Details for: PTPN13

Gene ID: 5783

Symbol: PTPN13

Ensembl ID: ENSG00000163629

Description: protein tyrosine phosphatase non-receptor type 13

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 438.2970
    Cell Significance Index: -68.1800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 269.1180
    Cell Significance Index: -68.2600
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 138.7563
    Cell Significance Index: -65.5100
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 122.7548
    Cell Significance Index: -49.8700
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 52.0140
    Cell Significance Index: -49.6600
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 17.2527
    Cell Significance Index: -68.0800
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 12.7993
    Cell Significance Index: 152.5800
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 11.0848
    Cell Significance Index: -24.2600
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 6.4673
    Cell Significance Index: 138.2400
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 4.2742
    Cell Significance Index: 83.4200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 3.9399
    Cell Significance Index: 248.3200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 3.7461
    Cell Significance Index: 104.6900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 3.2560
    Cell Significance Index: 182.7100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.9185
    Cell Significance Index: 345.8500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 1.9059
    Cell Significance Index: 128.1600
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 1.6889
    Cell Significance Index: 23.7200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.5028
    Cell Significance Index: 301.4600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.3901
    Cell Significance Index: 170.9200
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 1.3677
    Cell Significance Index: 39.0300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.1687
    Cell Significance Index: 60.7100
  • Cell Name: epidermal cell (CL0000362)
    Fold Change: 1.1444
    Cell Significance Index: 2.5800
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.9856
    Cell Significance Index: 14.0300
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.7173
    Cell Significance Index: 6.6100
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: 0.6202
    Cell Significance Index: 7.8100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.6144
    Cell Significance Index: 1156.8800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.5823
    Cell Significance Index: 402.7600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.5526
    Cell Significance Index: 198.2100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.4879
    Cell Significance Index: 440.5400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.4817
    Cell Significance Index: 21.3100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.3915
    Cell Significance Index: 53.7600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.3745
    Cell Significance Index: 37.0500
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.3252
    Cell Significance Index: 4.6700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 0.3205
    Cell Significance Index: 200.1600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.2555
    Cell Significance Index: 162.2400
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.1684
    Cell Significance Index: 27.3900
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 0.1282
    Cell Significance Index: 1.9500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1016
    Cell Significance Index: 44.9400
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.0864
    Cell Significance Index: 3.2700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0821
    Cell Significance Index: 44.8600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0735
    Cell Significance Index: 113.0900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0732
    Cell Significance Index: 33.2100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0534
    Cell Significance Index: 98.4500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0366
    Cell Significance Index: 0.9200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0024
    Cell Significance Index: -3.2400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0084
    Cell Significance Index: -6.3500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0109
    Cell Significance Index: -8.0300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0114
    Cell Significance Index: -1.6500
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0115
    Cell Significance Index: -0.7100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0222
    Cell Significance Index: -0.7800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0308
    Cell Significance Index: -22.8200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0531
    Cell Significance Index: -1.5300
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0579
    Cell Significance Index: -0.7900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0878
    Cell Significance Index: -49.5300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.1077
    Cell Significance Index: -11.7200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.1365
    Cell Significance Index: -17.5000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1571
    Cell Significance Index: -9.6600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.1652
    Cell Significance Index: -7.4900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1666
    Cell Significance Index: -47.9500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2001
    Cell Significance Index: -42.1600
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.2065
    Cell Significance Index: -10.4400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.2366
    Cell Significance Index: -40.4100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2575
