Details for: PLA2G7

Gene ID: 7941

Symbol: PLA2G7

Ensembl ID: ENSG00000146070

Description: phospholipase A2 group VII

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 72.9048
    Cell Significance Index: -11.3400
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 28.1495
    Cell Significance Index: -13.2900
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 26.5965
    Cell Significance Index: -10.8100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 9.1974
    Cell Significance Index: -11.3400
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 1.3095
    Cell Significance Index: 20.2600
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 1.1154
    Cell Significance Index: 18.7600
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.8649
    Cell Significance Index: 23.1400
  • Cell Name: monocyte-derived dendritic cell (CL0011031)
    Fold Change: 0.7404
    Cell Significance Index: 12.7200
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.4115
    Cell Significance Index: 81.6600
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.3603
    Cell Significance Index: 6.6600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.2721
    Cell Significance Index: 10.3100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.2170
    Cell Significance Index: 9.6000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.1814
    Cell Significance Index: 36.3800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0847
    Cell Significance Index: 58.5700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0337
    Cell Significance Index: 4.6300
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.0220
    Cell Significance Index: 0.3000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0023
    Cell Significance Index: -1.2600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0053
    Cell Significance Index: -10.0200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0063
    Cell Significance Index: -3.9100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0068
    Cell Significance Index: -5.0700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0085
    Cell Significance Index: -4.8000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0089
    Cell Significance Index: -16.4100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0100
    Cell Significance Index: -4.4300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0112
    Cell Significance Index: -17.2000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0129
    Cell Significance Index: -17.4900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0140
    Cell Significance Index: -2.5200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0160
    Cell Significance Index: -12.0800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0182
    Cell Significance Index: -11.5300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0187
    Cell Significance Index: -3.9300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0201
    Cell Significance Index: -7.2100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0240
    Cell Significance Index: -2.4500
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: -0.0243
    Cell Significance Index: -0.3000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0299
    Cell Significance Index: -13.5800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0308
    Cell Significance Index: -2.1800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0310
    Cell Significance Index: -8.9200
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0356
    Cell Significance Index: -1.5500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0406
    Cell Significance Index: -6.9300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0427
    Cell Significance Index: -5.2600
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0511
    Cell Significance Index: -1.1200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0521
    Cell Significance Index: -6.6800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0809
    Cell Significance Index: -11.7600
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.0815
    Cell Significance Index: -9.3000
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0845
    Cell Significance Index: -4.2700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0965
    Cell Significance Index: -12.4700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0985
    Cell Significance Index: -11.4800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1100
    Cell Significance Index: -12.9700
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.1104
    Cell Significance Index: -0.9000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1109
    Cell Significance Index: -11.5500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1232
    Cell Significance Index: -14.1100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1233
    Cell Significance Index: -6.4200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.1423
    Cell Significance Index: -3.8000
  • Cell Name: elicited macrophage (CL0000861)
    Fold Change: -0.1453
    Cell Significance Index: -1.2700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1620
    Cell Significance Index: -12.4400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1713
    Cell Significance Index: -12.7700
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.1748
    Cell Significance Index: -7.1600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1840
    Cell Significance Index: -12.3700
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: -0.1882
    Cell Significance Index: -2.0000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1943
    Cell Significance Index: -5.4300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1969
    Cell Significance Index: -12.1000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1978
    Cell Significance Index: -12.7600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.2079
    Cell Significance Index: -9.7700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.2131
    Cell Significance Index: -5.8000
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2242
    Cell Significance Index: -7.1400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2294
    Cell Significance Index: -12.8800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.2304
    Cell Significance Index: -10.7400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.2335
    Cell Significance Index: -12.1300
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.2444
    Cell Significance Index: -3.5000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2554
    Cell Significance Index: -13.4100
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2629
    Cell Significance Index: -9.2100
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: -0.2701
    Cell Significance Index: -2.8000
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.2809
    Cell Significance Index: -7.2200
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: -0.2969
    Cell Significance Index: -4.3100
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: -0.3122
    Cell Significance Index: -4.0400
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.3266
    Cell Significance Index: -4.3400
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.3335
    Cell Significance Index: -10.9200
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.3378
    Cell Significance Index: -7.1700
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: -0.3412
    Cell Significance Index: -4.9900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.3462
    Cell Significance Index: -12.0300
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.3621
    Cell Significance Index: -7.7400
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.3779
    Cell Significance Index: -7.9100
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.3883
    Cell Significance Index: -11.0800
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.3901
    Cell Significance Index: -11.4900
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.3935
    Cell Significance Index: -7.7800
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.4039
    Cell Significance Index: -2.4400
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.4075
    Cell Significance Index: -14.9600
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.4086
    Cell Significance Index: -6.9400
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: -0.4114
    Cell Significance Index: -4.8400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.4118
    Cell Significance Index: -14.4700
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: -0.4136
    Cell Significance Index: -3.3500
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.4138
    Cell Significance Index: -11.8600
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.4221
    Cell Significance Index: -4.9600
  • Cell Name: macrophage (CL0000235)
    Fold Change: -0.4231
    Cell Significance Index: -4.3200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.4260
    Cell Significance Index: -11.4200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.4290
    Cell Significance Index: -11.2800
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.4338
    Cell Significance Index: -12.7400
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.4404
    Cell Significance Index: -8.6100
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.4411
    Cell Significance Index: -11.0000
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.4418
    Cell Significance Index: -11.0200
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.4494
    Cell Significance Index: -7.1300
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.4662
    Cell Significance Index: -9.3600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** PLA2G7 is a member of the phospholipase A2 family, which consists of enzymes that hydrolyze ester bonds in phospholipids, leading to the production of bioactive lipid mediators. PLA2G7 exhibits a unique combination of high-density lipoprotein (HDL) particle-binding and calcium-independent phospholipase A2 activity, distinguishing it from other family members. This enzyme is predominantly expressed in cells of the immune system, including macrophages, dendritic cells, and epithelial cells, as well as in fetal tissues and neurons. **Pathways and Functions:** PLA2G7 is involved in various signaling pathways, including: 1. **Lipid Oxidation**: PLA2G7 catalyzes the hydrolysis of phospholipids, releasing arachidonic acid, which is then converted to eicosanoids, pro-inflammatory mediators. 2. **Inflammation**: The enzyme regulates the production of platelet-activating factor (PAF), a potent pro-inflammatory mediator that promotes leukocyte migration and activation. 3. **Antioxidant Defense**: PLA2G7 participates in the metabolism of oxidized phospholipids, which are generated during lipid peroxidation. 4. **Neuroprotection**: In the central nervous system, PLA2G7 is involved in the regulation of GABAergic signaling and the maintenance of neuronal homeostasis. **Clinical Significance:** PLA2G7 has been implicated in various diseases, including: 1. **Atherosclerosis**: Elevated PLA2G7 expression has been linked to the formation and progression of atherosclerotic plaques. 2. **Inflammatory Disorders**: Dysregulation of PLA2G7 has been observed in conditions such as rheumatoid arthritis, multiple sclerosis, and asthma. 3. **Neurodegenerative Diseases**: PLA2G7 has been implicated in the pathogenesis of Alzheimer's disease, Parkinson's disease, and other neurodegenerative disorders. 4. **Cancer**: The enzyme has been shown to contribute to cancer progression and metastasis, particularly in ovarian and breast cancers. In conclusion, PLA2G7 is a complex enzyme with diverse functions that underpin various physiological and pathological processes. Further research is needed to fully elucidate the mechanisms by which PLA2G7 regulates inflammation, lipid metabolism, and other cellular processes, with the ultimate goal of developing targeted therapies for the treatment of diseases associated with PLA2G7 dysregulation.

