Details for: ARHGEF5

Gene ID: 7984

Symbol: ARHGEF5

Ensembl ID: ENSG00000050327

Description: Rho guanine nucleotide exchange factor 5

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 45.8388
    Cell Significance Index: -7.1300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 27.5978
    Cell Significance Index: -7.0000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 6.3892
    Cell Significance Index: -6.1000
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 5.7747
    Cell Significance Index: -7.1200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 3.6065
    Cell Significance Index: 103.9100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 3.4752
    Cell Significance Index: 75.2900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 3.0681
    Cell Significance Index: 159.3800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 2.9965
    Cell Significance Index: 135.8200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 2.7764
    Cell Significance Index: 37.8800
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 2.0967
    Cell Significance Index: -6.4400
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 1.9601
    Cell Significance Index: 29.3700
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.5481
    Cell Significance Index: 92.9400
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 1.2657
    Cell Significance Index: -2.7700
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.1938
    Cell Significance Index: 129.8500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.1433
    Cell Significance Index: 31.1200
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 0.9659
    Cell Significance Index: 8.2100
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 0.8612
    Cell Significance Index: 5.3000
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.8423
    Cell Significance Index: 11.9900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.8205
    Cell Significance Index: 133.4400
  • Cell Name: large intestine goblet cell (CL1000320)
    Fold Change: 0.7409
    Cell Significance Index: 8.0300
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.6960
    Cell Significance Index: 16.0800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.6850
    Cell Significance Index: 47.3700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.6799
    Cell Significance Index: 67.2600
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.6499
    Cell Significance Index: 5.9900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.6484
    Cell Significance Index: 13.8100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.5988
    Cell Significance Index: 73.6300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.5682
    Cell Significance Index: 19.9700
  • Cell Name: epithelial cell of lacrimal sac (CL1000436)
    Fold Change: 0.4975
    Cell Significance Index: 3.5800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.4569
    Cell Significance Index: 34.0500
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: 0.3897
    Cell Significance Index: 4.0200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.3449
    Cell Significance Index: 62.1800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.3247
    Cell Significance Index: 143.5500
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: 0.3152
    Cell Significance Index: 2.0600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.3084
    Cell Significance Index: 21.8100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2795
    Cell Significance Index: 152.6500
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 0.2319
    Cell Significance Index: 2.4000
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.2298
    Cell Significance Index: 207.5300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.2180
    Cell Significance Index: 5.8200
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 0.2108
    Cell Significance Index: 1.3100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.2038
    Cell Significance Index: 9.5000
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 0.1949
    Cell Significance Index: 2.5100
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 0.1923
    Cell Significance Index: 3.2400
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.1684
    Cell Significance Index: 2.4900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.1575
    Cell Significance Index: 7.4000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.1539
    Cell Significance Index: 4.3000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.1336
    Cell Significance Index: 8.4200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.1215
    Cell Significance Index: 15.7000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1163
    Cell Significance Index: 22.1300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.1038
    Cell Significance Index: 15.1000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0963
    Cell Significance Index: 19.1100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0745
    Cell Significance Index: 10.2300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.0734
    Cell Significance Index: 8.4100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0539
    Cell Significance Index: 9.2100
  • Cell Name: epidermal cell (CL0000362)
    Fold Change: 0.0466
    Cell Significance Index: 0.1100
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: 0.0418
    Cell Significance Index: 0.5800
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.0386
    Cell Significance Index: 1.9500
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 0.0339
    Cell Significance Index: 0.3600
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: 0.0196
    Cell Significance Index: 0.2000
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: 0.0178
    Cell Significance Index: 0.1100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0110
    Cell Significance Index: 8.0300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0054
    Cell Significance Index: 10.2300
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.0035
    Cell Significance Index: 0.1800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0033
    Cell Significance Index: 2.1000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0019
    Cell Significance Index: 1.4200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0016
