Details for: TNFSF4

Gene ID: 7292

Symbol: TNFSF4

Ensembl ID: ENSG00000117586

Description: TNF superfamily member 4

Associated with

  • Cytokine signaling in immune system
    (R-HSA-1280215)
  • Immune system
    (R-HSA-168256)
  • Tnfr2 non-canonical nf-kb pathway
    (R-HSA-5668541)
  • Tnfs bind their physiological receptors
    (R-HSA-5669034)
  • Acute inflammatory response
    (GO:0002526)
  • Cell surface
    (GO:0009986)
  • Cellular response to lipopolysaccharide
    (GO:0071222)
  • Cellular response to prostaglandin e stimulus
    (GO:0071380)
  • Cytokine activity
    (GO:0005125)
  • Defense response to nematode
    (GO:0002215)
  • Extracellular space
    (GO:0005615)
  • Immune response
    (GO:0006955)
  • Inflammatory response
    (GO:0006954)
  • Memory t cell activation
    (GO:0035709)
  • Negative regulation of dna-binding transcription factor activity
    (GO:0043433)
  • Negative regulation of dna-templated transcription
    (GO:0045892)
  • Negative regulation of interleukin-17 production
    (GO:0032700)
  • Negative regulation of regulatory t cell differentiation
    (GO:0045590)
  • Negative regulation of t-helper 1 cell differentiation
    (GO:0045626)
  • Negative regulation of type ii interferon production
    (GO:0032689)
  • Plasma membrane
    (GO:0005886)
  • Positive regulation of alpha-beta t cell proliferation
    (GO:0046641)
  • Positive regulation of b cell activation
    (GO:0050871)
  • Positive regulation of cd4-positive, alpha-beta t cell costimulation
    (GO:1900281)
  • Positive regulation of cd4-positive, alpha-beta t cell differentiation
    (GO:0043372)
  • Positive regulation of cell population proliferation
    (GO:0008284)
  • Positive regulation of chemokine production
    (GO:0032722)
  • Positive regulation of cytokine production
    (GO:0001819)
  • Positive regulation of immunoglobulin mediated immune response
    (GO:0002891)
  • Positive regulation of immunoglobulin production
    (GO:0002639)
  • Positive regulation of inflammatory response
    (GO:0050729)
  • Positive regulation of interleukin-4 production
    (GO:0032753)
  • Positive regulation of interleukin-4-dependent isotype switching to ige isotypes
    (GO:2000572)
  • Positive regulation of interleukin-6 production
    (GO:0032755)
  • Positive regulation of interleukin-10 production
    (GO:0032733)
  • Positive regulation of interleukin-12 production
    (GO:0032735)
  • Positive regulation of interleukin-13 production
    (GO:0032736)
  • Positive regulation of memory t cell differentiation
    (GO:0043382)
  • Positive regulation of t-helper 2 cell differentiation
    (GO:0045630)
  • Positive regulation of t cell cytokine production
    (GO:0002726)
  • Positive regulation of t cell proliferation
    (GO:0042102)
  • Positive regulation of type 2 immune response
    (GO:0002830)
  • Positive regulation of type ii interferon production
    (GO:0032729)
  • Protein binding
    (GO:0005515)
  • Regulation of adaptive immune response
    (GO:0002819)
  • Regulation of inflammatory response
    (GO:0050727)
  • Response to nitrogen dioxide
    (GO:0035713)
  • Response to virus
    (GO:0009615)
  • Signaling receptor binding
    (GO:0005102)
  • Signal transduction
    (GO:0007165)
  • T-helper 2 cell activation
    (GO:0035712)
  • Tumor necrosis factor receptor binding
    (GO:0005164)
  • Tumor necrosis factor receptor superfamily binding
    (GO:0032813)