    Cell Significance Index: -26.8100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.2817
    Cell Significance Index: -55.9100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2996
    Cell Significance Index: -34.9100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.4745
    Cell Significance Index: -61.3000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.4858
    Cell Significance Index: -10.5300
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.5123
    Cell Significance Index: -52.3300
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.5150
    Cell Significance Index: -58.7900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.5467
    Cell Significance Index: -64.4700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.5480
    Cell Significance Index: -62.7800
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.5720
    Cell Significance Index: -8.8500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.6279
    Cell Significance Index: -20.1100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.6711
    Cell Significance Index: -50.0200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.6741
    Cell Significance Index: -53.3900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.6746
    Cell Significance Index: -46.6500
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: -0.6808
    Cell Significance Index: -9.5200
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.8044
    Cell Significance Index: -5.4500
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.8198
    Cell Significance Index: -17.4000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.8468
    Cell Significance Index: -44.1100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.8511
    Cell Significance Index: -65.3100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.8764
    Cell Significance Index: -56.5400
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.8774
    Cell Significance Index: -15.1700
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.8949
    Cell Significance Index: -63.2900
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.8957
    Cell Significance Index: -18.5800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -1.0782
    Cell Significance Index: -50.6800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -1.3059
    Cell Significance Index: -45.3800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -1.3161
    Cell Significance Index: -69.1000
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -1.3286
    Cell Significance Index: -27.7300
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -1.3319
    Cell Significance Index: -46.6600
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -1.3628
    Cell Significance Index: -40.1400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -1.4031
    Cell Significance Index: -38.1900
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -1.4191
    Cell Significance Index: -40.6800
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -1.4249
    Cell Significance Index: -45.3800
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -1.4710
    Cell Significance Index: -18.2500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -1.4911
    Cell Significance Index: -24.9600
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -1.5228
    Cell Significance Index: -36.5200
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -1.5481
    Cell Significance Index: -56.8300
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -1.5509
    Cell Significance Index: -38.6900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -1.6037
    Cell Significance Index: -34.1600
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -1.6222
    Cell Significance Index: -35.5200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** PTPN13 is a member of the protein tyrosine phosphatase (PTP) family, which is characterized by the ability to remove phosphate groups from tyrosine residues on proteins. PTPN13 is a non-receptor PTP, meaning it lacks a transmembrane domain and is anchored to the cytoskeleton. It is a dual-specificity PTP, capable of dephosphorylating both phosphotyrosine and phosphoserine/threonine residues. **Pathways and Functions** PTPN13 is involved in various signaling pathways, including: 1. **PI3K/AKT signaling**: PTPN13 regulates the activity of PI3K, a key enzyme in the PI3K/AKT signaling pathway. This pathway is involved in cell survival, proliferation, and differentiation. 2. **JAK/STAT signaling**: PTPN13 dephosphorylates and inactivates Janus kinase (JAK) proteins, which are essential for the activation of transcription factors in the JAK/STAT signaling pathway. 3. **Cytokine signaling**: PTPN13 regulates the activity of cytokine receptors, including those involved in immune responses such as interleukin-1 (IL-1) and interleukin-37 (IL-37) signaling. 4. **Metabolic regulation**: PTPN13 is involved in the regulation of lipid metabolism, including the synthesis and degradation of phosphatidylinositol 3,4,5-trisphosphate (PIP3). **Clinical Significance** Dysregulation of PTPN13 has been implicated in various diseases, including: 1. **Immune disorders**: Mutations in PTPN13 have been associated with autoimmune diseases such as rheumatoid arthritis and lupus. 2. **Cancer**: Overexpression of PTPN13 has been observed in certain types of cancer, including breast cancer and leukemia. 3. **Neurological disorders**: PTPN13 has been implicated in the pathogenesis of neurological disorders such as schizophrenia and bipolar disorder. 4. **Metabolic disorders**: Dysregulation of PTPN13 has been linked to metabolic disorders such as obesity and insulin resistance. In summary, PTPN13 is a non-receptor tyrosine phosphatase that plays a critical role in various cellular processes, including immune response, cell signaling, and metabolic regulation. Its dysregulation has been implicated in various diseases, highlighting the importance of PTPN13 in maintaining cellular homeostasis.

