Details for: PKIB
Gene ID: 5570
Gene Type: Protein-coding - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.
Symbol: PKIB
Ensembl ID: ENSG00000135549
Description: cAMP-dependent protein kinase inhibitor beta
Cell Significance Landscape
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
-
CSI 34.1rCSI 33.53%PRS 78.65
-
CSI 33rCSI 50.99%PRS 74.98
-
CSI 22.77rCSI 33.48%PRS 68.57
-
CSI 22.57rCSI 23.64%PRS 73.1
-
CSI 17.08rCSI 49.19%PRS 83.64
-
CSI 16.2rCSI 24.74%PRS 87.86
-
CSI 14.15rCSI 30.11%PRS 83.31
-
CSI 13.16rCSI 29.14%PRS 74.89
-
CSI 12.37rCSI 14.94%PRS 84
-
CSI 12.37rCSI 16.9%PRS 76.34
-
CSI 11.84rCSI 12.38%PRS 73.68
-
CSI 10.97rCSI 19.82%PRS 82.79
-
CSI 9.66rCSI 34.29%PRS 81.18
-
CSI 9.3rCSI 21.47%PRS 63.79
-
CSI 9.27rCSI 48.67%PRS 82.67
-
CSI 9.22rCSI 17.27%PRS 63.76
-
CSI 8.75rCSI 9.13%PRS 75.49
-
CSI 8.73rCSI 40.71%PRS 86.47
-
CSI 8.71rCSI 6.45%PRS 68.82
-
CSI 8.28rCSI 13.36%PRS 75.84
-
CSI 8.08rCSI 11.95%PRS 80.52
-
CSI 7.72rCSI 7.29%PRS 75
-
CSI 7.49rCSI 17.86%PRS 73.89
-
CSI 7.33rCSI 6.5%PRS 73.8
-
CSI 7.26rCSI 8.42%PRS 80.59
-
CSI 6.85rCSI 27.28%PRS 84.57
-
CSI 6.66rCSI 14.66%PRS 84.99
-
CSI 6.64rCSI 7.68%PRS 67.54
-
CSI 6.63rCSI 8.51%PRS 72.22
-
CSI 6.27rCSI 9.32%PRS 76.38
-
CSI 6.25rCSI 9.22%PRS 87.41
-
CSI 6.08rCSI 5.86%PRS 68.47
-
CSI 5.9rCSI 12.99%PRS 79.96
-
CSI 5.77rCSI 7.71%PRS 82.72
-
CSI 5.68rCSI 8.22%PRS 89.01
-
CSI 5.67rCSI 9.12%PRS 65.65
-
CSI 5.62rCSI 9.11%PRS 71.22
-
CSI 5.48rCSI 12.54%PRS 76.68
-
CSI 5.28rCSI 6.51%PRS 81.79
-
CSI 5.28rCSI 13.06%PRS 75.21
-
CSI 5.21rCSI 7.23%PRS 74.57
-
CSI 5.1rCSI 4.71%PRS 77.51
-
CSI 5.02rCSI 10.09%PRS 65.49
-
CSI 4.99rCSI 15.62%PRS 61.47
-
CSI 4.83rCSI 26%PRS 84.27
-
CSI 4.68rCSI 6.86%PRS 70.58
-
CSI 4.64rCSI 4.86%PRS 79.1
-
CSI 4.63rCSI 3.66%PRS 63.8
-
CSI 4.46rCSI 5.55%PRS 55.21
-
CSI 4.39rCSI 5.15%PRS 77.81
-
CSI 4.32rCSI 4.59%PRS 82.01
-
CSI 4.2rCSI 4.19%PRS 69.56
-
CSI 4.12rCSI 9.83%PRS 76.06
-
CSI 3.92rCSI 6%PRS 85.45
-
CSI 3.82rCSI 8.56%PRS 58
-
CSI 3.79rCSI 27.85%PRS 62.7
-
CSI 3.73rCSI 7.26%PRS 79.14
-
CSI 3.7rCSI 5.88%PRS 85.18
-
CSI 3.68rCSI 8.07%PRS 82
-
CSI 3.64rCSI 4.69%PRS 58.52
-
CSI 3.55rCSI 3.12%PRS 81.15
-
CSI 3.43rCSI 18.68%PRS 85.48
-
CSI 3.37rCSI 7.69%PRS 70.13
-
CSI 3.37rCSI 6.69%PRS 71.96
-
CSI 3.31rCSI 5.83%PRS 71.79
-
CSI 3.23rCSI 4%PRS 73.57
-
CSI 3.05rCSI 4.69%PRS 84.94
