECAM1 being upregulated in response to inflammatory stimuli and downregulated in certain pathological conditions. **Pathways and Functions** PECAM1 is involved in several key cellular processes, including: 1. **Cell-cell adhesion**: PECAM1 mediates adhesion between endothelial cells, platelets, and immune cells, facilitating their interaction and communication. 2. **Cell migration**: PECAM1 is a key regulator of cell migration, particularly in the context of immune responses, where it facilitates the movement of leukocytes across the endothelium. 3. **Inflammation**: PECAM1 is upregulated in response to inflammatory stimuli, promoting the recruitment and activation of immune cells. 4. **Angiogenesis**: PECAM1 plays a role in the regulation of angiogenesis, the process of new blood vessel formation. 5. **Blood-brain barrier maintenance**: PECAM1 is essential for maintaining the integrity of the blood-brain barrier, preventing the infiltration of immune cells and toxins. **Clinical Significance** PECAM1 is implicated in various diseases, including: 1. **Thrombotic disorders**: PECAM1 is involved in platelet activation and aggregation, contributing to the development of thrombotic disorders, such as deep vein thrombosis and pulmonary embolism. 2. **Inflammatory disorders**: PECAM1 is upregulated in response to inflammatory stimuli, contributing to the pathogenesis of inflammatory disorders, such as atherosclerosis and rheumatoid arthritis. 3. **Cancer**: PECAM1 is involved in tumor cell metastasis and angiogenesis, highlighting its potential as a therapeutic target in cancer therapy. 4. **Neurological disorders**: PECAM1 is implicated in the pathogenesis of neurological disorders, such as multiple sclerosis and stroke, where it regulates the integrity of the blood-brain barrier. In conclusion, PECAM1 is a multifunctional protein that plays a crucial role in maintaining vascular integrity, regulating immune responses, and contributing to the pathogenesis of various diseases. Further research is necessary to fully elucidate the mechanisms by which PECAM1 regulates cellular processes and to explore its therapeutic potential in the treatment of human diseases.

Genular Protein ID: 2158558067

Symbol: PECA1_HUMAN

Name: Platelet endothelial cell adhesion molecule

UniProtKB Accession Codes:

P16284 A0A075B738 A8K3S7 D3DU31 Q6LDA9 Q8TBH1 Q96RF5 Q96RF6 Q9NP65 Q9NPB7 Q9NPG9 Q9NQS9 Q9NQT0 Q9NQT1 Q9NQT2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CPTAC 3 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 42 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 31 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 3 PDBsum 3 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 6 Pumba 1 RNAct 1 Reactome 6 RefSeq 9 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TopDownProteomics 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2351935

Title: Molecular cloning of CD31, a putative intercellular adhesion molecule closely related to carcinoembryonic antigen.

PubMed ID: 2351935

DOI: 10.1084/jem.171.6.2147

PubMed ID: 1700999

Title: Molecular characterization and functional analysis of the leukocyte surface protein CD31.

PubMed ID: 1700999

PubMed ID: 1690453

Title: PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily.

PubMed ID: 1690453

DOI: 10.1126/science.1690453

PubMed ID: 1874786

Title: Molecular and cellular properties of PECAM-1 (endoCAM/CD31): a novel vascular cell-cell adhesion molecule.

PubMed ID: 1874786

DOI: 10.1083/jcb.114.5.1059

PubMed ID: 7994021

Title: Organization of the gene for human platelet/endothelial cell adhesion molecule-1 shows alternatively spliced isoforms and a functionally complex cytoplasmic domain.

PubMed ID: 7994021

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17212705

Title: CD31/PECAM-1 genotyping and haplotype analyses show population diversity.

PubMed ID: 17212705

DOI: 10.1111/j.1399-0039.2006.00722.x

PubMed ID: 8226797

Title: Identification of PECAM-1 in solid tumor cells and its potential involvement in tumor cell adhesion to endothelium.

PubMed ID: 8226797

DOI: 10.1016/s0021-9258(18)41609-2

PubMed ID: 9298995

Title: Tyrosine residue in exon 14 of the cytoplasmic domain of platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31) regulates ligand binding specificity.

PubMed ID: 9298995

DOI: 10.1083/jcb.138.6.1425

PubMed ID: 12110892

Title: Apoptosis disables CD31-mediated cell detachment from phagocytes promoting binding and engulfment.

PubMed ID: 12110892

DOI: 10.1038/nature00811

PubMed ID: 12433657

Title: Tissue-specific distributions of alternatively spliced human PECAM-1 isoforms.

PubMed ID: 12433657

DOI: 10.1152/ajpheart.00600.2002

PubMed ID: 17139370

Title: Palmitoylation at Cys595 is essential for PECAM-1 localisation into membrane microdomains and for efficient PECAM-1-mediated cytoprotection.