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 25.4267
    Cell Significance Index: -3.9600
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 9.1078
    Cell Significance Index: -4.3000
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 9.0982
    Cell Significance Index: -4.6800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 3.2077
    Cell Significance Index: -3.9600
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 2.2218
    Cell Significance Index: 46.0900
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 1.7760
    Cell Significance Index: 62.4100
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 1.4633
    Cell Significance Index: 22.6400
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 1.3602
    Cell Significance Index: -0.3500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.2306
    Cell Significance Index: 35.4600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 1.1179
    Cell Significance Index: 35.8100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 1.1047
    Cell Significance Index: 27.6200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.8292
    Cell Significance Index: 17.9700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 0.7757
    Cell Significance Index: 47.5600
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 0.5488
    Cell Significance Index: 9.2300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2649
    Cell Significance Index: 50.4200
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: 0.2521
    Cell Significance Index: 3.6100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.1813
    Cell Significance Index: 36.3600
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: 0.1528
    Cell Significance Index: 2.1500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.1283
    Cell Significance Index: 8.2800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.1103
    Cell Significance Index: 21.8900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.1097
    Cell Significance Index: 2.9400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1086
    Cell Significance Index: 10.7400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.1069
    Cell Significance Index: 96.5100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1021
    Cell Significance Index: 36.6200
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.0986
    Cell Significance Index: 5.9200
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.0845
    Cell Significance Index: 9.1900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0805
    Cell Significance Index: 1.7200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0699
    Cell Significance Index: 3.1700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.0692
    Cell Significance Index: 4.6500
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.0672
    Cell Significance Index: 10.9400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.0442
    Cell Significance Index: 6.4200
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.0429
    Cell Significance Index: 0.6800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.0372
    Cell Significance Index: 2.5800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.0244
    Cell Significance Index: 1.0800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0195
    Cell Significance Index: 13.5000
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.0156
    Cell Significance Index: 0.5900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0154
    Cell Significance Index: 1.1800
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.0146
    Cell Significance Index: 0.7400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0077
    Cell Significance Index: 14.5100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0023
    Cell Significance Index: 4.2900
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 0.0019
    Cell Significance Index: 0.0400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0017
    Cell Significance Index: 2.6600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0013
    Cell Significance Index: 0.8100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.0003
    Cell Significance Index: 0.0300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0006
    Cell Significance Index: -0.7900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0009
    Cell Significance Index: -0.1100
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0016
    Cell Significance Index: -0.0400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0031
    Cell Significance Index: -2.2400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0037
    Cell Significance Index: -2.0000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0038
    Cell Significance Index: -1.7100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0054
    Cell Significance Index: -2.4000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0057
    Cell Significance Index: -4.2800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0059
    Cell Significance Index: -4.3700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0066
    Cell Significance Index: -3.7500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0068
    Cell Significance Index: -1.9600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0136
    Cell Significance Index: -2.4500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0146
    Cell Significance Index: -2.0000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0214
    Cell Significance Index: -3.6500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0221
    Cell Significance Index: -4.6600
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0225
    Cell Significance Index: -0.4400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0252
    Cell Significance Index: -3.1000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0277
    Cell Significance Index: -3.2700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0315
    Cell Significance Index: -3.2200
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0324
    Cell Significance Index: -0.7100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0326
    Cell Significance Index: -3.3900
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.0336
    Cell Significance Index: -0.9000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0361
    Cell Significance Index: -4.6600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0386
    Cell Significance Index: -4.4200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0390
    Cell Significance Index: -2.4600
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0420
    Cell Significance Index: -0.8300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0425
    Cell Significance Index: -2.6100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0481
    Cell Significance Index: -2.5000
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0487
    Cell Significance Index: -1.5500
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0513
    Cell Significance Index: -1.3500
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0525
    Cell Significance Index: -1.7200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0532
    Cell Significance Index: -4.2100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0534
    Cell Significance Index: -2.4900
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: -0.0577
    Cell Significance Index: -0.8100
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0585
    Cell Significance Index: -3.2800
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0607
    Cell Significance Index: -1.0400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0609
    Cell Significance Index: -3.2000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0612
    Cell Significance Index: -1.7100
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0617
    Cell Significance Index: -2.1600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0623
    Cell Significance Index: -4.6400
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.0723
    Cell Significance Index: -1.2500
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0764
    Cell Significance Index: -1.6500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0764
    Cell Significance Index: -3.5900
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.0767
    Cell Significance Index: -2.1900
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0771
    Cell Significance Index: -2.2100
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.0786
    Cell Significance Index: -1.1900
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0842
    Cell Significance Index: -1.6900
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0870
    Cell Significance Index: -2.1700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0883
    Cell Significance Index: -2.2700
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.1016
    Cell Significance Index: -1.2600
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.1049
    Cell Significance Index: -3.8500
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.1065
    Cell Significance Index: -4.3600
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.1107
    Cell Significance Index: -0.7500
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: -0.1113
    Cell Significance Index: -1.4100
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.1121
    Cell Significance Index: -2.3400
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.1126
    Cell Significance Index: -2.7000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** TNFSF4 is a type II member of the TNF superfamily, which consists of six ligands (TNFSF1, TNFSF2, TNFSF3, TNFSF4, TNFSF5, and TNFSF6) and four receptors (TNFR1, TNFR2, TNFR3, and TNFRSF1A). TNFSF4 is a transmembrane protein that binds to its receptor, TNFR2, to activate signaling pathways. The binding of TNFSF4 to TNFR2 triggers the activation of NF-κB and MAPK pathways, leading to the transcription of target genes involved in immune responses, inflammation, and cell proliferation. **Pathways and Functions** TNFSF4 is involved in various signaling pathways, including: 1. **Acute Inflammatory Response**: TNFSF4 is expressed in epithelial cells and plays a role in regulating the acute inflammatory response by inducing the production of pro-inflammatory cytokines, such as TNF-α and IL-1β. 2. **Cellular Response to Lipopolysaccharide**: TNFSF4 is involved in the regulation of the cellular response to lipopolysaccharide (LPS), a potent stimulator of immune responses. 3. **Cytokine Signaling in Immune System**: TNFSF4 regulates cytokine signaling in the immune system, including the production of IL-4, IL-6, and IL-10, which are involved in the regulation of immune responses and inflammation. 4. **Negative Regulation of DNA-Binding Transcription Factor Activity**: TNFSF4 also regulates the activity of DNA-binding transcription factors, such as NF-κB, which are involved in the regulation of gene expression. **Clinical Significance** TNFSF4 has been implicated in various diseases, including: 1. **Autoimmune Diseases**: TNFSF4 has been shown to regulate the activity of immune cells, including T cells and B cells, which are involved in autoimmune diseases, such as rheumatoid arthritis and lupus. 2. **Cancer**: TNFSF4 has been implicated in the regulation of cancer cell growth and survival, and its expression has been linked to various types of cancer, including lung, breast, and colon cancer. 3. **Inflammatory Diseases**: TNFSF4 has been shown to regulate the production of pro-inflammatory cytokines, which are involved in inflammatory diseases, such as asthma and inflammatory bowel disease. In conclusion, TNFSF4 is a critical regulator of immune responses, inflammation, and cell proliferation. Its dysregulation has been implicated in various diseases, highlighting the importance of this gene in maintaining immune homeostasis and preventing disease.

