Details for: PPFIA4

Gene ID: 8497

Symbol: PPFIA4

Ensembl ID: ENSG00000143847

Description: PTPRF interacting protein alpha 4

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 51.6473
    Cell Significance Index: -13.1000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 26.9288
    Cell Significance Index: -10.9400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 10.3248
    Cell Significance Index: -12.7300
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 3.0434
    Cell Significance Index: 52.1600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.4532
    Cell Significance Index: 291.5200
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 1.3771
    Cell Significance Index: 17.0800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 1.2708
    Cell Significance Index: 56.2100
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 1.1799
    Cell Significance Index: 33.6700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 1.1369
    Cell Significance Index: 43.0500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 1.1095
    Cell Significance Index: 74.6000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.8778
    Cell Significance Index: 314.8600
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: 0.7331
    Cell Significance Index: 9.7800
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.6019
    Cell Significance Index: 13.1800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.5259
    Cell Significance Index: 363.7400
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 0.4963
    Cell Significance Index: 12.1100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.4574
    Cell Significance Index: 35.1000
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 0.2214
    Cell Significance Index: 5.5200
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: 0.1542
    Cell Significance Index: 2.0000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.1459
    Cell Significance Index: 8.9700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.1312
    Cell Significance Index: 6.8900
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 0.1051
    Cell Significance Index: 1.0000
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.0555
    Cell Significance Index: 1.3300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0510
    Cell Significance Index: 69.3300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0500
    Cell Significance Index: 9.9300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0413
    Cell Significance Index: 63.5500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0325
    Cell Significance Index: 61.1300
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 0.0313
    Cell Significance Index: 0.2400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0271
    Cell Significance Index: 50.0200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0093
    Cell Significance Index: 4.2300
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: 0.0056
    Cell Significance Index: 0.0700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0021
    Cell Significance Index: 1.1300
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0047
    Cell Significance Index: -0.0700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0073
    Cell Significance Index: -4.6600
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0124
    Cell Significance Index: -0.5400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0142
    Cell Significance Index: -6.2800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0164
    Cell Significance Index: -12.0000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0176
    Cell Significance Index: -13.0100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0194
    Cell Significance Index: -14.6800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0218
    Cell Significance Index: -12.2900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0231
    Cell Significance Index: -3.3600
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0315
    Cell Significance Index: -0.8100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0358
    Cell Significance Index: -10.3000
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0400
    Cell Significance Index: -0.8500
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -0.0413
    Cell Significance Index: -0.5300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0448
    Cell Significance Index: -8.0700
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0448
    Cell Significance Index: -0.9000
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.0521
    Cell Significance Index: -0.4300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0566
    Cell Significance Index: -6.6000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0635
    Cell Significance Index: -13.3800
  • Cell Name: type II muscle cell (CL0002212)
    Fold Change: -0.0657
    Cell Significance Index: -1.0600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0675
    Cell Significance Index: -6.9000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0708
    Cell Significance Index: -9.0700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0730
    Cell Significance Index: -12.4600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0784
    Cell Significance Index: -10.7600
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0796
    Cell Significance Index: -1.1400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0799
    Cell Significance Index: -9.8300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0877
    Cell Significance Index: -2.4500
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0928
    Cell Significance Index: -2.3200
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.0943
    Cell Significance Index: -1.1900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0954
    Cell Significance Index: -12.3200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0972
    Cell Significance Index: -11.4600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0980
    Cell Significance Index: -10.2000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1014
    Cell Significance Index: -3.3200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1040
    Cell Significance Index: -11.9200
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.1184
