Details for: BCL11A

Gene ID: 53335

Symbol: BCL11A

Ensembl ID: ENSG00000119866

Description: BCL11 transcription factor A

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 223.4077
    Cell Significance Index: -34.7500
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 87.8596
    Cell Significance Index: -22.2900
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 79.9248
    Cell Significance Index: -32.4700
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 77.2184
    Cell Significance Index: -39.7200
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 57.5242
    Cell Significance Index: -38.6000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 34.0196
    Cell Significance Index: -32.4800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 31.5259
    Cell Significance Index: -38.8700
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 10.1380
    Cell Significance Index: -40.0100
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 7.6595
    Cell Significance Index: 167.7200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 7.0535
    Cell Significance Index: 197.1200
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 4.7968
    Cell Significance Index: 42.5800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 4.4215
    Cell Significance Index: 285.2600
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 3.9340
    Cell Significance Index: -8.6100
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 3.1694
    Cell Significance Index: 84.7800
  • Cell Name: epidermal cell (CL0000362)
    Fold Change: 2.7323
    Cell Significance Index: 6.1600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 2.4700
    Cell Significance Index: 401.7200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.3276
    Cell Significance Index: 466.9200
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 2.1751
    Cell Significance Index: 62.0700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 2.0291
    Cell Significance Index: 124.7200
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 2.0040
    Cell Significance Index: 30.2000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.8833
    Cell Significance Index: 105.6800
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 1.8059
    Cell Significance Index: 43.3100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 1.6244
    Cell Significance Index: 71.8500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.4954
    Cell Significance Index: 89.7800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 1.4646
    Cell Significance Index: 172.7200
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 1.4419
    Cell Significance Index: 101.9800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 1.4362
    Cell Significance Index: 96.5700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 1.3687
    Cell Significance Index: 51.8300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.3278
    Cell Significance Index: 101.9000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.2775
    Cell Significance Index: 17.4300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 1.2325
    Cell Significance Index: 544.9000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.0284
    Cell Significance Index: 101.7300
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.9414
    Cell Significance Index: 651.1400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.8556
    Cell Significance Index: 169.8000
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.8518
    Cell Significance Index: 17.8300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.8033
    Cell Significance Index: 55.5500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.5886
    Cell Significance Index: 16.9600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.3526
    Cell Significance Index: 15.9800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.3302
    Cell Significance Index: 59.5300
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 0.3051
    Cell Significance Index: 2.3400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.2612
    Cell Significance Index: 12.1800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2011
    Cell Significance Index: 38.2700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.1878
    Cell Significance Index: 27.3000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.1791
    Cell Significance Index: 3.8800
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.1622
    Cell Significance Index: 2.5100
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.1350
    Cell Significance Index: 2.8000
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 0.1183
    Cell Significance Index: 2.3400
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 0.0724
    Cell Significance Index: 2.3700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0619
    Cell Significance Index: 22.1900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0509
    Cell Significance Index: 6.2600
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 0.0470
    Cell Significance Index: 0.2900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.0400
    Cell Significance Index: 4.6600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0319
    Cell Significance Index: 1.1200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0244
    Cell Significance Index: 4.1600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0136
    Cell Significance Index: 7.4100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.0129
    Cell Significance Index: 11.6300
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.0106
    Cell Significance Index: 0.2400
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0034
    Cell Significance Index: -0.0500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0044
    Cell Significance Index: -0.1400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0150
    Cell Significance Index: -11.0900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0177
    Cell Significance Index: -33.3900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0265
    Cell Significance Index: -16.5500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0290
    Cell Significance Index: -53.5200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0340
    Cell Significance Index: -52.3200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0400
    Cell Significance Index: -5.1300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0404
    Cell Significance Index: -54.9900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0425
    Cell Significance Index: -32.1700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0439
    Cell Significance Index: -24.7500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0474
    Cell Significance Index: -34.7400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0519
    Cell Significance Index: -32.9900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0819
    Cell Significance Index: -37.1800
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0865
    Cell Significance Index: -2.2100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0972
    Cell Significance Index: -4.5700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1095
    Cell Significance Index: -31.5100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1288
    Cell Significance Index: -27.1200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1767
    Cell Significance Index: -22.8300
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.1900
    Cell Significance Index: -2.5400
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.1964
    Cell Significance Index: -2.1400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2195
    Cell Significance Index: -7.0300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.2215
    Cell Significance Index: -24.1000
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.2322
    Cell Significance Index: -3.3300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.2356
    Cell Significance Index: -32.3600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2464
    Cell Significance Index: -28.2300
  • Cell Name: IgG-negative class switched memory B cell (CL0002117)
    Fold Change: -0.2706
    Cell Significance Index: -1.2100
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.2921
    Cell Significance Index: -6.2000
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.3289
    Cell Significance Index: -37.5400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.3329
    Cell Significance Index: -17.4800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.3491
    Cell Significance Index: -35.6600
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.3869
    Cell Significance Index: -4.0100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3881
    Cell Significance Index: -40.4100
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: -0.4120
    Cell Significance Index: -2.4500
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: -0.4243
    Cell Significance Index: -4.2800
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: -0.4296
    Cell Significance Index: -2.8000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.4480
    Cell Significance Index: -11.2000
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.4577
    Cell Significance Index: -7.6600
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.4587
    Cell Significance Index: -12.2900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4601
    Cell Significance Index: -36.4400
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.4670
    Cell Significance Index: -11.6500
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.4889
    Cell Significance Index: -36.4400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.5119
    Cell Significance Index: -26.5900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** BCL11A is a transcription factor that belongs to the basic helix-loop-helix (bHLH) family of proteins. It is primarily expressed in hematopoietic cells, including polychromatophilic erythroblasts, hematopoietic oligopotent progenitor cells, and peripheral blood mononuclear cells. BCL11A also exhibits expression in other cell types, such as mucosal type mast cells, Purkinje cells, and basal epithelial cells of the tracheobronchial tree. The gene is involved in various signaling pathways, including those mediated by Alk (Alk-related kinase) mutants, which can lead to aberrant signaling and cellular dysregulation. **Pathways and Functions** BCL11A is involved in multiple signaling pathways, including: 1. **Alk mutants bind tkis**: BCL11A interacts with Alk mutants, which can lead to aberrant signaling and cellular dysregulation. 2. **Cellular response to l-glutamate**: BCL11A regulates the expression of genes involved in the cellular response to l-glutamate, a neurotransmitter. 3. **Disease**: BCL11A is involved in various diseases, including lymphoma, leukemia, and neurological disorders. 4. **Dna-binding transcription factor activity**: BCL11A acts as a transcription factor, regulating the expression of target genes. 5. **Metal ion binding**: BCL11A binds to metal ions, which can influence its transcriptional activity. BCL11A functions as a transcriptional regulator, influencing the expression of genes involved in various cellular processes, including: 1. **Gene expression**: BCL11A regulates the expression of genes involved in immune cell development, differentiation, and function. 2. **Neuron development**: BCL11A is involved in the regulation of neuron development, including axon extension, branching morphogenesis, and dendrite development. 3. **Transcription by rna polymerase ii**: BCL11A regulates the expression of genes involved in transcription by RNA polymerase II. **Clinical Significance** BCL11A has been implicated in various immune-related disorders, including: 1. **Lymphoma**: BCL11A mutations have been identified in certain types of lymphoma, including B-cell lymphoma. 2. **Leukemia**: BCL11A is involved in the regulation of leukemic cell development and survival. 3. **Neurological disorders**: BCL11A mutations have been associated with neurological disorders, including schizophrenia and autism spectrum disorder. As an immunologist, understanding the functions and clinical significance of BCL11A can provide insights into its potential role in immune-related disorders and the development of novel therapeutic strategies. Further research is needed to elucidate the mechanisms by which BCL11A influences immune cell development, differentiation, and function, and to explore its potential as a therapeutic target.

