Details for: TLR1

Gene ID: 7096

Symbol: TLR1

Ensembl ID: ENSG00000174125

Description: toll like receptor 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 60.1754
    Cell Significance Index: -9.3600
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 35.0886
    Cell Significance Index: -8.9000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 20.7996
    Cell Significance Index: -8.4500
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 19.2463
    Cell Significance Index: -9.9000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 8.8610
    Cell Significance Index: -8.4600
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 7.6321
    Cell Significance Index: -9.4100
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 1.3342
    Cell Significance Index: -2.9200
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 1.1379
    Cell Significance Index: 17.6100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.0709
    Cell Significance Index: 203.8000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.7158
    Cell Significance Index: 15.2500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.6832
    Cell Significance Index: 67.5800
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.5822
    Cell Significance Index: 10.7600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5487
    Cell Significance Index: 495.4100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.4091
    Cell Significance Index: 44.5000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3690
    Cell Significance Index: 60.0100
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.3684
    Cell Significance Index: 22.1200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.2601
    Cell Significance Index: 6.9700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2097
    Cell Significance Index: 14.5100
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 0.1987
    Cell Significance Index: 1.6200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.1629
    Cell Significance Index: 19.2100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0687
    Cell Significance Index: 4.4300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0679
    Cell Significance Index: 3.1900
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.0523
    Cell Significance Index: 1.4000
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 0.0458
    Cell Significance Index: 0.6900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0266
    Cell Significance Index: 0.7700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0234
    Cell Significance Index: 1.0900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0208
    Cell Significance Index: 0.4500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0126
    Cell Significance Index: 1.6200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0104
    Cell Significance Index: 0.2600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0104
    Cell Significance Index: 4.5800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0028
    Cell Significance Index: -0.1000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0029
    Cell Significance Index: -0.5800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0031
    Cell Significance Index: -5.8600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0057
    Cell Significance Index: -0.2600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0060
    Cell Significance Index: -11.0600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0073
    Cell Significance Index: -11.2800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0091
    Cell Significance Index: -12.3600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0094
    Cell Significance Index: -2.7000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0097
    Cell Significance Index: -7.1300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0104
    Cell Significance Index: -5.6800
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: -0.0114
    Cell Significance Index: -0.1600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0115
    Cell Significance Index: -7.3100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0122
    Cell Significance Index: -9.2200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0155
    Cell Significance Index: -11.5000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0156
    Cell Significance Index: -2.8200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0160
    Cell Significance Index: -5.7400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0164
    Cell Significance Index: -10.2400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0188
    Cell Significance Index: -8.5500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0204
    Cell Significance Index: -11.5100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0223
    Cell Significance Index: -2.2800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0284
    Cell Significance Index: -4.8500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0289
    Cell Significance Index: -5.8000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0377
    Cell Significance Index: -4.6400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0386
    Cell Significance Index: -5.6100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0399
    Cell Significance Index: -5.4800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0414
    Cell Significance Index: -5.3500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0533
    Cell Significance Index: -11.2200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0539
    Cell Significance Index: -6.2900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0570
    Cell Significance Index: -6.5300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0680
    Cell Significance Index: -1.9000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0705
    Cell Significance Index: -4.3200
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0792
    Cell Significance Index: -4.0000
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: -0.0833
    Cell Significance Index: -1.0000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0902
    Cell Significance Index: -9.3900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1027
    Cell Significance Index: -7.2600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1071
    Cell Significance Index: -7.9800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1095
