Details for: POU5F1

Gene ID: 5460

Symbol: POU5F1

Ensembl ID: ENSG00000204531

Description: POU class 5 homeobox 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: germ cell (CL0000586)
    Fold Change: 6.9808
    Cell Significance Index: 52.7100
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 3.9509
    Cell Significance Index: 59.2000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 3.4652
    Cell Significance Index: 99.8400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 3.4628
    Cell Significance Index: 179.8800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 2.4201
    Cell Significance Index: 52.4300
  • Cell Name: intrahepatic cholangiocyte (CL0002538)
    Fold Change: 1.6117
    Cell Significance Index: 6.0700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.4228
    Cell Significance Index: 64.4900
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 1.0297
    Cell Significance Index: 9.1400
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 1.0153
    Cell Significance Index: 14.7400
  • Cell Name: large intestine goblet cell (CL1000320)
    Fold Change: 0.9790
    Cell Significance Index: 10.6100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.6955
    Cell Significance Index: 68.8100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.6118
    Cell Significance Index: 552.3700
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.5895
    Cell Significance Index: 13.6200
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.4985
    Cell Significance Index: 10.3400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.4841
    Cell Significance Index: 13.5300
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.4040
    Cell Significance Index: 6.8100
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.4028
    Cell Significance Index: 5.9500
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3731
    Cell Significance Index: 60.6800
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.3725
    Cell Significance Index: 40.5200
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.3246
    Cell Significance Index: 19.4900
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.3081
    Cell Significance Index: 10.8300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.3068
    Cell Significance Index: 6.5400
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 0.2901
    Cell Significance Index: 1.7900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2353
    Cell Significance Index: 16.2800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.2023
    Cell Significance Index: 23.5700
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.1578
    Cell Significance Index: 2.2700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.1547
    Cell Significance Index: 4.2100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1232
    Cell Significance Index: 67.3000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.1217
    Cell Significance Index: 1.6600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1204
    Cell Significance Index: 22.9200
  • Cell Name: glandular epithelial cell (CL0000150)
    Fold Change: 0.1156
    Cell Significance Index: 0.9200
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 0.1138
    Cell Significance Index: 0.8700
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.0925
    Cell Significance Index: 2.4800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0696
    Cell Significance Index: 1.7400
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: 0.0548
    Cell Significance Index: 0.7600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0537
    Cell Significance Index: 9.6800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0404
    Cell Significance Index: 5.5500
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: 0.0342
    Cell Significance Index: 0.4900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0336
    Cell Significance Index: 4.1300
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.0266
    Cell Significance Index: 1.3400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0258
    Cell Significance Index: 5.1300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0160
    Cell Significance Index: 2.7400
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.0148
    Cell Significance Index: 0.2100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0102
    Cell Significance Index: 3.6700
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0093
    Cell Significance Index: 17.1600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0086
    Cell Significance Index: 13.2300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0079
    Cell Significance Index: 1.5900
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.0061
    Cell Significance Index: 0.1000
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0045
    Cell Significance Index: 2.0100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0031
    Cell Significance Index: 2.2600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0014
    Cell Significance Index: 0.1100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0010
    Cell Significance Index: 0.0600
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0002
    Cell Significance Index: -0.2200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0003
    Cell Significance Index: -0.4800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0015
    Cell Significance Index: -1.1000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0018
    Cell Significance Index: -0.2100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0043
    Cell Significance Index: -3.1600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0045
    Cell Significance Index: -2.8500
  • Cell Name: intestinal crypt stem cell of large intestine (CL0009016)
    Fold Change: -0.0046
    Cell Significance Index: -0.0400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0052
    Cell Significance Index: -2.9200
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.0060
    Cell Significance Index: -0.0900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0061
    Cell Significance Index: -0.6200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0062
    Cell Significance Index: -2.8300
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: -0.0073
    Cell Significance Index: -0.0400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0111
    Cell Significance Index: -0.6800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0152
    Cell Significance Index: -2.2100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0153
    Cell Significance Index: -1.9800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0159
    Cell Significance Index: -1.8700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0162
    Cell Significance Index: -3.4100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0192
    Cell Significance Index: -2.4600
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.0195
    Cell Significance Index: -0.3100
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0216
    Cell Significance Index: -1.5300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0228
    Cell Significance Index: -0.7300
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: -0.0244
    Cell Significance Index: -0.2200
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.0244
    Cell Significance Index: -0.3500
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: -0.0245
    Cell Significance Index: -0.1600
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: -0.0251
    Cell Significance Index: -0.2600
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.0271
    Cell Significance Index: -0.2500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0285
    Cell Significance Index: -1.3300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0287
    Cell Significance Index: -2.9900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0337
    Cell Significance Index: -1.5900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0401
    Cell Significance Index: -3.1800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0443
    Cell Significance Index: -3.3000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0453
    Cell Significance Index: -2.3800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0465
    Cell Significance Index: -3.0000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0495
    Cell Significance Index: -2.1900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0497
    Cell Significance Index: -2.7900
  • Cell Name: mucous neck cell (CL0000651)
    Fold Change: -0.0504
    Cell Significance Index: -0.2400
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0560
    Cell Significance Index: -2.1200
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.0564
    Cell Significance Index: -2.0700
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0576
    Cell Significance Index: -2.3600
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0589
    Cell Significance Index: -3.0700
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0599
    Cell Significance Index: -2.1000
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0642
    Cell Significance Index: -1.6500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0647
    Cell Significance Index: -2.0600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0660
    Cell Significance Index: -2.1600
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.0660
    Cell Significance Index: -1.6100
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0665
    Cell Significance Index: -1.1400
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: -0.0735
    Cell Significance Index: -0.6700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** POU5F1 is a member of the POU domain-containing transcription factor family, characterized by its high degree of homology with other POU domain-containing proteins. It is a dimeric transcription factor, composed of two POU domains (POU1 and POU2), which are essential for its DNA-binding activity. POU5F1 is highly expressed in embryonic stem cells, primordial germ cells, and certain types of cancer cells, where it maintains pluripotency and self-renewal. **Pathways and Functions:** POU5F1 is a central regulator of pluripotency, controlling the expression of genes involved in cell fate specification, differentiation, and proliferation. It acts as a transcriptional activator, promoting the expression of genes related to cell proliferation, such as SOX2, NANOG, and LEF1, while repressing genes related to differentiation, such as PAX6 and TCF3. POU5F1 also regulates the expression of microRNAs (miRNAs) involved in cell proliferation and differentiation. Its activity is essential for the maintenance of embryonic stem cells, primordial germ cells, and certain types of cancer cells, where it ensures the preservation of pluripotency and self-renewal. **Clinical Significance:** POU5F1 has been implicated in various diseases, including cancer, where its overexpression is associated with tumorigenesis and poor prognosis. In cancer therapy, POU5F1 has been used as a biomarker for the detection of cancer stem cells, which are thought to be responsible for cancer relapse and metastasis. Additionally, POU5F1 has been explored as a potential therapeutic target for the treatment of various diseases, including leukemia, lymphoma, and certain types of solid tumors. Furthermore, POU5F1 has been identified as a key regulator of the immune system, where it plays a role in the development and function of regulatory T cells (Tregs). Aberrant expression of POU5F1 has been linked to autoimmune diseases, such as multiple sclerosis and type 1 diabetes, where it may contribute to the dysregulation of the immune response. In conclusion, POU5F1 is a multifunctional transcription factor that plays a critical role in the regulation of pluripotency, self-renewal, and differentiation in various cell types. Its dysregulation has been implicated in various diseases, including cancer, autoimmune diseases, and immune-related disorders. Further research is needed to fully elucidate the mechanisms of POU5F1 and its role in human disease. **Proteins and Expression Patterns:** POU5F1 is a highly conserved protein, with high sequence homology to other POU domain-containing proteins. It is expressed in embryonic stem cells, primordial germ cells, and certain types of cancer cells, where it maintains pluripotency and self-renewal. Its expression is also observed in granulocyte monocyte progenitor cells, retinal bipolar neurons, glandular epithelial cells, and certain types of intestinal epithelial cells. **Regulation and Interactions:** POU5F1 is regulated by various transcription factors, including SOX2, NANOG, and LEF1, which are involved in the maintenance of pluripotency and self-renewal. It also interacts with various proteins, including histone deacetylases (HDACs), which are involved in the regulation of gene expression. **Future Directions:** Further research is needed to fully elucidate the mechanisms of POU5F1 and its role in human disease. This includes the identification of novel interactions and regulatory pathways, as well as the development of therapeutic strategies targeting POU5F1 for the treatment of various diseases.