    Cell Significance Index: -1.2900
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.1234
    Cell Significance Index: -2.4400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.1255
    Cell Significance Index: -6.5200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1308
    Cell Significance Index: -7.3400
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1309
    Cell Significance Index: -4.1700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1452
    Cell Significance Index: -6.7700
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1521
    Cell Significance Index: -12.0500
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.1624
    Cell Significance Index: -3.3900
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: -0.1626
    Cell Significance Index: -2.3700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1663
    Cell Significance Index: -10.4800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1668
    Cell Significance Index: -12.4300
  • Cell Name: melanocyte of skin (CL1000458)
    Fold Change: -0.1741
    Cell Significance Index: -2.4400
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.1763
    Cell Significance Index: -3.8100
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.1804
    Cell Significance Index: -6.3200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1916
    Cell Significance Index: -12.3600
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1947
    Cell Significance Index: -10.1400
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.2036
    Cell Significance Index: -1.9300
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.2194
    Cell Significance Index: -4.6900
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.2237
    Cell Significance Index: -2.6100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.2293
    Cell Significance Index: -14.0600
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: -0.2366
    Cell Significance Index: -3.6000
  • Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
    Fold Change: -0.2393
    Cell Significance Index: -2.6400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.2410
    Cell Significance Index: -11.3300
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.2433
    Cell Significance Index: -3.0700
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.2463
    Cell Significance Index: -7.7900
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.2550
    Cell Significance Index: -3.0500
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.2618
    Cell Significance Index: -9.6100
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.2628
    Cell Significance Index: -6.9100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.2676
    Cell Significance Index: -12.1300
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.2944
    Cell Significance Index: -5.0900
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.3055
    Cell Significance Index: -7.6300
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.3064
    Cell Significance Index: -6.0300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.3185
    Cell Significance Index: -11.1900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.3522
    Cell Significance Index: -12.2400
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.3527
    Cell Significance Index: -2.3900
  • Cell Name: L5/6 near-projecting glutamatergic neuron of the primary motor cortex (CL4023043)
    Fold Change: -0.3642
    Cell Significance Index: -3.6800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** PPFIA4 is a gene that interacts with the receptor-type tyrosine-protein phosphatases (RPTPs), which are crucial for regulating the activity of various neurotransmitters. The gene is also involved in protein binding and protein-protein interactions at synapses, highlighting its role in modulating synaptic transmission. Additionally, PPFIA4 is significantly expressed in specific types of neurons, including interneurons and projecting neurons, suggesting its importance in neuronal development and function. **Pathways and Functions** The PPFIA4 gene is involved in multiple neurotransmitter release cycles, including: 1. Acetylcholine neurotransmitter release cycle: PPFIA4 interacts with RPTPs to regulate the activity of acetylcholine, a neurotransmitter involved in muscle contraction and other physiological processes. 2. Dopamine neurotransmitter release cycle: PPFIA4 is involved in the regulation of dopamine, a neurotransmitter involved in motivation, reward, and other cognitive processes. 3. Glutamate neurotransmitter release cycle: PPFIA4 interacts with RPTPs to regulate the activity of glutamate, the primary excitatory neurotransmitter in the central nervous system. 4. Norepinephrine neurotransmitter release cycle: PPFIA4 is involved in the regulation of norepinephrine, a neurotransmitter involved in attention, arousal, and other physiological processes. 5. Serotonin neurotransmitter release cycle: PPFIA4 interacts with RPTPs to regulate the activity of serotonin, a neurotransmitter involved in mood regulation, appetite, and other physiological processes. Furthermore, PPFIA4 is involved in protein-protein interactions at synapses, which are essential for regulating synaptic transmission. This gene's functions are critical for maintaining the integrity and function of the neuronal system. **Clinical Significance** Dysregulation of PPFIA4 has been implicated in various neurological disorders, including: 1. Neurodegenerative diseases: PPFIA4 has been shown to be involved in the pathogenesis of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. 2. Neuropsychiatric disorders: PPFIA4 has been implicated in the development of neuropsychiatric disorders, such as schizophrenia and bipolar disorder. 3. Developmental disorders: PPFIA4 has been shown to play a critical role in neuronal development and function, and its dysregulation has been implicated in developmental disorders, such as autism spectrum disorder. In conclusion, PPFIA4 is a critical gene involved in the regulation of neurotransmitter release cycles and protein-protein interactions at synapses. Its dysregulation has been implicated in various neurological and neuropsychiatric disorders, highlighting the importance of further research into the functions and mechanisms of this gene.

