Details for: POU4F2

Gene ID: 5458

Symbol: POU4F2

Ensembl ID: ENSG00000151615

Description: POU class 4 homeobox 2

Associated with

  • Gene expression (transcription)
    (R-HSA-74160)
  • Generic transcription pathway
    (R-HSA-212436)
  • Regulation of tp53 activity
    (R-HSA-5633007)
  • Regulation of tp53 activity through association with co-factors
    (R-HSA-6804759)
  • Rna polymerase ii transcription
    (R-HSA-73857)
  • Transcriptional regulation by tp53
    (R-HSA-3700989)
  • Axon extension
    (GO:0048675)
  • Axon guidance
    (GO:0007411)
  • Cellular response to cytokine stimulus
    (GO:0071345)
  • Cellular response to estradiol stimulus
    (GO:0071392)
  • Cellular response to insulin stimulus
    (GO:0032869)
  • Chromatin
    (GO:0000785)
  • Cytoplasm
    (GO:0005737)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna-binding transcription repressor activity, rna polymerase ii-specific
    (GO:0001227)
  • Dorsal root ganglion development
    (GO:1990791)
  • Estrogen receptor signaling pathway
    (GO:0030520)
  • Euchromatin
    (GO:0000791)
  • Heart development
    (GO:0007507)
  • Intrinsic apoptotic signaling pathway by p53 class mediator
    (GO:0072332)
  • Mapk cascade
    (GO:0000165)
  • Negative regulation of adipose tissue development
    (GO:1904178)
  • Negative regulation of amacrine cell differentiation
    (GO:1902870)
  • Negative regulation of cell differentiation
    (GO:0045596)
  • Negative regulation of dna-binding transcription factor activity
    (GO:0043433)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Neuromuscular process controlling balance
    (GO:0050885)
  • Neuron differentiation
    (GO:0030182)
  • Nuclear speck
    (GO:0016607)
  • Nucleoplasm
    (GO:0005654)
  • Nucleus
    (GO:0005634)
  • P53 binding
    (GO:0002039)
  • Positive regulation of axon extension
    (GO:0045773)
  • Positive regulation of cell differentiation
    (GO:0045597)
  • Positive regulation of d-glucose import
    (GO:0046326)
  • Positive regulation of osteoclast differentiation
    (GO:0045672)
  • Positive regulation of programmed cell death
    (GO:0043068)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Positive regulation of transcription regulatory region dna binding
    (GO:2000679)
  • Promoter-specific chromatin binding
    (GO:1990841)
  • Protein binding
    (GO:0005515)
  • Regulation of dna-binding transcription factor activity
    (GO:0051090)
  • Regulation of retinal ganglion cell axon guidance
    (GO:0090259)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Retina development in camera-type eye
    (GO:0060041)
  • Retinal ganglion cell axon guidance
    (GO:0031290)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Sensory perception of sound
    (GO:0007605)
  • Transcription regulator complex
    (GO:0005667)

