Details for: PER1

Gene ID: 5187

Symbol: PER1

Ensembl ID: ENSG00000179094

Description: period circadian regulator 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 257.8350
    Cell Significance Index: -40.1100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 150.8811
    Cell Significance Index: -38.2700
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 88.8108
    Cell Significance Index: -36.0800
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 88.4304
    Cell Significance Index: -41.7500
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 78.6764
    Cell Significance Index: -40.4700
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 37.8531
    Cell Significance Index: -36.1400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 33.2494
    Cell Significance Index: -41.0000
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 15.1594
    Cell Significance Index: -40.6100
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 10.9362
    Cell Significance Index: -33.5900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 10.5979
    Cell Significance Index: -41.8200
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 7.7082
    Cell Significance Index: -16.8700
  • Cell Name: epidermal cell (CL0000362)
    Fold Change: 3.1715
    Cell Significance Index: 7.1500
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 3.0787
    Cell Significance Index: 20.8600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.5377
    Cell Significance Index: 44.0800
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.4800
    Cell Significance Index: 146.4000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.2008
    Cell Significance Index: 92.1500
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 1.0312
    Cell Significance Index: 25.1600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.9144
    Cell Significance Index: 19.8100
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.8332
    Cell Significance Index: 22.3300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.8144
    Cell Significance Index: 22.7600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.8030
    Cell Significance Index: 161.0800
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.7368
    Cell Significance Index: 80.1400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.6998
    Cell Significance Index: 32.8900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.6550
    Cell Significance Index: 42.2600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.6052
    Cell Significance Index: 27.4300
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.4821
    Cell Significance Index: 8.9100
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.4816
    Cell Significance Index: 28.9100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.4721
    Cell Significance Index: 22.0100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.4599
    Cell Significance Index: 203.3300
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: 0.4543
    Cell Significance Index: 6.9000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.4371
    Cell Significance Index: 12.6000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.4195
    Cell Significance Index: 789.9100
  • Cell Name: type II muscle cell (CL0002212)
    Fold Change: 0.3861
    Cell Significance Index: 6.2300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3722
    Cell Significance Index: 25.7400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.3468
    Cell Significance Index: 9.4400
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: 0.3027
    Cell Significance Index: 34.5500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.2979
    Cell Significance Index: 106.8500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.2452
    Cell Significance Index: 12.7400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.2294
    Cell Significance Index: 29.4100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1859
    Cell Significance Index: 25.5400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1744
    Cell Significance Index: 21.4500
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1735
    Cell Significance Index: 33.0100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.1635
    Cell Significance Index: 21.1300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.1489
    Cell Significance Index: 202.4100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.1447
    Cell Significance Index: 91.9200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.1401
    Cell Significance Index: 23.9200
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.1379
    Cell Significance Index: 10.2800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.1332
    Cell Significance Index: 245.7400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1288
    Cell Significance Index: 89.0600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.1009
    Cell Significance Index: 155.3500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0952
    Cell Significance Index: 17.1600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0902
    Cell Significance Index: 3.1700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0778
    Cell Significance Index: 42.4800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0612
    Cell Significance Index: 27.7700
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0567
    Cell Significance Index: 4.0100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0387
    Cell Significance Index: 7.6800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.0246
    Cell Significance Index: 22.1700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.0011
    Cell Significance Index: 0.1100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0114
    Cell Significance Index: -8.6500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0132
    Cell Significance Index: -9.8000
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.0142
    Cell Significance Index: -0.3800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0145
    Cell Significance Index: -9.0500
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.0188
    Cell Significance Index: -0.2700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0222
    Cell Significance Index: -16.2600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0351
    Cell Significance Index: -19.7800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0879
    Cell Significance Index: -10.3700
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.1102
    Cell Significance Index: -2.1500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1167
    Cell Significance Index: -24.5900
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: -0.1172
    Cell Significance Index: -0.5100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1176
    Cell Significance Index: -17.1000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1255
    Cell Significance Index: -36.1200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1478
    Cell Significance Index: -17.2200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1767
    Cell Significance Index: -18.4000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2042
    Cell Significance Index: -23.4000
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.2336
    Cell Significance Index: -3.9400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.3094
    Cell Significance Index: -6.5900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.3301
    Cell Significance Index: -17.3300
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.3434
    Cell Significance Index: -17.3500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.3484
    Cell Significance Index: -19.5500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.3562
    Cell Significance Index: -4.8600
  • Cell Name: seromucus secreting cell (CL0000159)
    Fold Change: -0.3769
    Cell Significance Index: -7.8600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.3790
    Cell Significance Index: -23.8900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.4000
    Cell Significance Index: -17.7000
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.4274
    Cell Significance Index: -6.3100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4343
    Cell Significance Index: -34.4000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.4658
    Cell Significance Index: -14.9200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4914
    Cell Significance Index: -30.1300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.5269
    Cell Significance Index: -14.0700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.5416
    Cell Significance Index: -33.2900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.5665
    Cell Significance Index: -14.1600
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.5688
    Cell Significance Index: -8.4000
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: -0.5811
    Cell Significance Index: -8.8400
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.5816
    Cell Significance Index: -14.9500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.6028
    Cell Significance Index: -31.4000
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.6080
    Cell Significance Index: -23.0300
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.6406
    Cell Significance Index: -11.3200
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.6470
    Cell Significance Index: -9.7000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.6536
    Cell Significance Index: -43.9500
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.6951
    Cell Significance Index: -16.0600
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.7239
    Cell Significance Index: -19.0400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** The PER1 gene is characterized by its expression in various tissues, including the eye, kidney, and skeletal muscle. It is also highly expressed in cells that are sensitive to light, such as photoreceptors in the retina. PER1 is a negative regulator of the circadian clock, meaning it helps to slow down the clock in response to light exposure. This function is critical for maintaining the body's internal clock in synchrony with the external environment. Additionally, PER1 has been shown to interact with various transcription factors, including E-box-binding proteins and glucocorticoid receptor, to regulate gene expression. **Pathways and Functions** PER1 is involved in several key pathways, including: 1. **Circadian clock regulation**: PER1 plays a critical role in the negative regulation of the circadian clock, helping to reset the clock in response to changes in light and darkness. 2. **Transcriptional regulation**: PER1 influences the expression of numerous genes involved in various cellular processes, including inflammation, hair growth, and ion transport. 3. **DNA-binding transcription factor binding**: PER1 interacts with various transcription factors, including E-box-binding proteins and glucocorticoid receptor, to regulate gene expression. 4. **Chromatin remodeling**: PER1 has been shown to influence chromatin structure and remodeling, which is essential for gene regulation. The functions of PER1 include: 1. **Regulation of circadian rhythm**: PER1 helps to maintain the body's internal clock in synchrony with the external environment. 2. **Negative regulation of NF-κB signaling**: PER1 inhibits the activity of NF-κB, a transcription factor involved in inflammation and immune responses. 3. **Regulation of cytokine production**: PER1 influences the production of cytokines, which are signaling molecules involved in immune responses. 4. **Regulation of hair cycle**: PER1 has been shown to influence the growth and maintenance of hair. **Clinical Significance** Dysregulation of the PER1 gene has been implicated in various diseases, including: 1. **Circadian rhythm disorders**: PER1 mutations have been linked to circadian rhythm disorders, such as delayed sleep phase syndrome. 2. **Cancer**: PER1 has been shown to influence cancer cell proliferation and survival. 3. **Neurodegenerative diseases**: PER1 has been implicated in the pathogenesis of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. 4. **Metabolic disorders**: PER1 has been shown to influence glucose metabolism and insulin sensitivity. In conclusion, the PER1 gene plays a critical role in regulating the mammalian circadian clock and influencing various cellular processes, including inflammation, hair growth, and ion transport. Dysregulation of PER1 has been implicated in various diseases, highlighting the importance of this gene in maintaining human health.