Genular Protein ID: 3697911300

Symbol: TNFL4_HUMAN

Name: Tumor necrosis factor ligand superfamily member 4

UniProtKB Accession Codes:

P23510 Q5JZA5 Q8IV74 Q9HCN9

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 7 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 48 Gene3D 1 GeneCards 1 GeneTree 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 1 RefSeq 2 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1996093

Title: Molecular cloning and characterization of a novel glycoprotein, gp34, that is specifically induced by the human T-cell leukemia virus type I transactivator p40tax.

PubMed ID: 1996093

DOI: 10.1128/mcb.11.3.1313-1325.1991

PubMed ID: 7913952

Title: Identification of a human OX-40 ligand, a costimulator of CD4+ T cells with homology to tumor necrosis factor.

PubMed ID: 7913952

DOI: 10.1084/jem.180.2.757

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11197696

Title: New variations in human OX40 ligand (CD134L) gene.

PubMed ID: 11197696

DOI: 10.1038/sj.gene.6363709

PubMed ID: 8076595

Title: Molecular characterization of murine and human OX40/OX40 ligand systems: identification of a human OX40 ligand as the HTLV-1-regulated protein gp34.

PubMed ID: 8076595

DOI: 10.1002/j.1460-2075.1994.tb06715.x

PubMed ID: 18059267

Title: Polymorphism at the TNF superfamily gene TNFSF4 confers susceptibility to systemic lupus erythematosus.

PubMed ID: 18059267

DOI: 10.1038/ng.2007.47

PubMed ID: 16905106

Title: The crystal structure of the costimulatory OX40-OX40L complex.

PubMed ID: 16905106

DOI: 10.1016/j.str.2006.06.015

Sequence Information:

  • Length: 183
  • Mass: 21050
  • Checksum: 0D5604AD29D529CF
  • Sequence:
    • MERVQPLEEN VGNAARPRFE RNKLLLVASV IQGLGLLLCF TYICLHFSAL QVSHRYPRIQ 
SIKVQFTEYK KEKGFILTSQ KEDEIMKVQN NSVIINCDGF YLISLKGYFS QEVNISLHYQ 
KDEEPLFQLK KVRSVNSLMV ASLTYKDKVY LNVTTDNTSL DDFHVNGGEL ILIHQNPGEF 
CVL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.