Genular Protein ID: 1091612296

Symbol: PO5F1_HUMAN

Name: POU domain, class 5, transcription factor 1

UniProtKB Accession Codes:

Q01860 A6NCS1 A6NLL8 D2IYK4 P31359 Q15167 Q15168 Q16422 Q5STF3 Q5STF4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CORUM 1 CTD 1 ChEBI 2 ChEMBL 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 2 ELM 1 EMBL 21 EMDB 10 Ensembl 13 ExpressionAtlas 1 GO 36 Gene3D 2 GeneCards 1 GeneTree 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 12 PDBsum 12 PIR 2 PRINTS 1 PRO 1 PROSITE 5 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 7 RefSeq 2 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1408763

Title: Human Oct3 gene family: cDNA sequences, alternative splicing, gene organization, chromosomal location, and expression at low levels in adult tissues.

PubMed ID: 1408763

DOI: 10.1093/nar/20.17.4613

PubMed ID: 20604894

Title: Comparison of MHC class I risk haplotypes in Thai and Caucasian psoriatics shows locus heterogeneity at PSORS1.

PubMed ID: 20604894

DOI: 10.1111/j.1399-0039.2010.01526.x

PubMed ID: 16702430

Title: Rapid evolution of major histocompatibility complex class I genes in primates generates new disease alleles in humans via hitchhiking diversity.

