Details for: SPTBN2

Gene ID: 6712

Symbol: SPTBN2

Ensembl ID: ENSG00000173898

Description: spectrin beta, non-erythrocytic 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 136.2305
    Cell Significance Index: -21.1900
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 85.8686
    Cell Significance Index: -21.7800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 17.5270
    Cell Significance Index: -21.6100
  • Cell Name: epidermal cell (CL0000362)
    Fold Change: 2.5815
    Cell Significance Index: 5.8200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 1.9243
    Cell Significance Index: 117.9800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.2159
    Cell Significance Index: 243.9100
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.8444
    Cell Significance Index: 12.0200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.7471
    Cell Significance Index: 47.0900
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.5442
    Cell Significance Index: 15.5300
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.5416
    Cell Significance Index: 11.8600
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 0.4620
    Cell Significance Index: 6.6200
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4375
    Cell Significance Index: 43.2800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.4315
    Cell Significance Index: 154.7600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.4068
    Cell Significance Index: 11.3700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.4039
    Cell Significance Index: 27.1600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.3953
    Cell Significance Index: 273.4200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.3432
    Cell Significance Index: 15.1800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3190
    Cell Significance Index: 288.0600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.2971
    Cell Significance Index: 11.2500
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.2160
    Cell Significance Index: 35.1300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.1971
    Cell Significance Index: 21.4400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.1648
    Cell Significance Index: 253.7400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.1495
    Cell Significance Index: 9.1900
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.1448
    Cell Significance Index: 8.6900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1139
    Cell Significance Index: 21.6700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1066
    Cell Significance Index: 4.9700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1066
    Cell Significance Index: 47.1200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0918
    Cell Significance Index: 124.8700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0834
    Cell Significance Index: 2.9300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0818
    Cell Significance Index: 2.0500
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0561
    Cell Significance Index: 1.2000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0539
    Cell Significance Index: 29.4400
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.0478
    Cell Significance Index: 0.5700
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0455
    Cell Significance Index: 0.7800
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0280
    Cell Significance Index: 1.4600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0139
    Cell Significance Index: 25.5500
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: 0.0101
    Cell Significance Index: 0.4400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0046
    Cell Significance Index: 8.7400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0024
    Cell Significance Index: 0.0700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0020
    Cell Significance Index: -0.1200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0050
    Cell Significance Index: -0.9000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0197
    Cell Significance Index: -3.9100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0200
    Cell Significance Index: -14.6400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0208
    Cell Significance Index: -13.2000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0215
    Cell Significance Index: -1.5200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0237
    Cell Significance Index: -4.0400
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0249
    Cell Significance Index: -0.3400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0287
    Cell Significance Index: -21.7300
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0301
    Cell Significance Index: -22.2900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.0308
    Cell Significance Index: -2.1300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0391
    Cell Significance Index: -22.0700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0393
    Cell Significance Index: -17.8500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0397
    Cell Significance Index: -24.8100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0555
    Cell Significance Index: -8.0700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0602
    Cell Significance Index: -7.4000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0628
    Cell Significance Index: -18.0800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0799
    Cell Significance Index: -1.7300
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0853
    Cell Significance Index: -1.7700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0928
    Cell Significance Index: -10.8100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1007
    Cell Significance Index: -13.0200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1108
    Cell Significance Index: -11.3200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1203
    Cell Significance Index: -25.3300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.1242
    Cell Significance Index: -17.0600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1302
    Cell Significance Index: -4.1700
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.1397
    Cell Significance Index: -3.3500
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1724
    Cell Significance Index: -3.6600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1853