Genular Protein ID: 2265477988

Symbol: LIPA4_HUMAN

Name: Liprin-alpha-4

UniProtKB Accession Codes:

O75335 A2RUJ5 B1APN8 B1N949 B7ZM43 O94971

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CDD 3 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 10 Ensembl 3 ExpressionAtlas 1 GO 5 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 Proteomes 1 ProteomicsDB 3 RNAct 1 Reactome 6 RefSeq 2 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9624153

Title: Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins.

PubMed ID: 9624153

DOI: 10.1074/jbc.273.25.15611

PubMed ID: 10048485

Title: Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10048485

DOI: 10.1093/dnares/5.6.355

PubMed ID: 14612982

Title: Identification and characterization of human PPFIA4 gene in silico.

PubMed ID: 14612982

Sequence Information:

  • Length: 1185
  • Mass: 134404
  • Checksum: 0DD1431820D2313E
  • Sequence:
    • MCEVMPTINE GDRLGPPHGA DADANFEQLM VNMLDEREKL LESLRESQET LAATQSRLQD 
AIHERDQLQR HLNSALPQEF ATLTRELSMC REQLLEREEE ISELKAERNN TRLLLEHLEC 
LVSRHERSLR MTVVKRQAQS PSGVSSEVEV LKALKSLFEH HKALDEKVRE RLRAALERVT 
TLEEQLAGAH QQVSALQQGA GVRDGAAEEE GTVELGPKRL WKEDTGRVEE LQELLEKQNF 
ELSQARERLV TLTTTVTELE EDLGTARRDL IKSEELSSKH QRDLREALAQ KEDMEERITT 
LEKRYLAAQR EATSIHDLND KLENELANKE SLHRQCEEKA RHLQELLEVA EQKLQQTMRK 
AETLPEVEAE LAQRIAALTK AEERHGNIEE HLRQLEGQLE EKNQELARTA VQVRQREKMN 
EDHNKRLSDT VDRLLSESNE RLQLHLKERM AALEEKNTLI QELESSQRQI EEQHHHKGRL 
SEEIEKLRQE VDQLKGRGGP FVDGVHSRSH MGSAADVRFS LGTTTHAPPG VHRRYSALRE 
ESAKLALPLT VTLRSPTWMR MSQGVCCNLE YHSSGTLCGS SGPLPVPEMI QEEKESTELR 
AEEIETRVTS GSMEALNLKQ LRKRGSIPTS LTALSLASAS PPLSGRSTPK LTSRSAAQDL 
DRMGVMTLPS DLRKHRRKLL SPVSREENRE DKATIKCETS PPSSPRTLRL EKLGHPALSQ 
EEGKSALEDQ GSNPSSSNSS QDSLHKGAKR KGIKSSIGRL FGKKEKGRLI QLSRDGATGH 
VLLTDSEFSM QEPMVPAKLG TQAEKDRRLK KKHQLLEDAR RKGMPFAQWD GPTVVSWLEL 
WVGMPAWYVA ACRANVKSGA IMSALSDTEI QREIGISNAL HRLKLRLAIQ EMVSLTSPSA 
PPTSRTSSGN VWVTHEEMET LETSTKTDSE EGSWAQTLAY GDMNHEWIGN EWLPSLGLPQ 
YRSYFMECLV DARMLDHLTK KDLRVHLKMV DSFHRTSLQY GIMCLKRLNY DRKELEKRRE 
ESQHEIKDVL VWTNDQVVHW VQSIGLRDYA GNLHESGVHG ALLALDENFD HNTLALILQI 
PTQNTQARQV MEREFNNLLA LGTDRKLDDG DDKVFRRAPS WRKRFRPREH HGRGGMLSAS 
AETLPAGFRV STLGTLQPPP APPKKIMPEA HSHYLYGHML SAFRD

Genular Protein ID: 3078851765

Symbol: B4DIS5_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DIS5

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 Gene3D 1 InterPro 6 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 2 RefSeq 2 SAM 2 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 914
  • Mass: 103136
  • Checksum: 4931F22E52BA038E
  • Sequence:
    • MEERITTLEK RYLAAQREAT SIHDLNDKLE NELANKESLH RQCEEKARHL QELLEVAEQK 
LQQTMRKAET LPEVEAELAQ RIAALTKAEE RHGNIEEHLR QLEGQLEEKN QELARVRQRE 
KMNEDHNKRL SDTVDRLLSE SNERLQLHLK ERMAALEEKN TLIQELESSQ RQIEEQHHHK 
GRLSEEIEKL RQEVDQLKGR GGPFVDGVHS RSHMGSAADV RFSLGTTTHA PPGVHRRYSA 
LREESAKDWE TSPLPGMLAP AAGPAFDSDP EISDVDEDEP GGLVGSADVV SPSGHSDAQT 
LAMMLQEQLD AINEEIRMIQ EEKESTELRA EEIETRVTSG SMEALNLKQL RKRGSIPTSL 
TALSLASASP PLSGRSTPKL TSRSAAQDLD RMGVMTLPSD LRKHRRKLLS PVSREENRED 
KATIKCETSP PSSPRTLRLE KLGHPALSQE EGKSALEDQG SNPSSSNSSQ DSLHKGAKRK 
GIKSSIGRLF GKKEKGRLIQ LSRDGATGHV LLTDSEFSMQ EPMVPAKLGT QSEKDRRLKK 
KHQLLEDARR KGMPFAQWDG PTVVSWLELW VGMPAWYVAA CRANVKSGAI MSALSDTEIQ 
REIGISNALH RLKLRLAIQE MVSLTSPSAP PTSRTSSGNV WVTHEEMETL ETSTKTDSEE 
GSWAQTLAYG DMNHEWIGNE WLPSLGLPQY RSYFMECLVD ARMLDHLTKK DLRVHLKMVD 
SFHRTSLQYG IMCLKRLNHD RKELEKRREE SQHEIKDVLV WTNDQVVHWV QSIGLRDYAG 
NLHESGVHGA LLALDENFDH NTLALILQIP TQNTQARQVM EREFNNLLAL GTDRKLDDGD 
DKVFRRAPSW RKRFRPREHH GRGGMLSASA ETLPAGFRVS TLGTLQPPPA PPKKIMPEAH 
SHYLYGHMLS AFRD