PubMed ID: 16702430

DOI: 10.1534/genetics.106.057034

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7908264

Title: A human POU domain gene, mPOU, is expressed in developing brain and specific adult tissues.

PubMed ID: 7908264

DOI: 10.1111/j.1432-1033.1994.tb18676.x

PubMed ID: 8567814

Title: Expression of transcription regulating genes in human preimplantation embryos.

PubMed ID: 8567814

DOI: 10.1093/oxfordjournals.humrep.a135792

PubMed ID: 16229821

Title: Oct4 pseudogenes are transcribed in cancers.

PubMed ID: 16229821

DOI: 10.1016/j.bbrc.2005.09.157

PubMed ID: 18035408

Title: Induction of pluripotent stem cells from adult human fibroblasts by defined factors.

PubMed ID: 18035408

DOI: 10.1016/j.cell.2007.11.019

PubMed ID: 18191611

Title: Pyruvate kinase isozyme type M2 (PKM2) interacts and cooperates with Oct-4 in regulating transcription.

PubMed ID: 18191611

DOI: 10.1016/j.biocel.2007.11.009

PubMed ID: 19274063

Title: WWP2 promotes degradation of transcription factor OCT4 in human embryonic stem cells.

PubMed ID: 19274063

DOI: 10.1038/cr.2009.31

PubMed ID: 23024368

Title: Serine 111 phosphorylation regulates OCT4A protein subcellular distribution and degradation.

PubMed ID: 23024368

DOI: 10.1074/jbc.m112.386755

PubMed ID: 22474382

Title: Phosphorylation regulates human OCT4.

PubMed ID: 22474382

DOI: 10.1073/pnas.1203874109

PubMed ID: 26687479

Title: The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

PubMed ID: 26687479

DOI: 10.1038/srep18388

PubMed ID: 34342803

Title: The 9aaTAD Activation Domains in the Yamanaka Transcription Factors Oct4, Sox2, Myc, and Klf4.

PubMed ID: 34342803

DOI: 10.1007/s12015-021-10225-8

Sequence Information:

  • Length: 360
  • Mass: 38571
  • Checksum: 934C58DAEA0C535B
  • Sequence:
    • MAGHLASDFA FSPPPGGGGD GPGGPEPGWV DPRTWLSFQG PPGGPGIGPG VGPGSEVWGI 
PPCPPPYEFC GGMAYCGPQV GVGLVPQGGL ETSQPEGEAG VGVESNSDGA SPEPCTVTPG 
AVKLEKEKLE QNPEESQDIK ALQKELEQFA KLLKQKRITL GYTQADVGLT LGVLFGKVFS 
QTTICRFEAL QLSFKNMCKL RPLLQKWVEE ADNNENLQEI CKAETLVQAR KRKRTSIENR 
VRGNLENLFL QCPKPTLQQI SHIAQQLGLE KDVVRVWFCN RRQKGKRSSS DYAQREDFEA 
AGSPFSGGPV SFPLAPGPHF GTPGYGSPHF TALYSSVPFP EGEAFPPVSV TTLGSPMHSN

Genular Protein ID: 3970452412

Symbol: M1S623_HUMAN

Name: N/A

UniProtKB Accession Codes:

M1S623 U3KQH6

Database IDs:

ARBA 7 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 8 Ensembl 2 GO 3 Gene3D 2 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 7 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 6 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 2 RuleBase 2 SMART 2 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 23990973

Title: An In-Depth Characterization of the Major Psoriasis Susceptibility Locus Identifies Candidate Susceptibility Alleles within an HLA-C Enhancer Element.

PubMed ID: 23990973

Sequence Information:

  • Length: 190
  • Mass: 21258
  • Checksum: E10B33910B06DABC
  • Sequence:
    • MGVLFGKVFS QTTICRFEAL QLSFKNMCKL RPLLQKWVEE ADNNENLQEI CKAETLVQAR 
KRKRTSIENR VRGNLENLFL QCPKPTLQQI SHIAQQLGLE KDVVRVWFCN RRQKGKRSSS 
DYAQREDFEA AGSPFSGGPV SFPLAPGPHF GTPGYGSPHF TALYSSVPFP EGEAFPPVSV 
TTLGSPMHSN

Genular Protein ID: 788906554

Symbol: F2Z381_HUMAN

Name: N/A

UniProtKB Accession Codes:

F2Z381

Database IDs:

ARBA 7 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 9 Ensembl 5 GO 3 Gene3D 2 GeneTree 1 HGNC 1 InterPro 7 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 5 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 RuleBase 1 SMART 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

Sequence Information:

  • Length: 164
  • Mass: 18311
  • Checksum: F7118F4DE7DEBDD6
  • Sequence:
    • MCKLRPLLQK WVEEADNNEN LQEICKAETL VQARKRKRTS IENRVRGNLE NLFLQCPKPT 
LQQISHIAQQ LGLEKDVVRV WFCNRRQKGK RSSSDYAQRE DFEAAGSPFS GGPVSFPLAP 
GPHFGTPGYG SPHFTALYSS VPFPEGEAFP PVSVTTLGSP MHSN

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.