Details for: ZNF74
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 55.0322
Cell Significance Index: -8.5600 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 30.7124
Cell Significance Index: -7.7900 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 7.0887
Cell Significance Index: -8.7400 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 3.2066
Cell Significance Index: -8.5900 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.8494
Cell Significance Index: 22.7600 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.7789
Cell Significance Index: 77.0600 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 0.6351
Cell Significance Index: -1.3900 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.5320
Cell Significance Index: 480.3500 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.5060
Cell Significance Index: 11.0800 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.4491
Cell Significance Index: 48.8500 - Cell Name: proerythroblast (CL0000547)
Fold Change: 0.3993
Cell Significance Index: 5.7200 - Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
Fold Change: 0.3926
Cell Significance Index: 5.5100 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.3867
Cell Significance Index: 77.5700 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.3851
Cell Significance Index: 62.6300 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.2214
Cell Significance Index: 153.1100 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.2180
Cell Significance Index: 13.4000 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.2155
Cell Significance Index: 14.9000 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.2040
Cell Significance Index: 73.1700 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.1923
Cell Significance Index: 5.5400 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.1576
Cell Significance Index: 3.7800 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.1560
Cell Significance Index: 18.1900 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 0.1414
Cell Significance Index: 4.9200 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.1410
Cell Significance Index: 27.9800 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1376
Cell Significance Index: 26.1800 - Cell Name: decidual cell (CL2000002)
Fold Change: 0.1234
Cell Significance Index: 1.9800 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.1057
Cell Significance Index: 4.7900 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.1032
Cell Significance Index: 5.3600 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.0869
Cell Significance Index: 1.8200 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.0811
Cell Significance Index: 4.5500 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0729
Cell Significance Index: 39.7900 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.0610
Cell Significance Index: 8.3800 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.0512
Cell Significance Index: 1.1100 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.0497
Cell Significance Index: 1.3900 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0476
Cell Significance Index: 21.0600 - Cell Name: pro-T cell (CL0000827)
Fold Change: 0.0384
Cell Significance Index: 0.9800 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0359
Cell Significance Index: 1.2600 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0333
Cell Significance Index: 6.0000 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0203
Cell Significance Index: 2.6000 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.0139
Cell Significance Index: 0.6500 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.0114
Cell Significance Index: 0.7200 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.0070
Cell Significance Index: 0.1500 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0046
Cell Significance Index: 8.5900 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.0040
Cell Significance Index: 0.2600 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.0015
Cell Significance Index: 0.1900 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: -0.0009
Cell Significance Index: -0.0100 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0043
Cell Significance Index: -7.8700 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0045
Cell Significance Index: -6.8600 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0055
Cell Significance Index: -3.5000 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0064
Cell Significance Index: -8.7300 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0084
Cell Significance Index: -6.1900 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.0088
Cell Significance Index: -0.1500 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0091
Cell Significance Index: -6.8700 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0116
Cell Significance Index: -0.6100 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0117
Cell Significance Index: -8.6400 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0134
Cell Significance Index: -6.0900 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0149
Cell Significance Index: -8.4000 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0164
Cell Significance Index: -10.2500 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0166
Cell Significance Index: -0.7400 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0169
Cell Significance Index: -2.8800 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0184
Cell Significance Index: -1.2400 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.0197
Cell Significance Index: -1.4000 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.0206
Cell Significance Index: -0.7800 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0215
Cell Significance Index: -6.1800 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0258
Cell Significance Index: -3.3300 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0271
Cell Significance Index: -3.9400 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.0278
Cell Significance Index: -0.4700 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.0335
Cell Significance Index: -0.8800 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0392
Cell Significance Index: -4.0000 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0407
Cell Significance Index: -4.6600 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0499
Cell Significance Index: -10.5200 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.0504
Cell Significance Index: -1.2600 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0545
Cell Significance Index: -4.1800 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.0659
Cell Significance Index: -1.7900 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0726
Cell Significance Index: -3.4100 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0777
Cell Significance Index: -9.1600 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.0781
Cell Significance Index: -2.5000 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.0789
Cell Significance Index: -4.8400 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0805
Cell Significance Index: -8.3800 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0859
Cell Significance Index: -6.4000 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.0959
Cell Significance Index: -1.9900 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.0990
Cell Significance Index: -7.8400 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.1046
Cell Significance Index: -2.2200 - Cell Name: melanocyte of skin (CL1000458)
Fold Change: -0.1056
Cell Significance Index: -1.4800 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.1198
Cell Significance Index: -1.7200 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.1319
Cell Significance Index: -4.2000 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.1335
Cell Significance Index: -4.3700 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.1405
Cell Significance Index: -2.8200 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.1464
Cell Significance Index: -3.9200 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.1532
Cell Significance Index: -3.0300 - Cell Name: radial glial cell (CL0000681)
Fold Change: -0.1668
Cell Significance Index: -0.9900 - Cell Name: epithelial cell of uterus (CL0002149)
Fold Change: -0.1687
Cell Significance Index: -2.3400 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -0.1689
Cell Significance Index: -2.1000 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.1718
Cell Significance Index: -6.0200 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: -0.1765
Cell Significance Index: -2.2600 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.1772
Cell Significance Index: -5.2200 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.1779
Cell Significance Index: -4.7500 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.1787
Cell Significance Index: -3.8600 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.1953
Cell Significance Index: -5.0200 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.1964
Cell Significance Index: -4.9000 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.2009
Cell Significance Index: -5.7300
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2684923086
Symbol: ZNF74_HUMAN
Name: Zinc finger protein 74
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8663113
Title: The KRAB zinc finger gene ZNF74 encodes an RNA-binding protein tightly associated with the nuclear matrix.
