Details for: PRG2

Gene ID: 5553

Symbol: PRG2

Ensembl ID: ENSG00000186652

Description: proteoglycan 2, pro eosinophil major basic protein

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 7.2648
    Cell Significance Index: -1.1300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 5.2436
    Cell Significance Index: -1.3300
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 4.4870
    Cell Significance Index: 27.8800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 1.0949
    Cell Significance Index: -1.3500
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 0.2281
    Cell Significance Index: 1.8600
  • Cell Name: basophil mast progenitor cell (CL0002028)
    Fold Change: 0.2216
    Cell Significance Index: 1.8700
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: 0.2043
    Cell Significance Index: 2.6400
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.0928
    Cell Significance Index: 2.6600
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.0728
    Cell Significance Index: 0.4400
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: 0.0474
    Cell Significance Index: 0.5100
  • Cell Name: suprabasal keratinocyte (CL4033013)
    Fold Change: 0.0404
    Cell Significance Index: 0.6500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0382
    Cell Significance Index: 1.0200
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: 0.0341
    Cell Significance Index: 0.3300
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: 0.0314
    Cell Significance Index: 0.4500
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.0256
    Cell Significance Index: 1.2900
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 0.0195
    Cell Significance Index: 0.1400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0054
    Cell Significance Index: 0.6900
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0009
    Cell Significance Index: -0.0400
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.0012
    Cell Significance Index: -0.0200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0020
    Cell Significance Index: -1.4500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0020
    Cell Significance Index: -1.5000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0024
    Cell Significance Index: -1.3500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0037
    Cell Significance Index: -0.5100
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: -0.0064
    Cell Significance Index: -0.0900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0064
    Cell Significance Index: -1.2900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0064
    Cell Significance Index: -1.0900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0065
    Cell Significance Index: -1.1800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0073
    Cell Significance Index: -0.8400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0077
    Cell Significance Index: -1.5200
  • Cell Name: eosinophil (CL0000771)
    Fold Change: -0.0079
    Cell Significance Index: -0.0700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0090
    Cell Significance Index: -1.0500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0114
    Cell Significance Index: -0.3100
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0115
    Cell Significance Index: -0.4700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0118
    Cell Significance Index: -1.5200
  • Cell Name: perivascular cell (CL4033054)
    Fold Change: -0.0130
    Cell Significance Index: -0.0600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0137
    Cell Significance Index: -1.4000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0139
    Cell Significance Index: -0.6500
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.0153
    Cell Significance Index: -0.4100
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: -0.0158
    Cell Significance Index: -0.1500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0162
    Cell Significance Index: -1.2400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0164
    Cell Significance Index: -1.0100
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: -0.0178
    Cell Significance Index: -0.2300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0181
    Cell Significance Index: -0.8500
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: -0.0186
    Cell Significance Index: -0.2700
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.0190
    Cell Significance Index: -0.4600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0220
    Cell Significance Index: -1.6400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0223
    Cell Significance Index: -1.2500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0237
    Cell Significance Index: -1.5300
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: -0.0237
    Cell Significance Index: -0.3400
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: -0.0253
    Cell Significance Index: -0.3200
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: -0.0262
    Cell Significance Index: -0.2700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0262
    Cell Significance Index: -0.7300
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: -0.0283
    Cell Significance Index: -0.3200
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: -0.0294
    Cell Significance Index: -0.4300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0299
    Cell Significance Index: -0.8000
  • Cell Name: trophoblast giant cell (CL0002488)
    Fold Change: -0.0333
    Cell Significance Index: -0.2400
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.0334
    Cell Significance Index: -0.3800
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0353
    Cell Significance Index: -0.9000
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.0356
    Cell Significance Index: -0.7100
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: -0.0364
    Cell Significance Index: -0.5300
  • Cell Name: immature B cell (CL0000816)
    Fold Change: -0.0365
    Cell Significance Index: -0.3500
  • Cell Name: L4 intratelencephalic projecting glutamatergic neuron (CL4030063)
    Fold Change: -0.0374
    Cell Significance Index: -0.4100
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.0376
    Cell Significance Index: -1.3800
  • Cell Name: blood vessel endothelial cell (CL0000071)
    Fold Change: -0.0377
    Cell Significance Index: -0.4100
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: -0.0399
    Cell Significance Index: -0.4700
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.0419
    Cell Significance Index: -0.8200
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0422
    Cell Significance Index: -1.3800
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.0424
    Cell Significance Index: -1.0600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0433
    Cell Significance Index: -1.3800
  • Cell Name: granulocyte (CL0000094)
    Fold Change: -0.0444
    Cell Significance Index: -0.5400
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.0444
    Cell Significance Index: -1.1100
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.0446
    Cell Significance Index: -0.7500
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0452
    Cell Significance Index: -1.1600
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.0489
    Cell Significance Index: -0.6500
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: -0.0493
    Cell Significance Index: -0.6100
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: -0.0497
    Cell Significance Index: -0.8100
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.0500
    Cell Significance Index: -0.7100
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.0505
    Cell Significance Index: -0.8700
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.0518
    Cell Significance Index: -1.5200
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.0520
    Cell Significance Index: -0.6800
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0529
    Cell Significance Index: -1.3200
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: -0.0537
    Cell Significance Index: -0.6900
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0546
    Cell Significance Index: -1.3100
  • Cell Name: promonocyte (CL0000559)
    Fold Change: -0.0562
    Cell Significance Index: -0.6000
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.0563
    Cell Significance Index: -1.3000
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0579
    Cell Significance Index: -1.1300
  • Cell Name: erythroblast (CL0000765)
    Fold Change: -0.0587
    Cell Significance Index: -0.7000
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0592
    Cell Significance Index: -1.2800
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -0.0596
    Cell Significance Index: -0.8000
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.0623
    Cell Significance Index: -1.0000
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0627
    Cell Significance Index: -1.3300
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: -0.0635
    Cell Significance Index: -0.9500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0648
    Cell Significance Index: -1.0900
  • Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
    Fold Change: -0.0652
    Cell Significance Index: -0.7200
  • Cell Name: mast cell (CL0000097)
    Fold Change: -0.0653
    Cell Significance Index: -0.8600
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0662
    Cell Significance Index: -1.4500
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0668
    Cell Significance Index: -1.3200
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: -0.0671
    Cell Significance Index: -0.7500
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: -0.0673
    Cell Significance Index: -1.1500
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0682
    Cell Significance Index: -1.3700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Structure**: PRG2 consists of a core protein and a heavily glycosylated glycosaminoglycan chain, which confers unique properties to this molecule. 2. **Expression**: PRG2 is significantly expressed in various cell types, including endothelial cells, neurons, and hematopoietic cells. 3. **Function**: PRG2 is involved in immune response, cell signaling, and tissue development. 4. **Glycosylation**: The glycosaminoglycan chain of PRG2 is heavily glycosylated, which is essential for its biological activity. **Pathways and Functions** PRG2 is involved in various biological pathways, including: 1. **Immune Response**: PRG2 is involved in the regulation of immune responses, including the modulation of cytokine production and the regulation of neutrophil degranulation. 2. **Cell Signaling**: PRG2 acts as a signaling molecule, influencing cell growth, differentiation, and survival. 3. **Tissue Development**: PRG2 is involved in the development and maintenance of various tissues, including the endothelial system and the nervous system. 4. **Neurotransmission**: PRG2 is expressed in GABAergic interneurons and plays a role in neurotransmission. **Clinical Significance** PRG2 has been implicated in various diseases and disorders, including: 1. **Allergic Disorders**: PRG2 is involved in the regulation of eosinophilic inflammation, which is a hallmark of allergic disorders. 2. **Cardiovascular Diseases**: PRG2 is expressed in endothelial cells and is involved in the regulation of vascular tone and blood pressure. 3. **Neurological Disorders**: PRG2 is expressed in neurons and is involved in the regulation of neurotransmission and synaptic plasticity. 4. **Cancer**: PRG2 is overexpressed in various types of cancer, including leukemia and lymphoma. In conclusion, PRG2 is a multifunctional protein that plays a crucial role in various biological processes, including immune response, cell signaling, and tissue development. Its dysregulation has been implicated in various diseases and disorders, highlighting the importance of further research into the functions and mechanisms of PRG2.