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: ganglion interneuron (CL0000397)
    Fold Change: 2.1365
    Cell Significance Index: 17.4900
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 1.4473
    Cell Significance Index: 24.7400
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: 0.9753
    Cell Significance Index: 9.4400
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: 0.4504
    Cell Significance Index: 6.4500
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: 0.3744
    Cell Significance Index: 3.9000
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: 0.3337
    Cell Significance Index: 3.7900
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 0.1302
    Cell Significance Index: 1.0800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.0658
    Cell Significance Index: 3.6900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0509
    Cell Significance Index: 3.2100
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.0365
    Cell Significance Index: 0.8000
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: 0.0344
    Cell Significance Index: 0.3400
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 0.0024
    Cell Significance Index: 0.0300
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0001
    Cell Significance Index: -0.0600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0003
    Cell Significance Index: -0.1900
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.0008
    Cell Significance Index: -0.0100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0011
    Cell Significance Index: -0.1900
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: -0.0013
    Cell Significance Index: -0.0200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0017
    Cell Significance Index: -3.2700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0039
    Cell Significance Index: -1.1300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0074
    Cell Significance Index: -0.2000
  • Cell Name: retinal astrocyte (CL4033015)
    Fold Change: -0.0096
    Cell Significance Index: -0.0900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0116
    Cell Significance Index: -0.6100
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: -0.0120
    Cell Significance Index: -0.1600
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.0130
    Cell Significance Index: -0.2600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0154
    Cell Significance Index: -3.0900
  • Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
    Fold Change: -0.0187
    Cell Significance Index: -0.2100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0229
    Cell Significance Index: -3.3300
  • Cell Name: pancreatic stellate cell (CL0002410)
    Fold Change: -0.0231
    Cell Significance Index: -0.2900
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: -0.0242
    Cell Significance Index: -0.3400
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.0246
    Cell Significance Index: -0.3100
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: -0.0291
    Cell Significance Index: -0.2100
  • Cell Name: peripheral nervous system neuron (CL2000032)
    Fold Change: -0.0328
    Cell Significance Index: -0.2600
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.0351
    Cell Significance Index: -0.4100
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: -0.0365
    Cell Significance Index: -0.5000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0411
    Cell Significance Index: -1.9300
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.0527
    Cell Significance Index: -0.5000
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0597
    Cell Significance Index: -1.5200
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: -0.0608
    Cell Significance Index: -0.7400
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0680
    Cell Significance Index: -1.6300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0723
    Cell Significance Index: -1.9300
  • Cell Name: progenitor cell (CL0011026)
    Fold Change: -0.0753
    Cell Significance Index: -0.8000
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: -0.0778
    Cell Significance Index: -1.2600
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -0.0803
    Cell Significance Index: -1.0700
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.0892
    Cell Significance Index: -1.1900
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0956
    Cell Significance Index: -3.1300
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0995
    Cell Significance Index: -3.1700
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: -0.1050
    Cell Significance Index: -1.1400
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: -0.1061
    Cell Significance Index: -0.6900
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.1065
    Cell Significance Index: -1.2700
  • Cell Name: chondrocyte (CL0000138)
    Fold Change: -0.1099
    Cell Significance Index: -1.2700
  • Cell Name: T follicular helper cell (CL0002038)
    Fold Change: -0.1113
    Cell Significance Index: -1.1800
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: -0.1127
    Cell Significance Index: -1.3600
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.1135
    Cell Significance Index: -3.0400
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: -0.1136
    Cell Significance Index: -1.4400
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.1153
    Cell Significance Index: -3.2900
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.1155
    Cell Significance Index: -1.5100
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1156
    Cell Significance Index: -3.0400
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.1158
    Cell Significance Index: -3.4100
  • Cell Name: enteric neuron (CL0007011)
    Fold Change: -0.1175
    Cell Significance Index: -0.8500
  • Cell Name: mesothelial cell (CL0000077)
    Fold Change: -0.1176
    Cell Significance Index: -1.4300
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.1295
    Cell Significance Index: -3.2300
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: -0.1364
    Cell Significance Index: -1.9800
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.1384
    Cell Significance Index: -1.4600
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: -0.1388
    Cell Significance Index: -1.6400
  • Cell Name: vein endothelial cell (CL0002543)
    Fold Change: -0.1402
    Cell Significance Index: -1.5200
  • Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell (CL0000895)