PubMed ID: 8663113
PubMed ID: 8268910
Title: Isolation of a zinc finger gene consistently deleted in DiGeorge syndrome.
PubMed ID: 8268910
PubMed ID: 15461802
Title: A genome annotation-driven approach to cloning the human ORFeome.
PubMed ID: 15461802
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 10591208
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 1639391
Title: Cloning of six new genes with zinc finger motifs mapping to short and long arms of human acrocentric chromosome 22 (p and q11.2).
PubMed ID: 1639391
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 11705709
Title: Association of ZNF74 gene genotypes with age-at-onset of schizophrenia.
PubMed ID: 11705709
Sequence Information:
- Length: 644
- Mass: 72207
- Checksum: 87E5AA122BBC82F1
- Sequence:
MEIPAPEPEK TALSSQDPAL SLKENLEDIS GWGLPEARSK ESVSFKDVAV DFTQEEWGQL DSPQRALYRD VMLENYQNLL ALGPPLHKPD VISHLERGEE PWSMQREVPR GPCPEWELKA VPSQQQGICK EEPAQEPIME RPLGGAQAWG RQAGALQRSQ AAPWAPAPAM VWDVPVEEFP LRCPLFAQQR VPEGGPLLDT RKNVQATEGR TKAPARLCAG ENASTPSEPE KFPQVRRQRG AGAGEGEFVC GECGKAFRQS SSLTLHRRWH SREKAYKCDE CGKAFTWSTN LLEHRRIHTG EKPFFCGECG KAFSCHSSLN VHQRIHTGER PYKCSACEKA FSCSSLLSMH LRVHTGEKPY RCGECGKAFN QRTHLTRHHR IHTGEKPYQC GSCGKAFTCH SSLTVHEKIH SGDKPFKCSD CEKAFNSRSR LTLHQRTHTG EKPFKCADCG KGFSCHAYLL VHRRIHSGEK PFKCNECGKA FSSHAYLIVH RRIHTGEKPF DCSQCWKAFS CHSSLIVHQR IHTGEKPYKC SECGRAFSQN HCLIKHQKIH SGEKSFKCEK CGEMFNWSSH LTEHQRLHSE GKPLAIQFNK HLLSTYYVPG SLLGAGDAGL RDVDPIDALD VAKLLCVVPP RAGRNFSLGS KPRN
Genular Protein ID: 2148652258
Symbol: A8K5P3_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 644
- Mass: 72216
- Checksum: 778D76B1E773813F
- Sequence:
MEIPAPEPEK TALSSQDPAL SLKENLEDIS GWGLPEARSK ESVSFKDVAV DFTQEEWGQL DSPQRALYRD VMLENYQNLL ALGPPLHKPD VISHLERGEE PWSMQREVPR GPCPEWKLKA VPSQQQGICK EEPAQEPIME RPLGGAQAWG RQAGALQRSQ AAPWAPAPAM VWDVPVEEFP LRCPLFAQQR VPEGGPLLDT RKNVQATEGR TKAPARLCAG ENASTPSEPE KFPQVRRQRG AGAGEGEFVC GECGKAFRQS SSLTLHRRWH SREKAYKCDE CGKAFTWSTN LLEHRRIHTG EKPFFCGECG KAFSCHSSLN VHQRIHTGER PYKCSACEKA FSCSSLLSMH LRVHTGEKPY RCGECGKAFN QRTHLTRHHR IHTGEKPYQC GSCGKAFTCH SSLTVHEKIH SGDKPFKCSD CEKAFNSRSR LTLHQRTHTG EKPFKCADCG KGFSCHAYLL VHRRIHSGEK PFKCNECGKA FSSHAYLIVH RRIHTGEKPF DCSQCWKAFS CHSSLIVHQR IHTGEKPYKC SECGRAFSQN HCLIKHQKIH SGEKSFKCEK CGEMFNWSPH LTEHQRLHSE GKPLAIQFNK HLLSTYYVPG SLLGAGDAGL RDVDPIDALD VAKLLCVVPP RAGRNFSLGS KPRN
Genular Protein ID: 1687818831
Symbol: Q05BG0_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 573
- Mass: 64238
- Checksum: EE6D5480A1720D44
- Sequence:
MLENYQNLLA LGPPLHKPDV ISHLERGEEP WSMQREVPRG PCPEWELKAV PSQQQGICKE EPAQEPIMER PLGGAQAWGR QAGALQRSQA APWAPAPAMV WDVPVEEFPL RCPLFAQQCV PEGGPLLDTR KNVQATEGRT KAPARLCAGE NASTPSEPEK FPQVRRQRGA GAGEGEFVCG ECGKAFRQSS SLTLHRRWHS REKAYKCDEC GKAFTWSTNL LEHRRIHTGE KPFFCGECGK AFSCHSSLNV HQRIHTGERP YKCSACEKAF SCSSLLSMHL RVHTGEKPYR CGECGKAFNQ RTHLTRHHRI HTGEKPYQCG SCGKAFTCHS SLTVHEKIHS GDKPFKCSDC EKAFNSRSRL TLHQRTHTGE KPFKCADCGK GFSCHAYLLV HRRIHSGEKP FKCNECGKAF SSHAYLIVHR RIHTGEKPFD CSQCWKAFSC HSSLIVHQRI HTGEKPYKCS ECGRAFSQNH CLIKHQKIHS GEKSFKCEKC GEMFNWSSHL TEHQRLHSEG KPLAIQFNKH LLSTYYVPGS LLGAGDAGLR DVDPIDALDV AKLLCVVPPR AGRNFSLGSK PRN
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.