Genular Protein ID: 1834694103

Symbol: BC11A_HUMAN

Name: B-cell CLL/lymphoma 11A

UniProtKB Accession Codes:

Q9H165 D6W5D7 Q66LN6 Q86W14 Q8WU92 Q96JL6 Q9H163 Q9H164 Q9H3G9 Q9NWA7

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 14 Ensembl 5 ExpressionAtlas 1 GO 35 Gene3D 1 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 4 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PDB 5 PDBsum 5 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 RNAct 1 Reactome 2 RefSeq 5 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 11719382

Title: The BCL11 gene family: involvement of BCL11A in lymphoid malignancies.

PubMed ID: 11719382

DOI: 10.1182/blood.v98.12.3413

PubMed ID: 11347906

Title: Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 11347906

DOI: 10.1093/dnares/8.2.85

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11161790

Title: Human EVI9, a homologue of the mouse myeloid leukemia gene, is expressed in the hematopoietic progenitors and down-regulated during myeloid differentiation of HL60 cells.

PubMed ID: 11161790

DOI: 10.1006/geno.2000.6385

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16704730

Title: Functional studies of BCL11A: characterization of the conserved BCL11A-XL splice variant and its interaction with BCL6 in nuclear paraspeckles of germinal center B cells.

PubMed ID: 16704730

DOI: 10.1186/1476-4598-5-18

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 26375765

Title: Hemoglobin switching's surprise: the versatile transcription factor BCL11A is a master repressor of fetal hemoglobin.

PubMed ID: 26375765

DOI: 10.1016/j.gde.2015.08.001

PubMed ID: 25755297

Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.

PubMed ID: 25755297

DOI: 10.1074/mcp.o114.044792

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

PubMed ID: 17767159

Title: A QTL influencing F cell production maps to a gene encoding a zinc-finger protein on chromosome 2p15.

PubMed ID: 17767159

DOI: 10.1038/ng2108

PubMed ID: 23644491

Title: Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy.

PubMed ID: 23644491

DOI: 10.1038/ng.2628

PubMed ID: 27453576

Title: BCL11A haploinsufficiency causes an intellectual disability syndrome and dysregulates transcription.