Genular Protein ID: 2511538300

Symbol: PAFA_HUMAN

Name: Platelet-activating factor acetylhydrolase

UniProtKB Accession Codes:

Q13093 A5HTT5 Q15692 Q5VTT1 Q8IVA2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 2 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChEBI 75 ChEMBL 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 2 DrugCentral 1 EC 1 EMBL 6 ESTHER 1 Ensembl 2 EvolutionaryTrace 1 GO 16 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 33 PDBsum 33 PIR 1 PIRSF 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 3 Rhea 30 SABIO-RK 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissLipids 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7700381

Title: Anti-inflammatory properties of a platelet-activating factor acetylhydrolase.

PubMed ID: 7700381

DOI: 10.1038/374549a0

PubMed ID: 8624782

Title: Purification, properties, sequencing, and cloning of a lipoprotein-associated, serine-dependent phospholipase involved in the oxidative modification of low-density lipoproteins.

PubMed ID: 8624782

DOI: 10.1161/01.atv.16.4.591

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2040620

Title: Human plasma platelet-activating factor acetylhydrolase. Oxidatively fragmented phospholipids as substrates.

PubMed ID: 2040620

DOI: 10.1016/s0021-9258(18)99132-5

PubMed ID: 7592717

Title: Plasma platelet-activating factor acetylhydrolase is a secreted phospholipase A2 with a catalytic triad.

PubMed ID: 7592717

DOI: 10.1074/jbc.270.43.25481

PubMed ID: 10504265

Title: Membrane-bound plasma platelet activating factor acetylhydrolase acts on substrate in the aqueous phase.