Genular Protein ID: 3528652865

Symbol: PRG2_HUMAN

Name: Bone marrow proteoglycan

UniProtKB Accession Codes:

P13727 A6XMW0 B2R5I1 P81448 Q14227 Q6ICT2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CORUM 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 2 EMBL 12 EMDB 2 Ensembl 3 EvolutionaryTrace 1 GO 14 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MEROPS 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 5 PDBsum 5 PIR 1 PRINTS 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 4 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TopDownProteomics 1 TreeFam 1 UCSC 1 UniLectin 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 3171483

Title: Acidic precursor revealed in human eosinophil granule major basic protein cDNA.

PubMed ID: 3171483

DOI: 10.1084/jem.168.4.1493

PubMed ID: 2323577

Title: Cloning and sequence analysis of the human gene encoding eosinophil major basic protein.

PubMed ID: 2323577

DOI: 10.1016/0378-1119(90)90292-y

PubMed ID: 3199069

Title: Isolation of a complementary DNA clone encoding a precursor to human eosinophil major basic protein.

PubMed ID: 3199069

DOI: 10.1084/jem.168.6.2295

PubMed ID: 1565101

Title: Purification and cDNA cloning of a novel factor produced by a human T-cell hybridoma: sequence homology with animal lectins.

PubMed ID: 1565101

DOI: 10.1016/0161-5890(92)90012-m

PubMed ID: 7531438

Title: Human eosinophil major basic protein, a mediator of allergic inflammation, is expressed by alternative splicing from two promoters.

PubMed ID: 7531438

DOI: 10.1042/bj3050921

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8507662

Title: Pro-major basic protein has three types of sugar chains at the pro-portion.

