Details for: PIK3R2

Gene ID: 5296

Symbol: PIK3R2

Ensembl ID: ENSG00000105647

Description: phosphoinositide-3-kinase regulatory subunit 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 72.9048
    Cell Significance Index: -11.3400
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 48.6904
    Cell Significance Index: -12.3500
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 24.9103
    Cell Significance Index: -10.1200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 9.9355
    Cell Significance Index: -12.2500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 4.5728
    Cell Significance Index: -12.2500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.5301
    Cell Significance Index: 91.8600
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.3115
    Cell Significance Index: 18.6700
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.7659
    Cell Significance Index: 83.3100
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.6505
    Cell Significance Index: 5.9900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.6212
    Cell Significance Index: 124.6200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.5820
    Cell Significance Index: 104.9200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.5608
    Cell Significance Index: 68.9600
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.4233
    Cell Significance Index: 9.7800
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4019
    Cell Significance Index: 39.7600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.3923
    Cell Significance Index: 24.1100
  • Cell Name: pancreatic epsilon cell (CL0005019)
    Fold Change: 0.3745
    Cell Significance Index: 3.4700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3543
    Cell Significance Index: 24.5000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.3294
    Cell Significance Index: 118.1600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3093
    Cell Significance Index: 279.3100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.2824
    Cell Significance Index: 7.0600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.2736
    Cell Significance Index: 12.4000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.2590
    Cell Significance Index: 42.1300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.2037
    Cell Significance Index: 15.6400
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.1944
    Cell Significance Index: 2.8700
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.1830
    Cell Significance Index: 4.3900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.1728
    Cell Significance Index: 20.1400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.1350
    Cell Significance Index: 3.8900
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: 0.1334
    Cell Significance Index: 15.2300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.1147
    Cell Significance Index: 14.7000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.1066
    Cell Significance Index: 2.3100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1064
    Cell Significance Index: 20.2400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.0950
    Cell Significance Index: 5.3300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0777
    Cell Significance Index: 4.9000
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.0551
    Cell Significance Index: 2.7800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0403
    Cell Significance Index: 5.5400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.0296
    Cell Significance Index: 1.3100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0118
    Cell Significance Index: 6.4700
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.0088
    Cell Significance Index: 0.1200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0075
    Cell Significance Index: 0.1600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.0059
    Cell Significance Index: 0.2300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0033
    Cell Significance Index: 1.4800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0046
    Cell Significance Index: -2.8800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0066
    Cell Significance Index: -1.1200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0074
    Cell Significance Index: -13.6100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0076
    Cell Significance Index: -5.6200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0087
    Cell Significance Index: -13.4700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0130
    Cell Significance Index: -9.8400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0133
    Cell Significance Index: -7.4900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0137
    Cell Significance Index: -10.0500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0142
    Cell Significance Index: -0.7400
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0193
    Cell Significance Index: -0.8400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0222
    Cell Significance Index: -0.7800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0334
    Cell Significance Index: -7.0300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0400
    Cell Significance Index: -4.5800
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -0.0604
    Cell Significance Index: -0.7700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0626
    Cell Significance Index: -12.4200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0638
    Cell Significance Index: -8.2400
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.0676
    Cell Significance Index: -0.7000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0710
    Cell Significance Index: -10.3200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0773
    Cell Significance Index: -2.0700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0801
    Cell Significance Index: -4.9100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0836