-
CSI 3.04rCSI 17.09%PRS 90.96
-
CSI 3rCSI 8.9%PRS 84.84
-
CSI 2.84rCSI 13.12%PRS 89.15
-
CSI 2.81rCSI 6.14%PRS 84.22
-
CSI 2.56rCSI 9.69%PRS 57.67
-
CSI 2.52rCSI 3.36%PRS 74.8
-
CSI 2.51rCSI 2.99%PRS 57.22
-
CSI 2.51rCSI 5.53%PRS 61.33
-
CSI 2.47rCSI 3.38%PRS 67.79
-
CSI 2.37rCSI 2.85%PRS 73.88
-
CSI 2.24rCSI 2.81%PRS 85.19
-
CSI 2.21rCSI 3.17%PRS 77.44
-
CSI 2.18rCSI 4.09%PRS 84.9
-
CSI 2.18rCSI 2.89%PRS 81.85
-
CSI 2.03rCSI 6.88%PRS 75.04
-
CSI 1.93rCSI 5.2%PRS 81.43
-
CSI 1.87rCSI 20.36%PRS 85.5
-
CSI 1.86rCSI 2.54%PRS 79.29
-
CSI 1.76rCSI 1.55%PRS 64.51
-
CSI 1.72rCSI 3.04%PRS 56.48
-
CSI 1.67rCSI 3.04%PRS 87.08
-
CSI 1.66rCSI 5.18%PRS 59.02
-
CSI 1.65rCSI 10.15%PRS 83.55
-
CSI 1.62rCSI 4.18%PRS 70.92
-
CSI 1.5rCSI 1.87%PRS 77.14
-
CSI 1.39rCSI 28.29%PRS 66.8
-
CSI 1.27rCSI 2.04%PRS 58.96
-
CSI 1.25rCSI 3.57%PRS 83.86
-
CSI 1.16rCSI 4.06%PRS 85.02
-
CSI 1.15rCSI 2.92%PRS 69.45
-
CSI 1.14rCSI 1.18%PRS 80.61
-
CSI 1.14rCSI 1.91%PRS 57.25
-
CSI 1.08rCSI 10.67%PRS 87.95
-
CSI 0.3rCSI 6.9%PRS 65.5%
-
CSI 0.4rCSI 5.5%PRS 85.7%
-
CSI 0.4rCSI 2.4%PRS 58.1%
-
CSI 0.5rCSI 6.0%PRS 86.8%
-
CSI 0.8rCSI 3.5%PRS 86.4%
-
CSI 0.8rCSI 3.1%PRS 85.4%
-
CSI 0.8rCSI 1.9%PRS 82.5%
-
CSI 0.8rCSI 2.9%PRS 55.3%
-
CSI 0.9rCSI 1.7%PRS 84.8%
-
CSI 1.0rCSI 3.8%PRS 86.1%
-
CSI 1.1rCSI 1.6%PRS 80.0%
-
CSI 1.1rCSI 10.7%PRS 88.0%
-
CSI 1.1rCSI 1.9%PRS 57.3%
-
CSI 1.1rCSI 1.2%PRS 80.6%
-
CSI 1.2rCSI 2.9%PRS 69.5%
-
CSI 1.2rCSI 4.1%PRS 85.0%
-
CSI 1.3rCSI 3.6%PRS 83.9%
-
CSI 1.3rCSI 2.0%PRS 59.0%
-
CSI 1.4rCSI 28.3%PRS 66.8%
-
CSI 1.5rCSI 1.9%PRS 77.1%
-
CSI 1.6rCSI 4.2%PRS 70.9%
-
CSI 1.7rCSI 10.2%PRS 83.6%
-
CSI 1.7rCSI 5.2%PRS 59.0%
-
CSI 1.7rCSI 3.0%PRS 87.1%
-
CSI 1.7rCSI 3.0%PRS 56.5%
-
CSI 1.8rCSI 1.6%PRS 64.5%
-
CSI 1.9rCSI 2.5%PRS 79.3%
-
CSI 1.9rCSI 20.4%PRS 85.5%
-
CSI 1.9rCSI 5.2%PRS 81.4%
-
CSI 2.0rCSI 6.9%PRS 75.0%
-
CSI 2.2rCSI 2.9%PRS 81.9%
-
CSI 2.2rCSI 4.1%PRS 84.9%
-
CSI 2.2rCSI 3.2%PRS 77.4%
-
CSI 2.2rCSI 2.8%PRS 85.2%
-
CSI 2.4rCSI 2.9%PRS 73.9%
-
CSI 2.5rCSI 3.4%PRS 67.8%
-
CSI 2.5rCSI 5.5%PRS 61.3%
-
CSI 2.5rCSI 3.0%PRS 57.2%
-
CSI 2.5rCSI 3.4%PRS 74.8%
-
CSI 2.6rCSI 9.7%PRS 57.7%
-
CSI 2.8rCSI 6.1%PRS 84.2%
-
CSI 2.8rCSI 13.1%PRS 89.2%
-
CSI 3.0rCSI 8.9%PRS 84.8%
-
CSI 3.0rCSI 17.1%PRS 91.0%
-
CSI 3.1rCSI 4.7%PRS 84.9%
-
CSI 3.2rCSI 4.0%PRS 73.6%
-
CSI 3.3rCSI 5.8%PRS 71.8%