    Cell Significance Index: -9.7300
  • Cell Name: sebaceous gland cell (CL2000021)
    Fold Change: -0.1855
    Cell Significance Index: -0.2400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1884
    Cell Significance Index: -21.5900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1888
    Cell Significance Index: -22.2700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1971
    Cell Significance Index: -20.5200
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.2140
    Cell Significance Index: -1.4500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.2206
    Cell Significance Index: -16.9300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.2417
    Cell Significance Index: -11.3600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2569
    Cell Significance Index: -20.3500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2619
    Cell Significance Index: -8.3400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2619
    Cell Significance Index: -19.5200
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.2658
    Cell Significance Index: -3.0200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.2817
    Cell Significance Index: -7.2400
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.2895
    Cell Significance Index: -2.3900
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.2916
    Cell Significance Index: -3.8900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.2934
    Cell Significance Index: -13.3000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2963
    Cell Significance Index: -9.7000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.3449
    Cell Significance Index: -22.2500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.3507
    Cell Significance Index: -18.2700
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.3760
    Cell Significance Index: -5.3900
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.3851
    Cell Significance Index: -13.4900
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.3879
    Cell Significance Index: -7.6700
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.4134
    Cell Significance Index: -8.3000
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.4169
    Cell Significance Index: -10.4000
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: -0.4433
    Cell Significance Index: -4.0400
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.4695
    Cell Significance Index: -4.4500
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.4725
    Cell Significance Index: -7.3100
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.4753
    Cell Significance Index: -7.0200
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.4874
    Cell Significance Index: -10.5300
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.4884
    Cell Significance Index: -17.9300
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.5228
    Cell Significance Index: -6.4900
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.5305
    Cell Significance Index: -5.7800
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.5353
    Cell Significance Index: -14.5700
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.5381
    Cell Significance Index: -11.2300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** SPTBN2 is a cytoskeletal protein that belongs to the spectrin family, which is composed of three main subunits: alpha, beta, and gamma. The SPTBN2 gene encodes the beta subunit, which is crucial for maintaining the structural integrity of the cytoskeleton. The protein consists of four spectrin repeats, each containing three domains: the N-terminal domain, the central domain, and the C-terminal domain. The spectrin repeats are responsible for binding to actin filaments, thereby stabilizing the cytoskeleton. SPTBN2 is also involved in cell-cell adhesion and signaling, particularly in the context of synaptic plasticity. The protein interacts with various signaling molecules, including L1CAM, N-CAM, and NMDA receptors, to regulate synaptic function and plasticity. **Pathways and Functions** SPTBN2 is involved in several cellular pathways, including: 1. **Actin Cytoskeleton Organization**: SPTBN2 plays a crucial role in maintaining the structural integrity of the cytoskeleton by binding to actin filaments and regulating their dynamics. 2. **Cell Junction Formation**: SPTBN2 is involved in the formation and maintenance of cell-cell adhesion complexes, such as adherens junctions and adherens junctions, which are essential for tissue structure and function. 3. **Synaptic Plasticity**: SPTBN2 interacts with signaling molecules to regulate synaptic function and plasticity, including long-term potentiation (LTP) and long-term depression (LTD). 4. **Immune Cell Function**: SPTBN2 is expressed in immune cells, including T cells and dendritic cells, and is involved in the regulation of immune cell function and signaling. 5. **Neuronal Development and Function**: SPTBN2 is expressed in neuronal cells and is involved in the regulation of neuronal development, migration, and function. **Clinical Significance** Dysregulation of SPTBN2 has been implicated in various neurological and immunological disorders, including: 1. **Autism Spectrum Disorder (ASD)**: Studies have shown that SPTBN2 is differentially expressed in individuals with ASD, and that alterations in SPTBN2 function and expression may contribute to the development of ASD. 2. **Schizophrenia**: SPTBN2 has been implicated in the pathophysiology of schizophrenia, with studies suggesting that alterations in SPTBN2 expression and function may contribute to the development of the disorder. 3. **Multiple Sclerosis**: SPTBN2 has been shown to be differentially expressed in multiple sclerosis, and alterations in SPTBN2 function and expression may contribute to the development of the disease. 4. **Immune-Mediated Disorders**: SPTBN2 has been implicated in the pathophysiology of immune-mediated disorders, including rheumatoid arthritis and lupus, with alterations in SPTBN2 expression and function contributing to disease progression. In conclusion, SPTBN2 is a crucial protein involved in various cellular processes, including actin cytoskeleton organization, cell junction formation, and synaptic plasticity. Dysregulation of SPTBN2 has been implicated in various neurological and immunological disorders, highlighting the importance of further research into the role of this gene in human disease.