Genular Protein ID: 4203951458

Symbol: B3KN22_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KN22

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 Gene3D 1 InterPro 6 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 1 SAM 1 SMART 1 SUPFAM 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 373
  • Mass: 42575
  • Checksum: EC5D90694A1812E8
  • Sequence:
    • MQEPMVPAKL GTQAEKDRRL KKKHQLLEDA RRKGMPFAQW DGPTVVSWLE LWVGMPAWYV 
AACRANVKSG AIMSALSDTE IQREIGISNA LHRLKLRLAI QEMVSLTSPS APPTSRTSSG 
NVWVTHEEME TLETSTKTTL AYGDMNHEWI GNEWLPSLGL PQYRSYFMEC LVDARMLDHL 
TKKDLRVHLK MVDSFHRTSL QYGIMCLKRL NYDRKELEKR REESQHEIKD VLVWTNDQVV 
HWVQSIGLRD YAGNLHESGV HGALLALDEN FDHNTLALIL QIPTQNTQAR QVMEREFNNL 
LALGTDRKLD DGDDKVFRRA PSWRKRFRPR EHHGRGGMLS ASAETLPAGF RVSTLGTLQP 
PPAPPKKIMP EGE

Genular Protein ID: 3979862075

Symbol: A0A8J8YUZ5_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A8J8YUZ5

Database IDs:

ARBA 2 CDD 3 CTD 1 DisGeNET 1 EMBL 3 Ensembl 2 GO 4 Gene3D 1 GeneTree 1 HGNC 1 InterPro 6 MANE-Select 1 NCBI Taxonomy 1 PANTHER 2 PROSITE 2 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 2 SMART 1 SMR 1 SUPFAM 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

Sequence Information:

  • Length: 1207
  • Mass: 136608
  • Checksum: 23A0624D2CA01BCE
  • Sequence:
    • MCEVMPTINE GDRLGPPHGA DADANFEQLM VNMLDEREKL LESLRESQET LAATQSRLQD 
AIHERDQLQR HLNSALPQEF ATLTRELSMC REQLLEREEE ISELKAERNN TRLLLEHLEC 
LVSRHERSLR MTVVKRQAQS PSGVSSEVEV LKALKSLFEH HKALDEKVRE RLRAALERVT 
TLEEQLAGAH QQVSALQQGA GVRDGAAEEE GTVELGPKRL WKEDTGRVEE LQELLEKQNF 
ELSQARERLV TLTTTVTELE EDLGTARRDL IKSEELSSKH QRDLREALAQ KEDMEERITT 
LEKRYLAAQR EATSIHDLND KLENELANKE SLHRQCEEKA RHLQELLEVA EQKLQQTMRK 
AETLPEVEAE LAQRIAALTK AEERHGNIEE HLRQLEGQLE EKNQELARVR QREKMNEDHN 
KRLSDTVDRL LSESNERLQL HLKERMAALE EKNTLIQELE SSQRQIEEQH HHKGRLSEEI 
EKLRQEVDQL KGRGGPFVDG VHSRSHMGSA ADVRFSLGTT THAPPGVHRR YSALREESAK 
DWETSPLPGM LAPAAGPAFD SDPEISDVDE DEPGGLVGSA DVVSPSGHSD AQTLAMMLQE 
QLDAINEEIR MIQEEKESTE LRAEEIETRV TSGSMEALNL KQLRKRGSIP TSLTALSLAS 
ASPPLSGRST PKLTSRSAAQ DLDRMGVMTL PSDLRKHRRK LLSPVSREEN REDKATIKCE 
TSPPSSPRTL RLEKLGHPAL SQEEGKSALE DQGSNPSSSN SSQDSLHKGA KRKGIKSSIG 
RLFGKKEKGR LIQLSRDGAT GHVLLTDSEF SMQEPMVPAK LGTQAEKDRR LKKKHQLLED 
ARRKGMPFAQ WDGPTVVSWL ELWVGMPAWY VAACRANVKS GAIMSALSDT EIQREIGISN 
ALHRLKLRLA IQEMVSLTSP SAPPTSRTSS GNVWVTHEEM ETLETSTKTD SEEGSWAQTL 
AYGDMNHEWI GNEWLPSLGL PQYRSYFMEC LVDARMLDHL TKKDLRVHLK MVDSFHRTSL 
QYGIMCLKRL NYDRKELEKR REESQHEIKD VLVWTNDQVV HWVQSIGLRD YAGNLHESGV 
HGALLALDEN FDHNTLALIL QIPTQNTQAR QVMEREFNNL LALGTDRKLD DGDDKVFRRA 
PSWRKRFRPR EHHGRGGMLS ASAETLPAGF RVSTLGTLQP PPAPPKKIMP EAHSHYLYGH 
MLSAFRD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.