    Cell Significance Index: -8.4000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1105
    Cell Significance Index: -3.5400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1173
    Cell Significance Index: -9.2900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.1233
    Cell Significance Index: -6.4100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1275
    Cell Significance Index: -8.5700
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.1465
    Cell Significance Index: -6.3700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1492
    Cell Significance Index: -7.7700
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.1539
    Cell Significance Index: -4.5200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.1576
    Cell Significance Index: -2.1500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1603
    Cell Significance Index: -9.8500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1799
    Cell Significance Index: -10.1000
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.1906
    Cell Significance Index: -4.8700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1962
    Cell Significance Index: -10.3000
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: -0.2018
    Cell Significance Index: -1.6400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2200
    Cell Significance Index: -9.7300
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.2276
    Cell Significance Index: -5.8500
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.2306
    Cell Significance Index: -4.5000
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: -0.2385
    Cell Significance Index: -2.6100
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.2393
    Cell Significance Index: -3.4000
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.2401
    Cell Significance Index: -3.1900
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.2437
    Cell Significance Index: -3.4900
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.2569
    Cell Significance Index: -3.0200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2600
    Cell Significance Index: -9.8500
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2673
    Cell Significance Index: -8.7500
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2698
    Cell Significance Index: -9.4500
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.2700
    Cell Significance Index: -9.9100
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: -0.2824
    Cell Significance Index: -4.1300
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2864
    Cell Significance Index: -9.1200
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.2870
    Cell Significance Index: -7.1600
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: -0.2879
    Cell Significance Index: -4.1800
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.2925
    Cell Significance Index: -7.8100
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.3092
    Cell Significance Index: -4.4400
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: -0.3112
    Cell Significance Index: -3.8500
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.3138
    Cell Significance Index: -6.1400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** TLR1 exhibits several key characteristics that enable its function as a pattern recognition receptor (PRR). These include: 1. **Ligand recognition**: TLR1 is capable of recognizing a variety of ligands, including bacterial lipopeptides, triacyl lipopeptides, and other PAMPs. 2. **Receptor complex formation**: TLR1 forms a receptor complex with other TLRs, such as TLR2, to enhance its ligand recognition and signaling capabilities. 3. **Signaling pathway activation**: Upon ligand binding, TLR1 activates downstream signaling pathways, leading to the production of pro-inflammatory cytokines, chemokines, and type I interferons. 4. **Cellular localization**: TLR1 is expressed on various cell types, including myeloid leukocytes, macrophages, and dendritic cells, allowing it to survey the body for pathogens and initiate an immune response. 5. **Expression regulation**: TLR1 expression is tightly regulated by various factors, including transcriptional and post-transcriptional mechanisms, to ensure proper immune function. **Pathways and Functions** The TLR1 signaling pathway involves the activation of several key molecules, including: 1. **MyD88**: A critical adapter protein that mediates the signaling from TLR1 to downstream effectors. 2. **IRAK4**: A protein that interacts with MyD88 to enhance the signaling from TLR1. 3. **TRAF6**: A protein that interacts with MyD88 to activate the NF-κB transcription factor, leading to the production of pro-inflammatory cytokines and chemokines. 4. **NF-κB**: A transcription factor that regulates the expression of genes involved in inflammation and immune response. The TLR1 signaling pathway plays a critical role in the regulation of various immune responses, including: 1. **Innate immune response**: TLR1 helps to recognize and eliminate pathogens, such as bacteria and viruses. 2. **Adaptive immune response**: TLR1 can also activate the adaptive immune response by stimulating the production of cytokines and chemokines that recruit immune cells to the site of infection. 3. **Autoimmunity**: Dysregulation of TLR1 signaling has been implicated in various autoimmune diseases, such as rheumatoid arthritis and lupus. **Clinical Significance** Dysregulation of TLR1 signaling has been implicated in various diseases, including: 1. **Infectious diseases**: TLR1 plays a critical role in the recognition and elimination of pathogens, such as bacteria and viruses. 2. **Autoimmune diseases**: Dysregulation of TLR1 signaling has been implicated in various autoimmune diseases, including rheumatoid arthritis and lupus. 3. **Cancer**: TLR1 has been shown to play a role in the regulation of tumor progression and immune evasion. 4. **Neurological diseases**: TLR1 has been implicated in the pathogenesis of various neurological diseases, including Alzheimer's disease and multiple sclerosis. In conclusion, TLR1 is a critical component of the innate immune system, playing a pivotal role in the recognition and response to microbial pathogens. Its dysregulation has been implicated in various diseases, highlighting the importance of TLR1 in maintaining immune homeostasis and preventing disease.