Genular Protein ID: 153609471

Symbol: PTN13_HUMAN

Name: Tyrosine-protein phosphatase non-receptor type 13

UniProtKB Accession Codes:

Q12923 B2RTR0 Q15159 Q15263 Q15264 Q15265 Q15674 Q16826 Q8IWH7 Q9NYN9 Q9UDA8

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 4 CTD 1 ChEBI 4 ChEMBL 1 ChiTaRS 1 DEPOD 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EC 1 ELM 1 EMBL 10 Ensembl 5 EvolutionaryTrace 1 ExpressionAtlas 1 GO 18 Gene3D 5 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 18 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 12 PDBsum 12 PIR 3 PIRSF 1 PRINTS 2 PRO 1 PROSITE 5 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 6 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 Reactome 5 RefSeq 4 Rhea 3 SIGNOR 1 SMART 6 SMR 1 STRING 1 SUPFAM 5 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8071359

Title: A novel protein-tyrosine phosphatase with homology to both the cytoskeletal proteins of the band 4.1 family and junction-associated guanylate kinases.

PubMed ID: 8071359

DOI: 10.1016/s0021-9258(17)31792-1

PubMed ID: 8287977

Title: Molecular cloning of a novel protein-tyrosine phosphatase containing a membrane-binding domain and GLGF repeats.

PubMed ID: 8287977

DOI: 10.1016/0014-5793(94)80273-4

PubMed ID: 7929060

Title: Cloning and characterization of PTPL1, a protein tyrosine phosphatase with similarities to cytoskeletal-associated proteins.

PubMed ID: 7929060

DOI: 10.1016/s0021-9258(19)51050-x

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7536343

Title: FAP-1: a protein tyrosine phosphatase that associates with Fas.

PubMed ID: 7536343

DOI: 10.1126/science.7536343

PubMed ID: 10544233

Title: Functional interaction of Fas-associated phosphatase-1 (FAP-1) with p75(NTR) and their effect on NF-kappaB activation.

PubMed ID: 10544233

DOI: 10.1016/s0014-5793(99)01324-1

PubMed ID: 8483328

Title: Identification of novel protein-tyrosine phosphatases in a human leukemia cell line, F-36P.

PubMed ID: 8483328

PubMed ID: 9305890

Title: A novel GTPase-activating protein for Rho interacts with a PDZ domain of the protein-tyrosine phosphatase PTPL1.

PubMed ID: 9305890

DOI: 10.1074/jbc.272.39.24333

PubMed ID: 10400701

Title: ZRP-1, a zyxin-related protein, interacts with the second PDZ domain of the cytosolic protein tyrosine phosphatase hPTP1E.

PubMed ID: 10400701

DOI: 10.1074/jbc.274.29.20679

PubMed ID: 10826496

Title: The zyxin-related protein TRIP6 interacts with PDZ motifs in the adaptor protein RIL and the protein tyrosine phosphatase PTP-BL.

PubMed ID: 10826496

DOI: 10.1078/s0171-9335(04)70031-x

PubMed ID: 11356191

Title: The protein kinase C-related kinase PRK2 interacts with the protein tyrosine phosphatase PTP-BL via a novel PDZ domain binding motif.

PubMed ID: 11356191

DOI: 10.1016/s0014-5793(01)02401-2

PubMed ID: 14516276

Title: Interaction of the protein tyrosine phosphatase PTPL1 with the PtdIns(3,4)P2-binding adaptor protein TAPP1.

PubMed ID: 14516276

DOI: 10.1042/bj20031154

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19307596

Title: Reversion-induced LIM interaction with Src reveals a novel Src inactivation cycle.

PubMed ID: 19307596

DOI: 10.1083/jcb.200810155

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 23604317

Title: FBXL2- and PTPL1-mediated degradation of p110-free p85beta regulatory subunit controls the PI(3)K signalling cascade.

PubMed ID: 23604317

DOI: 10.1038/ncb2731

PubMed ID: 23108400

Title: The serologically defined colon cancer antigen-3 interacts with the protein tyrosine phosphatase PTPN13 and is involved in the regulation of cytokinesis.