    Cell Significance Index: -8.5400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0856
    Cell Significance Index: -2.3300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0982
    Cell Significance Index: -4.5800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1034
    Cell Significance Index: -7.7100
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.1065
    Cell Significance Index: -2.2100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1069
    Cell Significance Index: -12.6100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1180
    Cell Significance Index: -3.7800
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.1235
    Cell Significance Index: -1.0500
  • Cell Name: oral mucosa squamous cell (CL1001576)
    Fold Change: -0.1268
    Cell Significance Index: -1.0900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1328
    Cell Significance Index: -9.3900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1360
    Cell Significance Index: -6.3900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1383
    Cell Significance Index: -10.9500
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1418
    Cell Significance Index: -2.0300
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: -0.1609
    Cell Significance Index: -2.1700
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1625
    Cell Significance Index: -2.7200
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.1637
    Cell Significance Index: -6.7100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1659
    Cell Significance Index: -10.7000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1663
    Cell Significance Index: -8.7300
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.1667
    Cell Significance Index: -4.7800
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1709
    Cell Significance Index: -8.9000
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1755
    Cell Significance Index: -5.5900
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.1787
    Cell Significance Index: -3.8600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1823
    Cell Significance Index: -5.9700
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: -0.1917
    Cell Significance Index: -2.1700
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1967
    Cell Significance Index: -4.1800
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.1967
    Cell Significance Index: -3.9500
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2175
    Cell Significance Index: -7.6200
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.2185
    Cell Significance Index: -4.3200
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.2235
    Cell Significance Index: -3.8700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.2584
    Cell Significance Index: -8.9800
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.2598
    Cell Significance Index: -2.8300
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.2702
    Cell Significance Index: -5.6400
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.2706
    Cell Significance Index: -2.5700
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.2734
    Cell Significance Index: -6.8200
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: -0.2770
    Cell Significance Index: -3.9700
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.2783
    Cell Significance Index: -4.6800
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.2866
    Cell Significance Index: -10.5200
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.2927
    Cell Significance Index: -3.6300
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: -0.3306
    Cell Significance Index: -4.6400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** PIK3R2 is a member of the phosphoinositide 3-kinase regulatory subunit family, which is composed of four isoforms (PIK3R1, PIK3R2, PIK3R3, and PIK3R4). PIK3R2 is unique in that it contains a C-terminal extension that is not found in other PI3K regulatory subunits. This extension is thought to play a role in the regulation of PI3K activity and the recruitment of downstream effectors. PIK3R2 is also highly phosphorylated, which may regulate its interactions with other proteins and influence its signaling activity. **Pathways and Functions** PIK3R2 is involved in a wide range of signaling pathways, including: 1. **PI3K/Akt signaling pathway**: PIK3R2 is essential for the activation of the PI3K/Akt signaling pathway, which regulates cell growth, differentiation, and survival. 2. **Adaptive immune system**: PIK3R2 is highly expressed in immune cells, where it plays a role in the regulation of immune responses, including T-cell activation and proliferation. 3. **Neuronal development**: PIK3R2 is expressed in neurons and plays a role in the regulation of neuronal development and function. 4. **Angiogenesis**: PIK3R2 is involved in the regulation of angiogenesis, the process of new blood vessel formation. **Clinical Significance** Dysregulation of the PI3K/Akt signaling pathway, including PIK3R2, has been implicated in various diseases, including: 1. **Cancer**: PIK3R2 is overexpressed in many types of cancer, where it contributes to tumorigenesis and resistance to therapy. 2. **Immunodeficiency**: PIK3R2 deficiency has been associated with impaired immune function and increased susceptibility to infections. 3. **Neurodegenerative diseases**: PIK3R2 has been implicated in the pathogenesis of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. 4. **Cardiovascular disease**: PIK3R2 has been linked to cardiovascular disease, including hypertension and atherosclerosis. In conclusion, PIK3R2 is a critical component of the PI3K/Akt signaling pathway, which plays a vital role in various cellular processes, including immune responses, neuronal development, and angiogenesis. Dysregulation of PIK3R2 has been implicated in various diseases, highlighting the need for further research into the mechanisms of PIK3R2 function and its role in disease pathology.