Genular Protein ID: 819199836

Symbol: TLR1_HUMAN

Name: Toll-like receptor 1

UniProtKB Accession Codes:

Q15399 D1CS39 D1CS41 O15452 Q32MK3 Q32MK4 Q9UG90

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CORUM 1 CTD 1 ChEMBL 1 ComplexPortal 2 DMDM 1 DNASU 1 DisGeNET 1 EMBL 9 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 25 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 2 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 6 PDBsum 6 PIR 1 PIRSF 1 PRINTS 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 8 RefSeq 8 SMART 4 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9435236

Title: A family of human receptors structurally related to Drosophila Toll.

PubMed ID: 9435236

DOI: 10.1073/pnas.95.2.588

PubMed ID: 18810425

Title: Natural selection in the TLR-related genes in the course of primate evolution.

PubMed ID: 18810425

DOI: 10.1007/s00251-008-0332-0

PubMed ID: 19924287

Title: The heterogeneous allelic repertoire of human Toll-Like receptor (TLR) genes.

PubMed ID: 19924287

DOI: 10.1371/journal.pone.0007803

PubMed ID: 7584026

Title: Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1.

PubMed ID: 7584026

DOI: 10.1093/dnares/1.1.27

PubMed ID: 11230166

Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

PubMed ID: 11230166

DOI: 10.1101/gr.gr1547r

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15340161

Title: Signal peptide prediction based on analysis of experimentally verified cleavage sites.

PubMed ID: 15340161

DOI: 10.1110/ps.04682504

PubMed ID: 16880211

Title: Membrane sorting of toll-like receptor (TLR)-2/6 and TLR2/1 heterodimers at the cell surface determines heterotypic associations with CD36 and intracellular targeting.

PubMed ID: 16880211

DOI: 10.1074/jbc.m602794200

PubMed ID: 17548585

Title: Cutting edge: A common polymorphism impairs cell surface trafficking and functional responses of TLR1 but protects against leprosy.

PubMed ID: 17548585

DOI: 10.4049/jimmunol.178.12.7520

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 21078852

Title: Mycobacterium tuberculosis lipoproteins directly regulate human memory CD4(+) T cell activation via Toll-like receptors 1 and 2.

PubMed ID: 21078852

DOI: 10.1128/iai.00806-10

PubMed ID: 38378891

Title: A mosquito salivary protein-driven influx of myeloid cells facilitates flavivirus transmission.

PubMed ID: 38378891

DOI: 10.1038/s44318-024-00056-x

PubMed ID: 11081518

Title: Structural basis for signal transduction by the Toll/interleukin-1 receptor domains.

PubMed ID: 11081518

DOI: 10.1038/35040600

PubMed ID: 17889651

Title: Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide.

PubMed ID: 17889651

DOI: 10.1016/j.cell.2007.09.008

PubMed ID: 19456232

Title: Polymorphism N248S in the human Toll-like receptor 1 gene is related to leprosy and leprosy reactions.

PubMed ID: 19456232

DOI: 10.1086/599121

PubMed ID: 21618349

Title: Functional characterization of naturally occurring genetic variants in the human TLR1-2-6 gene family.

PubMed ID: 21618349

DOI: 10.1002/humu.21486

Sequence Information:

  • Length: 786
  • Mass: 90291
  • Checksum: 1BFCCC5E42EA5242
  • Sequence:
    • MTSIFHFAII FMLILQIRIQ LSEESEFLVD RSKNGLIHVP KDLSQKTTIL NISQNYISEL 
WTSDILSLSK LRILIISHNR IQYLDISVFK FNQELEYLDL SHNKLVKISC HPTVNLKHLD 
LSFNAFDALP ICKEFGNMSQ LKFLGLSTTH LEKSSVLPIA HLNISKVLLV LGETYGEKED 
PEGLQDFNTE SLHIVFPTNK EFHFILDVSV KTVANLELSN IKCVLEDNKC SYFLSILAKL 
QTNPKLSNLT LNNIETTWNS FIRILQLVWH TTVWYFSISN VKLQGQLDFR DFDYSGTSLK 
ALSIHQVVSD VFGFPQSYIY EIFSNMNIKN FTVSGTRMVH MLCPSKISPF LHLDFSNNLL 
TDTVFENCGH LTELETLILQ MNQLKELSKI AEMTTQMKSL QQLDISQNSV SYDEKKGDCS 
WTKSLLSLNM SSNILTDTIF RCLPPRIKVL DLHSNKIKSI PKQVVKLEAL QELNVAFNSL 
TDLPGCGSFS SLSVLIIDHN SVSHPSADFF QSCQKMRSIK AGDNPFQCTC ELGEFVKNID 
QVSSEVLEGW PDSYKCDYPE SYRGTLLKDF HMSELSCNIT LLIVTIVATM LVLAVTVTSL 
CSYLDLPWYL RMVCQWTQTR RRARNIPLEE LQRNLQFHAF ISYSGHDSFW VKNELLPNLE 
KEGMQICLHE RNFVPGKSIV ENIITCIEKS YKSIFVLSPN FVQSEWCHYE LYFAHHNLFH 
EGSNSLILIL LEPIPQYSIP SSYHKLKSLM ARRTYLEWPK EKSKRGLFWA NLRAAINIKL 
TEQAKK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.