PubMed ID: 10504265

DOI: 10.1021/bi991149u

PubMed ID: 10066756

Title: Molecular basis of the interaction between plasma platelet-activating factor acetylhydrolase and low density lipoprotein.

PubMed ID: 10066756

DOI: 10.1074/jbc.274.11.7018

PubMed ID: 11590221

Title: N-linked glycosylation of macrophage-derived PAF-AH is a major determinant of enzyme association with plasma HDL.

PubMed ID: 11590221

PubMed ID: 12821559

Title: Platelet-activating factor acetylhydrolase is mainly associated with electronegative low-density lipoprotein subfraction.

PubMed ID: 12821559

DOI: 10.1161/01.cir.0000072791.40232.8f

PubMed ID: 16371369

Title: Release of free F2-isoprostanes from esterified phospholipids is catalyzed by intracellular and plasma platelet-activating factor acetylhydrolases.

PubMed ID: 16371369

DOI: 10.1074/jbc.m507340200

PubMed ID: 17090529

Title: Phospholipase action of platelet-activating factor acetylhydrolase, but not paraoxonase-1, on long fatty acyl chain phospholipid hydroperoxides.

PubMed ID: 17090529

DOI: 10.1074/jbc.m608135200

PubMed ID: 18434304

Title: Identification of a domain that mediates association of platelet-activating factor acetylhydrolase with high density lipoprotein.

PubMed ID: 18434304

DOI: 10.1074/jbc.m802394200

PubMed ID: 18784071

Title: Crystal structure of human plasma platelet-activating factor acetylhydrolase: structural implication to lipoprotein binding and catalysis.

PubMed ID: 18784071

DOI: 10.1074/jbc.m804750200

PubMed ID: 19394314

Title: Crystal structures of human group-VIIA phospholipase A2 inhibited by organophosphorus nerve agents exhibit non-aged complexes.

PubMed ID: 19394314

DOI: 10.1016/j.bcp.2009.04.018

PubMed ID: 8675689

Title: Platelet-activating factor acetylhydrolase deficiency. A missense mutation near the active site of an anti-inflammatory phospholipase.

PubMed ID: 8675689

DOI: 10.1172/jci118733

PubMed ID: 9245731

Title: Loss of activity of plasma platelet-activating factor acetylhydrolase due to a novel Gln281-->Arg mutation.

PubMed ID: 9245731

DOI: 10.1006/bbrc.1997.7047

PubMed ID: 9412624

Title: A mutation in plasma platelet-activating factor acetylhydrolase (Val279-->Phe) is a genetic risk factor for stroke.

PubMed ID: 9412624

DOI: 10.1161/01.str.28.12.2417

PubMed ID: 9472966

Title: Identification of the G994--> T missense in exon 9 of the plasma platelet-activating factor acetylhydrolase gene as an independent risk factor for coronary artery disease in Japanese men.

PubMed ID: 9472966

DOI: 10.1016/s0026-0495(98)90216-5

PubMed ID: 9759612

Title: A mutation in plasma platelet-activating factor acetylhydrolase (Val279Phe) is a genetic risk factor for cerebral hemorrhage but not for hypertension.

PubMed ID: 9759612

PubMed ID: 10733466

Title: The Ile198Thr and Ala379Val variants of plasmatic PAF-acetylhydrolase impair catalytical activities and are associated with atopy and asthma.

PubMed ID: 10733466

DOI: 10.1086/302901

Sequence Information:

  • Length: 441
  • Mass: 50077
  • Checksum: 3BA9EEA9E8094A57
  • Sequence:
    • MVPPKLHVLF CLCGCLAVVY PFDWQYINPV AHMKSSAWVN KIQVLMAAAS FGQTKIPRGN 
GPYSVGCTDL MFDHTNKGTF LRLYYPSQDN DRLDTLWIPN KEYFWGLSKF LGTHWLMGNI 
LRLLFGSMTT PANWNSPLRP GEKYPLVVFS HGLGAFRTLY SAIGIDLASH GFIVAAVEHR 
DRSASATYYF KDQSAAEIGD KSWLYLRTLK QEEETHIRNE QVRQRAKECS QALSLILDID 
HGKPVKNALD LKFDMEQLKD SIDREKIAVI GHSFGGATVI QTLSEDQRFR CGIALDAWMF 
PLGDEVYSRI PQPLFFINSE YFQYPANIIK MKKCYSPDKE RKMITIRGSV HQNFADFTFA 
TGKIIGHMLK LKGDIDSNVA IDLSNKASLA FLQKHLGLHK DFDQWDCLIE GDDENLIPGT 
NINTTNQHIM LQNSSGIEKY N

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.