Genular Protein ID: 807882482

Symbol: P85B_HUMAN

Name: Phosphatidylinositol 3-kinase regulatory subunit beta

UniProtKB Accession Codes:

O00459 Q5EAT5 Q9UPH9

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 BRENDA 1 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 4 CPTAC 3 CTD 1 ChEMBL 1 ChiTaRS 1 ComplexPortal 3 DIP 1 DNASU 1 DisGeNET 1 DrugBank 1 EMBL 4 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 29 Gene3D 4 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 10 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 2 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 8 PDBsum 8 PIR 1 PRINTS 2 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 47 RefSeq 1 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1314371

Title: Chromosomal localization of human p85 alpha, a subunit of phosphatidylinositol 3-kinase, and its homologue p85 beta.

PubMed ID: 1314371

PubMed ID: 9582025

Title: An oncogenic fusion product of the phosphatidylinositol 3-kinase p85beta subunit and HUMORF8, a putative deubiquitinating enzyme.

PubMed ID: 9582025

DOI: 10.1038/sj.onc.1201695

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9178760

Title: Intracellular signaling of the Ufo/Axl receptor tyrosine kinase is mediated mainly by a multi-substrate docking-site.

PubMed ID: 9178760

DOI: 10.1038/sj.onc.1201123

PubMed ID: 9600074

Title: Tyrosine 1213 of Flt-1 is a major binding site of Nck and SHP-2.

PubMed ID: 9600074

DOI: 10.1006/bbrc.1998.8578

PubMed ID: 15102829

Title: Activation of vascular endothelial growth factor receptor-3 and its downstream signaling promote cell survival under oxidative stress.

PubMed ID: 15102829

DOI: 10.1074/jbc.m314015200

PubMed ID: 18348712

Title: The tyrosine phosphatase CD148 interacts with the p85 regulatory subunit of phosphoinositide 3-kinase.

PubMed ID: 18348712

DOI: 10.1042/bj20071317

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 23604317

Title: FBXL2- and PTPL1-mediated degradation of p110-free p85beta regulatory subunit controls the PI(3)K signalling cascade.

PubMed ID: 23604317

DOI: 10.1038/ncb2731

PubMed ID: 23745724

Title: AKT3 and PIK3R2 mutations in two patients with megalencephaly-related syndromes: MCAP and MPPH.

PubMed ID: 23745724

DOI: 10.1111/cge.12188

PubMed ID: 22729224

Title: De novo germline and postzygotic mutations in AKT3, PIK3R2 and PIK3CA cause a spectrum of related megalencephaly syndromes.

PubMed ID: 22729224

DOI: 10.1038/ng.2331

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 28903391

Title: Cancer/testis antigen PIWIL2 suppresses circadian rhythms by regulating the stability and activity of BMAL1 and CLOCK.

PubMed ID: 28903391

DOI: 10.18632/oncotarget.18973

PubMed ID: 26520804

Title: Characterisation of mutations of the phosphoinositide-3-kinase regulatory subunit, PIK3R2, in perisylvian polymicrogyria: a next-generation sequencing study.

PubMed ID: 26520804

DOI: 10.1016/s1474-4422(15)00278-1

PubMed ID: 26860062

Title: De novo PIK3R2 variant causes polymicrogyria, corpus callosum hyperplasia and focal cortical dysplasia.

PubMed ID: 26860062

DOI: 10.1038/ejhg.2016.7

Sequence Information:

  • Length: 728
  • Mass: 81545
  • Checksum: ADAC3E4B61F3F44A
  • Sequence:
    • MAGPEGFQYR ALYPFRRERP EDLELLPGDV LVVSRAALQA LGVAEGGERC PQSVGWMPGL 
NERTRQRGDF PGTYVEFLGP VALARPGPRP RGPRPLPARP RDGAPEPGLT LPDLPEQFSP 
PDVAPPLLVK LVEAIERTGL DSESHYRPEL PAPRTDWSLS DVDQWDTAAL ADGIKSFLLA 
LPAPLVTPEA SAEARRALRE AAGPVGPALE PPTLPLHRAL TLRFLLQHLG RVASRAPALG 
PAVRALGATF GPLLLRAPPP PSSPPPGGAP DGSEPSPDFP ALLVEKLLQE HLEEQEVAPP 
ALPPKPPKAK PASTVLANGG SPPSLQDAEW YWGDISREEV NEKLRDTPDG TFLVRDASSK 
IQGEYTLTLR KGGNNKLIKV FHRDGHYGFS EPLTFCSVVD LINHYRHESL AQYNAKLDTR 
LLYPVSKYQQ DQIVKEDSVE AVGAQLKVYH QQYQDKSREY DQLYEEYTRT SQELQMKRTA 
IEAFNETIKI FEEQGQTQEK CSKEYLERFR REGNEKEMQR ILLNSERLKS RIAEIHESRT 
KLEQQLRAQA SDNREIDKRM NSLKPDLMQL RKIRDQYLVW LTQKGARQKK INEWLGIKNE 
TEDQYALMED EDDLPHHEER TWYVGKINRT QAEEMLSGKR DGTFLIRESS QRGCYACSVV 
VDGDTKHCVI YRTATGFGFA EPYNLYGSLK ELVLHYQHAS LVQHNDALTV TLAHPVRAPG 
PGPPPAAR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.