    Cell Significance Index: 3.0300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0014
    Cell Significance Index: 2.1000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0042
    Cell Significance Index: -5.7500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0049
    Cell Significance Index: -3.6300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0062
    Cell Significance Index: -0.2000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0069
    Cell Significance Index: -3.1500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0090
    Cell Significance Index: -5.0700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0095
    Cell Significance Index: -2.7200
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.0121
    Cell Significance Index: -0.1300
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0125
    Cell Significance Index: -7.7800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0129
    Cell Significance Index: -1.6600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0152
    Cell Significance Index: -1.5500
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: -0.0157
    Cell Significance Index: -0.1300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0186
    Cell Significance Index: -6.6600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0215
    Cell Significance Index: -2.5100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0304
    Cell Significance Index: -0.7600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0317
    Cell Significance Index: -6.6900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0345
    Cell Significance Index: -6.9300
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0430
    Cell Significance Index: -5.0700
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: -0.0469
    Cell Significance Index: -0.5500
  • Cell Name: oral mucosa squamous cell (CL1001576)
    Fold Change: -0.0477
    Cell Significance Index: -0.4100
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.0560
    Cell Significance Index: -1.9500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0601
    Cell Significance Index: -4.7600
  • Cell Name: secretory cell (CL0000151)
    Fold Change: -0.0634
    Cell Significance Index: -0.4400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0636
    Cell Significance Index: -6.6200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0665
    Cell Significance Index: -4.0800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0848
    Cell Significance Index: -6.5100
  • Cell Name: stem cell (CL0000034)
    Fold Change: -0.0881
    Cell Significance Index: -0.6400
  • Cell Name: intrahepatic cholangiocyte (CL0002538)
    Fold Change: -0.0903
    Cell Significance Index: -0.3400
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: -0.0916
    Cell Significance Index: -0.8700
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0938
    Cell Significance Index: -6.0500
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0959
    Cell Significance Index: -1.9900
  • Cell Name: intestinal crypt stem cell (CL0002250)
    Fold Change: -0.1108
    Cell Significance Index: -0.7800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1240
    Cell Significance Index: -6.9600
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.1247
    Cell Significance Index: -2.1000
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.1301
    Cell Significance Index: -1.9600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** ARHGEF5 is a member of the Rho guanine nucleotide exchange factor (GEF) family, which is responsible for activating Rho GTPases, a family of small GTP-binding proteins that regulate actin cytoskeleton organization, cell migration, and cell proliferation. ARHGEF5 is specifically involved in regulating the activity of RhoA, RhoC, and Rac1, which are key effectors of the Rho GTPase family. The gene is highly expressed in various cell types, including bladder urothelial cells, Paneth cells, and hematopoietic stem cells, suggesting its importance in maintaining tissue homeostasis and immune function. **Pathways and Functions:** ARHGEF5 is involved in a wide range of signaling pathways, including: 1. **Actin Cytoskeleton Organization:** ARHGEF5 regulates the activity of RhoA and Rac1, which are essential for maintaining actin cytoskeleton organization, cell migration, and cell proliferation. 2. **Cell Death Signaling:** ARHGEF5 interacts with NRAGE, NRIF, and NADE, which are involved in cell death signaling pathways, including apoptosis and necroptosis. 3. **Hematopoietic Stem Cell Homeostasis:** ARHGEF5 regulates the activity of RhoA and Rac1, which are essential for maintaining hematopoietic stem cell homeostasis and preventing leukemia. 4. **Immune Cell Function:** ARHGEF5 is highly expressed in immune cells, including myeloid dendritic cells, T cells, and B cells, suggesting its importance in regulating immune cell function and preventing autoimmune diseases. 5. **Cancer Progression:** ARHGEF5 is overexpressed in various types of cancer, including colorectal, breast, and lung cancer, suggesting its role in promoting cancer progression and metastasis. **Clinical Significance:** Dysregulation of ARHGEF5 has been implicated in various diseases, including: 1. **Cancer:** ARHGEF5 overexpression is associated with poor prognosis and metastasis in various types of cancer. 2. **Autoimmune Diseases:** ARHGEF5 is involved in regulating immune cell function, and its dysregulation may contribute to autoimmune diseases, such as rheumatoid arthritis and lupus. 3. **Neurological Disorders:** ARHGEF5 is involved in regulating actin cytoskeleton organization and cell migration, and its dysregulation may contribute to neurological disorders, such as Alzheimer's disease and Parkinson's disease. 4. **Infectious Diseases:** ARHGEF5 is involved in regulating immune cell function, and its dysregulation may contribute to infectious diseases, such as tuberculosis and HIV. In conclusion, ARHGEF5 is a complex gene that plays a crucial role in regulating actin cytoskeleton organization, cell signaling, and cell death. Its dysregulation has been implicated in various diseases, including cancer, autoimmune diseases, neurological disorders, and infectious diseases. Further research is needed to fully understand the mechanisms of ARHGEF5 and its role in human disease.