Genular Protein ID: 1723433107

Symbol: PER1_HUMAN

Name: Period circadian protein homolog 1

UniProtKB Accession Codes:

O15534 B2RPA8 B4DI49 D3DTR3

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChiTaRS 1 ComplexPortal 2 DIP 1 DNASU 1 DisGeNET 1 EMBL 10 Ensembl 2 ExpressionAtlas 1 GO 31 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 2 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9323128

Title: Rigui, a putative mammalian ortholog of the Drosophila period gene.

PubMed ID: 9323128

DOI: 10.1016/s0092-8674(00)80366-9

PubMed ID: 9333243

Title: Circadian oscillation of a mammalian homologue of the Drosophila period gene.

PubMed ID: 9333243

DOI: 10.1038/39086

PubMed ID: 10940553

Title: The human Per1 gene: genomic organization and promoter analysis of the first human orthologue of the Drosophila period gene.

PubMed ID: 10940553

DOI: 10.1016/s0378-1119(00)00248-1

PubMed ID: 10857746

Title: The human and mouse Period1 genes: five well-conserved E-boxes additively contribute to the enhancement of mPer1 transcription.

PubMed ID: 10857746

DOI: 10.1006/geno.2000.6166

PubMed ID: 9455484

Title: Characterization of cDNA clones in size-fractionated cDNA libraries from human brain.

PubMed ID: 9455484

DOI: 10.1093/dnares/4.5.345

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9427249

Title: Two period homologs: circadian expression and photic regulation in the suprachiasmatic nuclei.

PubMed ID: 9427249

DOI: 10.1016/s0896-6273(00)80417-1

PubMed ID: 10790862

Title: Phosphorylation and destabilization of human period I clock protein by human casein kinase I epsilon.

PubMed ID: 10790862

DOI: 10.1097/00001756-200004070-00011

PubMed ID: 11165242

Title: Human casein kinase Idelta phosphorylation of human circadian clock proteins period 1 and 2.