-
CSI 3.4rCSI 6.7%PRS 72.0%
-
CSI 3.4rCSI 7.7%PRS 70.1%
-
CSI 3.4rCSI 18.7%PRS 85.5%
-
CSI 3.6rCSI 3.1%PRS 81.2%
-
CSI 3.6rCSI 4.7%PRS 58.5%
-
CSI 3.7rCSI 8.1%PRS 82.0%
-
CSI 3.7rCSI 5.9%PRS 85.2%
-
CSI 3.7rCSI 7.3%PRS 79.1%
-
CSI 3.8rCSI 27.9%PRS 62.7%
-
CSI 3.8rCSI 8.6%PRS 58.0%
-
CSI 3.9rCSI 6.0%PRS 85.5%
-
CSI 4.1rCSI 9.8%PRS 76.1%
-
CSI 4.2rCSI 4.2%PRS 69.6%
-
CSI 4.3rCSI 4.6%PRS 82.0%
-
CSI 4.4rCSI 5.2%PRS 77.8%
-
CSI 4.5rCSI 5.6%PRS 55.2%
-
CSI 4.6rCSI 3.7%PRS 63.8%
-
CSI 4.6rCSI 4.9%PRS 79.1%
-
CSI 4.7rCSI 6.9%PRS 70.6%
-
CSI 4.8rCSI 26.0%PRS 84.3%
-
CSI 5.0rCSI 15.6%PRS 61.5%
-
CSI 5.0rCSI 10.1%PRS 65.5%
-
CSI 5.1rCSI 4.7%PRS 77.5%
-
CSI 5.2rCSI 7.2%PRS 74.6%
-
CSI 5.3rCSI 13.1%PRS 75.2%
-
CSI 5.3rCSI 6.5%PRS 81.8%
-
CSI 5.5rCSI 12.5%PRS 76.7%
-
CSI 5.6rCSI 9.1%PRS 71.2%
-
CSI 5.7rCSI 9.1%PRS 65.7%
-
CSI 5.7rCSI 8.2%PRS 89.0%
-
CSI 5.8rCSI 7.7%PRS 82.7%
-
CSI 5.9rCSI 13.0%PRS 80.0%
-
CSI 6.1rCSI 5.9%PRS 68.5%
-
CSI 6.3rCSI 9.2%PRS 87.4%
-
CSI 6.3rCSI 9.3%PRS 76.4%
-
CSI 6.6rCSI 8.5%PRS 72.2%
-
CSI 6.6rCSI 7.7%PRS 67.5%
-
CSI 6.7rCSI 14.7%PRS 85.0%
-
CSI 6.9rCSI 27.3%PRS 84.6%
-
CSI 7.3rCSI 8.4%PRS 80.6%
-
CSI 7.3rCSI 6.5%PRS 73.8%
-
CSI 7.5rCSI 17.9%PRS 73.9%
-
CSI 7.7rCSI 7.3%PRS 75.0%
-
CSI 8.1rCSI 12.0%PRS 80.5%
-
CSI 8.3rCSI 13.4%PRS 75.8%
-
CSI 8.7rCSI 6.5%PRS 68.8%
-
CSI 8.7rCSI 40.7%PRS 86.5%
-
CSI 8.8rCSI 9.1%PRS 75.5%
-
CSI 9.2rCSI 17.3%PRS 63.8%
-
CSI 9.3rCSI 48.7%PRS 82.7%
-
CSI 9.3rCSI 21.5%PRS 63.8%
-
CSI 9.7rCSI 34.3%PRS 81.2%
-
CSI 11.0rCSI 19.8%PRS 82.8%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Comma-separated if multiple.
Comma-separated if multiple.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Disclaimer: This in-silico analysis is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.
Genular Protein ID: 1901204747
Symbol: IPKB_HUMAN
Name: cAMP-dependent protein kinase inhibitor beta
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10880337
Title: Cloning and mapping of human PKIB and PKIG, and comparison of tissue expression patterns of three members of the protein kinase inhibitor family, including PKIA.
PubMed ID: 10880337
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 78
- Mass: 8468
- Checksum: CA4AE267B9ECCD81
- Sequence:
MRTDSSKMTD VESGVANFAS SARAGRRNAL PDIQSSAATD GTSDLPLKLE ALSVKEDAKE KDEKTTQDQL EKPQNEEK