Genular Protein ID: 1114397215

Symbol: SPTN2_HUMAN

Name: Spectrin beta chain, non-erythrocytic 2

UniProtKB Accession Codes:

O15020 O14872 O14873

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 4 CTD 1 CarbonylDB 1 ChiTaRS 1 DIP 1 DNASU 1 DisGeNET 1 EMBL 6 EMDB 1 Ensembl 5 EvolutionaryTrace 1 ExpressionAtlas 1 GO 30 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 10 KEGG 1 MANE-Select 1 MIM 5 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PDB 3 PDBsum 3 PIRSF 1 PRINTS 1 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 5 RefSeq 9 SMART 3 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9205841

Title: Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PubMed ID: 9205841

DOI: 10.1093/dnares/4.2.141

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 9826670

Title: A widely expressed betaIII spectrin associated with Golgi and cytoplasmic vesicles.

PubMed ID: 9826670

DOI: 10.1073/pnas.95.24.14158

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23236289

Title: Recessive mutations in SPTBN2 implicate beta-III spectrin in both cognitive and motor development.

PubMed ID: 23236289

DOI: 10.1371/journal.pgen.1003074

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 23838597

Title: Autosomal dominant SCA5 and autosomal recessive infantile SCA are allelic conditions resulting from SPTBN2 mutations.

PubMed ID: 23838597

DOI: 10.1038/ejhg.2013.150

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 16429157

Title: Spectrin mutations cause spinocerebellar ataxia type 5.

PubMed ID: 16429157

DOI: 10.1038/ng1728

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

PubMed ID: 22914369

Title: Case of infantile onset spinocerebellar ataxia type 5.

PubMed ID: 22914369

DOI: 10.1177/0883073812454331

Sequence Information:

  • Length: 2390
  • Mass: 271325
  • Checksum: 1CC523CC6493DBFE
  • Sequence:
    • MSSTLSPTDF DSLEIQGQYS DINNRWDLPD SDWDNDSSSA RLFERSRIKA LADEREAVQK 
KTFTKWVNSH LARVTCRVGD LYSDLRDGRN LLRLLEVLSG EILPKPTKGR MRIHCLENVD 
KALQFLKEQK VHLENMGSHD IVDGNHRLTL GLVWTIILRF QIQDISVETE DNKEKKSAKD 
ALLLWCQMKT AGYPNVNVHN FTTSWRDGLA FNAIVHKHRP DLLDFESLKK CNAHYNLQNA 
FNLAEKELGL TKLLDPEDVN VDQPDEKSII TYVATYYHYF SKMKALAVEG KRIGKVLDHA 
MEAERLVEKY ESLASELLQW IEQTIVTLND RQLANSLSGV QNQLQSFNSY RTVEKPPKFT 
EKGNLEVLLF TIQSKLRANN QKVYTPREGR LISDINKAWE RLEKAEHERE LALRTELIRQ 
EKLEQLAARF DRKAAMRETW LSENQRLVSQ DNFGLELAAV EAAVRKHEAI ETDIVAYSGR 
VQAVDAVAAE LAAERYHDIK RIAARQHNVA RLWDFLRQMV AARRERLLLN LELQKVFQDL 
LYLMDWMEEM KGRLQSQDLG RHLAGVEDLL QLHELVEADI AVQAERVRAV SASALRFCNP 
GKEYRPCDPQ LVSERVAKLE QSYEALCELA AARRARLEES RRLWRFLWEV GEAEAWVREQ 
QHLLASADTG RDLTGALRLL NKHTALRGEM SGRLGPLKLT LEQGQQLVAE GHPGASQASA 
RAAELQAQWE RLEALAEERA QRLAQAASLY QFQADANDME AWLVDALRLV SSPELGHDEF 
STQALARQHR ALEEEIRSHR PTLDALREQA AALPPTLSRT PEVQSRVPTL ERHYEELQAR 
AGERARALEA ALALYTMLSE AGACGLWVEE KEQWLNGLAL PERLEDLEVV QQRFETLEPE 
MNTLAAQITA VNDIAEQLLK ANPPGKDRIV NTQEQLNHRW QQFRRLADGK KAALTSALSI 
QNYHLECTET QAWMREKTKV IESTQGLGND LAGVLALQRK LAGTERDLEA IAARVGELTR 
EANALAAGHP AQAVAINARL REVQTGWEDL RATMRRREES LGEARRLQDF LRSLDDFQAW 
LGRTQTAVAS EEGPATLPEA EALLAQHAAL RGEVERAQSE YSRLRALGEE VTRDQADPQC 
LFLRQRLEAL GTGWEELGRM WESRQGRLAQ AHGFQGFLRD ARQAEGVLSS QEYVLSHTEM 
PGTLQAADAA IKKLEDFMST MDANGERIHG LLEAGRQLVS EGNIHADKIR EKADSIERRH 
KKNQDAAQQF LGRLRDNREQ QHFLQDCHEL KLWIDEKMLT AQDVSYDEAR NLHTKWQKHQ 
AFMAELAANK DWLDKVDKEG RELTLEKPEL KALVSEKLRD LHRRWDELET TTQAKARSLF 
DANRAELFAQ SCCALESWLE SLQAQLHSDD YGKDLTSVNI LLKKQQMLEW EMAVREKEVE 
AIQAQAKALA QEDQGAGEVE RTSRAVEEKF RALCQPMRER CRRLQASREQ HQFHRDVEDE 
ILWVTERLPM ASSMEHGKDL PSVQLLMKKN QTLQKEIQGH EPRIADLRER QRALGAAAAG 
PELAELQEMW KRLGHELELR GKRLEDALRA QQFYRDAAEA EAWMGEQELH MMGQEKAKDE 
LSAQAEVKKH QVLEQALADY AQTIHQLAAS SQDMIDHEHP ESTRISIRQA QVDKLYAGLK 
ELAGERRERL QEHLRLCQLR RELDDLEQWI QEREVVAASH ELGQDYEHVT MLRDKFREFS 
RDTSTIGQER VDSANALANG LIAGGHAARA TVAEWKDSLN EAWADLLELL DTRGQVLAAA 
YELQRFLHGA RQALARVQHK QQQLPDGTGR DLNAAEALQR RHCAYEHDIQ ALSPQVQQVQ 
DDGHRLQKAY AGDKAEEIGR HMQAVAEAWA QLQGSSAARR QLLLDTTDKF RFFKAVRELM 
LWMDEVNLQM DAQERPRDVS SADLVIKNQQ GIKAEIEARA DRFSSCIDMG KELLARSHYA 
AEEISEKLSQ LQARRQETAE KWQEKMDWLQ LVLEVLVFGR DAGMAEAWLC SQEPLVRSAE 
LGCTVDEVES LIKRHEAFQK SAVAWEERFC ALEKLTALEE REKERKRKRE EEERRKQPPA 
PEPTASVPPG DLVGGQTASD TTWDGTQPRP PPSTQAPSVN GVCTDGEPSQ PLLGQQRLEH 
SSFPEGPGPG SGDEANGPRG ERQTRTRGPA PSAMPQSRST ESAHAATLPP RGPEPSAQEQ 
MEGMLCRKQE MEAFGKKAAN RSWQNVYCVL RRGSLGFYKD AKAASAGVPY HGEVPVSLAR 
AQGSVAFDYR KRKHVFKLGL QDGKEYLFQA KDEAEMSSWL RVVNAAIATA SSASGEPEEP 
VVPSTTRGMT RAMTMPPVSP VGAEGPVVLR SKDGRERERE KRFSFFKKNK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.