PubMed ID: 17139370

DOI: 10.1160/th06-08-0459

PubMed ID: 17580308

Title: The neutrophil-specific antigen CD177 is a counter-receptor for platelet endothelial cell adhesion molecule-1 (CD31).

PubMed ID: 17580308

DOI: 10.1074/jbc.m701120200

PubMed ID: 18672896

Title: Regulation of G protein-coupled receptor activities by the platelet-endothelial cell adhesion molecule, PECAM-1.

PubMed ID: 18672896

DOI: 10.1021/bi8003846

PubMed ID: 18710921

Title: Mechanotransduction in an extracted cell model: Fyn drives stretch- and flow-elicited PECAM-1 phosphorylation.

PubMed ID: 18710921

DOI: 10.1083/jcb.200801062

PubMed ID: 18388311

Title: An alternatively spliced isoform of PECAM-1 is expressed at high levels in human and murine tissues, and suggests a novel role for the C-terminus of PECAM-1 in cytoprotective signaling.

PubMed ID: 18388311

DOI: 10.1242/jcs.025163

PubMed ID: 18088087

Title: Phosphoproteome of resting human platelets.

PubMed ID: 18088087

DOI: 10.1021/pr0704130

PubMed ID: 19342684

Title: A novel and critical role for tyrosine 663 in platelet endothelial cell adhesion molecule-1 trafficking and transendothelial migration.

PubMed ID: 19342684

DOI: 10.4049/jimmunol.0803192

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 19349973

Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.

PubMed ID: 19349973

DOI: 10.1038/nbt.1532

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 22496122

Title: Endothelial cell palmitoylproteomic identifies novel lipid-modified targets and potential substrates for protein acyl transferases.

PubMed ID: 22496122

DOI: 10.1161/circresaha.112.269514

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 21464369

Title: Residues within a lipid-associated segment of the PECAM-1 cytoplasmic domain are susceptible to inducible, sequential phosphorylation.

PubMed ID: 21464369

DOI: 10.1182/blood-2010-11-317867

PubMed ID: 26702061

Title: Structural basis for PECAM-1 homophilic binding.

PubMed ID: 26702061

DOI: 10.1182/blood-2015-07-660092

PubMed ID: 27958302

Title: Structural basis for human PECAM-1-mediated trans-homophilic cell adhesion.

PubMed ID: 27958302

DOI: 10.1038/srep38655

PubMed ID: 8532023

Title: Polymorphism of adhesion molecule CD31 and its role in acute graft-versus-host disease.

PubMed ID: 8532023

DOI: 10.1056/nejm199602013340502

PubMed ID: 11791967

Title: Codon 125 polymorphism of CD31 and susceptibility to malaria.

PubMed ID: 11791967

DOI: 10.4269/ajtmh.2001.65.736

Sequence Information:

  • Length: 738
  • Mass: 82522
  • Checksum: 9D531D2DDCCB7F92
  • Sequence:
    • MQPRWAQGAT MWLGVLLTLL LCSSLEGQEN SFTINSVDMK SLPDWTVQNG KNLTLQCFAD 
VSTTSHVKPQ HQMLFYKDDV LFYNISSMKS TESYFIPEVR IYDSGTYKCT VIVNNKEKTT 
AEYQVLVEGV PSPRVTLDKK EAIQGGIVRV NCSVPEEKAP IHFTIEKLEL NEKMVKLKRE 
KNSRDQNFVI LEFPVEEQDR VLSFRCQARI ISGIHMQTSE STKSELVTVT ESFSTPKFHI 
SPTGMIMEGA QLHIKCTIQV THLAQEFPEI IIQKDKAIVA HNRHGNKAVY SVMAMVEHSG 
NYTCKVESSR ISKVSSIVVN ITELFSKPEL ESSFTHLDQG ERLNLSCSIP GAPPANFTIQ 
KEDTIVSQTQ DFTKIASKSD SGTYICTAGI DKVVKKSNTV QIVVCEMLSQ PRISYDAQFE 
VIKGQTIEVR CESISGTLPI SYQLLKTSKV LENSTKNSND PAVFKDNPTE DVEYQCVADN 
CHSHAKMLSE VLRVKVIAPV DEVQISILSS KVVESGEDIV LQCAVNEGSG PITYKFYREK 
EGKPFYQMTS NATQAFWTKQ KASKEQEGEY YCTAFNRANH ASSVPRSKIL TVRVILAPWK 
KGLIAVVIIG VIIALLIIAA KCYFLRKAKA KQMPVEMSRP AVPLLNSNNE KMSDPNMEAN 
SHYGHNDDVR NHAMKPINDN KEPLNSDVQY TEVQVSSAES HKDLGKKDTE TVYSEVRKAV 
PDAVESRYSR TEGSLDGT

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.