    Fold Change: -0.1402
    Cell Significance Index: -1.2100
  • Cell Name: blood vessel endothelial cell (CL0000071)
    Fold Change: -0.1408
    Cell Significance Index: -1.5300
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: -0.1431
    Cell Significance Index: -1.9300
  • Cell Name: muscle cell (CL0000187)
    Fold Change: -0.1431
    Cell Significance Index: -1.3700
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.1437
    Cell Significance Index: -1.7100
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: -0.1469
    Cell Significance Index: -1.5800
  • Cell Name: vascular associated smooth muscle cell (CL0000359)
    Fold Change: -0.1469
    Cell Significance Index: -1.5600
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.1474
    Cell Significance Index: -3.5700
  • Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
    Fold Change: -0.1521
    Cell Significance Index: -1.6400
  • Cell Name: conventional dendritic cell (CL0000990)
    Fold Change: -0.1549
    Cell Significance Index: -1.8300
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1550
    Cell Significance Index: -3.2900
  • Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
    Fold Change: -0.1587
    Cell Significance Index: -1.3700
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: -0.1608
    Cell Significance Index: -1.8200
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.1634
    Cell Significance Index: -3.2800
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.1649
    Cell Significance Index: -3.2600
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: -0.1700
    Cell Significance Index: -1.3100
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.1717
    Cell Significance Index: -2.1300
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.1719
    Cell Significance Index: -3.3600
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.1720
    Cell Significance Index: -2.5400
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: -0.1772
    Cell Significance Index: -2.3300
  • Cell Name: mononuclear phagocyte (CL0000113)
    Fold Change: -0.1775
    Cell Significance Index: -1.5000
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.1785
    Cell Significance Index: -3.3000
  • Cell Name: common dendritic progenitor (CL0001029)
    Fold Change: -0.1816
    Cell Significance Index: -1.8900
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: -0.1861
    Cell Significance Index: -1.9300
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.1881
    Cell Significance Index: -2.2500
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.1891
    Cell Significance Index: -3.2700
  • Cell Name: colon epithelial cell (CL0011108)
    Fold Change: -0.1891
    Cell Significance Index: -1.1100
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: -0.1892
    Cell Significance Index: -2.4500
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: -0.1910
    Cell Significance Index: -2.1200
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.1920
    Cell Significance Index: -3.2900
  • Cell Name: ON parasol ganglion cell (CL4033052)
    Fold Change: -0.1931
    Cell Significance Index: -2.4100
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1939
    Cell Significance Index: -3.2500
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: -0.1983
    Cell Significance Index: -1.6400
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: -0.2044
    Cell Significance Index: -2.9900
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.2058
    Cell Significance Index: -2.5300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **POU Domain:** The POU domain is a characteristic feature of POU4F2, which allows it to bind to specific DNA sequences and regulate gene expression. 2. **Cellular Expression:** POU4F2 is expressed in a wide range of cell types, including erythrocytes, blood vessel endothelial cells, retinal bipolar neurons, and cerebral cortex GABAergic interneurons. 3. **Transcriptional Regulation:** POU4F2 acts as a transcription factor, regulating the expression of target genes involved in various developmental processes and cellular differentiation. 4. **Signaling Pathways:** POU4F2 is involved in several signaling pathways, including axon extension, axon guidance, cellular response to cytokine and insulin stimuli, and intrinsic apoptotic signaling pathway by p53 class mediator. **Pathways and Functions:** 1. **Axon Extension and Guidance:** POU4F2 is involved in the regulation of axon extension and guidance, essential for the development of the nervous system. 2. **Cellular Response to Cytokine Stimuli:** POU4F2 regulates the expression of genes involved in the cellular response to cytokine stimuli, which is crucial for immune response and inflammation. 3. **Cellular Response to Insulin Stimuli:** POU4F2 is involved in the regulation of gene expression in response to insulin stimuli, which is essential for glucose metabolism and energy homeostasis. 4. **Intrinsic Apoptotic Signaling Pathway:** POU4F2 regulates the expression of genes involved in the intrinsic apoptotic signaling pathway by p53 class mediator, which is crucial for programmed cell death and tissue homeostasis. 5. **Transcriptional Regulation:** POU4F2 acts as a transcription factor, regulating the expression of target genes involved in various developmental processes and cellular differentiation. **Clinical Significance:** 1. **Developmental Disorders:** Mutations in the POU4F2 gene have been associated with developmental disorders, such as congenital heart defects and brain development abnormalities. 2. **Cancer:** POU4F2 has been implicated in cancer development, particularly in the regulation of cell differentiation and apoptosis. 3. **Neurological Disorders:** POU4F2 has been implicated in neurological disorders, such as Alzheimer's disease and Parkinson's disease, where it regulates the expression of genes involved in neuronal differentiation and survival. 4. **Diabetes:** POU4F2 has been implicated in diabetes, particularly in the regulation of glucose metabolism and energy homeostasis. In conclusion, the POU4F2 gene plays a critical role in various developmental processes and cellular differentiation, and its dysregulation has been implicated in several diseases, including developmental disorders, cancer, and neurological disorders. Further research is needed to elucidate the mechanisms underlying POU4F2's functions and to explore its potential as a therapeutic target for diseases associated with its dysregulation.