PubMed ID: 8507662

DOI: 10.1016/0167-4838(93)90158-n

PubMed ID: 7685339

Title: Circulating human pregnancy-associated plasma protein-A is disulfide-bridged to the proform of eosinophil major basic protein.

PubMed ID: 7685339

DOI: 10.1016/s0021-9258(18)31378-4

PubMed ID: 7539791

Title: Identification of angiotensinogen and complement C3dg as novel proteins binding the proform of eosinophil major basic protein in human pregnancy serum and plasma.

PubMed ID: 7539791

DOI: 10.1074/jbc.270.23.13645

PubMed ID: 3410852

Title: Biochemical and amino acid sequence analysis of human eosinophil granule major basic protein.

PubMed ID: 3410852

DOI: 10.1016/s0021-9258(18)37791-3

PubMed ID: 2501794

Title: Antibiotic proteins of human polymorphonuclear leukocytes.

PubMed ID: 2501794

DOI: 10.1073/pnas.86.14.5610

PubMed ID: 3422083

Title: Eosinophil granule cationic proteins: major basic protein is distinct from the smaller subunit of eosinophil peroxidase.

PubMed ID: 3422083

DOI: 10.1002/jlb.43.1.1

PubMed ID: 7508748

Title: Amino acid sequence of human pregnancy-associated plasma protein-A derived from cloned cDNA.

PubMed ID: 7508748

DOI: 10.1021/bi00172a040

PubMed ID: 2584934

Title: Evidence of eosinophil granule major basic protein in human placenta.

PubMed ID: 2584934

DOI: 10.1084/jem.170.6.2051

PubMed ID: 7524900

Title: Location and nature of carbohydrate groups in proform of human major basic protein isolated from pregnancy serum.

PubMed ID: 7524900

PubMed ID: 8137941

Title: Localization of disulfide bridges and free sulfhydryl groups in human eosinophil granule major basic protein.

PubMed ID: 8137941

DOI: 10.1016/0014-5793(94)80459-1

PubMed ID: 7526035

Title: Localization of pregnancy-associated plasma protein-A and colocalization of pregnancy-associated plasma protein-A messenger ribonucleic acid and eosinophil granule major basic protein messenger ribonucleic acid in placenta.

PubMed ID: 7526035

PubMed ID: 10491647

Title: Messenger ribonucleic acid levels of pregnancy-associated plasma protein-A and the proform of eosinophil major basic protein: expression in human reproductive and nonreproductive tissues.

PubMed ID: 10491647

DOI: 10.1095/biolreprod61.4.1083

PubMed ID: 10913121

Title: Expression of recombinant human pregnancy-associated plasma protein-A and identification of the proform of eosinophil major basic protein as its physiological inhibitor.

PubMed ID: 10913121

DOI: 10.1074/jbc.m001384200

PubMed ID: 12421832

Title: Complex of pregnancy-associated plasma protein-A and the proform of eosinophil major basic protein. Disulfide structure and carbohydrate attachment sites.

PubMed ID: 12421832

DOI: 10.1074/jbc.m208777200

PubMed ID: 18694936

Title: Post-translational tyrosine nitration of eosinophil granule toxins mediated by eosinophil peroxidase.

PubMed ID: 18694936

DOI: 10.1074/jbc.m801196200

PubMed ID: 25326458

Title: Identification of chondroitin sulfate linkage region glycopeptides reveals prohormones as a novel class of proteoglycans.

PubMed ID: 25326458

DOI: 10.1074/mcp.m114.043703

PubMed ID: 32337544

Title: An affinity chromatography and glycoproteomics workflow to profile the chondroitin sulfate proteoglycans that interact with malarial VAR2CSA in the placenta and in cancer.

PubMed ID: 32337544

DOI: 10.1093/glycob/cwaa039

PubMed ID: 36213313

Title: Mass spectrometric analysis of chondroitin sulfate-linked peptides.

PubMed ID: 36213313

DOI: 10.1007/s42485-022-00092-3

PubMed ID: 37453717

Title: Mapping the Human Chondroitin Sulfate Glycoproteome Reveals an Unexpected Correlation Between Glycan Sulfation and Attachment Site Characteristics.

PubMed ID: 37453717

DOI: 10.1016/j.mcpro.2023.100617

PubMed ID: 11319227

Title: Crystal structure of the eosinophil major basic protein at 1.8-A. An atypical lectin with a paradigm shift in specificity.

PubMed ID: 11319227

DOI: 10.1074/jbc.m100848200

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 222
  • Mass: 25206
  • Checksum: CDD545642555E2D0
  • Sequence:
    • MKLPLLLALL FGAVSALHLR SETSTFETPL GAKTLPEDEE TPEQEMEETP CRELEEEEEW 
GSGSEDASKK DGAVESISVP DMVDKNLTCP EEEDTVKVVG IPGCQTCRYL LVRSLQTFSQ 
AWFTCRRCYR GNLVSIHNFN INYRIQCSVS ALNQGQVWIG GRITGSGRCR RFQWVDGSRW 
NFAYWAAHQP WSRGGHCVAL CTRGGHWRRA HCLRRLPFIC SY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.