PubMed ID: 27453576

DOI: 10.1016/j.ajhg.2016.05.030

PubMed ID: 29606353

Title: Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch.

PubMed ID: 29606353

DOI: 10.1016/j.cell.2018.03.016

PubMed ID: 30250039

Title: Functional characterization of TBR1 variants in neurodevelopmental disorder.

PubMed ID: 30250039

DOI: 10.1038/s41598-018-32053-6

Sequence Information:

  • Length: 835
  • Mass: 91197
  • Checksum: D36A7D0BE6976DCF
  • Sequence:
    • MSRRKQGKPQ HLSKREFSPE PLEAILTDDE PDHGPLGAPE GDHDLLTCGQ CQMNFPLGDI 
LIFIEHKRKQ CNGSLCLEKA VDKPPSPSPI EMKKASNPVE VGIQVTPEDD DCLSTSSRGI 
CPKQEHIADK LLHWRGLSSP RSAHGALIPT PGMSAEYAPQ GICKDEPSSY TCTTCKQPFT 
SAWFLLQHAQ NTHGLRIYLE SEHGSPLTPR VGIPSGLGAE CPSQPPLHGI HIADNNPFNL 
LRIPGSVSRE ASGLAEGRFP PTPPLFSPPP RHHLDPHRIE RLGAEEMALA THHPSAFDRV 
LRLNPMAMEP PAMDFSRRLR ELAGNTSSPP LSPGRPSPMQ RLLQPFQPGS KPPFLATPPL 
PPLQSAPPPS QPPVKSKSCE FCGKTFKFQS NLVVHRRSHT GEKPYKCNLC DHACTQASKL 
KRHMKTHMHK SSPMTVKSDD GLSTASSPEP GTSDLVGSAS SALKSVVAKF KSENDPNLIP 
ENGDEEEEED DEEEEEEEEE EEEELTESER VDYGFGLSLE AARHHENSSR GAVVGVGDES 
RALPDVMQGM VLSSMQHFSE AFHQVLGEKH KRGHLAEAEG HRDTCDEDSV AGESDRIDDG 
TVNGRGCSPG ESASGGLSKK LLLGSPSSLS PFSKRIKLEK EFDLPPAAMP NTENVYSQWL 
AGYAASRQLK DPFLSFGDSR QSPFASSSEH SSENGSLRFS TPPGELDGGI SGRSGTGSGG 
STPHISGPGP GRPSSKEGRR SDTCEYCGKV FKNCSNLTVH RRSHTGERPY KCELCNYACA 
QSSKLTRHMK THGQVGKDVY KCEICKMPFS VYSTLEKHMK KWHSDRVLNN DIKTE

Genular Protein ID: 3733213228

Symbol: D9YZV9_HUMAN

Name: N/A

UniProtKB Accession Codes:

D9YZV9

Database IDs:

ARBA 8 AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 4 ExpressionAtlas 1 GO 6 Gene3D 1 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 3 PROSITE-ProRule 1 Pfam 1 RefSeq 1 SAM 1 SMART 1 SMR 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

Sequence Information:

  • Length: 773
  • Mass: 83860
  • Checksum: 251E8A1F3EB87956
  • Sequence:
    • MSRRKQGKPQ HLSKREFSPE PLEAILTDDE PDHGPLGAPE GDHDLLTCGQ CQMNFPLGDI 
LIFIEHKRKQ CNGSLCLEKA VDKPPSPSPI EMKKASNPVE VGIQVTPEDD DCLSTSSRGI 
CPKQEHIADK LLHWRGLSSP RSAHGALIPT PGMSAEYAPQ GICKDEPSSY TCTTCKQPFT 
SAWFLLQHAQ NTHGLRIYLE SEHGSPLTPR VGIPSGLGAE CPSQPPLHGI HIADNNPFNL 
LRIPGSVSRE ASGLAEGRFP PTPPLFSPPP RHHLDPHRIE RLGAEEMALA THHPSAFDRV 
LRLNPMAMEP PAMDFSRRLR ELAGNTSSPP LSPGRPSPMQ RLLQPFQPGS KPPFLATPPL 
PPLQSAPPPS QPPVKSKSCE FCGKTFKFQS NLVVHRRSHT GEKPYKCNLC DHACTQASKL 
KRHMKTHMHK SSPMTVKSDD GLSTASSPEP GTSDLVGSAS SALKSVVAKF KSENDPNLIP 
ENGDEEEEED DEEEEEEEEE EEEELTESER VDYGFGLSLE AARHHENSSR GAVVGVGDES 
RALPDVMQGM VLSSMQHFSE AFHQVLGEKH KRGHLAEAEG HRDTCDEDSV AGESDRIDDG 
TVNGRGCSPG ESASGGLSKK LLLGSPSSLS PFSKRIKLEK EFDLPPAAMP NTENVYSQWL 
AGYAASRQLK DPFLSFGDSR QSPFASSSEH SSENGSLRFS TPPGELDGGI SGRSGTGSGG 
STPHISGPGP GRPSSKEGRR SDTCSSHTPI RRSTQRAQDV WQFSDGSSRA LKF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.