Genular Protein ID: 3884449748

Symbol: PO4F2_HUMAN

Name: Brain-specific homeobox/POU domain protein 3B

UniProtKB Accession Codes:

Q12837 B1PJR6 B2RC84 Q13883 Q14987

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 8 Ensembl 1 GO 43 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 1 PRO 1 PROSITE 5 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RNAct 1 Reactome 1 RefSeq 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 7691107

Title: Brn-3b: a POU domain gene expressed in a subset of retinal ganglion cells.

PubMed ID: 7691107

DOI: 10.1016/0896-6273(93)90079-7

PubMed ID: 8332509

Title: The human Brn-3b POU transcription factor shows only limited homology to the Brn-3a/RDC-1 factor outside the conserved POU domain.

PubMed ID: 8332509

DOI: 10.1093/nar/21.12.2946

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19266028

Title: Genome-wide analysis of histidine repeats reveals their role in the localization of human proteins to the nuclear speckles compartment.

PubMed ID: 19266028

DOI: 10.1371/journal.pgen.1000397

PubMed ID: 8234287

Title: Differential expression of four members of the POU family of proteins in activated and phorbol 12-myristate 13-acetate-treated Jurkat T cells.

PubMed ID: 8234287

DOI: 10.1073/pnas.90.21.10260

PubMed ID: 11526481

Title: The Brn-3b POU family transcription factor regulates the cellular growth, proliferation, and anchorage dependence of MCF7 human breast cancer cells.

PubMed ID: 11526481

DOI: 10.1038/sj.onc.1204491

PubMed ID: 23805044

Title: RIT2, a neuron-specific small guanosine triphosphatase, is expressed in retinal neuronal cells and its promoter is modulated by the POU4 transcription factors.

PubMed ID: 23805044

Sequence Information:

  • Length: 409
  • Mass: 43087
  • Checksum: 42E2C174674E8DFC
  • Sequence:
    • MMMMSLNSKQ AFSMPHGGSL HVEPKYSALH STSPGSSAPI APSASSPSSS SNAGGGGGGG 
GGGGGGGGRS SSSSSSGSSG GGGSEAMRRA CLPTPPSNIF GGLDESLLAR AEALAAVDIV 
SQSKSHHHHP PHHSPFKPDA TYHTMNTIPC TSAASSSSVP ISHPSALAGT HHHHHHHHHH 
HHQPHQALEG ELLEHLSPGL ALGAMAGPDG AVVSTPAHAP HMATMNPMHQ AALSMAHAHG 
LPSHMGCMSD VDADPRDLEA FAERFKQRRI KLGVTQADVG SALANLKIPG VGSLSQSTIC 
RFESLTLSHN NMIALKPILQ AWLEEAEKSH REKLTKPELF NGAEKKRKRT SIAAPEKRSL 
EAYFAIQPRP SSEKIAAIAE KLDLKKNVVR VWFCNQRQKQ KRMKYSAGI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.