Genular Protein ID: 3674811034

Symbol: ARHG5_HUMAN

Name: Rho guanine nucleotide exchange factor 5

UniProtKB Accession Codes:

Q12774 A6NNJ2 Q6ZML7

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 3 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 7 Ensembl 2 ExpressionAtlas 1 GO 25 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 10 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 8 RefSeq 1 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8134109

Title: Expression cDNA cloning of a novel oncogene with sequence similarity to regulators of small GTP-binding proteins.

PubMed ID: 8134109

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14662653

Title: Expression and molecular characterization of alternative transcripts of the ARHGEF5/TIM oncogene specific for human breast cancer.

PubMed ID: 14662653

DOI: 10.1093/hmg/ddh024

PubMed ID: 15601624

Title: TIM, a Dbl-related protein, regulates cell shape and cytoskeletal organization in a Rho-dependent manner.

PubMed ID: 15601624

DOI: 10.1016/j.cellsig.2004.09.012

PubMed ID: 15848799

Title: Eph-dependent tyrosine phosphorylation of ephexin1 modulates growth cone collapse.

PubMed ID: 15848799

DOI: 10.1016/j.neuron.2005.01.030

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 25911094

Title: Odontogenic ameloblast-associated protein (ODAM) Mediates Junctional Epithelium Attachment to Tooth via Integrin-ODAM-Rho guanine nucleotide exchange factor 5 (ARHGEF5)-Ras homolog gene family member A (RhoA) Signaling.

PubMed ID: 25911094

DOI: 10.1074/jbc.m115.648022

Sequence Information:

  • Length: 1597
  • Mass: 176799
  • Checksum: 93EC1B1D7E1198C5
  • Sequence:
    • MEAEEAQRGA SPPISAIEEF SIIPEAPMRS SQVSALGLEA QEDEDPSYKW REEHRLSATQ 
QSELRDVCDY AIETMPSFPK EGSADVEPNQ ESLVAEACDT PEHWEAVPQS LAGRQARTLA 
PPELWACPIQ SEHLDMAPFS SDLGSEEEEV EFWPGLTSLT LGSGQAEEEE ETSSDNSGQT 
RYYSPCEEHP AETNQNEGSE SGTIRQGEEL PPEELQESQG LLHPQEVQVL EEQGQQEAGF 
RGEGTLREDV CADGLLGEEQ MIEQVNDEKG EQKQKQEQVQ DVMLGRQGER MGLTGEPEGL 
NDGEWEQEDM ERKAQGQGGP EQGEERKREL QVPEENRADS QDEKSQTFLG KSEEVTGKQE 
DHGIKEKGVP VSGQEAKEPE SWDGGRLGAV GRARSREEEN EHHGPSMPAL IAPEDSPHCD 
LFPGASYLMT QIPGTQTESR AEELSPAALS PSLEPIRCSH QPISLLGSFL TEESPDKEID 
QNSQQEESRL RKGTVSSQGT EVVFASASVT PPRTPDSAPP SPAEAYPITP ASVSARPPVA 
FPRRETSCAA RAPETASAPL SMDDPSPCGT SEMCPAALYG FPSTGTSPPR PPANSTGTVQ 
HLRSDSFPGS HRTEQTPDLV GMLLSYSHSE LPQRPPKPAI YSSVTPRRDR RSGRDYSTVS 
ASPTALSTLK QDSQESISNL ERPSSPPSIQ PWVSPHNPAF ATESPAYGSS PSFVSMEDVR 
IHEPLPPPPP QRRDTHPSVV ETDGHARVVV PTLKQHSHPP PLALGSGLHA PHKGPLPQAS 
DPAVARQHRP LPSTPDSSHH AQATPRWRYN KPLPPTPDLP QPHLPPISAP GSSRIYRPLP 
PLPIIDPPTE PPPLPPKSRG RSRSTRGGHM NSGGHAKTRP ACQDWTVPLP ASAGRTSWPP 
ATARSTESFT STSRSKSEVS PGMAFSNMTN FLCPSSPTTP WTPELQGPTS KDEAGVSEHP 
EAPAREPLRR TTPQQGASGP GRSPVGQARQ PEKPSHLHLE KASSWPHRRD SGRPPGDSSG 
QAVAPSEGAN KHKGWSRQGL RRPSILPEGS SDSRGPAVEK HPGPSDTVVF REKKPKEVMG 
GFSRRCSKLI NSSQLLYQEY SDVVLNKEIQ SQQRLESLSE TPGPSSPRQP RKALVSSESY 
LQRLSMASSG SLWQEIPVVR NSTVLLSMTH EDQKLQEVKF ELIVSEASYL RSLNIAVDHF 
QLSTSLRATL SNQEHQWLFS RLQDVRDVSA TFLSDLEENF ENNIFSFQVC DVVLNHAPDF 
RRVYLPYVTN QTYQERTFQS LMNSNSNFRE VLEKLESDPV CQRLSLKSFL ILPFQRITRL 
KLLLQNILKR TQPGSSEEAE ATKAHHALEQ LIRDCNNNVQ SMRRTEELIY LSQKIEFECK 
IFPLISQSRW LVKSGELTAL EFSASPGLRR KLNTRPVHLH LFNDCLLLSR PREGSRFLVF 
DHAPFSSIRG EKCEMKLHGP HKNLFRLFLR QNTQGAQAEF LFRTETQSEK LRWISALAMP 
REELDLLECY NSPQVQCLRA YKPRENDELA LEKADVVMVT QQSSDGWLEG VRLSDGERGW 
FPVQQVEFIS NPEVRAQNLK EAHRVKTAKL QLVEQQA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.