PubMed ID: 23108400

DOI: 10.1038/onc.2012.485

PubMed ID: 29043977

Title: A protein phosphatase network controls the temporal and spatial dynamics of differentiation commitment in human epidermis.

PubMed ID: 29043977

DOI: 10.7554/elife.27356

PubMed ID: 10704206

Title: Solution structure of the PDZ2 domain from human phosphatase hPTP1E and its interactions with C-terminal peptides from the Fas receptor.

PubMed ID: 10704206

DOI: 10.1021/bi991913c

PubMed ID: 12095257

Title: Solution structure of the PDZ2 domain from cytosolic human phosphatase hPTP1E complexed with a peptide reveals contribution of the beta2-beta3 loop to PDZ domain-ligand interactions.

PubMed ID: 12095257

DOI: 10.1016/s0022-2836(02)00544-2

PubMed ID: 15611135

Title: Crystal structure of the PTPL1/FAP-1 human tyrosine phosphatase mutated in colorectal cancer: evidence for a second phosphotyrosine substrate recognition pocket.

PubMed ID: 15611135

DOI: 10.1074/jbc.m412211200

PubMed ID: 12436199

Title: Head-to-head juxtaposition of Fas-associated phosphatase-1 (FAP-1) and c-Jun NH2-terminal kinase 3 (JNK3) genes: genomic structure and seven polymorphisms of the FAP-1 gene.

PubMed ID: 12436199

DOI: 10.1007/s100380200094

Sequence Information:

  • Length: 2485
  • Mass: 276906
  • Checksum: 8D1B31597C66962B
  • Sequence:
    • MHVSLAEALE VRGGPLQEEE IWAVLNQSAE SLQELFRKVS LADPAALGFI ISPWSLLLLP 
SGSVSFTDEN ISNQDLRAFT APEVLQNQSL TSLSDVEKIH IYSLGMTLYW GADYEVPQSQ 
PIKLGDHLNS ILLGMCEDVI YARVSVRTVL DACSAHIRNS NCAPSFSYVK HLVKLVLGNL 
SGTDQLSCNS EQKPDRSQAI RDRLRGKGLP TGRSSTSDVL DIQKPPLSHQ TFLNKGLSKS 
MGFLSIKDTQ DENYFKDILS DNSGREDSEN TFSPYQFKTS GPEKKPIPGI DVLSKKKIWA 
SSMDLLCTAD RDFSSGETAT YRRCHPEAVT VRTSTTPRKK EARYSDGSIA LDIFGPQKMD 
PIYHTRELPT SSAISSALDR IRERQKKLQV LREAMNVEEP VRRYKTYHGD VFSTSSESPS 
IISSESDFRQ VRRSEASKRF ESSSGLPGVD ETLSQGQSQR PSRQYETPFE GNLINQEIML 
KRQEEELMQL QAKMALRQSR LSLYPGDTIK ASMLDITRDP LREIALETAM TQRKLRNFFG 
PEFVKMTIEP FISLDLPRSI LTKKGKNEDN RRKVNIMLLN GQRLELTCDT KTICKDVFDM 
VVAHIGLVEH HLFALATLKD NEYFFVDPDL KLTKVAPEGW KEEPKKKTKA TVNFTLFFRI 
KFFMDDVSLI QHTLTCHQYY LQLRKDILEE RMHCDDETSL LLASLALQAE YGDYQPEVHG 
VSYFRMEHYL PARVMEKLDL SYIKEELPKL HNTYVGASEK ETELEFLKVC QRLTEYGVHF 
HRVHPEKKSQ TGILLGVCSK GVLVFEVHNG VRTLVLRFPW RETKKISFSK KKITLQNTSD 
GIKHGFQTDN SKICQYLLHL CSYQHKFQLQ MRARQSNQDA QDIERASFRS LNLQAESVRG 
FNMGRAISTG SLASSTLNKL AVRPLSVQAE ILKRLSCSEL SLYQPLQNSS KEKNDKASWE 
EKPREMSKSY HDLSQASLYP HRKNVIVNME PPPQTVAELV GKPSHQMSRS DAESLAGVTK 
LNNSKSVASL NRSPERRKHE SDSSSIEDPG QAYVLGMTMH SSGNSSSQVP LKENDVLHKR 
WSIVSSPERE ITLVNLKKDA KYGLGFQIIG GEKMGRLDLG IFISSVAPGG PADLDGCLKP 
GDRLISVNSV SLEGVSHHAA IEILQNAPED VTLVISQPKE KISKVPSTPV HLTNEMKNYM 
KKSSYMQDSA IDSSSKDHHW SRGTLRHISE NSFGPSGGLR EGSLSSQDSR TESASLSQSQ 
VNGFFASHLG DQTWQESQHG SPSPSVISKA TEKETFTDSN QSKTKKPGIS DVTDYSDRGD 
SDMDEATYSS SQDHQTPKQE SSSSVNTSNK MNFKTFSSSP PKPGDIFEVE LAKNDNSLGI 
SVTGGVNTSV RHGGIYVKAV IPQGAAESDG RIHKGDRVLA VNGVSLEGAT HKQAVETLRN 
TGQVVHLLLE KGQSPTSKEH VPVTPQCTLS DQNAQGQGPE KVKKTTQVKD YSFVTEENTF 
EVKLFKNSSG LGFSFSREDN LIPEQINASI VRVKKLFPGQ PAAESGKIDV GDVILKVNGA 
SLKGLSQQEV ISALRGTAPE VFLLLCRPPP GVLPEIDTAL LTPLQSPAQV LPNSSKDSSQ 
PSCVEQSTSS DENEMSDKSK KQCKSPSRRD SYSDSSGSGE DDLVTAPANI SNSTWSSALH 
QTLSNMVSQA QSHHEAPKSQ EDTICTMFYY PQKIPNKPEF EDSNPSPLPP DMAPGQSYQP 
QSESASSSSM DKYHIHHISE PTRQENWTPL KNDLENHLED FELEVELLIT LIKSEKGSLG 
FTVTKGNQRI GCYVHDVIQD PAKSDGRLKP GDRLIKVNDT DVTNMTHTDA VNLLRAASKT 
VRLVIGRVLE LPRIPMLPHL LPDITLTCNK EELGFSLCGG HDSLYQVVYI SDINPRSVAA 
IEGNLQLLDV IHYVNGVSTQ GMTLEEVNRA LDMSLPSLVL KATRNDLPVV PSSKRSAVSA 
PKSTKGNGSY SVGSCSQPAL TPNDSFSTVA GEEINEISYP KGKCSTYQIK GSPNLTLPKE 
SYIQEDDIYD DSQEAEVIQS LLDVVDEEAQ NLLNENNAAG YSCGPGTLKM NGKLSEERTE 
DTDCDGSPLP EYFTEATKMN GCEEYCEEKV KSESLIQKPQ EKKTDDDEIT WGNDELPIER 
TNHEDSDKDH SFLTNDELAV LPVVKVLPSG KYTGANLKSV IRVLRGLLDQ GIPSKELENL 
QELKPLDQCL IGQTKENRRK NRYKNILPYD ATRVPLGDEG GYINASFIKI PVGKEEFVYI 
ACQGPLPTTV GDFWQMIWEQ KSTVIAMMTQ EVEGEKIKCQ RYWPNILGKT TMVSNRLRLA 
LVRMQQLKGF VVRAMTLEDI QTREVRHISH LNFTAWPDHD TPSQPDDLLT FISYMRHIHR 
SGPIITHCSA GIGRSGTLIC IDVVLGLISQ DLDFDISDLV RCMRLQRHGM VQTEDQYIFC 
YQVILYVLTR LQAEEEQKQQ PQLLK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.