PubMed ID: 11165242

DOI: 10.1016/s0014-5793(00)02434-0

PubMed ID: 14750904

Title: Phosphorylation of clock protein PER1 regulates its circadian degradation in normal human fibroblasts.

PubMed ID: 14750904

DOI: 10.1042/bj20031308

PubMed ID: 15917222

Title: SCFbeta-TRCP controls clock-dependent transcription via casein kinase 1-dependent degradation of the mammalian period-1 (Per1) protein.

PubMed ID: 15917222

DOI: 10.1074/jbc.m502862200

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 23303907

Title: Metabolism and the circadian clock converge.

PubMed ID: 23303907

DOI: 10.1152/physrev.00016.2012

PubMed ID: 24005054

Title: A meeting of two chronobiological systems: circadian proteins Period1 and BMAL1 modulate the human hair cycle clock.

PubMed ID: 24005054

DOI: 10.1038/jid.2013.366

PubMed ID: 23916625

Title: Molecular architecture of the mammalian circadian clock.

PubMed ID: 23916625

DOI: 10.1016/j.tcb.2013.07.002

PubMed ID: 30530698

Title: Nuclear receptor HNF4A transrepresses CLOCK:BMAL1 and modulates tissue-specific circadian networks.

PubMed ID: 30530698

DOI: 10.1073/pnas.1816411115

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

PubMed ID: 27717682

Title: Exome sequencing identified CCER2 as a novel candidate gene for Moyamoya disease.

PubMed ID: 27717682

DOI: 10.1016/j.jstrokecerebrovasdis.2016.09.003

Sequence Information:

  • Length: 1290
  • Mass: 136212
  • Checksum: 60B844468EEF4D1B
  • Sequence:
    • MSGPLEGADG GGDPRPGESF CPGGVPSPGP PQHRPCPGPS LADDTDANSN GSSGNESNGH 
ESRGASQRSS HSSSSGNGKD SALLETTESS KSTNSQSPSP PSSSIAYSLL SASSEQDNPS 
TSGCSSEQSA RARTQKELMT ALRELKLRLP PERRGKGRSG TLATLQYALA CVKQVQANQE 
YYQQWSLEEG EPCSMDMSTY TLEELEHITS EYTLQNQDTF SVAVSFLTGR IVYISEQAAV 
LLRCKRDVFR GTRFSELLAP QDVGVFYGST APSRLPTWGT GASAGSGLRD FTQEKSVFCR 
IRGGPDRDPG PRYQPFRLTP YVTKIRVSDG APAQPCCLLI AERIHSGYEA PRIPPDKRIF 
TTRHTPSCLF QDVDERAAPL LGYLPQDLLG APVLLFLHPE DRPLMLAIHK KILQLAGQPF 
DHSPIRFCAR NGEYVTMDTS WAGFVHPWSR KVAFVLGRHK VRTAPLNEDV FTPPAPSPAP 
SLDTDIQELS EQIHRLLLQP VHSPSPTGLC GVGAVTSPGP LHSPGSSSDS NGGDAEGPGP 
PAPVTFQQIC KDVHLVKHQG QQLFIESRAR PQSRPRLPAT GTFKAKALPC QSPDPELEAG 
SAPVQAPLAL VPEEAERKEA SSCSYQQINC LDSILRYLES CNLPSTTKRK CASSSSYTTS 
SASDDDRQRT GPVSVGTKKD PPSAALSGEG ATPRKEPVVG GTLSPLALAN KAESVVSVTS 
QCSFSSTIVH VGDKKPPESD IIMMEDLPGL APGPAPSPAP SPTVAPDPAP DAYRPVGLTK 
AVLSLHTQKE EQAFLSRFRD LGRLRGLDSS STAPSALGER GCHHGPAPPS RRHHCRSKAK 
RSRHHQNPRA EAPCYVSHPS PVPPSTPWPT PPATTPFPAV VQPYPLPVFS PRGGPQPLPP 
APTSVPPAAF PAPLVTPMVA LVLPNYLFPT PSSYPYGALQ TPAEGPPTPA SHSPSPSLPA 
LAPSPPHRPD SPLFNSRCSS PLQLNLLQLE ELPRAEGAAV AGGPGSSAGP PPPSAEAAEP 
EARLAEVTES SNQDALSGSS DLLELLLQED SRSGTGSAAS GSLGSGLGSG SGSGSHEGGS 
TSASITRSSQ SSHTSKYFGS IDSSEAEAGA ARGGAEPGDQ VIKYVLQDPI WLLMANADQR 
VMMTYQVPSR DMTSVLKQDR ERLRAMQKQQ PRFSEDQRRE LGAVHSWVRK GQLPRALDVM 
ACVDCGSSTQ DPGHPDDPLF SELDGLGLEP MEEGGGEQGS SGGGSGEGEG CEEAQGGAKA 
SSSQDLAMEE EEEGRSSSSP ALPTAGNCTS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.